S. Oka

发表

Importin α1 (Rch1) Mediates Nuclear Translocation of Thioredoxin-binding Protein-2/Vitamin D3-up-regulated Protein 1*

Y. Ishii, H. Masutani, J. Yodoi, 2004, Journal of Biological Chemistry.

Modulation of signaling mechanisms in the heart by thioredoxin 1

J. Sadoshima, S. Oka, Narayani Nagarajan, 2017, Free radical biology & medicine.

Hippo Deficiency Leads to Cardiac Dysfunction Accompanied by Cardiomyocyte Dedifferentiation During Pressure Overload

Lai-Hua Xie, M. Abdellatif, D. Lim, 2019, Circulation research.

Thioredoxin 1-mediated Post-translational Modifications: Reduction, Transnitrosylation, Denitrosylation, and Related Proteomics Methodologies I. Introduction Ii. Trx Systems A. Trx1 and Related Proteins B. Ptms of Trx1 Iii. Trx Regulation of Target Proteins by Disulfide Bond Reduction A. Trx Regulat

V. Gladyshev, J. Sadoshima, M. Jain, 2022 .

Redox Regulatory Mechanism of Transnitrosylation by Thioredoxin

J. Sadoshima, M. Jain, Hong Li, 2010, Molecular & Cellular Proteomics.

The protective role of the transmembrane thioredoxin-related protein TMX in inflammatory liver injury.

H. Kiyonari, H. Masutani, J. Yodoi, 2013, Antioxidants & redox signaling.

Thioredoxin‐binding protein‐2 (TBP‐2): Its potential roles in the aging process

H. Masutani, S. Oka, Toru Yoshida, 2006, BioFactors.

Overexpression of Thioredoxin-1 in Transgenic Mice Attenuates Adriamycin-Induced Cardiotoxicity

H. Masutani, J. Yodoi, Zuyi Yuan, 2002, Circulation.

Hydrogen peroxide activates IκB kinases through phosphorylation of serine residues in the activation loops

H. Kamata, H. Hirata, S. Oka, 2002, FEBS letters.

Recruitment of RNA Polymerase II to Metabolic Gene Promoters Is Inhibited in the Failing Heart Possibly Through PGC-1&agr; (Peroxisome Proliferator-Activated Receptor-&ggr; Coactivator-1&agr;) Dysregulation

Danish Sayed, M. Abdellatif, J. Sadoshima, 2019, Circulation. Heart failure.

The role of thioredoxin in the aging process: involvement of oxidative stress.

H. Masutani, J. Yodoi, S. Oka, 2003, Antioxidants & redox signaling.

A redox-dependent mechanism for regulation of AMPK activation by Thioredoxin1 during energy starvation.

J. Sadoshima, Hong Li, P. Zhai, 2013, Cell metabolism.

The function of nicotinamide phosphoribosyltransferase in the heart.

J. Sadoshima, S. Oka, Chiao-Po Hsu, 2014, DNA repair.

Broad Suppression of NADPH Oxidase Activity Exacerbates Ischemia/Reperfusion Injury Through Inadvertent Downregulation of Hypoxia-inducible Factor-1&agr; and Upregulation of Peroxisome Proliferator–activated Receptor-&agr;

J. Sadoshima, R. Tian, P. Zhai, 2013, Circulation research.

YAP plays a crucial role in the development of cardiomyopathy in lysosomal storage diseases.

K. Guan, H. Shimokawa, J. Sadoshima, 2020, The Journal of clinical investigation.

β-Hydroxybutyrate, a Ketone Body, Potentiates the Antioxidant Defense via Thioredoxin 1 Upregulation in Cardiomyocytes

M. Abdellatif, J. Sadoshima, S. Oka, 2021, Antioxidants.

Nampt Potentiates Antioxidant Defense in Diabetic Cardiomyopathy

J. Sadoshima, P. Zhai, S. Oka, 2021, Circulation research.

Mitophagy Is Essential for Maintaining Cardiac Function During High Fat Diet-Induced Diabetic Cardiomyopathy

J. Sadoshima, A. Shirakabe, P. Zhai, 2019, Circulation research.

Thioredoxin-binding protein-2-like inducible membrane protein is a novel vitamin D3 and peroxisome proliferator-activated receptor (PPAR)gamma ligand target protein that regulates PPARgamma signaling.

H. Masutani, J. Yodoi, Dongmei Wang, 2006, Endocrinology.

Yes-Associated Protein (YAP) Facilitates Pressure Overload–Induced Dysfunction in the Diabetic Heart

H. Shimokawa, J. Sadoshima, P. Zhai, 2019, JACC. Basic to translational science.

Blockade of Fibroblast YAP Attenuates Cardiac Fibrosis and Dysfunction Through MRTF-A Inhibition

P. Zhai, S. Oka, M. Tallquist, 2020, JACC. Basic to translational science.

Thioredoxin binding protein-2/thioredoxin-interacting protein is a critical regulator of insulin secretion and peroxisome proliferator-activated receptor function.

H. Masutani, J. Yodoi, Mutsumi Watanabe, 2009, Endocrinology.

Alternative Mitophagy Protects the Heart Against Obesity-Associated Cardiomyopathy

J. Sadoshima, A. Shirakabe, P. Zhai, 2021, Circulation research.

Redox Regulatory Mechanism of Transnitrosylation by Thioredoxin* □ S

J. Sadoshima, M. Jain, S. Oka, 2010 .

Thioredoxin-binding protein-2 deficiency enhances methionine-choline deficient diet-induced hepatic steatosis but inhibits steatohepatitis in mice.

H. Masutani, J. Yodoi, S. Oka, 2009, Antioxidants & redox signaling.

Impaired fatty acid utilization in thioredoxin binding protein‐2 (TBP‐2)‐deficient mice: a unique animal model of Reye syndrome

H. Hirata, Y. Shinkai, H. Masutani, 2006, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

S. Ichinose, M. Isobe, D. Fraidenraich, 2019, The Journal of clinical investigation.

Epidermal growth factor receptor is modulated by redox through multiple mechanisms. Effects of reductants and H2O2.

H. Kamata, H. Hirata, S. Oka, 2000, European journal of biochemistry.

Dual PPARα/γ activation inhibitsSIRT1-PGC1α axis and causes cardiac dysfunction

M. Civelek, M. Madesh, Ying Tian, 2019, JCI Insight.

Perm1 regulates cardiac energetics as a downstream target of the histone methyltransferase Smyd1

M. A. Zaitsev, Y. Saijoh, J. Sadoshima, 2020, PloS one.

Dual peroxisome-proliferator-activated-receptor-a / g activation inhibits SIRT 1-PGC 1 a axis and causes cardiac dysfunction

Estela, M. Civelek, M. Madesh, 2019 .

Thioredoxin binding protein 2 modulates natural killer T cell-dependent innate immunity in the liver: possible link to lipid metabolism.

Y. Nabeshima, H. Masutani, J. Yodoi, 2009, Antioxidants & redox signaling.

The tumor suppressor RASSF1A modulates inflammation and injury in the reperfused murine myocardium

J. Sadoshima, P. Zhai, S. Oka, 2019, The Journal of Biological Chemistry.

Nicotinamide Mononucleotide, an Intermediate of NAD+ Synthesis, Protects the Heart from Ischemia and Reperfusion

J. Sadoshima, P. Zhai, S. Oka, 2014, PloS one.

Integrative Physiology Broad Suppression of NADPH Oxidase Activity Exacerbates Ischemia/Reperfusion Injury Through Inadvertent Downregulation of Hypoxia-inducible Factor-1 α and Upregulation of Peroxisome Proliferator–activated Receptor- α

J. Sadoshima, R. Tian, P. Zhai, 2013 .

Cycloprodigiosin hydrocloride suppresses tumor necrosis factor (TNF) α‐induced transcriptional activation by NF‐κB

H. Kamata, H. Hirata, H. Yagisawa, 2001 .

Thioredoxin-1 maintains mechanistic target of rapamycin (mTOR) function during oxidative stress in cardiomyocytes

J. Yodoi, Y. Hirabayashi, J. Sadoshima, 2017, The Journal of Biological Chemistry.

Control of Mitochondrial Outer Membrane Permeabilization and Bcl-xL Levels by Thioredoxin 2 in DT40 Cells*

Y. Yamaguchi-Iwai, H. Masutani, J. Yodoi, 2006, Journal of Biological Chemistry.

Thioredoxin-1 Ameliorates Myosin-Induced Autoimmune Myocarditis by Suppressing Chemokine Expressions and Leukocyte Chemotaxis in Mice

Y. Ishii, M. Tanito, J. Yodoi, 2004, Circulation.

Nicotinamide phosphoribosyltransferase regulates cell survival through autophagy in cardiomyocytes

N. Hariharan, J. Sadoshima, S. Oka, 2009, Autophagy.

Redox regulation of mast cell histamine release in thioredoxin-1 (TRX) transgenic mice

Y. Ishii, J. Yodoi, S. Oka, 2006, Cell Research.

Trx 1 as a co-factor of mTOR 1 Thioredoxin-1 maintains mTOR function during oxidative stress in cardiomyocytes

J. Yodoi, Y. Hirabayashi, J. Sadoshima, 2017 .

Broad Suppression of NADPH Oxidase Activity Exacerbates Ischemia/Reperfusion Injury Through Inadvertent Downregulation of HIF-1 and Upregulation of PPAR

J. Sadoshima, P. Zhai, S. Oka, 2013 .

Dendritic cells derived from TBP‐2‐deficient mice are defective in inducing T cell responses

Y. Ishii, H. Masutani, J. Yodoi, 2008, European journal of immunology.

Thioredoxin binding protein-2 mediates metabolic adaptation in response to lipopolysaccharide in vivo

H. Masutani, J. Yodoi, S. Oka, 2010, Critical care medicine.

YAP mediates compensatory cardiac hypertrophy through aerobic glycolysis in response to pressure overload

M. Abdellatif, J. Sadoshima, P. Zhai, 2022, The Journal of clinical investigation.

Tyrosine kinase FYN negatively regulates NOX4 in cardiac remodeling.

J. Sadoshima, Hong Li, P. Zhai, 2016, The Journal of clinical investigation.

Multiple Redox Regulation of the Cellular Signaling System Linked to AP‐1 and NFκB: Effects of N‐Acetylcysteine and H2O2 on the Receptor Tyrosine Kinases, the MAP Kinase Cascade, and IκB Kinases

H. Kamata, H. Hirata, S. Oka, 2002, Annals of the New York Academy of Sciences.

PERM1 regulates energy metabolism in the heart via ERRα/PGC−1α axis

Y. Saijoh, Hong Li, S. Oka, 2022, Frontiers in Cardiovascular Medicine.

Protective role of Pink1-mediated mitophagy in Angiotensin II-induced cardiac injury.

S. Oka, 2018, International journal of cardiology.

Molecular properties and regulation of NAD+ kinase (NADK)

J. Sadoshima, S. Oka, Daniela K. Zablocki, 2022, Redox biology.

Abstract B19: Neurofibromin 2 regulates metabolism in the heart

P. Zhai, S. Oka, Wataru Mizushima, 2020 .

KLF5 Is Induced by FOXO1 and Causes Oxidative Stress and Diabetic Cardiomyopathy.

W. Koch, V. Yang, J. Sadoshima, 2020, Circulation research.

Multiple Levels of PGC-1α Dysregulation in Heart Failure

S. Oka, Amira D. Sabry, Junco S. Warren, 2020, Frontiers in Cardiovascular Medicine.

N‐Acetylcysteine suppresses TNF‐induced NF‐κB activation through inhibition of IκB kinases

H. Kamata, H. Hirata, H. Yagisawa, 2000, FEBS letters.

Histone methyltransferase Smyd1 regulates mitochondrial energetics in the heart

Haley O. Tucker, O. Fiehn, S. Franklin, 2018, Proceedings of the National Academy of Sciences.

Loss of Thioredoxin-Binding Protein-2/Vitamin D3 Up-Regulated Protein 1 in Human T-Cell Leukemia Virus Type I-Dependent T-Cell Transformation

Y. Ishii, H. Masutani, J. Yodoi, 2004, Cancer Research.

Dual peroxisome-proliferator-activated-receptor-α/γ activation inhibits SIRT1-PGC1α axis and causes cardiac dysfunction.

M. Civelek, M. Madesh, Ying Tian, 2019, JCI insight.

Hydrogen peroxide sensing and signaling by protein kinases in the cardiovascular system.

P. Eaton, S. Oka, J. Burgoyne, 2013, Antioxidants & redox signaling.

Silent Information Regulator 1 Protects the Heart From Ischemia/Reperfusion

N. Hariharan, Y. Maejima, J. Sadoshima, 2010, Circulation.

AAV-mediated YAP expression in cardiac fibroblasts promotes inflammation and increases fibrosis

S. Oka, Dominic P. Del Re, A. Ivessa, 2021, Scientific Reports.

Redox regulation of nerve growth factor-induced neuronal differentiation of PC12 cells through modulation of the nerve growth factor receptor, TrkA.

H. Kamata, H. Hirata, S. Oka, 2005, Archives of biochemistry and biophysics.

An Ideal PPAR Response Element Bound to and Activated by PPARα

J. Sadoshima, S. Oka, Ji Yeon Park, 2015, PloS one.

Regulation of Cell Survival and Death by Pyridine Nucleotides

J. Sadoshima, S. Oka, Chiao-Po Hsu, 2012, Circulation research.

Metabolic reprogramming via PPARα signaling in cardiac hypertrophy and failure: From metabolomics to epigenetics.

J. Sadoshima, S. Oka, Daniela K. Zablocki, 2017, American journal of physiology. Heart and circulatory physiology.

Peroxisome Proliferator Activated Receptor-&agr; Association With Silent Information Regulator 1 Suppresses Cardiac Fatty Acid Metabolism in the Failing Heart

J. Sadoshima, P. Zhai, S. Oka, 2015, Circulation. Heart failure.

Identification of Novel Nuclear Targets of Human Thioredoxin 1*

J. Sadoshima, A. Kong, M. Jain, 2014, Molecular & Cellular Proteomics.

Redox modification of cell signaling in the cardiovascular system.

J. Sadoshima, P. Eaton, S. Oka, 2012, Journal of molecular and cellular cardiology.

Critical Roles of Thioredoxin in Nerve Growth Factor-Mediated Signal Transduction and Neurite Outgrowth in PC12 Cells

H. Masutani, J. Yodoi, S. Oka, 2003, The Journal of Neuroscience.

Attenuation of retinal photooxidative damage in thioredoxin transgenic mice

M. Tanito, H. Masutani, J. Yodoi, 2002, Neuroscience Letters.

Sirt1 carboxyl-domain is an ATP-repressible domain that is transferrable to other proteins

N. Tjandra, R. Ghirlando, J. Sadoshima, 2017, Nature Communications.

Thioredoxin-1 maintains mitochondrial function via mTOR signaling in the heart.

J. Yodoi, Y. Hirabayashi, J. Sadoshima, 2019, Cardiovascular research.

The role of redox modulation of class II histone deacetylases in mediating pathological cardiac hypertrophy

T. Kitazono, J. Sadoshima, S. Oka, 2009, Journal of Molecular Medicine.

Nicotinamide Phosphoribosyltransferase Regulates Cell Survival Through NAD+ Synthesis in Cardiac Myocytes

Dan Shao, Chiao-Po Hsu, N. Hariharan, 2009, Circulation research.

Proteomic analysis of mitochondrial biogenesis in cardiomyocytes differentiated from human induced pluripotent stem cells.

Lai-Hua Xie, D. Fraidenraich, J. Sadoshima, 2020, American journal of physiology. Regulatory, integrative and comparative physiology.

PPARα-Sirt1 complex mediates cardiac hypertrophy and failure through suppression of the ERR transcriptional pathway.

J. Sadoshima, P. Zhai, S. Oka, 2011, Cell metabolism.

PERM1 regulates genes involved in fatty acid metabolism in the heart by interacting with PPARα and PGC-1α

G. Yehia, J. Sadoshima, S. Oka, 2022, Scientific Reports.

Both gain and loss of Nampt function promote pressure-overload-induced heart failure.

J. Sadoshima, P. Zhai, S. Oka, 2019, American journal of physiology. Heart and circulatory physiology.

PPARα Association With Sirt1 Suppresses Cardiac Fatty Acid Metabolism in the Failing Heart

J. Sadoshima, P. Zhai, S. Oka, 2015 .

Suppression of ERR targets by a PPARα/Sirt1 complex in the failing heart

J. Sadoshima, P. Zhai, S. Oka, 2012, Cell cycle.

Molecular Cardiology Silent Information Regulator 1 Protects the Heart from Ischemia/reperfusion Clinical Perspective on P 2182

N. Hariharan, Y. Maejima, J. Sadoshima, 2022 .

Distinct Roles of DRP1 in Conventional and Alternative Mitophagy in Obesity Cardiomyopathy

J. Sadoshima, P. Zhai, S. Oka, 2023, Circulation research.

Suppression of myeloid YAP antagonizes adverse cardiac remodeling during pressure overload stress.

J. Sadoshima, P. Zhai, S. Oka, 2023, Journal of molecular and cellular cardiology.

Thioredoxin-1 maintains mitochondrial function via mechanistic target of rapamycin signalling in the heart

J. Yodoi, Y. Hirabayashi, J. Sadoshima, 2020 .