M. Sugiyama

发表

A polymerase chain reaction-mediated yeast artificial chromosome-splitting technology for generating targeted yeast artificial chromosomes subclones.

A. Kobayashi, Y. Kaneko, S. Harashima, 2006, Methods in molecular biology.

A versatile and general splitting technology for generating targeted YAC subclones

A. Kobayashi, Y. Kaneko, S. Harashima, 2005, Applied Microbiology and Biotechnology.

APPLIED GENETICS AND MOLECULAR BIOTECHNOLOGY

A. Kobayashi, S. Harashima, K. Fukui, 2005 .

Candida tropicalis Isolated from Tuak, a North Sumatera- Indonesian Traditional Beverage, for Bioethanol Production

Hermansyah, S. Harashima, M. Sugiyama, 2015 .

Lactic-acid stress causes vacuolar fragmentation and impairs intracellular amino-acid homeostasis in Saccharomyces cerevisiae.

Y. Kaneko, S. Harashima, M. Sugiyama, 2012, Journal of bioscience and bioengineering.

Enhanced bio-ethanol production from cellulosic materials by semi-simultaneous saccharification and fermentation using high temperature resistant Saccharomyces cerevisiae TJ14.

C. Boonchird, Y. Kaneko, S. Harashima, 2013, Journal of bioscience and bioengineering.

Repeated chromosome splitting targeted to δ sequences in Saccharomyces cerevisiae

Kiichi Fukui, Kyouhei Hayashi, Minetaka Sugiyama, 2003 .

Creating a Saccharomyces cerevisiae haploid strain having 21 chromosomes.

Y. Kaneko, S. Harashima, Y. Mukai, 2003, Journal of bioscience and bioengineering.

Type 2C protein phosphatase Ptc6 participates in activation of the Slt2-mediated cell wall integrity pathway in Saccharomyces cerevisiae.

S. Harashima, M. Sugiyama, Y. Sasano, 2015, Journal of bioscience and bioengineering.

Overexpression of ESBP6 improves lactic acid resistance and production in Saccharomyces cerevisiae.

Y. Kaneko, S. Harashima, M. Sugiyama, 2016, Journal of bioscience and bioengineering.

Genetic interactions of ribosome maturation factors Yvh1 and Mrt4 influence mRNA decay, glycogen accumulation, and the expression of early meiotic genes in Saccharomyces cerevisiae.

Y. Kaneko, S. Harashima, S. Nugroho, 2011, Journal of biochemistry.

Genome-wide mapping of unexplored essential regions in the Saccharomyces cerevisiae genome: evidence for hidden synthetic lethal combinations in a genetic interaction network

Y. Kaneko, S. Harashima, M. Sugiyama, 2014, Nucleic acids research.

Chromosome-shuffling technique for selected chromosomal segments in Saccharomyces cerevisiae

Y. Kaneko, S. Harashima, Y. Mukai, 2006, Applied Microbiology and Biotechnology.

Disruption of multiple genes whose deletion causes lactic-acid resistance improves lactic-acid resistance and productivity in Saccharomyces cerevisiae.

Y. Kaneko, S. Harashima, Takatoshi Sakamoto, 2013, Journal of bioscience and bioengineering.

Molecular breeding of Saccharomyces cerevisiae with high RNA content by harnessing essential ribosomal RNA transcription regulator

S. Harashima, M. Sugiyama, Y. Sasano, 2017, AMB Express.

Increased transcription of RPL40A and RPL40B is important for the improvement of RNA production in Saccharomyces cerevisiae.

Y. Kaneko, S. Harashima, F. Khatun, 2013, Journal of bioscience and bioengineering.

Construction of a Saccharomyces cerevisiae strain with a high level of RNA.

Y. Kaneko, S. Harashima, Yeonhee Kim, 2011, Journal of bioscience and bioengineering.

Construction and characterization of single-gene chromosomes in Saccharomyces cerevisiae.

Y. Kaneko, S. Harashima, M. Sugiyama, 2008, Journal of bioscience and bioengineering.

Increase in rRNA content in a Saccharomyces cerevisiae suppressor strain from rrn10 disruptant by rDNA cluster duplication

Y. Kaneko, S. Harashima, F. Khatun, 2013, Applied Microbiology and Biotechnology.

Suppression of the Saccharomyces cerevisiae hac1/ire15 mutation by yeast genes and human cDNAs.

J. Nikawa, K. Hayashi, M. Sugiyama, 1997, Gene.

Ketoacyl synthase domain is a major determinant for fatty acyl chain length in Saccharomyces cerevisiae

E. Fukusaki, T. Bamba, Y. Kaneko, 2013, Archives of Microbiology.

Modification of metabolic pathways of Saccharomyces cerevisiae by the expression of lactate dehydrogenase and deletion of pyruvate decarboxylase genes for the lactic acid fermentation at low pH value

Kazuyuki Shimizu, Minetaka Sugiyama, J. Nikawa, 1998 .

Highly efficient bioethanol production by a Saccharomyces cerevisiae strain with multiple stress tolerance to high temperature, acid and ethanol.

C. Boonchird, Y. Kaneko, S. Harashima, 2012, New biotechnology.

Functional analysis of very long-chain fatty acid elongase gene, HpELO2, in the methylotrophic yeast Hansenula polymorpha

E. Fukusaki, A. Kobayashi, T. Bamba, 2007, Applied Microbiology and Biotechnology.

Mechanism of Yeast Adaptation to Weak Organic Acid Stress

S. Harashima, M. Sugiyama, Y. Sasano, 2015 .

Harnessing nanoparticles for the efficient delivery of the CRISPR/Cas9 system

Thomas J. Webster, Soodabeh Davaran, Hossein Rahimi, 2020 .

Characterization and gene expression profiles of thermotolerant Saccharomyces cerevisiae isolates from Thai fruits.

C. Boonchird, Y. Kaneko, S. Harashima, 2012, Journal of bioscience and bioengineering.

Chromosome XII context is important for rDNA function in yeast

Y. Kaneko, S. Harashima, Yeonhee Kim, 2006, Nucleic acids research.

Identification of protein kinase disruptions as suppressors of the calcium sensitivity of S. cerevisiae Δptp2 Δmsg5 protein phosphatase double disruptant

Hermansyah, Y. Kaneko, S. Harashima, 2010, Archives of Microbiology.

Increase in rRNA content in a Saccharomyces cerevisiae suppressor strain from rrn10 disruptant by rDNA cluster duplication

Y. Kaneko, S. Harashima, F. Khatun, 2013, Applied Microbiology and Biotechnology.

Increased transcription of NOP15, involved in ribosome biogenesis in Saccharomyces cerevisiae, enhances the production yield of RNA as a source of nucleotide seasoning.

Fahmida Khatun, Minetaka Sugiyama, Satoshi Harashima, 2012, Journal of bioscience and bioengineering.

Genome-wide construction of a series of designed segmental aneuploids in Saccharomyces cerevisiae

Y. Kaneko, S. Harashima, M. Sugiyama, 2015, Scientific Reports.

Cellular mechanisms contributing to multiple stress tolerance in Saccharomyces cerevisiae strains with potential use in high-temperature ethanol fermentation

C. Boonchird, Y. Kaneko, S. Harashima, 2016, AMB Express.

CDC19 encoding pyruvate kinase is important for high-temperature tolerance in Saccharomyces cerevisiae.

C. Boonchird, Y. Kaneko, S. Harashima, 2012, New biotechnology.

Deciphering cellular functions of protein phosphatases by comparison of gene expression profiles in Saccharomyces cerevisiae.

S. Muta, S. Kuhara, Y. Kaneko, 2010, Journal of bioscience and bioengineering.

Effects of deletion of different PP2C protein phosphatase genes on stress responses in Saccharomyces cerevisiae

S. Harashima, M. Sugiyama, Y. Sasano, 2014, Yeast.

Cloning and functional analysis of HpFAD2 and HpFAD3 genes encoding Δ12- and Δ15-fatty acid desaturases in Hansenula polymorpha.

E. Fukusaki, T. Bamba, Y. Kaneko, 2014, Gene.

Analysis and enhancement of the ethanol resistance of Pichia kudriavzevii N77-4, a strain newly isolated from the Korean traditional fermentation starter Nuruk, for improved fermentation performance

S. Y. Kim, S. Yeo, M. Sugiyama, 2019, Journal of Physics: Conference Series.

Overexpression of PkINO1 improves ethanol resistance of Pichia kudriavzevii N77-4 isolated from the Korean traditional fermentation starter nuruk.

S. Yeo, M. Sugiyama, J. Mun, 2018, Journal of bioscience and bioengineering.

Improved stress resistance and ethanol production by segmental haploidization of the diploid genome in Saccharomyces cerevisiae.

S. Harashima, T. Miyamoto, M. Sugiyama, 2016, Journal of bioscience and bioengineering.

Nuclear Localization of Haa1, Which Is Linked to Its Phosphorylation Status, Mediates Lactic Acid Tolerance in Saccharomyces cerevisiae

Y. Kaneko, S. Harashima, H. Horie, 2014, Applied and Environmental Microbiology.

Superior thermotolerance of Saccharomyces cerevisiae for efficient bioethanol fermentation can be achieved by overexpression of RSP5 ubiquitin ligase.

Minetaka Sugiyama, Satoshi Harashima, Y. Kaneko, 2012, Biotechnology advances.

Saccharomyces cerevisiae protein phosphatase Ppz1 and protein kinases Sat4 and Hal5 are involved in the control of subcellular localization of Gln3 by likely regulating its phosphorylation state.

Y. Nogi, Y. Kaneko, S. Harashima, 2011, Journal of bioscience and bioengineering.

Ethanol production from biomass by repetitive solid-state fed-batch fermentation with continuous recovery of ethanol

S. Shioya, C. Boonchird, Y. Kaneko, 2010, Applied Microbiology and Biotechnology.

PCR-mediated one-step deletion of targeted chromosomal regions in haploid Saccharomyces cerevisiae

Y. Kaneko, S. Harashima, M. Sugiyama, 2008, Applied Microbiology and Biotechnology.

Yeast protein phosphatases Ptp2p and Msg5p are involved in G1–S transition, CLN2 transcription, and vacuole morphogenesis

Hermansyah, Y. Kaneko, S. Harashima, 2009, Archives of Microbiology.

Stabilization of mini-chromosome segregation during mitotic growth by overexpression of YCR041W and its application to chromosome engineering in Saccharomyces cerevisiae.

Y. Kaneko, S. Harashima, M. Sugiyama, 2015, Journal of bioscience and bioengineering.

The Saccharomycescerevisiae Isw2p-Itc1p Complex RepressesINO1 Expression and Maintains Cell Morphology

J. Nikawa, M. Sugiyama, 2001, Journal of bacteriology.

Effects of N-Glycosylation and Inositol on the ER Stress Response in Yeast Saccharomyces cerevisiae

J. Nikawa, M. Sugiyama, S. Uchimura, 2005, Bioscience, biotechnology, and biochemistry.

Creation of an ethanol-tolerant yeast strain by genome reconstruction based on chromosome splitting technology.

S. Harashima, Yeonhee Kim, M. Sugiyama, 2012, Journal of microbiology and biotechnology.

PCR-mediated repeated chromosome splitting in Saccharomyces cerevisiae.

Y. Kaneko, S. Harashima, M. Sugiyama, 2005, BioTechniques.

Suppression mechanism of the calcium sensitivity in Saccharomyces cerevisiae ptp2Δmsg5Δ double disruptant involves a novel HOG-independent function of Ssk2, transcription factor Msn2 and the protein kinase A component Bcy1.

Y. Kaneko, S. Harashima, M. Sugiyama, 2014, Journal of bioscience and bioengineering.

Molecular breeding of Saccharomyces cerevisiae with high RNA content by harnessing essential ribosomal RNA transcription regulator

S. Harashima, M. Sugiyama, Y. Sasano, 2017, AMB Express.

Ketoacyl synthase domain is a major determinant for fatty acyl chain length in Saccharomyces cerevisiae

E. Fukusaki, T. Bamba, Y. Kaneko, 2013, Archives of Microbiology.

Large scale deletions in the Saccharomyces cerevisiae genome create strains with altered regulation of carbon metabolism

Takahiro Sumiya, Minetaka Sugiyama, Satoshi Harashima, 2007, Applied Microbiology and Biotechnology.

Cellular mechanisms contributing to multiple stress tolerance in Saccharomyces cerevisiae strains with potential use in high-temperature ethanol fermentation

C. Boonchird, Y. Kaneko, S. Harashima, 2016, AMB Express.

Characterization and gene expression profiles of thermotolerant Saccharomyces cerevisiae isolates from Thai fruits.

C. Boonchird, Y. Kaneko, S. Harashima, 2012, Journal of bioscience and bioengineering.

The protein phosphatase Siw14 controls caffeine-induced nuclear localization and phosphorylation of Gln3 via the type 2A protein phosphatases Pph21 and Pph22 in Saccharomyces cerevisiae.

S. Harashima, H. Maekawa, M. Sugiyama, 2015, Journal of biochemistry.

Advances in molecular methods to alter chromosomes and genome in the yeast Saccharomyces cerevisiae

Y. Kaneko, S. Harashima, Yeonhee Kim, 2009, Applied Microbiology and Biotechnology.

Development and Application of Novel Genome Engineering Technologies in Saccharomyces cerevisiae

S. Harashima, M. Sugiyama, Y. Sasano, 2014 .

Construction of versatile yeast plasmid vectors transferable by Agrobacterium-mediated transformation and their application to bread-making yeast strains.

K. Kiyokawa, K. Moriguchi, M. Sugiyama, 2023, Journal of Bioscience and Bioengineering.

Large-scale genome reorganization in Saccharomyces cerevisiae through combinatorial loss of mini-chromosomes.

Y. Kaneko, S. Harashima, R. Matoba, 2012, Journal of bioscience and bioengineering.

Conditional chromosome splitting in Saccharomyces cerevisiae using the homing endonuclease PI-SceI

Y. Kaneko, S. Harashima, M. Sugiyama, 2008, Applied Microbiology and Biotechnology.