T. Miki

发表

A high-density STS map based on a single contig of YAC and P1 clones in the chromosome 8p12-p21 region.

T. Ogihara, A. Takahashi-Fujii, J. Nakura, 1997, Genomics.

A single ataxia telangiectasia gene with a product similar to PI-3 kinase.

M. Lovett, F. Collins, S. Weissman, 1995, Science.

Characteristics ofIntergenerationa l Contractions oftheCTG RepeatinMyotonic Dystrophy

A. Roses, H. Smeets, C. Junien, 1994 .

Expansion of unstable DNA region in Japanese myotonic dystrophy patients

T. Ogihara, M. Nakagawa, T. Miki, 1992, The Lancet.

Complex HLA-DR and -DQ interactions confer risk of narcolepsy-cataplexy in three ethnic groups.

N Risch, N. Risch, E. Mignot, 2001, American journal of human genetics.

Low density lipoprotein receptor‐related protein gene polymorphisms and risk for late‐onset Alzheimer's disease in a Japanese population

T. Ogihara, M. Imagawa, K. Fukuo, 2000, Clinical genetics.

Homozygosity mapping of the Werner syndrome locus (WRN).

J. Weber, G. Schellenberg, E. Wijsman, 1994, Genomics.

Angiotensin-converting-enzyme genotype and ischemic heart disease.

T. Ogihara, J. Higaki, H. Rakugi, 1995, The New England journal of medicine.

Polymorphism of angiotensin converting enzyme, angiotensinogen, and apolipoprotein E genes in a Japanese population with cerebrovascular disease.

T. Ogihara, J. Higaki, T. Katsuya, 1997, American journal of hypertension.

α1‐Antichymotrypsin as a risk modifier for late‐onset Alzheimer's disease in Japanese apolipoprotein E ε4 allele carriers

Toshio Ogihara, Toshiaki Sakai, T. Ogihara, 1997 .

Deletion Polymorphism Of Angiotensin‐Converting Enzyme Gene Is Associated With Postprandial Hyperglycaemia In Individuals Undergoing General Check‐Up

T. Ogihara, J. Higaki, T. Katsuya, 2000, Clinical and experimental pharmacology & physiology.

Polymorphism of the apolipoprotein E and angiotensin-converting enzyme genes in Japanese subjects with silent myocardial ischemia.

T. Ogihara, J. Higaki, T. Katsuya, 1996, Hypertension.

[Effects of pravastatin administration for 12 months on serum lipid levels in aged patients with hypercholesterolemia].

T. Ogihara, K. Fukuo, H. Ikegami, 1994, Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics.

Angiotensin II type 1 receptor gene polymorphism is associated with increase of left ventricular mass but not with hypertension.

T. Ogihara, J. Higaki, T. Katsuya, 1998, American journal of hypertension.

Loss of alleles at loci on chromosome 13 in human primary gastric cancers.

T. Honjo, I. Nishisho, T. Miki, 1988, Genomics.

Leukemia developing after 131I treatment for thyroid cancer in a patient with Werner's syndrome: molecular and cytogenetic studies.

T. Ogihara, N. Mitsuda, T. Miki, 1995, Internal medicine.

Association of variants in critical core promoter element of angiotensinogen gene with increased risk of essential hypertension in Japanese.

T. Ogihara, J. Higaki, T. Katsuya, 1997, Hypertension.

Genetic association study between senile dementia of Alzheimer's type and APOE/C1/C2 gene cluster.

T. Ogihara, M. Imagawa, T. Miki, 1996, Gerontology.

The 717Val----Ile substitution in amyloid precursor protein is associated with familial Alzheimer's disease regardless of ethnic groups.

T. Ogihara, Y. Sakaki, T. Katsuya, 1991, Biochemical and biophysical research communications.

Cloning of human immunoglobulin epsilon chain genes: evidence for multiple C epsilon genes.

T. Honjo, Y. Nishida, T. Miki, 1982, Proceedings of the National Academy of Sciences of the United States of America.

Three different mutations of presenilin 1 gene in early-onset Alzheimer's disease families

T. Ogihara, Y. Sakaki, P. George-Hyslop, 1996, Neuroscience Letters.

Assignment1 of the Ect2 protooncogene to mouse chromosome band 3B by in situ hybridization

S. Takai, T. Miki, M. Lorenzi, 1998, Cytogenetic and Genome Research.

Effects of individual mutations in the P-450(C21) pseudogene on the P-450(C21) activity and their distribution in the patient genomes of congenital steroid 21-hydroxylase deficiency.

Y. Fujii‐Kuriyama, J. Nakura, A. Tanae, 1991, Journal of biochemistry.

All patients with Werner's syndrome are insulin resistant, but only those who also have impaired insulin secretion develop overt diabetes.

T. Ogihara, H. Ikegami, T. Miki, 1999, Diabetes care.

D10S20, a previously unmapped RFLP (OS-3), is located on 10q near D10S4.

J. Kidd, A. Pakstis, Y. Chen, 1988, Genomics.

Assignment of the human TIM proto-oncogene to 7q33-->q35.

S. Takai, A. Chan, T. Miki, 1995, Cancer genetics and cytogenetics.

Molecular cloning and characterization of rab27a and rab27b, novel human rab proteins shared by melanocytes and platelets.

W. Gahl, T. Miki, M. Tachibana, 1997, Biochemical and molecular medicine.

Elevated amyloid β protein(1-40) level induces CREB phosphorylation at serine-133 via p44/42 MAP kinase (Erk1/2)-dependent pathway in rat pheochromocytoma PC12 cells

T. Ogihara, N. Sato, T. Miki, 1997 .

Molecular cloning of two novel rab genes from human melanocytes.

W. Gahl, T. Miki, M. Tachibana, 1996, Gene.

A case of first trimester prenatal diagnosis of 21-hydroxylase deficiency with human complement C4 cDNA probe.

T. Ogihara, J. Nakura, S. Takai, 1990, Endocrinologia japonica.

Mutational screening of APP gene in patients with early‐onset Alzheimer disease utilizing mismatched PCR‐RFLP

M. Takeda, M. Imagawa, T. Miki, 1996, Clinical genetics.

Linkage and haplotype analysis of familial early-onset Alzheimer disease in Japanese population

T. Ogihara, T. Bird, T. Katsuya, 1995, Japanese Journal of Human Genetics.

Analysis of steroid 21-hydroxylase gene in five unrelated Japanese patients with 21-hydroxylase deficiency.

T. Honjo, J. Nakura, P. White, 1987, Endocrinologia japonica.

Hypotensive effect associated with a phospholipase C-delta 1 gene mutation in the spontaneously hypertensive rat.

T. Ogihara, J. Higaki, T. Katsuya, 1992, Biochemical and biophysical research communications.

The zygosity determination of Japanese twins using a minisatellite core probe

A. Jeffreys, Takesada Mori, S. Takai, 1987, Japanese Journal of Human Genetics.

Gap junction protein locus on chromosome 18 cosegregates with body weight in the spontaneously hypertensive rat.

T. Ogihara, J. Higaki, T. Katsuya, 1995, Hypertension research : official journal of the Japanese Society of Hypertension.

Interphase detection of BCL6/IgH fusion gene in non-Hodgkin lymphoma by fluorescence in situ hybridization.

M. Taniwaki, H. Kaneko, S. Misawa, 1997, Cancer genetics and cytogenetics.

Absence of linkage disequilibrium at amyloid precursor protein gene locus in Japanese familia Alzheimer's disease with 717Val→Ile mutation

S. Tsuji, T. Miyatake, M. Imagawa, 1993, Neuroscience Letters.

Close linkage of the gene for Werner's syndrome to ANK1 and D8S87 on the short arm of chromosome 8.

J. Nakura, L. Ye, T. Miki, 1993, Gerontology.

A neuropeptide Y locus on chromosome 4 cosegregates with blood pressure in the spontaneously hypertensive rat.

T. Ogihara, J. Higaki, T. Katsuya, 1993, Biochemical and biophysical research communications.

Evidence against DNA polymerase β as a candidate gene for Werner syndrome

G. Schellenberg, C. Disteche, T. Ogihara, 1994, Human Genetics.

The complete nucleotide sequence of the influenza virus neuraminidase gene of A/NJ/8/76 strain and its evolution by segmental duplication and deletion.

T. Miyata, Y. Nishida, E. Ohtsuka, 1983, Molecular biology & medicine.

Analysis and comparison of new candidate loci for hypertension between genetic hypertensive rat strains.

T. Ogihara, J. Higaki, T. Katsuya, 1996, Hypertension research : official journal of the Japanese Society of Hypertension.

Association analysis of a polymorphism of the angiotensin converting enzyme gene with essential hypertension in the Japanese population.

T. Ogihara, J. Higaki, T. Katsuya, 1993, Biochemical and biophysical research communications.

Aphidicolin-resistant human cell lines resistant to uv and bleomycin

T. Ogihara, J. Nakura, Kiyoji Tanaka, 1993, In Vitro Cellular & Developmental Biology - Animal.

Mapping of the genes around MEN2A locus using pulsed-field gel electrophoresis

J. Nakura, Takesada Mori, S. Takai, 1990, Japanese Journal of Human Genetics.

Toward localization of the Werner syndrome gene by linkage disequilibrium and ancestral haplotyping: lessons learned from analysis of 35 chromosome 8p11.1-21.1 markers.

E M Wijsman, G. Schellenberg, E. Wijsman, 1996, American journal of human genetics.

Human FRAG1 encodes a novel membrane-spanning protein that localizes to chromosome 11p15.5, a region of frequent loss of heterozygosity in cancer.

C. Keck, T. Miki, M. Lorenzi, 1999, Genomics.

Cloning of MITF, the human homolog of the mouse microphthalmia gene and assignment to chromosome 3p14.1-p12.3.

U. Francke, L. Pérez-Jurado, T. Miki, 1994, Human molecular genetics.

Positional Cloning of the Werner's Syndrome Gene

G. Schellenberg, E. Wijsman, Chang-En Yu, 1996, Science.

Mutations in the consensus helicase domains of the Werner syndrome gene. Werner's Syndrome Collaborative Group.

G. Schellenberg, E. Wijsman, J. Nakura, 1997, American journal of human genetics.

Mapping of 20 polymorphic DNA markers in the rat by somatic hybrid and linkage analysis

G. Lathrop, T. Ogihara, T. Serikawa, 2009, Mammalian Genome.

SNP-based analysis of the HLA locus in Japanese multiple sclerosis patients

S. Hauser, J. Oksenberg, J. Kira, 2011, Genes and Immunity.

Population variation in the dinucleotide repeat polymorphism at the D8S360 locus.

N. Niikawa, T. Ohta, J. Nakura, 1993, Human molecular genetics.

Allele loss on chromosome 10 and point mutation of ras oncogenes are infrequent in tumors of MEN 2A.

A. Miyauchi, A. Miya, T. Miki, 1989, Henry Ford Hospital medical journal.

Loss of genes on chromosome 22 in medullary thyroid carcinoma and pheochromocytoma.

A. Miyauchi, S. Takai, I. Nishisho, 1987, Japanese journal of cancer research : Gann.

Isolation of DNA clones revealing restriction fragment length polymorphisms in the human genome

T. Honjo, J. Nakura, Takesada Mori, 1986, Japanese Journal of Human Genetics.

Chromosomal localization of the human ECT2 proto-oncogene to 3q26.1-->q26.2 by somatic cell analysis and fluorescence in situ hybridization.

S. Takai, T. Miki, J. Long, 1995, Genomics.

Association of a polymorphic variant of the Werner helicase gene with myocardial infarction in a Japanese population.

T. Ogihara, S. Edland, J. Higaki, 1997, American journal of medical genetics.

Comparison of the myotonic dystrophy associated CTG repeat in European and Japanese populations.

T. Ogihara, R. Williamson, M. Nakagawa, 1992, Journal of medical genetics.

Identification of a single base polymorphism in intron 2 of the c-fos gene and its detection by mismatched PCR-RFLP

T. Ogihara, T. Miki, K. Kamino, 1994, Japanese Journal of Human Genetics.

Linkage of human narcolepsy with HLA association to chromosome 4p13-q21.

T. Arinami, T. Miki, Y. Honda, 2000, Genomics.

Distribution and evolution of CTG repeats at the myotonin protein kinase gene in human populations.

R. Barrantes, M. Shriver, P. Majumder, 1996, Genome research.

Homozygous and compound heterozygous mutations at the Werner syndrome locus.

G. Schellenberg, T. Ogihara, J. Nakura, 1996, Human molecular genetics.

Multiple endocrine neoplasia type 2 syndromes in Japan.

A. Miyauchi, T. Miki, S. Takai, 1984, Henry Ford Hospital medical journal.

Localization of the human HER4/erbB-4 gene to chromosome 2.

M. Kraus, D. Zimonjic, M. Alimandi, 1995, Oncogene.

Clinical comparison of Alzheimer's disease in pedigrees with the codon 717 Val→Ile mutation in the amyloid precursor protein gene

Toru Shimizu, A. Roses, P. Lantos, 1993, Neurobiology of Aging.

Linkage disequilibrium and haplotype studies of chromosome 8p 11.1-21.1 markers and Werner syndrome.

G. Schellenberg, E. Wijsman, T. Ogihara, 1994, American journal of human genetics.

Isolation and mapping of microsatellites from a library microdissected from the Werner syndrome region, 8p11.2–p22

T. Ogihara, N. Niikawa, T. Ohta, 1993, Japanese Journal of Human Genetics.

Genetic variation at twentythree microsatellite loci in sixteen human populations

R. Barrantes, M. Shriver, C. Bunker, 2008, Journal of Genetics.

Deficiency in mitochondrial aldehyde dehydrogenase increases the risk for late-onset Alzheimer's disease in the Japanese population.

M. Imagawa, S. Kitamura, K. Namekata, 2000, Biochemical and biophysical research communications.

Congenital myotonic dystrophy transmitted from an asymptomatic father with a DM‐specific gene

N. Tachi, K. Ohya, S. Chiba, 1994, Neurology.

A case of paternally inherited congenital myotonic dystrophy.

T. Miki, M. Nakagawa, T. Miki, 1994, Journal of medical genetics.

A New Polymorphic ProbeWhichDefines theRegion of Chromosome19Containing theMyotonic Dystrophy Locus

E. Nimmo, H. Brunner, M. Siciliano, 1990 .

Characteristics of dynamic mutation in Japanese myotonic dystrophy

T. Ogihara, M. Nakagawa, T. Miki, 1994, Japanese Journal of Human Genetics.

A potent genetic risk factor for restenosis

T. Ogihara, J. Higaki, H. Rakugi, 1993, Nature Genetics.

Association of I27L polymorphism of hepatocyte nuclear factor-1 alpha gene with high-density lipoprotein cholesterol level.

T. Ogihara, J. Nakura, H. Ikegami, 2003, The Journal of clinical endocrinology and metabolism.

An intergenerational contraction of the CTG repeat in Japanese myotonic dystrophy

T. Takayanagi, T. Miki, H. Yamagata, 1996, Journal of the Neurological Sciences.

Haplotype analysis of congenital myotonic dystrophy patients from asymptomatic DM father.

N. Tachi, K. Ohya, S. Chiba, 1997, Pediatric neurology.

Carrier detection of Werner's syndrome using a microsatellite that exhibits linkage disequilibrium with the Werner's syndrome locus

T. Ogihara, J. Nakura, L. Ye, 1994, Japanese Journal of Human Genetics.

A new mitochondrial DNA mutation associated with non-insulin-dependent diabetes mellitus.

E. Yamato, Y. Uchigata, H. Ikegami, 1995, Biochemical and biophysical research communications.

Contribution of the activation of the ras oncogene to the evolution of aldosterone- and renin-secreting tumors.

T. Ogihara, R. Morishita, J. Higaki, 1991, Journal of hypertension.

Studies of multiple endocrine neoplasia type 2A syndrome: linkage analyses and comparison of constitutional and tumor genotypes.

A. Miyauchi, I. Nishisho, T. Miki, 1987, Henry Ford Hospital medical journal.

Preclinical detection of men 2A gene carrier using linked DNA markers

A. Miyauchi, S. Takai, I. Sakita, 1991, The Japanese Journal of Human Genetics.

An anonymous single copy chromosome 18 probe associated with a frequent RFLP (D18S5).

T. Honjo, I. Nishisho, T. Miki, 1986, Nucleic acids research.

Association analysis of a polymorphism of the angiotensinogen gene with essential hypertension in Japanese.

T. Ogihara, J. Higaki, H. Rakugi, 1994, Journal of human hypertension.

[An analysis of questionnaires about geriatric medicine/medical education sent to members of the Japanese Society of General Medicine].

T. Ogihara, J. Higaki, T. Miki, 1999, Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics.

Substrain comparison of genetically hypertensive rats using DNA fingerprinting, and genetic analysis of blood pressure in the inbred rats.

R. Morishita, J. Higaki, T. Katsuya, 1991, The Tohoku journal of experimental medicine.

A novel microsatellite polymorphism in the human OB gene: a highly polymorphic marker for linkage analysis

T. Ogihara, E. Yamato, H. Ikegami, 1996, Diabetologia.

[Linkage mapping].

T. Ogihara, T. Miki, L. Ye, 1996, Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme.

[The effect on age for the relationship between hypertension and glucose intolerance].

T. Ogihara, H. Ikegami, T. Fujisawa, 1993, Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics.

[Primary biliary cirrhosis with polymyositis successfully treated with prednisolone and ursodeoxycholic acid].

T. Ogihara, O. Yasuda, H. Rakugi, 1996, Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics.

Isolation of a novel oncogene, NET1, from neuroepithelioma cells by expression cDNA cloning.

S. Takai, A. Chan, T. Miki, 1996, Oncogene.

Assignment of a polymorphic locus of OS-4(D18S5) DNA segment to human chromosome region 18q21.3→qter

S. Takai, I. Nishisho, M. Yoshida, 1987, Japanese Journal of Human Genetics.

Normal CAG repeat variation at the DRPLA locus in world populations.

M. Shriver, C. Bunker, R. Chakraborty, 1995, American journal of human genetics.

Six dinucleotide repeat polymorphisms on chromosome 7

T. Ogihara, N. Niikawa, A. Takahashi-Fujii, 1994, Japanese Journal of Human Genetics.

Analysis of the apolipoprotein B3' hypervariable region in patients with essential hypertension.

T. Ogihara, J. Higaki, T. Miki, 1992, Clinical and experimental pharmacology & physiology. Supplement.

Molecular and epidemiological studies of Werner syndrome in the Japanese population

T. Ogihara, J. Nakura, L. Ye, 1997, Mechanisms of Ageing and Development.

Narrowing the position of the Werner syndrome locus by homozygosity analysis-extension of homozygosity analysis.

G. Schellenberg, E. Wijsman, T. Ogihara, 1996, Genomics.

Dinucleotide repeat polymorphism at the D8S1223 locus

T. Ogihara, J. Nakura, L. Ye, 1996, The Japanese Journal of Human Genetics.

Genetic association between chromosome 8 microsatellite (MS8-134) and Werner syndrome (WRN): chromosome microdissection and homozygosity mapping.

T. Ogihara, N. Niikawa, T. Ohta, 1995, Genomics.

Dinucleotide repeat polymorphism at the D8S1055

T. Ogihara, A. Takahashi-Fujii, J. Nakura, 1994, The Japanese Journal of Human Genetics.

Dinucleotide repeat polymorphism at the D8S1053

T. Ogihara, A. Takahashi-Fujii, J. Nakura, 1994, Japanese Journal of Human Genetics.

Dinucleotide repeat polymorphism at the D8S1054

T. Ogihara, A. Takahashi-Fujii, J. Nakura, 1995, Japanese Journal of Human Genetics.

Alzheimer's disease and DLST genotype

S. Ohta, K. Nishimaki, T. Miki, 1997, The Lancet.

Elevated amyloid beta protein(1-40) level induces CREB phosphorylation at serine-133 via p44/42 MAP kinase (Erk1/2)-dependent pathway in rat pheochromocytoma PC12 cells.

T. Ogihara, T. Miki, K. Kamino, 1997, Biochemical and Biophysical Research Communications - BBRC.

Characterization of complex chromosomal abnormalities in B‐cell lymphoma by a combined spectral karyotyping (SKY) analysis and fluorescence in situ hybridization (FISH) using a 14q telomere probe

N. Kakazu, T. Abe, T. Miki, 2000, American journal of hematology.

Close linkage of MEN2A with RBP3 locus in Japanese kindreds

A. Pakstis, T. Honjo, A. Miyauchi, 1989, Human Genetics.

T/G polymorphism at intron 9 of presenilin 1 gene is associated with, but not responsible for sporadic late-onset Alzheimer's disease in Japanese population

T. Ogihara, N. Sato, M. Takeda, 1997, Neuroscience Letters.

A Case of Pseudomyxoma Peritonei with Bilateral Pleural Metastases

T. Ogihara, T. Miki, Y. Kumahara, 1982 .

Tight linkage of the ret proto-oncogene with the multiple endocrine neoplasia type 2A locus.

T. Tahira, F. Itoh, A. Miya, 1991, Japanese journal of clinical oncology.

Loss of genes on the long arm of chromosome 22 in human meningiomas.

T. Honjo, I. Nishisho, T. Miki, 1988, Molecular biology & medicine.