S. Liebman

发表

Extrachromosomal psi+ determinant suppresses nonsense mutations in yeast

F. Sherman, S. Liebman, 1979, Journal of bacteriology.

The Yeast [PSI +] Prion: Making Sense of Nonsense*

S. Liebman, I. Derkatch, 1999, The Journal of Biological Chemistry.

Overexpression of the SUP45 gene encoding a Sup35p-binding protein inhibits the induction of the de novo appearance of the [PSI+] prion.

S. Liebman, I. Derkatch, M. E. Bradley, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Long non-coding RNA NEAT1_1 ameliorates TDP-43 toxicity in in vivo models of TDP-43 proteinopathy

T. Iwatsubo, T. Hashimoto, S. Liebman, 2021, RNA biology.

The ubiquitin-conjugating enzyme Rad6 (Ubc2) is required for silencing in Saccharomyces cerevisiae

D. Gottschling, L. Prakash, S. Liebman, 1997, Molecular and cellular biology.

A ubiquitin-conjugating enzyme, RAD6, affects the distribution of Ty1 retrotransposon integration positions.

S. Liebman, G. Newnam, 1993, Genetics.

An antisuppressor that acts on omnipotent suppressors in yeast.

S. Liebman, M. Cavenagh, 1980, Genetics.

Mutations in eukaryotic 18S ribosomal RNA affect translational fidelity and resistance to aminoglycoside antibiotics.

Y. Chernoff, S. Liebman, A. Vincent, 1994, The EMBO journal.

Integration of an aberrant retrotransposon in Saccharomyces cerevisiae

S. Liebman, C. Wilke, 1989 .

Protein folding: sticky N17 speeds huntingtin pile-up.

S. Liebman, S. Meredith, 2010, Nature chemical biology.

Rearrangements occurring adjacent to a single Ty1 yeast retrotransposon in the presence and absence of full-length Ty1 transcription.

S. Liebman, P. R. Sutton, 1992, Genetics.

A translational fidelity mutation in the universally conserved sarcin/ricin domain of 25S yeast ribosomal RNA.

S. Liebman, R. Liu, R. Liu, 1996, RNA.

Exploring the basis of [PIN(+)] variant differences in [PSI(+)] induction.

S. Liebman, J. Sharma, 2013, Journal of molecular biology.

Integration of an aberrant retrotransposon in Saccharomyces cerevisiae

S. Liebman, C. Wilke, 1989, Molecular and cellular biology.

Overexpression of the essential Sis1 chaperone reduces TDP-43 effects on toxicity and proteolysis

S. Liebman, F. Arslan, S. Barmada, 2017, PLoS genetics.

Mutations Affecting Translational Accuracy in Yeast

S. Liebman, A. Vincent, Jae Mahn Song, 1993 .

Mutations in RAD6, a yeast gene encoding a ubiquitin-conjugating enzyme, stimulate retrotransposition

S. Liebman, S. Picologlou, N. Brown, 1990, Molecular and cellular biology.

Baby, don't stop!

A. Mankin, S. Liebman, 1999, Nature Genetics.

How overexpression of Q/N proteins cures yeast prions

S. Liebman, I. Derkatch, 2013 .

The story of stolen chaperones

S. Liebman, I. Derkatch, 2013, Prion.

Prion induction by the short-lived, stress-induced protein Lsb2 is regulated by ubiquitination and association with the actin cytoskeleton.

J. McNally, T. Karpova, K. Wilkinson, 2011, Molecular cell.

Mutations in ADE3 reduce the efficiency of the omnipotent suppressor sup45-2

S. Liebman, Jae Mahn Song, 1989, Current Genetics.

A new colour assay for [URE3] prion in a genetic background used to score for the [PSI+] prion

S. Liebman, Vidhu Mathur, J. Y. Hong, 2011, Yeast.

Prion Formation and Polyglutamine Aggregation Are Controlled by Two Classes of Genes

S. Lindquist, J. Tyedmers, S. Liebman, 2011, PLoS genetics.

Heterologous cross-seeding mimics cross-species prion conversion in a yeast model

S. Liebman, Namitha Vishveshwara, 2009, BMC Biology.

Dependence and independence of [PSI+] and [PIN+]: a two‐prion system in yeast?

S. Liebman, I. Derkatch, M. E. Bradley, 2000, The EMBO journal.

The PNM2 mutation in the prion protein domain of SUP35 has distinct effects on different variants of the [PSI+] prion in yeast

P. Zhou, S. Liebman, I. Derkatch, 1999, Current Genetics.

Variant-specific prion interactions

S. Liebman, J. Sharma, 2013, Cellular logistics.

The RAD52 gene is not required for the function of the DEL1 mutator gene in Saccharomyces cerevisiae

S. Liebman, K. Downs, 2004, Molecular and General Genetics MGG.

Ty elements are involved in the formation of deletions in DEL1 strains of saccharomyces cerevisiae

S. Liebman, P. Shalit, S. Picologlou, 1981, Cell.

Analysis of amyloid aggregates using agarose gel electrophoresis.

S. Liebman, Sviatoslav N. Bagriantsev, V. Kushnirov, 2006, Methods in enzymology.

Alterations in ribosomal protein RPS28 can diversely affect translational accuracy in Saccharomyces cerevisiae.

S. Liebman, R. Anthony, 1995, Genetics.

Overexpression of a conserved HSP40 chaperone reduces toxicity of several neurodegenerative disease proteins

S. Verma, S. Liebman, F. Arslan, 2018, Prion.

Analysis of the effect of radiation repair mutations on the DEL1 mutator region of Saccharomyces cerevisiae

S. Liebman, K. Downs, A. E. Szwast, 1983, Current Genetics.

Yeast amber suppressors corresponding to tRNA3Leu genes.

C. Reed, J. Stewart, F. Sherman, 1984, Journal of molecular biology.

Leucine insertion caused by a yeast amber suppressor.

J. Stewart, F. Sherman, S. Liebman, 1977, Journal of molecular biology.

Serine substitutions caused by an ochre suppressor in yeast.

J. Stewart, F. Sherman, S. Liebman, 1975, Journal of molecular biology.

A deletion map of cyc1 mutants and its correspondence to mutationally altered iso-1-cytochromes c of yeast.

J. Stewart, F. Sherman, S. Liebman, 1975, Genetics.

Isolation and characterization of amber suppressors in yeast.

J. Stewart, F. Sherman, S. Liebman, 1976, Genetics.

Isolation of omnipotent suppressors in an [eta+] yeast strain.

S. Liebman, J. All-Robyn, N. Brown, 1990, Genetics.

A founder mutation in FLNC is likely a major cause of idiopathic dilated cardiomyopathy in Ashkenazi Jews.

S. Liebman, Haley Palaganas, H. Kobany, 2020, International journal of cardiology.

The translational function of nucleotide C1054 in the small subunit rRNA is conserved throughout evolution: genetic evidence in yeast.

Y. Chernoff, S. Liebman, G. Newnam, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Does Saccharomyces need an organized nucleolus?

J. Warner, C. Nierras, S. Liebman, 1997, Chromosoma.

Nonsense suppressors of Saccharomyces cerevisiae can be generated by mutation of the tyrosine tRNA anticodon

P. Piper, J. Zeuthen, F. Sherman, 1976, Nature.

Deletions extending from a single Ty1 element in Saccharomyces cerevisiae

S. Liebman, K. Downs, G Brennan, 1985, Molecular and cellular biology.

A mutator affecting the region of the iso-1-cytochrome c gene in yeast.

F. Sherman, S. Liebman, A. Singh, 1979, Genetics.

Progress toward an ultimate proof of the prion hypothesis

S. Liebman, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Prions: The shape of a species barrier

S. Liebman, 2001, Nature.

Respiration Enhances TDP-43 Toxicity, but TDP-43 Retains Some Toxicity in the Absence of Respiration.

S. Liebman, Sei-Kyoung Park, Sangeun Park, 2018, Journal of molecular biology.

TDP-43 is more toxic in respiring than in non-respiring cells, but respiration is not absolutely required for TDP-43 toxicity

S. Liebman, Sei-Kyoung Park, Sangeun Park, 2018, bioRxiv.

Genetic and environmental factors affecting the de novo appearance of the [PSI+] prion in Saccharomyces cerevisiae.

Y. Chernoff, S. Liebman, I. Derkatch, 1997, Genetics.

Response from Chernoff et al.

S. Lindquist, Y. Chernoff, S. Liebman, 1995 .

Allosuppressors that enhance the efficiency of omnipotent suppressors in Saccharomyces cerevisiae.

S. Liebman, J. M. Song, J. Song, 1987, Genetics.

Tyrosine substitutions resulting from suppression of amber mutants of iso-1-cytochrome c in yeast.

J. Stewart, F. Sherman, S. Liebman, 1973, Journal of molecular biology.

"Prion-proof" for [PIN+]: infection with in vitro-made amyloid aggregates of Rnq1p-(132-405) induces [PIN+].

S. Liebman, B. Patel, 2007, Journal of molecular biology.

Chimeric rRNAs containing the GTPase centers of the developmentally regulated ribosomal rRNAs of Plasmodium falciparum are functionally distinct.

S W Liebman, T. McCutchan, S. Liebman, 1998, RNA.

Host genes that affect the target-site distribution of the yeast retrotransposon Ty1.

C. Burck, S. Liebman, H. Huang, 1999, Genetics.

Yeast Ty1 Retrotransposition Is Stimulated by a Synergistic Interaction between Mutations in Chromatin Assembly Factor I and Histone Regulatory Proteins

Zhijian Qian, Judith Berman, J. Berman, 1998, Molecular and Cellular Biology.

Prions Affect the Appearance of Other Prions The Story of [PIN+]

S. Liebman, I. Derkatch, M. E. Bradley, 2001, Cell.

DoesSaccharomyces need an organized nucleolus?

C. Nierras, S. Liebman, J. R. Warner, 2006, Chromosoma.

The yeast translational allosuppressor, SAL6: a new member of the PP1-like phosphatase family with a long serine-rich N-terminal extension.

S. Liebman, G. Newnam, A. Vincent, 1994, Genetics.

Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies

T. Iwatsubo, T. Hashimoto, S. Liebman, 2019, PLoS genetics.

A yeast model of calcium-responsive transactivator protein (CREST) proteinopathy shows that PBP1/ATXN2 modifies CREST aggregation and toxicity

S. Liebman, Sei-Kyoung Park, Sangeun Park, 2018, bioRxiv.

Heterologous Aggregates Promote De Novo Prion Appearance via More than One Mechanism

S. Liebman, F. Arslan, Sei-Kyoung Park, 2015, PLoS genetics.

[PSI+] prion variant establishment in yeast

S. Liebman, J. Sharma, 2012, Molecular microbiology.

Prions in Yeast

Y. Chernoff, S. Liebman, 2012, Genetics.

Translational suppressors and antisuppressors alter the efficiency of the Ty1 programmed translational frameshift.

P. Farabaugh, Y. Chernoff, C. Burck, 1999, RNA.

of the Ty 1 programmed translational frameshift Translational suppressors and antisuppressors alter the efficiency service

P. Farabaugh, Y. Chernoff, C. Burck, 1999 .

A Genetic Tool to Track Protein Aggregates and Control Prion Inheritance

Ahmad S. Khalil, Christopher P. Mancuso, Gregory A. Newby, 2017, Cell.

Prion-Prion Interactions

S. Liebman, I. Derkatch, 2007, Prion.

Role of the chaperone protein Hsp104 in propagation of the yeast prion-like factor [psi+].

S W Liebman, S. Lindquist, Y. Chernoff, 1995, Science.

An engineered nonsense URA3 allele provides a versatile system to detect the presence, absence and appearance of the [PSI+] prion in Saccharomyces cerevisiae

S. Liebman, Kathryn T. Kirkland, A. Manogaran, 2006, Yeast.

Propagation of the [PIN+] prion by fragments of Rnq1 fused to GFP

S. Liebman, Y. Vitrenko, Stephen I. Stone, 2007, Current Genetics.

Tumor suppressor protein p53 expressed in yeast can remain diffuse, form a prion, or form unstable liquid-like droplets

S. Liebman, Sei-Kyoung Park, Sangeun Park, 2020, iScience.

The same configuration of Ty elements promotes different types and frequencies of rearrangements in different yeast strains

S. Liebman, P. Kovarik, M. Dicig, 1988, Molecular and General Genetics MGG.

Analysis of yeast retrotransposon Ty insertions at the CAN1 locus.

S. Liebman, C. Wilke, N. Brown, 1989, Genetics.

Sequence and functional similarity between a yeast ribosomal protein and the Escherichia coli S5 ram protein

E. Otaka, S. Liebman, J. All-Robyn, 1990, Molecular and cellular biology.

Biochemical and genetic methods for characterization of [PIN+] prions in yeast.

S. Liebman, I. Derkatch, Sviatoslav N. Bagriantsev, 2006, Methods.

The relationship between visible intracellular aggregates that appear after overexpression of Sup35 and the yeast prion‐like elements [PSI+] and [PIN+]

S. Liebman, P. Zhou, I. Derkatch, 2001, Molecular microbiology.

An accuracy center in the ribosome conserved over 2 billion years.

S. Liebman, L. Alksne, R. Anthony, 1993, Proceedings of the National Academy of Sciences of the United States of America.

Analyzing the Birth and Propagation of Two Distinct Prions, [PSI+] and [Het-s]y, in Yeast

Yidi Sun, S. Liebman, V. Taneja, 2010, Molecular biology of the cell.

Prion‐promoted phosphorylation of heterologous amyloid is coupled with ubiquitin‐proteasome system inhibition and toxicity

S. Liebman, D. Stone, Zi Yang, 2014, Molecular microbiology.

Sequestration of essential proteins causes prion associated toxicity in yeast

S. Liebman, M. E. Bradley, Namitha Vishveshwara, 2009, Molecular microbiology.

The yeast global transcriptional co-repressor protein Cyc8 can propagate as a prion

S. Liebman, J. Gavin-Smyth, B. Patel, 2009, Nature Cell Biology.

Destabilizing interactions among [PSI(+)] and [PIN(+)] yeast prion variants.

S. Liebman, M. E. Bradley, 2003, Genetics.

Genesis and variability of [PSI] prion factors in Saccharomyces cerevisiae.

Y. Chernoff, S. Liebman, I. Derkatch, 1996, Genetics.

Elongation factor EF-1 alpha gene dosage alters translational fidelity in Saccharomyces cerevisiae

M. Tuite, C. Grant, S. Liebman, 1989, Molecular and cellular biology.

Structural clues to prion mysteries

S. Liebman, 2005, Nature Structural &Molecular Biology.

Tracking the elusive prion.

J. Mastrianni, S. Liebman, 2005, Trends in molecular medicine.

Effects of Q/N-rich, polyQ, and non-polyQ amyloids on the de novo formation of the [PSI+] prion in yeast and aggregation of Sup35 in vitro.

S. Lindquist, S. M. Uptain, T. Outeiro, 2004, Proceedings of the National Academy of Sciences of the United States of America.

Interactions among prions and prion “strains” in yeast

R. Wickner, S. Liebman, H. Edskes, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Yeast ribosomal protein L24 affects the kinetics of protein synthesis and ribosomal protein L39 improves translational accuracy, while mutants lacking both remain viable.

S. Liebman, I. Derkatch, J. Dresios, 2000, Biochemistry.

The accuracy center of a eukaryotic ribosome.

Y. Chernoff, S. Liebman, R. Liu, 1995, Biochemistry and cell biology = Biochimie et biologie cellulaire.

A non-Mendelian factor, [eta+], causes lethality of yeast omnipotent-suppressor strains

S. Liebman, J. All-Robyn, 1984, Current Genetics.

Omnipotent Suppressors, Allosuppressors and Antisuppressors of Yeast

S. Liebman, Jae Mahn Song, J. All-Robyn, 1988 .

Isolation and properties of an antisuppressor in Saccharomyces cerevisiae specific for an omnipotent suppressor

S. Liebman, M. Cavenagh, L. Bennett, 1980, Journal of bacteriology.

Characterization of novel rad6/ubc2 ubiquitin-conjugating enzyme mutants in yeast

A. Mesecar, S. Liebman, Gail M. Freiberg, 2000, Current Genetics.

11 Protein Synthesis and Translational Control in Saccharomyces cerevisiae

A. Hinnebusch, S. Liebman, 1991 .

The yeast omnipotent suppressor SUP46 encodes a ribosomal protein which is a functional and structural homolog of the Escherichia coli S4 ram protein.

S. Liebman, A. Vincent, 1992, Genetics.

Specificity of Prion Assembly in Vivo

S. Liebman, Sviatoslav N. Bagriantsev, 2004, Journal of Biological Chemistry.

Mutations in helix 27 of the yeast Saccharomyces cerevisiae 18S rRNA affect the function of the decoding center of the ribosome.

A. Mankin, C. Li, S. Liebman, 2000, RNA.

Genetic interaction between yeast Saccharomyces cerevisiae release factors and the decoding region of 18 S rRNA.

A. Mesecar, Y. Chernoff, S. Liebman, 2001, Journal of molecular biology.

Variant-specific [PSI+] infection is transmitted by Sup35 polymers within [PSI+] aggregates with heterogeneous protein composition.

J. Richmond, S. Liebman, Elena O. Gracheva, 2008, Molecular biology of the cell.

A non-Q/N-rich prion domain of a foreign prion, [Het-s], can propagate as a prion in yeast.

M. Maddelein, S. Liebman, S. Saupe, 2007, Molecular cell.

Overexpression of the SUP 45 gene encoding a Sup 35 p-binding protein inhibits the induction of the de novo appearance of the [ PSI 1 ] prion

S. Liebman, I. Derkatch, M. E. Bradley, 1998 .

Comment on Billant et al. p53, A Victim of the Prion Fashion. Cancers 2021, 13, 269

S. Liebman, I. Derkatch, Sei-Kyoung Park, 2023, Cancers.

Heterologous Gln/Asn-Rich Proteins Impede the Propagation of Yeast Prions by Altering Chaperone Availability

S. Liebman, I. Derkatch, J. Y. Hong, 2013, PLoS genetics.

Localization of HET-S to the Cell Periphery, Not to [Het-s] Aggregates, Is Associated with [Het-s]–HET-S Toxicity

R. Riek, S. Liebman, S. Saupe, 2011, Molecular and Cellular Biology.

Development and validation of a yeast high-throughput screen for inhibitors of Aβ42 oligomerization

A. Mesecar, L. Jungbauer, M. LaDu, 2011, Disease Models & Mechanisms.

Prions and amyloids--an overview.

S. Liebman, 2011, Seminars in cell & developmental biology.

Most, but not all, yeast strains in the deletion library contain the [PIN+] prion

Robert J. D. Reid, R. Rothstein, S. Liebman, 2009, Yeast.

Ssa1 overexpression and [PIN(+)] variants cure [PSI(+)] by dilution of aggregates.

S. Liebman, J. Y. Hong, Vidhu K. Mathur, 2009, Journal of molecular biology.

Development and validation of a yeast high-throughput screen for inhibitors of A b 42 oligomerization

A. Mesecar, L. Jungbauer, M. LaDu, 2022 .

The role of Hsp104 in stress tolerance and [PSI+] propagation in Saccharomyces cerevisiae.

S. Lindquist, A. Kowal, Y. Chernoff, 1995, Cold Spring Harbor symposia on quantitative biology.

Visualization of Aggregation of the Rnq1 Prion Domain and Cross-seeding Interactions with Sup35NM*

J. Richmond, S. Liebman, Elena O. Gracheva, 2007, Journal of Biological Chemistry.

Modulation of Aβ42 low-n oligomerization using a novel yeast reporter system

S. Liebman, Sviatoslav N. Bagriantsev, Sviatoslav Bagriantsev, 2006, BMC Biology.

TDP-43 Toxicity in Yeast Is Associated with a Reduction in Autophagy, and Deletions of TIP41 and PBP1 Counteract These Effects

S. Liebman, Sei-Kyoung Park, Sangeun Park, 2022, Viruses.

Mitotic recombination within the centromere of a yeast chromosome.

L. Symington, T. Petes, S. Liebman, 1988, Science.

Inhibition of Aβ42 oligomerization in yeast by a PICALM ortholog and certain FDA approved drugs

K. Ratia, S. Liebman, M. Valencik, 2016, Microbial cell.

7 Prions of Yeast and Filamentous Fungi: [URE3], [ PSI + ], [ PIN + ], and [Het-s]

R. Wickner, S. Liebman, S. Saupe, 2004 .

Recombination associated with yeast retrotransposons

S. Liebman, S. Picologlou, 1988 .

Inhibition of growth by amber suppressors in yeast.

S W Liebman, F Sherman, F. Sherman, 1976, Genetics.

Guanidine reduces stop codon read‐through caused by missense mutations in SUP35 or SUP45

S. Liebman, Sviatoslav N. Bagriantsev, M. E. Bradley, 2003, Yeast.

The yeast non‐Mendelian factor [ETA+] is a variant of [PSI+], a prion‐like form of release factor eRF3

S. Lindquist, S. Liebman, I. Derkatch, 1999, The EMBO journal.

The DEL1 mutator gene in Saccharomyces cerevisiae does not act in trans

S. Liebman, S. Picologlou, 2004, Current Genetics.