K. McElwee

发表

Comparison of Alopecia areata in Human and Nonhuman Mammalian Species

J. Sundberg, D. Tobin, J. Bystryn, 1998, Pathobiology.

Third International Research Workshop on Alopecia Areata.

K. McElwee, 1999, The Journal of investigative dermatology.

Hair follicles and their role in skin health

J. Shapiro, K. McElwee, Mei Yu, 2006 .

Experimental and early investigational drugs for androgenetic alopecia

K. McElwee, Hongwei Guo, W. Gao, 2017, Expert opinion on investigational drugs.

CXCR3/ligands are significantly involved in the tumorigenesis of basal cell carcinomas.

J. Shapiro, K. McElwee, Mei Yu, 2010, The American journal of pathology.

Tumorigenesis and Neoplastic Progression CXCR3/Ligands Are Significantly Involved in the Tumorigenesis of Basal Cell Carcinomas

J. Shapiro, K. McElwee, Mei Yu, 2010 .

Abnormal Interactions between Perifollicular Mast Cells and CD8+ T-Cells May Contribute to the Pathogenesis of Alopecia Areata

R. Paus, K. McElwee, M. Bertolini, 2014, PloS one.

Melanocyte and gonad activity as potential severity modifying factors in C3H/HeJ mouse alopecia areata

J. Sundberg, K. McElwee, K. Silva, 2001, Experimental dermatology.

Rat Immune System

K. McElwee, B. Steiniger, 2003 .

An update on diagnosis and treatment of female pattern hair loss

J. Shapiro, K. McElwee, T. Mubki, 2013 .

Diagnosis and management of primary cicatricial alopecia: part I.

J. Shapiro, Wen-yu Wu, K. McElwee, 2008, Skinmed.

Alopecia areata update: part II. Treatment.

J. Shapiro, K. McElwee, A. Alkhalifah, 2010, Journal of the American Academy of Dermatology.

Alopecia Areata is Associated with Increased Expression of Heart Disease Biomarker Cardiac Troponin I.

J. Shapiro, K. McElwee, E. Wang, 2018, Acta dermato-venereologica.

Development of Autoimmune Hair Loss Disease Alopecia Areata Is Associated with Cardiac Dysfunction in C3H/HeJ Mice

J. Shapiro, K. McElwee, D. Granville, 2013, PloS one.

Spontaneous and Experimental Skin-Graft-Transfer Mouse Models of Alopecia Areata

J. Sundberg, K. McElwee, L. King, 2003 .

Sequential cyclic changes of hair roots revealed by dermoscopy demonstrate a progressive mechanism of diffuse alopecia areata over time

K. McElwee, X. Zhang, Y. Ye, 2018, Experimental dermatology.

Biology of the hair follicle and mechanisms of nonscarring and scarring alopecia.

K. McElwee, L. Santos, T. Chu, 2015, Seminars in cutaneous medicine and surgery.

Disordered Hair Follicle

K. McElwee, E. Wang, 2013 .

Hair physiology and its disorders

R. Sinclair, K. McElwee, 2008 .

Interleukin‐6 cytokine family member oncostatin M is a hair‐follicle‐expressed factor with hair growth inhibitory properties

J. Shapiro, K. McElwee, Mei Yu, 2007, Experimental dermatology.

Biology of the Hair Follicle

K. McElwee, U. Blume-Peytavi, A. Vogt, 2008 .

Gene array profiling and immunomodulation studies define a cell-mediated immune response underlying the pathogenesis of alopecia areata in a mouse model and humans.

J. Sundberg, M. Byrne, K. McElwee, 2002, The Journal of investigative dermatology.

In vivo depletion of CD8+ T cells restores hair growth in the DEBR model for alopecia areata

K. McElwee, R. Oliver, E. Spiers, 1996, The British journal of dermatology.

Apoptosis resistance in peripheral blood lymphocytes of alopecia areata patients.

M. Zöller, K. McElwee, M. Vitacolonna, 2004, Journal of autoimmunity.

Animal Models for Alopecia Areata: What and Where?

J. Sundberg, L. Su, K. McElwee, 2015, The journal of investigative dermatology. Symposium proceedings.

The C3H/HeJ mouse and DEBR rat models for alopecia areata: review of preclinical drug screening approaches and results

J. Sundberg, K. McElwee, Lloyd E. King Jr., 2008, Experimental dermatology.

Regulatory T cells in autoimmune diseases and their potential.

K. McElwee, P. Freyschmidt‐Paul, R. Hoffmann, 2005, The journal of investigative dermatology. Symposium proceedings.

Transfer of CD8(+) cells induces localized hair loss whereas CD4(+)/CD25(-) cells promote systemic alopecia areata and CD4(+)/CD25(+) cells blockade disease onset in the C3H/HeJ mouse model.

M. Zöller, K. McElwee, M. Vitacolonna, 2005, The Journal of investigative dermatology.

Hair follicle mesenchyme-associated PD-L1 regulates T-cell activation induced apoptosis: a potential mechanism of immune privilege.

J. Shapiro, Lieping Chen, A. Mui, 2014, The Journal of investigative dermatology.

Alopecia areata susceptibility in rodent models.

M. Zöller, K. McElwee, P. Freyschmidt‐Paul, 2003, The journal of investigative dermatology. Symposium proceedings.

Alopecia Areata in C3H/HeJ Mice Involves Leukocyte-mediated Root Sheath Disruption in Advance of Overt Hair Loss

J. Sundberg, K. McElwee, D. Boggess, 2003, Veterinary pathology.

Measuring cortisol and DHEA in fingernails: A pilot study

A. Young, Rubo J. Seo, K. McElwee, 2009, Neuropsychiatric disease and treatment.

Transient CD44 variant isoform expression and reduction in CD4(+)/CD25(+) regulatory T cells in C3H/HeJ mice with alopecia areata.

M. Zöller, K. McElwee, R. Hoffmann, 2002, The Journal of investigative dermatology.

Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts.

J. Sundberg, K. McElwee, D. Boggess, 1998, The Journal of investigative dermatology.

Increased expression of TLR7 and TLR9 in alopecia areata

J. Shapiro, Wen-yu Wu, K. McElwee, 2019, Experimental dermatology.

Hair Follicle Dermal Sheath Derived Cells Improve Islet Allograft Survival without Systemic Immunosuppression

J. Shapiro, G. Warnock, K. McElwee, 2015, Journal of immunology research.

Allergy to dust mites may contribute to early onset and severity of alopecia areata

H. Cao, K. McElwee, Y. Ye, 2015, Clinical and experimental dermatology.

Endogenous retinoids in the pathogenesis of alopecia areata

J. Sundberg, J. Szatkiewicz, F. J. Duncan, 2012, The Journal of investigative dermatology.

Promising therapies for treating and/or preventing androgenic alopecia.

J. Shapiro, K. McElwee, Jerry Shapiro, 2012, Skin therapy letter.

Serum level of IL‐4 predicts response to topical immunotherapy with diphenylcyclopropenone in alopecia areata

K. McElwee, X. Zhang, S. Caulloo, 2018, Experimental dermatology.

Interferon-gamma-deficient mice are resistant to the development of alopecia areata.

J. Sundberg, M. Zöller, K. McElwee, 2006, The British journal of dermatology.

Resistance to alopecia areata in C3H/HeJ mice is associated with increased expression of regulatory cytokines and a failure to recruit CD4+ and CD8+ cells.

J. Sundberg, M. Zöller, K. McElwee, 2002, The Journal of investigative dermatology.

Hair follicles from alopecia areata patients exhibit alterations in immune privilege-associated gene expression in advance of hair loss.

J. Shapiro, Wen-yu Wu, K. McElwee, 2010, The Journal of investigative dermatology.

Spontaneous Rat Model of Alopecia Areata in the Dundee Experimental Bald Rat (DEBR)

K. McElwee, 2003 .

Spontaneous alopecia areata-like hair loss in one congenic and seven inbred laboratory mouse strains.

J. Sundberg, K. McElwee, D. Boggess, 1999, The journal of investigative dermatology. Symposium proceedings.

Fas-deficient C3.MRL-Tnfrsf6(lpr) mice and Fas ligand-deficient C3H/HeJ-Tnfsf6(gld) mice are relatively resistant to the induction of alopecia areata by grafting of alopecia areata-affected skin from C3H/HeJ mice.

J. Sundberg, R. Happle, K. McElwee, 2003, The journal of investigative dermatology. Symposium proceedings.

Topical FK506: a potent immunotherapy for alopecia areata? Studies using the Dundee experimental bald rat model

K. McElwee, R. Oliver, R. Trachy, 1997, The British journal of dermatology.

Reduced expression of interleukin-2 decreases the frequency of alopecia areata onset in C3H/HeJ mice.

J. Sundberg, A. Kopp-Schneider, M. Zöller, 2005, The Journal of investigative dermatology.

The progressive state, in contrast to the stable or regressive state of alopecia areata, is reflected in peripheral blood mononuclear cells

M. Zöller, K. McElwee, M. Vitacolonna, 2004, Experimental dermatology.

Macrophage-stimulating protein promotes hair growth ex vivo and induces anagen from telogen stage hair follicles in vivo.

K. McElwee, R. Hoffmann, A. Huth, 2004, The Journal of investigative dermatology.

Aggravated TSLP-Induced Atopic Dermatitis in Mice Lacking Dicer in Adult Skin Keratinocytes

J. Sundberg, K. McElwee, L. King, 2010 .

Hair follicle immune privilege and its collapse in alopecia areata

R. Paus, K. McElwee, M. Bertolini, 2020, Experimental dermatology.

What causes alopecia areata?

J. Sundberg, S. Inui, A. Tosti, 2013, Experimental dermatology.

Major locus on mouse chromosome 17 and minor locus on chromosome 9 are linked with alopecia areata in C3H/HeJ mice.

J. Sundberg, Renhua Li, G. Cox, 2003, The Journal of investigative dermatology.

What Can We Learn from Animal Models of Alopecia areata?

J. Shapiro, K. McElwee, Sung-Wook Park, 2005, Dermatology.

Treatment of alopecia areata in C3H/HeJ mice with the topical immunosuppressant FK506 (Tacrolimus).

J. Sundberg, R. Happle, K. McElwee, 2001, European journal of dermatology : EJD.

The DEBR rat, alopecia areata and autoantibodies to the hair follicle

K. McElwee, R. Oliver, P. Pickett, 1996, The British journal of dermatology.

Treatment of alopecia areata in the DEBR model using Cyclosporin A lipid vesicles.

A. Fahr, K. McElwee, A Fahr, 2004, European journal of dermatology : EJD.

Cultured peribulbar dermal sheath cells can induce hair follicle development and contribute to the dermal sheath and dermal papilla.

K. McElwee, R. Hoffmann, A. Huth, 2003, The Journal of investigative dermatology.

Allergy promotes alopecia areata in a subset of patients

K. McElwee, Xingqi Zhang, 2019, Experimental dermatology.

Alopecia areata − animal models

K. McElwee, R. Hoffmann, 2002, Clinical and experimental dermatology.

Current and potential agents for the treatment of alopecia areata.

J. Sundberg, R. Happle, K. McElwee, 2001, Current pharmaceutical design.

Alopecia areata update: part I. Clinical picture, histopathology, and pathogenesis.

J. Shapiro, K. McElwee, A. Alkhalifah, 2010, Journal of the American Academy of Dermatology.

Dietary soy oil content and soy‐derived phytoestrogen genistein increase resistance to alopecia areata onset in C3H/HeJ mice

K. McElwee, P. Freyschmidt‐Paul, R. Hoffmann, 2003, Experimental dermatology.

Early stage alopecia areata is associated with inflammation in the upper dermis and damage to the hair follicle infundibulum

K. McElwee, Bin Zhang, Mei Yu, 2013, The Australasian journal of dermatology.

Etiopathogenesis of alopecia areata: Why do our patients get it?

K. McElwee, E. Wang, 2011, Dermatologic therapy.

Etiology of cicatricial alopecias: a basic science point of view

K. McElwee, 2008, Dermatologic therapy.

Alopecia areata: pathogenesis and potential for therapy

Wei Lu, Kevin McElwee, Jerry Shapiro, 2006, Expert Reviews in Molecular Medicine.

A “hair‐raising” history of alopecia areata

K. McElwee, D. Broadley, 2020, Experimental dermatology.

The pathogenesis of alopecia areata in rodent models.

J. Sundberg, K. McElwee, P. Freyschmidt‐Paul, 2003, The journal of investigative dermatology. Symposium proceedings.

Successful treatment of alopecia areata-like hair loss with the contact sensitizer squaric acid dibutylester (SADBE) in C3H/HeJ mice.

J. Sundberg, R. Happle, K. McElwee, 1999, The Journal of investigative dermatology.

The role of lymphocytes in the development and treatment of alopecia areata

J. Shapiro, K. McElwee, Yabin Cheng, 2015, Expert review of clinical immunology.

Identification of Autoantigen Epitopes in Alopecia Areata.

J. Shapiro, K. McElwee, Xiaojie Wang, 2016, The Journal of investigative dermatology.

Alopecia areata: an autoimmune disease?

J. Sundberg, D. Tobin, J. Bystryn, 1999, Experimental dermatology.

The basic science of hair biology: what are the causal mechanisms for the disordered hair follicle?

K. McElwee, Mei Yu, Gigi Leung, 2013, Dermatologic clinics.

Development of alopecia areata is associated with higher central and peripheral hypothalamic-pituitary-adrenal tone in the skin graft induced C3H/HeJ mouse model.

J. Shapiro, J. Weinberg, K. McElwee, 2009, The Journal of investigative dermatology.

Chronic delayed‐type hypersensitivity reaction as a means to treat alopecia areata

M. Zöller, K. McElwee, R. Hoffmann, 2004, Clinical and experimental immunology.

Murine cytomegalovirus is not associated with alopecia areata in C3H/HeJ mice.

J. Sundberg, K. McElwee, D. Boggess, 1998, The Journal of investigative dermatology.

Common skin conditions and disorders Hair physiology and its disorders

R. Sinclair, K. McElwee, 2008 .

Lichen planopilaris and pseudopelade of Brocq involve distinct disease associated gene expression patterns by microarray.

Robert H. Bell, M. Martinka, J. Shapiro, 2010, Journal of dermatological science.

Ratite oils promote keratinocyte cell growth and inhibit leukocyte activation.

D. Bennett, K. Cheng, K. McElwee, 2015, Poultry science.

Fibroblast cell-based therapy prevents induction of alopecia areata in an experimental model

A. Ghahary, R. Jalili, K. McElwee, 2018, Cell transplantation.

Examining the Relationship between Alopecia Areata, Androgenetic Alopecia, and Emotional Intelligence

J. Shapiro, R. Bar-On, K. McElwee, 2013, Journal of cutaneous medicine and surgery.

Somatostatin expression in human hair follicles and its potential role in immune privilege.

J. Shapiro, K. McElwee, Mei Yu, 2013, The Journal of investigative dermatology.

Deficiency in Nucleotide Excision Repair Family Gene Activity, Especially ERCC3, Is Associated with Non-Pigmented Hair Fiber Growth

J. Shapiro, K. McElwee, Mei Yu, 2012, PloS one.

Immunotherapy of melanoma: Present options and future promises

A. Rotte, Madhuri Bhandaru, Youwen Zhou, 2015, Cancer and Metastasis Reviews.

Alopecia areata: treatment of today and tomorrow.

R. Happle, K. McElwee, P. Freyschmidt‐Paul, 2003, The journal of investigative dermatology. Symposium proceedings.

Notch signaling is significantly suppressed in basal cell carcinomas and activation induces basal cell carcinoma cell apoptosis

J. Shapiro, K. McElwee, Mei Yu, 2017, Molecular medicine reports.

Benefit of different concentrations of intralesional triamcinolone acetonide in alopecia areata: An intrasubject pilot study.

J. Shapiro, K. McElwee, T. Chu, 2015, Journal of the American Academy of Dermatology.

Loss of tumor suppressors KAI1 and p27 identifies a unique subgroup of primary melanoma patients with poor prognosis

M. Martinka, A. Rotte, Qi Wang, 2015, Oncotarget.

Reduced expression of SRY-box containing gene 17 correlates with an unfavorable melanoma patient survival.

Gang Li, Z. Dong, Guohong Zhang, 2014, Oncology reports.

eIF4E is an adverse prognostic marker of melanoma patient survival by increasing melanoma cell invasion.

M. Martinka, C. Ong, K. McElwee, 2015, The Journal of investigative dermatology.

Diagnosis and management of primary cicatricial alopecia: part II.

J. Shapiro, Wen-yu Wu, K. McElwee, 2008, Skinmed.

Alopecia areata versus juvenile alopecia in C3H/HeJ mice: tools to dissect the role of inflammation in focal alopecia.

J. Sundberg, K. McElwee, D. Boggess, 1999, Experimental dermatology.

Integrin β6-deficient mice show enhanced keratinocyte proliferation and retarded hair follicle regression after depilation.

H. Larjava, L. Häkkinen, K. McElwee, 2012, The Journal of investigative dermatology.

Prognostic Significance of Nuclear Phospho-ATM Expression in Melanoma

M. Martinka, A. Rotte, Madhuri Bhandaru, 2015, PloS one.

Increased expression of neuropilin 1 in melanoma progression and its prognostic significance in patients with melanoma

Gang Li, Z. Dong, Guohong Zhang, 2015, Molecular medicine reports.

Stage-specific prognostic biomarkers in melanoma

M. Martinka, A. Rotte, Guohong Zhang, 2015, Oncotarget.

Superficial, nodular, and morpheiform basal-cell carcinomas exhibit distinct gene expression profiles.

J. Shapiro, K. McElwee, Mei Yu, 2008, The Journal of investigative dermatology.

High LIFr expression stimulates melanoma cell migration and is associated with unfavorable prognosis in melanoma

M. Martinka, K. McElwee, Yabin Cheng, 2015 .

Immunotherapy of melanoma: Present options and future promises

A. Rotte, Madhuri Bhandaru, Youwen Zhou, 2015, Cancer and Metastasis Reviews.

Autologous Cell Therapy for Aged Human Skin: A Randomized, Placebo-Controlled, Phase-I Study

A. Marini, S. Grether-Beck, J. Krutmann, 2019, Skin Pharmacology and Physiology.

Interferon‐γ‐deficient mice are resistant to the development of alopecia areata

M. Zöller, K. McElwee, M. Vitacolonna, 2006 .

Nonsurgical Induction of Alopecia Areata in C3H/HeJ Mice via Adoptive Transfer of Cultured Lymphoid Cells.

K. McElwee, E. Wang, 2020, Methods in molecular biology.

Transfer of Alopecia Areata to C3H/HeJ Mice Using Cultured Lymph Node-Derived Cells.

J. Shapiro, A. Ghahary, R. Jalili, 2015, The Journal of investigative dermatology.

Frontal fibrosing alopecia: a retrospective clinical review of 62 patients with treatment outcome and long‐term follow‐up

J. Shapiro, K. McElwee, T. Mubki, 2014, International journal of dermatology.

Two sisters, two different hair shaft abnormalities

J. Shapiro, K. McElwee, N. Otberg, 2009, The British journal of dermatology.

Assessment of hair density and caliber in Caucasian and Asian female subjects with female pattern hair loss by using the Folliscope.

J. Shapiro, K. McElwee, A. Monselise, 2012, Journal of the American Academy of Dermatology.

Hypothesis Testing: CTLA4 Co-stimulatory Pathways Critical in the Pathogenesis of Human and Mouse Alopecia Areata

J. Sundberg, K. McElwee, L. King, 2011, The Journal of investigative dermatology.

A combination of p300 and Braf expression in the diagnosis and prognosis of melanoma

M. Martinka, Gang Li, A. Rotte, 2014, BMC Cancer.

Allergen desensitization reduces the severity of relapsed alopecia areata in dust‐mite allergic patients

K. McElwee, Jian Yang, Y. Ye, 2023, Experimental dermatology.

Signalling by senescent melanocytes hyperactivates hair growth

Kevin H. Tran, A. Mortazavi, A. Ganesan, 2023, Nature.

Growth factor concentrations in platelet‐rich plasma for androgenetic alopecia: An intra‐subject, randomized, blinded, placebo‐controlled, pilot study

J. Shapiro, K. McElwee, Gigi Leung, 2020, Experimental dermatology.

Genetic susceptibility and severity of alopecia areata in human and animal models.

R. Happle, K. McElwee, A. Ziegler, 2001, European journal of dermatology : EJD.

Interleukin-10-deficient mice are less susceptible to the induction of alopecia areata.

J. Sundberg, R. Happle, M. Zöller, 2002, The Journal of investigative dermatology.

Hair follicle autoantibodies in DEBR rat sera.

K. McElwee, R. Oliver, P. Pickett, 1995, The Journal of investigative dermatology.

New developments in hair research

A. Tosti, K. McElwee, 2020, Experimental dermatology.

The functional relevance of the type 1 cytokines IFN-gamma and IL-2 in alopecia areata of C3H/HeJ mice.

J. Sundberg, R. Happle, K. McElwee, 2005, The journal of investigative dermatology. Symposium proceedings.

Alopecia areata in humans and other mammalian species.

J. Sundberg, K. McElwee, R. Oliver, 1995, Journal of Investigative Dermatology.

CXCR3 ligands promote expression of functional indoleamine 2,3‐dioxygenase in basal cell carcinoma keratinocytes

J. Shapiro, A. Ghahary, R. Jalili, 2011, The British journal of dermatology.

Hair follicle mesenchyme-associated PD-L1 regulates T-cell activation induced apoptosis: a potential mechanism of immune privilege.

J. Shapiro, Lieping Chen, A. Mui, 2014, The Journal of investigative dermatology.

Identification of Autoantigen Epitopes in Alopecia Areata.

J. Shapiro, K. McElwee, Xiaojie Wang, 2016, The Journal of investigative dermatology.

Growth factors in early hair follicle morphogenesis.

K. McElwee, R. Hoffmann, 2000, European journal of dermatology : EJD.

eIF4E is an adverse prognostic marker of melanoma patient survival by increasing melanoma cell invasion.

M. Martinka, C. Ong, K. McElwee, 2015, The Journal of investigative dermatology.

Label-free identification and characterization of murine hair follicle stem cells located in thin tissue sections with Raman micro-spectroscopy.

D. McLean, H. Lui, H. Zeng, 2014, The Analyst.

Induction of Alopecia Areata in C3H/HeJ Mice via Cultured Cell Transfer

K. McElwee, E. Wang, 2014 .

Measuring cortisol and DHEA in fingernails: A pilot study

A. Young, Rubo J. Seo, K. McElwee, 2009, Neuropsychiatric disease and treatment.

Partial restoration of hair growth in the DEBR model for alopecia areata after in vivo depletion of CD4+ T cells

K. McElwee, McELWEE, Spiers, 1999, The British journal of dermatology.

Innovative strategies for the discovery of new drugs against alopecia areata: taking aim at the immune system.

K. McElwee, Siyuan Chen, Hong-Wei Guo, 2024, Expert opinion on drug discovery.