A. K. Cardozo

发表

Proteomics Analysis of Cytokine-induced Dysfunction and Death in Insulin-producing INS-1E Cells

K. Lage, L. Arckens, Y. Moreau, 2007, Molecular & Cellular Proteomics.

Analysis of Exonic Mutations Leading to Exon Skipping in Patients with Pyruvate Dehydrogenase E1α Deficiency

W. Lissens, I. Liebaers, A. K. Cardozo, 2000, Pediatric Research.

Global profiling of double stranded RNA- and IFN-γ-induced genes in rat pancreatic beta cells

T. Ørntoft, M. Kruhøffer, D. Eizirik, 2003, Diabetologia.

Is ARE/poly(U)-binding factor 1 (AUF1) a new player in cytokine-mediated beta cell apoptosis?

A. K. Cardozo, E. Vanzela, E. C. Vanzela, 2012, Diabetologia.

Interferon-γ potentiates endoplasmic reticulum stress-induced death by reducing pancreatic beta cell defence mechanisms

D. Eizirik, A. K. Cardozo, D. Eizirik, 2006, Diabetologia.

C/EBP homologous protein contributes to cytokine-induced pro-inflammatory responses and apoptosis in β-cells

J. Haefliger, P. Marchetti, D. Eizirik, 2012, Cell Death and Differentiation.

Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis

M. Fukaya, A. K. Cardozo, L. F. Terra, 2018, Cell Death & Disease.

Plasma Membrane Ca2+-ATPase Overexpression Depletes Both Mitochondrial and Endoplasmic Reticulum Ca2+ Stores and Triggers Apoptosis in Insulin-secreting BRIN-BD11 Cells*

M. Brini, E. Carafoli, A. Herchuelz, 2010, The Journal of Biological Chemistry.

Inhibition of cytokine-induced NF-kappaB activation by adenovirus-mediated expression of a NF-kappaB super-repressor prevents beta-cell apoptosis.

D. Eizirik, C. Jobin, H. Heimberg, 2001, Diabetes.

The non-canonical NF-κB pathway and its contribution to β-cell failure in diabetes.

F. Ortis, A. K. Cardozo, K. Meyerovich, 2018, Journal of molecular endocrinology.

Inhibition of nuclear factor-kappaB or Bax prevents endoplasmic reticulum stress- but not nitric oxide-mediated apoptosis in INS-1E cells.

N. Billestrup, T. Mandrup-Poulsen, A. K. Cardozo, 2009, Endocrinology.

Mcl-1 downregulation by pro-inflammatory cytokines and palmitate is an early event contributing to β-cell apoptosis

D. Eizirik, J. Vanderwinden, A. K. Cardozo, 2011, Cell Death and Differentiation.

PTPN 2 , a candidate gene for type 1 diabetes , modulates interferon-gamma-induced pancreatic beta-cell apoptosis

M. Bugliani, P. Marchetti, D. Eizirik, 2009 .

PTPN2, a Candidate Gene for Type 1 Diabetes, Modulates Interferon-γ–Induced Pancreatic β-Cell Apoptosis

M. Bugliani, P. Marchetti, D. Eizirik, 2009, Diabetes.

1,25-Dihydroxyvitamin D3 modulates expression of chemokines and cytokines in pancreatic islets: implications for prevention of diabetes in nonobese diabetic mice.

C. Mathieu, D. Eizirik, R. Bouillon, 2005, Endocrinology.

A20 Inhibits β-Cell Apoptosis by Multiple Mechanisms and Predicts Residual β-Cell Function in Type 1 Diabetes.

F. Pociot, H. Mortensen, L. Catrysse, 2016, Molecular endocrinology.

Heterozygous Inactivation of the Na/Ca Exchanger Increases Glucose-Induced Insulin Release, β-Cell Proliferation, and Mass

S. Schurmans, M. Manto, E. Montanya, 2011, Diabetes.

The non-canonical NF-κB pathway is induced by cytokines in pancreatic beta cells and contributes to cell death and proinflammatory responses in vitro

F. Ortis, M. Fukaya, A. K. Cardozo, 2016, Diabetologia.

Deletion of C/EBP homologous protein (Chop) in C57Bl/6 mice dissociates obesity from insulin resistance

C. Mathieu, D. Eizirik, M. Cnop, 2012, Diabetologia.

Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes.

A. K. Cardozo, D. Eizirik, P. Pirot, 2008, Arquivos brasileiros de endocrinologia e metabologia.

Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus.

Dongbo Liu, A. K. Cardozo, D. Eizirik, 2002, Endocrinology.

IL-1beta and IFN-gamma induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice.

C. Mathieu, P. Proost, C. Gysemans, 2003, Diabetologia.

A20 deficiency sensitizes pancreatic beta cells to cytokine-induced apoptosis in vitro but does not influence type 1 diabetes development in vivo

L. Catrysse, G. van Loo, R. Beyaert, 2015, Cell Death and Disease.

Inhibition of Cytokine-Induced NF- B Activation by Adenovirus-Mediated Expression of a NF- B Super-Repressor Prevents -Cell Apoptosis

C. Jobin, H. Heimberg, A. K. Cardozo, 2001 .

Sustained production of spliced X-box binding protein 1 (XBP1) induces pancreatic beta cell dysfunction and apoptosis

D. Eizirik, F. Ortis, S. Lenzen, 2010, Diabetologia.

Nova1 or Bim Deficiency in Pancreatic β-Cells Does Not Alter Multiple Low-Dose Streptozotocin-Induced Diabetes and Diet-Induced Obesity in Mice

P. Xiao, A. K. Cardozo, E. N. Gurzov, 2022, Nutrients.

Cell Loss during Pseudoislet Formation Hampers Profound Improvements in Islet Lentiviral Transduction Efficacy for Transplantation Purposes

C. Mathieu, D. Eizirik, C. Gysemans, 2007, Cell transplantation.

SP-D and CC-16 Pneumoproteins' Kinetics and Their Predictive Role During SARS-CoV-2 Infection

P. van de Borne, F. Mascart, V. del Marmol, 2022, Frontiers in Medicine.

Chemerin plasma levels are increased in COVID-19 patients and are an independent risk factor of mortality

P. van de Borne, F. Mascart, C. Decaestecker, 2022, Frontiers in Immunology.

The role for endoplasmic reticulum stress in diabetes mellitus.

D. Eizirik, M. Cnop, A. K. Cardozo, 2008, Endocrine reviews.

Prolactin protects against cytokine-induced beta-cell death by NFκB and JNK inhibition.

D. Eizirik, F. Ortis, A. Fujita, 2018, Journal of molecular endocrinology.

Heterozygous inactivation of plasma membrane Ca2+-ATPase in mice increases glucose-induced insulin release and beta cell proliferation, mass and viability

J. Mast, A. Herchuelz, A. K. Cardozo, 2015, Diabetologia.

Na+/Ca2+ Exchanger a Druggable Target to Promote β-Cell Proliferation and Function

A. Herchuelz, A. K. Cardozo, R. Regazzi, 2018, Journal of the Endocrine Society.

NF-κB-inducing kinase (NIK) is activated in pancreatic β-cells but does not contribute to the development of diabetes

L. Marselli, E. Dejardin, G. van Loo, 2022, Cell Death & Disease.

Na/Ca Exchanger a Druggable Target to Promoteb-Cell ProliferationandFunction

A. Herchuelz, A. K. Cardozo, R. Regazzi, 2018 .

Free fatty acids and cytokines induce pancreatic beta-cell apoptosis by different mechanisms: role of nuclear factor-kappaB and endoplasmic reticulum stress.

D. Eizirik, M. Cnop, A. K. Cardozo, 2004, Endocrinology.

Cytokines downregulate the sarcoendoplasmic reticulum pump Ca2+ ATPase 2b and deplete endoplasmic reticulum Ca2+, leading to induction of endoplasmic reticulum stress in pancreatic beta-cells.

F. Ortis, T. Mandrup-Poulsen, A. Herchuelz, 2005, Diabetes.

Free Fatty Acids and Cytokines Induce Pancreatic β-Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor-κB and Endoplasmic Reticulum Stress

M. Cnop, A. K. Cardozo, D. Eizirik, 2004 .

Signalling danger: endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation

D. Eizirik, A. K. Cardozo, D. Eizirik, 2013, Diabetologia.

Initiation and execution of lipotoxic ER stress in pancreatic β-cells

Tsonwin Hai, G. Rutter, P. Marchetti, 2008, Journal of Cell Science.

Endoplasmic reticulum stress and the unfolded protein response in pancreatic islet inflammation.

F. Ortis, A. K. Cardozo, F. Allagnat, 2016, Journal of molecular endocrinology.

JunB protects β-cells from lipotoxicity via the XBP1–AKT pathway

M. Bugliani, P. Marchetti, D. Eizirik, 2014, Cell Death and Differentiation.

Use of Microarray Analysis to Unveil Transcription Factor and Gene Networks Contributing to β Cell Dysfunction and Apoptosis

Joanne Rasschaert, D. Eizirik, A. K. Cardozo, 2003, Annals of the New York Academy of Sciences.

IL-1β and IFN-γ induce the expression of diverse chemokines and IL-15 in human and rat pancreatic islet cells, and in islets from pre-diabetic NOD mice

C. Mathieu, D. Eizirik, P. Proost, 2003, Diabetologia.

Inhibition of RIPK1 kinase does not affect diabetes development: β-Cells survive RIPK1 activation

M. Bertrand, E. H. Gilglioni, A. K. Cardozo, 2023, Molecular metabolism.

SKAP2, a Candidate Gene for Type 1 Diabetes, Regulates β-Cell Apoptosis and Glycemic Control in Newly Diagnosed Patients

F. Pociot, H. Mortensen, S. Kaur, 2020, Diabetes.

Proteomic analysis of cytokine-induced dysfunction and death in ins-1E cells: New insights into the pathways involved

Etienne Waelkens, C. Mathieu, D. Eizirik, 2007 .

Transcriptional Regulation of the Endoplasmic Reticulum Stress Gene Chop in Pancreatic Insulin-Producing Cells

F. Ortis, M. Cnop, L. Hendershot, 2007, Diabetes.

Molecular regulation of monocyte chemoattractant protein-1 expression in pancreatic beta-cells.

A. K. Cardozo, B. Kutlu, D. Eizirik, 2003, Diabetes.

Connexin36 contributes to INS-1E cells survival through modulation of cytokine-induced oxidative stress, ER stress and AMPK activity

J. Haefliger, P. Meda, A. K. Cardozo, 2013, Cell Death and Differentiation.

A Comprehensive Analysis of Cytokine-induced and Nuclear Factor-κB-dependent Genes in Primary Rat Pancreatic β-Cells*

M. Kruhøffer, H. Heimberg, A. K. Cardozo, 2001, The Journal of Biological Chemistry.

Identification of novel cytokine-induced genes in pancreatic beta-cells by high-density oligonucleotide arrays.

M. Kruhøffer, D. Eizirik, T. Orntoft, 2001, Diabetes.

Discovery of gene networks regulating cytokine-induced dysfunction and apoptosis in insulin-producing INS-1 cells.

Mogens Kruhøffer, T. Ørntoft, M. Kruhøffer, 2003, Diabetes.

Free Fatty Acids and Cytokines Induce Pancreatic (cid:1) -Cell Apoptosis by Different Mechanisms: Role of Nuclear Factor- (cid:2) B and Endoplasmic Reticulum Stress

D. Eizirik, M. Cnop, A. K. Cardozo, 2004 .

Cytokine-induced proapoptotic gene expression in insulin-producing cells is related to rapid, sustained, and nonoscillatory nuclear factor-kappaB activation.

F. Ortis, T. Mandrup-Poulsen, A. K. Cardozo, 2006, Molecular endocrinology.

Dysfunctional autophagy following exposure to pro-inflammatory cytokines contributes to pancreatic β-cell apoptosis

M. Fukaya, A. K. Cardozo, L. F. Terra, 2018, Cell Death & Disease.

Selective Inhibition of Eukaryotic Translation Initiation Factor 2α Dephosphorylation Potentiates Fatty Acid-induced Endoplasmic Reticulum Stress and Causes Pancreatic β-Cell Dysfunction and Apoptosis*

Junying Yuan, Michael Boyce, Junying Yuan, 2006, Journal of Biological Chemistry.

Signaling by IL-1β+IFN-γ and ER stress converge on DP5/Hrk activation: a novel mechanism for pancreatic β-cell apoptosis

D. Eizirik, F. Ortis, M. Li, 2009, Cell Death and Differentiation.

Cell-permeable peptides induce dose- and length-dependent cytotoxic effects.

J. Beckmann, O. Poirot, D. Eizirik, 2007, Biochimica et biophysica acta.

MCL-1 Is a Key Antiapoptotic Protein in Human and Rodent Pancreatic β-Cells

A. Strasser, P. Marchetti, D. Eizirik, 2017, Diabetes.

Exposure to the Viral By-Product dsRNA or Coxsackievirus B5 Triggers Pancreatic Beta Cell Apoptosis via a Bim / Mcl-1 Imbalance

D. Eizirik, M. Colli, M. Roivainen, 2011, PLoS pathogens.

Double-Stranded RNA Cooperates with Interferon-γ and IL-1β to Induce Both Chemokine Expression and Nuclear Factor-κB-Dependent Apoptosis in Pancreatic β-Cells: Potential Mechanisms for Viral-Induced Insulitis and β-Cell Death in Type 1 Diabetes Mellitus.

Dongbo Liu, A. K. Cardozo, D. Eizirik, 2002, Endocrinology.

Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs

T. Ørntoft, D. Eizirik, N. Magnusson, 2007, Diabetologia.

Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis

Decio L. Eizirik, Torben F. Ørntoft, Nils E. Magnusson, 2005, BMC Bioinformatics.

High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFκB

A. K. Cardozo, J. Henquin, D. Eizirik, 2005, Diabetologia.

High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NF kappa B (vol 48, pg 496, 2005)

A. K. Cardozo, J. Henquin, D. Eizirik, 2005 .

Global profiling of double stranded RNA- and IFN-gamma-induced genes in rat pancreatic beta cells.

T. Ørntoft, M. Kruhøffer, A. K. Cardozo, 2003, Diabetologia.

The Cytokine Interleukin-1β Reduces the Docking and Fusion of Insulin Granules in Pancreatic β-Cells, Preferentially Decreasing the First Phase of Exocytosis*

A. K. Cardozo, D. Eizirik, S. Nagamatsu, 2004, Journal of Biological Chemistry.

High glucose and hydrogen peroxide increase c-Myc and haeme-oxygenase 1 mRNA levels in rat pancreatic islets without activating NFκB

A. K. Cardozo, J. Henquin, D. Eizirik, 2005, Diabetologia.

Prolactin protects against cytokine-induced beta-cell death by NFκB and JNK inhibition.

D. Eizirik, F. Ortis, A. Boschero, 2018, Journal of molecular endocrinology.

MCL-1 Is a Key Antiapoptotic Protein in Human and Rodent Pancreatic β-Cells

A. Strasser, P. Marchetti, D. Eizirik, 2017, Diabetes.