Chao Huang

发表

NOGEA: Network-Oriented Gene Entropy Approach for Dissecting Disease Comorbidity and Drug Repositioning

Zhenzhong Wang, W. Xiao, Yan Li, 2020, bioRxiv.

A Novel Chemometric Method for the Prediction of Human Oral Bioavailability

Hua Yu, Xue Xu, Yonghua Wang, 2012, International journal of molecular sciences.

Systematic understanding the mechanisms of vitiligo pathogenesis and its treatment by Qubaibabuqi formula.

Yonghua Wang, Yingxue Fu, Xuetong Chen, 2016, Journal of ethnopharmacology.

Systems Pharmacology Uncovers the Multiple Mechanisms of Xijiao Dihuang Decoction for the Treatment of Viral Hemorrhagic Fever

Yonghua Wang, Yingxue Fu, Zongsuo Liang, 2016, Evidence-based complementary and alternative medicine : eCAM.

Deciphering the multicomponent synergy mechanism from a systems pharmacology perspective: Application to Gualou Xiebai Decoction for coronary heart disease

Zhenzhong Wang, W. Xiao, Yonghua Wang, 2018, Journal of Functional Foods.

Systems pharmacology exploration of botanic drug pairs reveals the mechanism for treating different diseases

Jinan Wang, Wei Zhou, Yonghua Wang, 2016, Scientific Reports.

A novel systems pharmacology platform to dissect action mechanisms of traditional Chinese medicines for bovine viral diarrhea disease.

Yan Li, Yonghua Wang, Xuetong Chen, 2016, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

Large-scale cross-species chemogenomic platform proposes a new drug discovery strategy of veterinary drug from herbal medicines

Yan Li, Yonghua Wang, Xuetong Chen, 2017, PloS one.

New strategy for drug discovery by large-scale association analysis of molecular networks of different species

Bo Zhang, Yan Li, Yonghua Wang, 2016, Scientific Reports.

System-level multi-target drug discovery from natural products with applications to cardiovascular diseases

Jinan Wang, Yonghua Wang, Chao Huang, 2014, Molecular Diversity.

Systems pharmacology uncovers serotonergic pathway mediated psychotherapeutic effects of Lonicerae Japonicae Flos

Zhenzhong Wang, W. Xiao, Yonghua Wang, 2019, Journal of Functional Foods.

Systems-Pharmacology Dissection of Traditional Chinese Medicine Compound Saffron Formula Reveals Multi-scale Treatment Strategy for Cardiovascular Diseases

Yonghua Wang, Yingxue Fu, Xuetong Chen, 2016, Scientific Reports.

Licorice Extracts Inhibits growth of Non-Small Cell Lung Cancer by Down-Regulating CDK4-Cyclin D1 Complex and Increasing CD8+ T Cell Infiltration

Yonghua Wang, W. Xiao, Chao Huang, 2021 .

Methylglyoxal modification of TrkB promotes synaptic plasticity and enhances resilience to chronic stress

Zhenzhong Wang, W. Xiao, Yan Li, 2018, bioRxiv.

Methylglyoxal modification of TrkB promotes synaptic plasticity

Zhenzhong Wang, Yan Li, Yinfeng Yang, 2018 .

Gating TrkB switch by methylglyoxal enables GLO1 as a target for depression

W. Xiao, Yan Li, Yinfeng Yang, 2018 .

Systems Pharmacology Dissecting Holistic Medicine for Treatment of Complex Diseases: An Example Using Cardiocerebrovascular Diseases Treated by TCM

Yonghua Wang, Chunli Zheng, Xuetong Chen, 2015, Evidence-based complementary and alternative medicine : eCAM.

CancerHSP: anticancer herbs database of systems pharmacology

Yuan Wang, Yonghua Wang, Shuo Gao, 2015, Scientific Reports.

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

Wei Zhou, Peng Li, Ling Yang, 2014, Journal of Cheminformatics.

Large-scale Direct Targeting for Drug Repositioning and Discovery

Yan Li, Yuan Wang, Ziyin Wu, 2015, Scientific Reports.

Systems pharmacology in drug discovery and therapeutic insight for herbal medicines

Chao Huang, Ling Yang, Yan Li, 2014, Briefings Bioinform..

Deciphering the combination principles of Traditional Chinese Medicine from a systems pharmacology perspective based on Ma-huang Decoction.

Yonghua Wang, Chunli Zheng, Chao Huang, 2013, Journal of ethnopharmacology.

A systematic identification of multiple toxin-target interactions based on chemical, genomic and toxicological data.

Yan Li, Wei Zhou, Chao Huang, 2013, Toxicology.

Systems pharmacology: a combination strategy for improving efficacy of PD-1/PD-L1 blockade

Yonghua Wang, Chunli Zheng, Chao Huang, 2021, Briefings Bioinform..

The total flavonoids of Hippophae rhamnoides stimulate recruitment of CD8+ T cells into the tumor microenvironment promoting cancer immune control

Yuanyuan Hao, Xuetong Chen, Chao Huang, 2021, Phytomedicine Plus.

Weak-binding molecules are not drugs?—toward a systematic strategy for finding effective weak-binding drugs

Wei Xiao, Chao Huang, Jinan Wang, 2016, Briefings Bioinform..

Systems pharmacology-based approach for dissecting the addition and subtraction theory of traditional Chinese medicine: An example using Xiao-Chaihu-Decoction and Da-Chaihu-Decoction

Chao Huang, Yonghua Wang, Yingxue Fu, 2014, Comput. Biol. Medicine.

Systems pharmacology dissection of Epimedium targeting tumor microenvironment to enhance cytotoxic T lymphocyte responses in lung cancer

Zhenzhong Wang, W. Xiao, Yonghua Wang, 2021, Aging.

A novel systems pharmacology model for herbal medicine injection: a case using reduning injection

Wei Zhou, Yonghua Wang, Yan Li, 2014, BMC Complementary and Alternative Medicine.

Insights from systems pharmacology into cardiovascular drug discovery and therapy

Peng Li, Chao Huang, Ling Yang, 2014, BMC Systems Biology.

Predicting the herbal medicine triggering innate anti-tumor immunity from a system pharmacology perspective.

Yonghua Wang, Chao Huang, Chunli Zheng, 2021, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

Systems pharmacology analysis of synergy of TCM: an example using saffron formula

Yonghua Wang, Meng Jiang, Yingxue Fu, 2018, Scientific Reports.

Platycodon grandiflorum Triggers Antitumor Immunity by Restricting PD-1 Expression of CD8+ T Cells in Local Tumor Microenvironment

Chao Huang, Chunli Zheng, Jinglin Zhu, 2022, Frontiers in Pharmacology.

Large-scale exploration and analysis of drug combinations

Jianxin Chen, Wei Zhou, Peng Li, 2015, Bioinform..

Pred-binding: large-scale protein–ligand binding affinity prediction

Yonghua Wang, Shuo Gao, Mohamed Shahen, 2016, Journal of enzyme inhibition and medicinal chemistry.

Licorice extract inhibits growth of non-small cell lung cancer by down-regulating CDK4-Cyclin D1 complex and increasing CD8+ T cell infiltration

Yonghua Wang, Chao Huang, Chunli Zheng, 2021, Cancer cell international.

Systems-Mapping of Herbal Effects on Complex Diseases Using the Network-Perturbation Signatures

Chao Huang, Shuo Gao, Aiping Lu, 2018, Front. Pharmacol..

Blocking LTB4 signaling-mediated TAMs recruitment by Rhizoma Coptidis sensitizes lung cancer to immunotherapy.

Chao Huang, Chunli Zheng, Jinglin Zhu, 2023, Phytomedicine : international journal of phytotherapy and phytopharmacology.

NOGEA: A Network-oriented Gene Entropy Approach for Dissecting Disease Comorbidity and Drug Repositioning

Zhenzhong Wang, W. Xiao, Yan Li, 2021, Genom. Proteom. Bioinform..

Pred-binding: large-scale protein–ligand binding affinity prediction

W. Tao, Yonghua Wang, Chao Huang, 2016, Journal of enzyme inhibition and medicinal chemistry.