J. Tocker

发表

A disease module in the interactome explains disease heterogeneity, drug response and captures novel pathways and genes in asthma.

A. Barabasi, E. Silverman, Radu Dobrin, 2015, Human molecular genetics.

Cutting Edge: Interleukin 17 Signals through a Heteromeric Receptor Complex

J. Derry, M. Wolfson, J. Peschon, 2006, The Journal of Immunology.

Il-25-induced Activities Il-17rb and Il-17ra in Mediating Identification of Functional Roles for Both

E. Rickel, J. Tocker, D. Kugler, 2022 .

Identification of Functional Roles for Both IL-17RB and IL-17RA in Mediating IL-25-Induced Activities

E. Rickel, J. Tocker, D. Kugler, 2008, The Journal of Immunology.

Cutting Edge: Identification of a Pre-Ligand Assembly Domain (PLAD) and Ligand Binding Site in the IL-17 Receptor1

A. Maitra, T. Jin, S. Gaffen, 2007, The Journal of Immunology.

Binding Site in the IL-17 Receptor Assembly Domain ( PLAD ) and Ligand Cutting Edge : Identification of a Pre-Ligand

A. Maitra, T. Jin, S. Gaffen, 2007 .

IL-25 elicits a multi-potent progenitor cell population that promotes Th2 cytokine responses

R. Kastelein, A. Bhandoola, J. Perrigoue, 2010, Nature.

An antibody to IP-10 is a potent antagonist of cell migration in vitro and in vivo and does not affect disease in several animal models of inflammation

S. Steavenson, D. Brankow, T. Juan, 2009, Autoimmunity.

Ro 25-1553: a novel, long-acting vasoactive intestinal peptide agonist. Part II: Effect on in vitro and in vivo models of pulmonary anaphylaxis.

R. Garippa, J. Tocker, D. Bolin, 1994, The Journal of pharmacology and experimental therapeutics.

The TNF Family Molecules LIGHT and Lymphotoxin αβ Induce a Distinct Steroid-Resistant Inflammatory Phenotype in Human Lung Epithelial Cells

M. Croft, L. Madge, J. Tocker, 2015, The Journal of Immunology.

No defect in T-cell priming, secondary response, or tolerance induction in response to inhaled antigens in Fms-like tyrosine kinase 3 ligand-deficient mice.

J. Tocker, T. Walzer, David A. Swart, 2005, The Journal of allergy and clinical immunology.

Phospholipase A2-induced pulmonary and hemodynamic responses in the guinea pig. Effects of enzyme inhibitors and mediators antagonists.

J. Tocker, S. Durham, A. Welton, 1990, The American review of respiratory disease.

Effect of interleukin-1 receptor antagonist on antigen-induced pulmonary responses in guinea pigs.

J. Tocker, W. Selig, William M. Selig, 1992, European journal of pharmacology.

Airway eosinophils from actively sensitized guinea pigs exhibit enhanced superoxide anion release in response to antigen challenge.

J. Tocker, F. Cerasoli, W. Selig, 1991, American journal of respiratory cell and molecular biology.

Reversal of Thymic Stromal Lymphopoietin-Induced Airway Inflammation through Inhibition of Th2 Responses1

S. Ziegler, M. Headley, J. Tocker, 2008, The Journal of Immunology.

Pharmacological evidence for tumor necrosis factor as a mediator of allergic inflammation in the airways.

J. Tocker, M. Wasserman, S. Tannu, 1996, The Journal of pharmacology and experimental therapeutics.

Inflammation through Inhibition of Th 2 Lymphopoietin-Induced Airway Reversal of Thymic Stromal

S. Ziegler, M. Headley, J. Tocker, 2008 .

Food allergy and gastrointestinal disease Prevention of food allergy development and suppression of established food allergy by neutralization of thymic stromal lymphopoietin , IL-25 , and IL-33

F. Finkelman, M. Khodoun, J. Tocker, 2017 .

Paradoxical role of programmed death‐1 ligand 2 in Th2 immune responses in vitro and in a mouse asthma model in vivo

T. Horan, D. Fitzpatrick, A. Welcher, 2004, European journal of immunology.

Stem cell mobilization with G-CSF induces type 17 differentiation and promotes scleroderma.

M. Smyth, Y. Iwakura, G. Hill, 2010, Blood.

Heteromeric Receptor Complex Cutting Edge : Interleukin 17 Signals through Peschon

J. Derry, M. Wolfson, J. Peschon, 2006 .

Studies of the Combination of Ro 24–5913, a Peptidoleukotriene Antagonist, and Ro 24–4736, a PAF Antagonist, in Guinea pig and Rat Models of Lung Inflammation

J. Tocker, M. Wasserman, P. Newbold, 1994, Annals of the New York Academy of Sciences.

SOCS3 regulates graft-versus-host disease.

W. Alexander, A. Roberts, G. Hill, 2010, Blood.

Dominance of Δ5-sterols in eight species of the cactaceae

J. Adler, J. Tocker, Thomas A. Salt, 1987 .

Expanding the drug discovery space with predicted metabolite–target interactions

James R. Brown, E. Berg, Andrea Nuzzo, 2021, Communications biology.

TNFSF14 (LIGHT) Exhibits Inflammatory Activities in Lung Fibroblasts Complementary to IL-13 and TGF-β

M. Croft, L. Madge, J. Tocker, 2018, Front. Immunol..

SOCS 3 regulates graft-versus-host disease

W. Alexander, A. Roberts, G. Hill, 2010 .

Interleukin-23 is critical for full-blown expression of a non-autoimmune destructive arthritis and regulates interleukin-17A and RORγt in γδ T cells

E. Lubberts, J. Tocker, F. Cornelissen, 2009, Arthritis research & therapy.

Interferon-gamma regulates susceptibility to collagen-induced arthritis through suppression of interleukin-17.

K. Elkon, J. Tocker, C. Chu, 2007, Arthritis and rheumatism.

Distinct functional motifs within the IL-17 receptor regulate signal transduction and target gene expression

A. Maitra, S. Gaffen, K. Mossman, 2007, Proceedings of the National Academy of Sciences.

IL-17RA Signaling in Airway Inflammation and Bronchial Hyperreactivity in Allergic Asthma.

K. Misura, E. Rickel, J. Sullivan, 2015, American journal of respiratory cell and molecular biology.

Vagal stimulation augments pulmonary anaphylaxis in the guinea pig lung.

S. B. Gertner, J. Tocker, A. Welton, 1995, American journal of respiratory and critical care medicine.

Pharmacologic modulation of antigen-induced pulmonary responses in the perfused guinea pig lung.

J. Tocker, F. Cerasoli, S. Tannu, 1993, The American review of respiratory disease.

Novel Therapeutics

M. Horner, J. Tocker, C. Banfield, 2014, Inflammation Research.

138 Distinct Functional Motifs Within the IL-17 Receptor Regulate Signal Transduction and Target Gene Expression

A. Maitra, S. Gaffen, K. Mossman, 2007 .

A14 INJECTED TIMP-3 PROTECTS CARTILAGE IN A RAT MENISCAL TEAR MODEL

B. Castner, R. Black, A. Bendele, 2006 .

IL-17RA Signaling in Airway Inflammation and Bronchial Hyperreactivity in Allergic Asthma.

K. Misura, E. Rickel, J. Sullivan, 2015, American journal of respiratory cell and molecular biology.