N. Yigit

发表

Charting extracellular transcriptomes in The Human Biofluid RNA Atlas

G. Schroth, L. Simon, S. Kuersten, 2019, bioRxiv.

Correction: Human fetal neuroblast and neuroblastoma transcriptome analysis confirms neuroblast origin and highlights neuroblastoma candidate genes

R. Stallings, F. Speleman, J. Vandesompele, 2007, Genome Biology.

Chromosome 3p Microsatellite Allelotyping in Neuroblastoma: A Report on the Technical Hurdles

F. Speleman, J. Vandesompele, E. Stanbridge, 2009, Cancer investigation.

Aberrant methylation of candidate tumor suppressor genes in neuroblastoma.

F. Speleman, J. Vandesompele, A. De Paepe, 2009, Cancer letters.

High resolution tiling‐path BAC array deletion mapping suggests commonly involved 3p21‐p22 tumor suppressor genes in neuroblastoma and more frequent tumors

F. Speleman, B. Menten, J. Vandesompele, 2007, International journal of cancer.

Comprehensive benchmarking of single cell RNA sequencing technologies for characterizing cellular perturbation

Y. Saeys, F. Speleman, J. Vandesompele, 2020, bioRxiv.

SMARTer single cell total RNA sequencing

K. Livak, J. Kjems, F. Speleman, 2018, bioRxiv.

Prognostic and Therapeutic Implications of Circulating Androgen Receptor Gene Copy Number in Prostate Cancer Patients Using Droplet Digital Polymerase Chain Reaction

J. Vandesompele, O. Thas, N. Lumen, 2017, Clinical genitourinary cancer.

EVI1 is consistently expressed as principal transcript in common and rare recurrent 3q26 rearrangements

F. Speleman, J. Vandesompele, A. Hagemeijer, 2006, Genes, chromosomes & cancer.

Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma

F. Speleman, J. Vandesompele, N. Yigit, 2017, Oncotarget.

mTOR inhibition enhances delivery and activity of antisense oligonucleotides in uveal melanoma cells

S. Eyckerman, P. Mestdagh, K. Raemdonck, 2021, bioRxiv.

Novel cryptic chromosomal rearrangements in childhood acute lymphoblastic leukemia detected by multiple color fluorescent in situ hybridization.

F. Speleman, J. Philippé, A. De Paepe, 2005, Haematologica.

The von Hippel‐Lindau tumor suppressor gene expression level has prognostic value in neuroblastoma

F. Speleman, J. Vandesompele, A. De Paepe, 2006, International journal of cancer.

Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes

Pavel Sumazin, F. Speleman, J. Vandesompele, 2019, Scientific Reports.

PAX5/IGH rearrangement is a recurrent finding in a subset of aggressive B‐NHL with complex chromosomal rearrangements

F. Speleman, P. de Paepe, C. de Wolf‐Peeters, 2005, Genes, chromosomes & cancer.

Imperfect protection: NEPA at 35 years.

Frank Speleman, Anne De Paepe, Jo Vandesompele, 2004, Genome Biology.

MISpheroID: a knowledgebase and transparency tool for minimum information in spheroid identity

John C. Dawson, G. Castellani, J. Vandesompele, 2021, Nature Methods.

Small-molecule MDM2 antagonists as a new therapy concept for neuroblastoma.

F. Speleman, J. Vandesompele, J. Philippé, 2006, Cancer research.

EVI1 overexpression in t(3;17) positive myeloid malignancies results from juxtaposition of EVI1 to the MSI2 locus at 17q22

F. Speleman, A. Hagemeijer, C. Bastard, 2008, Haematologica.

Functional Analysis of the p53 Pathway in Neuroblastoma Cells Using the Small-Molecule MDM2 Antagonist Nutlin-3

F. Westermann, F. Speleman, J. Vandesompele, 2011, Molecular Cancer Therapeutics.

Expression analyses identify MLL as a prominent target of 11q23 amplification and support an etiologic role for MLL gain of function in myeloid malignancies.

C. Bloomfield, F. Speleman, J. Vandesompele, 2004, Blood.

Rapid detection of VHL exon deletions using real-time quantitative PCR

F. Speleman, J. Vandesompele, K. Claes, 2005, Laboratory Investigation.

Real-time qPCR as a tool for evaluating RNAi-mediated gene silencing

F. Speleman, J. Vandesompele, J. Marine, 2008 .

RNA pre-amplification enables large-scale RT-qPCR gene-expression studies on limiting sample amounts

F. Speleman, J. Vandesompele, A. De Paepe, 2009, BMC Research Notes.

Unveiling the C1000TM Thermal Cycler’s Protocol Autowriter ProteOnTM XPR36 Protein Interaction Array System Named Product of the Year Optimizing Sample and Bead Volumes for Low-Abundance Protein Enrichment Obtaining Pure Native Protein Via On-Column Cleavage in Less Than One Hour

F. Speleman, J. Vandesompele, A. Paepe, 2008 .

Longitudinal evaluation of serum microRNAs as biomarkers for neuroblastoma burden and therapeutic p53 reactivation

F. Speleman, J. Vandesompele, P. Mestdagh, 2023, NAR cancer.

The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival

J. Vandesompele, J. Marine, S. Eyckerman, 2021, Oncogene.

Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision

Osagie G. Izuogu, P. Flicek, P. Stadler, 2022, bioRxiv.

Antitumor activity of the selective MDM2 antagonist nutlin-3 against chemoresistant neuroblastoma with wild-type p53.

F. Speleman, J. Vandesompele, J. Marine, 2009, Journal of the National Cancer Institute.

Depletion of tRNA-halves enables effective small RNA sequencing of low-input murine serum samples

F. Speleman, J. Vandesompele, P. Mestdagh, 2016, Scientific Reports.

Performance evaluation of RNA purification kits and blood collection tubes in the Extracellular RNA Quality Control (exRNAQC) study

G. Schroth, S. Kuersten, J. Vandesompele, 2022, bioRxiv.

Integrative analysis identifies lincRNAs up- and downstream of neuroblastoma driver genes

Pavel Sumazin, F. Speleman, J. Vandesompele, 2019, Scientific Reports.

myeloid malignancies amplification and support an etiologic role for MLL gain of function in Expression analyses identify MLL as a prominent target of 11q23

J. Vandesompele, A. Hagemeijer, K. Mrózek, 2013 .

HOXA gene cluster rearrangement in a t(7;9)(p15;q34) in a child with MDS.

F. Speleman, A. De Paepe, B. Poppe, 2005, Cancer genetics and cytogenetics.

A 3’-end capture sequencing method for high-throughput targeted gene expression profiling

P. Mestdagh, N. Yigit, E. D. de Bony, 2021, bioRxiv.

Large-scale benchmarking of circRNA detection tools reveals large differences in sensitivity but not in precision

Osagie G. Izuogu, P. Flicek, P. Stadler, 2023, bioRxiv.

Positional and functional mapping of a neuroblastoma differentiation gene on chromosome 11

Frank Speleman, Björn Menten, Wim Waelput, 2005, BMC Genomics.

Correction to: The long non-coding RNA SAMMSON is essential for uveal melanoma cell survival

J. Vandesompele, A. Jochemsen, S. Eyckerman, 2021, bioRxiv.

Dual targeting of MDM2 and BCL2 as a therapeutic strategy in neuroblastoma

F. Speleman, J. Vandesompele, N. Yigit, 2017, OncoTarget.

Beyond Myosin Heavy Chains: Ribosomal Specialization Drives Human Skeletal Muscle Fiber Heterogeneity

J. Vandesompele, A. Deshmukh, W. Derave, 2023, bioRxiv.

RNA pre-amplification enables large-scale RT-qPCR gene-expression studies on limiting sample amounts

F. Speleman, J. Vandesompele, F. Pattyn, 2009 .

Validation of Circular RNAs Using RT‐qPCR After Effective Removal of Linear RNAs by Ribonuclease R

J. Vandesompele, P. Volders, N. Yigit, 2021, Current protocols.

Mammalian Target of Rapamycin Inhibition Enhances Delivery and Activity of Antisense Oligonucleotides in Uveal Melanoma Cells.

S. Eyckerman, P. Mestdagh, K. Raemdonck, 2023, Nucleic acid therapeutics.