K. Burnham

发表

A genetics-led approach defines the drug target landscape of 30 immune-related traits

Hinrich W. H. Göhlmann, David R. Damerell, J. Knight, 2019, Nature Genetics.

XGR software for enhanced interpretation of genomic summary data, illustrated by application to immunological traits

J. Knight, H. Fang, B. Knezevic, 2016, Genome Medicine.

Mortality prediction in sepsis via gene expression analysis: a community approach

Ricardo Henao, S. Kingsmore, R. Henao, 2016, bioRxiv.

A blood atlas of COVID-19 defines hallmarks of disease severity and specificity

Calliope A. Dendrou, I. Pavord, J. Todd, 2021, Cell.

High-throughput mass spectrometry maps the sepsis plasma proteome and differences in response

A. Nesvizhskii, A. Gordon, F. Karpe, 2022, medRxiv.

Constructing custom-made radiotranscriptomic signatures of vascular inflammation from routine CT angiograms: a prospective outcomes validation study in COVID-19

Calliope A. Dendrou, I. Pavord, G. Rodger, 2022, The Lancet Digital Health.

Inflammatory sub-phenotypes in sepsis: relationship to outcomes, treatment effect and transcriptomic sub-phenotypes

M. Shankar-Hari, A. Gordon, K. Burnham, 2022, medRxiv.

Transcriptional reprogramming from innate immune functions to a pro-thrombotic signature by monocytes in COVID-19

Graham W. Taylor, L. Baillon, W. Barclay, 2022, Nature Communications.

Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study

Anna Rautanen, Peter Humburg, J. Knight, 2016, The Lancet. Respiratory medicine.

Classification of patients with sepsis according to blood genomic endotype: a prospective cohort study.

Peter Nürnberg, Marcus J Schultz, Janneke Horn, 2017, The Lancet. Respiratory medicine.

Genomic Insights into Myasthenia Gravis Identify Distinct Immunological Mechanisms in Early and Late Onset Disease

J. Knight, L. Milani, S. Kasela, 2021, Annals of neurology.

COMBATdb: a database for the COVID-19 Multi-Omics Blood ATlas

J. Knight, A. Mentzer, B. Marsden, 2022, Nucleic Acids Res..

Transcriptomic Signatures in Sepsis and a Differential Response to Steroids. From the VANISH Randomized Trial

J. Knight, S. Brett, A. Gordon, 2019, American journal of respiratory and critical care medicine.

An immune dysfunction score for stratification of patients with acute infection based on whole blood gene expression

J. Soar, T. van der Poll, J. Knight, 2022, Science Translational Medicine.

Identification of deleterious neutrophil states and altered granulopoiesis in sepsis

J. Todd, I. Udalova, R. Ferreira, 2022, medRxiv.

A community approach to mortality prediction in sepsis via gene expression analysis

Purvesh Khatri, Larsson Omberg, Marshall Nichols, 2018, Nature Communications.

Shared and Distinct Aspects of the Sepsis Transcriptomic Response to Fecal Peritonitis and Pneumonia

Peter Humburg, J. Knight, P. Humburg, 2017, American journal of respiratory and critical care medicine.

Epstein-Barr virus reactivation in sepsis due to community-acquired pneumonia is associated with increased morbidity and an immunosuppressed host transcriptomic endotype

J. Knight, R. Bowden, M. de Cesare, 2020, Scientific Reports.

A community approach to mortality prediction in sepsis via gene expression analysis

Ricardo Henao, S. Kingsmore, C. Woods, 2018, Nature Communications.

A Transcriptomic Approach to Understand Patient Susceptibility to Pneumonia After Abdominal Surgery

P. Zhang, R. Pearse, A. Gordon, 2023, medRxiv.

Neutrophils and emergency granulopoiesis drive immune suppression and an extreme response endotype during sepsis

J. Todd, A. Mentzer, I. Udalova, 2023, Nature Immunology.

Genomic landscape of the individual host response and outcomes in sepsis: a prospective cohort study

J. Knight, P. Humburg, A. Gordon, 2016, The Lancet. Respiratory medicine.

Sex-Ratio meiotic drive shapes the evolution of the Y chromosome in Drosophila simulans.

M. Chakir, K. Burnham, N. Chaminade, 2019, Molecular biology and evolution.

eQTLs identify regulatory networks and drivers of variation in the individual response to sepsis

N. Soranzo, A. Kapila, E. Cano-Gamez, 2023, bioRxiv.

High-throughput mass spectrometry maps the sepsis plasma proteome and differences in patient response

I. Vendrell, Fengchao Yu, K. Burnham, 2024, Science Translational Medicine.

Patient stratification using plasma cytokines and their regulators in sepsis: relationship to outcomes, treatment effect and leucocyte transcriptomic subphenotypes

M. Shankar-Hari, K. Burnham, P. Hutton, 2024, Thorax.