X. Xia

发表

Functional regulation of BK potassium channels by γ1 auxiliary subunits

C. Lingle, Vivian Gonzalez-Perez, X. Xia, 2014, Proceedings of the National Academy of Sciences.

Mechanism of calcium gating in small-conductance calcium-activated potassium channels

T. Ishii, B. Fakler, J. Adelman, 1998, Nature.

LRRC52 regulates BK channel function and localization in mouse cochlear inner hair cells

C. Lingle, X. Xia, S. Pyott, 2019, Proceedings of the National Academy of Sciences.

Interactions between beta subunits of the KCNMB family and Slo3: Beta4 selectively modulates Slo3 expression and function

C. Lingle, X. Xia, Chengtao Yang, 2018 .

Knockout of the LRRC26 subunit reveals a primary role of LRRC26-containing BK channels in secretory epithelial cells

C. Lingle, J. E. Melvin, Vivian Gonzalez-Perez, 2017, Proceedings of the National Academy of Sciences.

Goblet cell LRRC26 regulates BK channel activation and protects against colitis in mice

Albert C. Chen, Hongzhen Hu, C. Lingle, 2020, Proceedings of the National Academy of Sciences.

Channels Signals by Slo1 BK 2+ Transduction of Voltage and Ca

S. Heinemann, O. McManus, R. Olcese, 2015 .

SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertility

C. Lingle, X. Xia, Chengtao Yang, 2015, Proceedings of the National Academy of Sciences.

Simultaneous knockout of Slo3 and CatSper1 abolishes all alkalization- and voltage-activated current in mouse spermatozoa

D. Clapham, C. Lingle, X. Xia, 2013, The Journal of general physiology.

Interactions between β Subunits of the KCNMB Family and Slo3: β4 Selectively Modulates Slo3 Expression and Function

C. Lingle, X. Xia, Chengtao Yang, 2009, PloS one.

Gating Properties Conferred on Bk Channels by the β3b Auxiliary Subunit in the Absence of Its Nh2- and Cooh Termini

C. Lingle, X. Xia, Xu-hui Zeng, 2001, The Journal of general physiology.

Cloning and expression of a family of inward rectifier potassium channels.

M. Kavanaugh, J. Adelman, M. Pessia, 1994, Receptors & channels.

Inactivation of Bk Channels Mediated by the Nh2 Terminus of the β3b Auxiliary Subunit Involves a Two-Step Mechanism

C. Lingle, X. Xia, Xu-hui Zeng, 2001, The Journal of General Physiology.

Inactivation of BK channels mediated by the NH(2) terminus of the beta3b auxiliary subunit involves a two-step mechanism: possible separation of binding and blockade.

J. Ding, C. Lingle, X. Xia, 2001, The Journal of general physiology.

Cardiac Slo2.1 Is Required for Volatile Anesthetic Stimulation of K+ Transport and Anesthetic Preconditioning

A. Wojtovich, P. Brookes, Yves T. Wang, 2016, Anesthesiology.

LRRC52 (leucine-rich-repeat-containing protein 52), a testis-specific auxiliary subunit of the alkalization-activated Slo3 channel

C. Lingle, X. Xia, Yu Zhou, 2011, Proceedings of the National Academy of Sciences.

Deletion of the Slo3 gene abolishes alkalization-activated K+ current in mouse spermatozoa

C. Lingle, X. Xia, Chengtao Yang, 2011, Proceedings of the National Academy of Sciences.

The functionally relevant site for paxilline inhibition of BK channels

C. Lingle, X. Xia, Yu Zhou, 2019, Proceedings of the National Academy of Sciences.

Block of mouse Slo1 and Slo3 K+ channels by CTX, IbTX, TEA, 4-AP and quinidine

Zhe Zhang, C. Lingle, X. Xia, 2010, Channels.

The Ca2+-activated K+ current of human sperm is mediated by Slo3

W. Bönigk, U. Kaupp, C. Lingle, 2014, eLife.

Calmodulin Regulates Synaptic Plasticity in the Anterior Cingulate Cortex and Behavioral Responses: A Microelectroporation Study in Adult Rodents

M. Zhuo, Jianrong Tang, X. Xia, 2003, The Journal of Neuroscience.

The Ca 2 +-activated K + current of human sperm is mediated by Slo 3

W. Bönigk, U. Kaupp, C. Lingle, 2014 .

Site-directed mutagenesis.

T. Ishii, J. Adelman, J. Maylie, 1998, Methods in enzymology.

Inhibition of Large-Conductance Ca2+-Activated K+ Channels by Nanomolar Concentrations of Ag+

C. Lingle, X. Xia, Yu Zhou, 2010, Molecular Pharmacology.

Inhibition of BK channels by nanomolar concentrations

C. Lingle, X. Xia, Yu Zhou, 2010 .

A Limited Access Compartment between the Pore Domain and Cytosolic Domain of the BK Channel

Zhe Zhang, C. Lingle, X. Xia, 2006, The Journal of Neuroscience.

Sodium‐activated potassium channels moderate excitability in vascular smooth muscle

L. Salkoff, R. Mecham, A. Butler, 2019, The Journal of physiology.

Sodium-activated potassium channels shape peripheral auditory function and activity of the primary auditory neurons in mice

T. Jones, Sarath Vijayakumar, E. Yamoah, 2019, Scientific Reports.

dSLo Interacting Protein 1, a Novel Protein That Interacts with Large-Conductance Calcium-Activated Potassium Channels

J. Adelman, S. Smolik, X. Xia, 1998, The Journal of Neuroscience.

Inward rectifier potassium channels. Cloning, expression and structure-function studies.

J. Adelman, S. Tucker, M. Pessia, 1996, Japanese heart journal.

Knockout of Slo2.2 enhances itch, abolishes KNa current, and increases action potential firing frequency in DRG neurons

C. Lingle, Vivian Gonzalez-Perez, X. Xia, 2015, eLife.

BK channel inhibition by strong extracellular acidification

C. Lingle, X. Xia, Yu Zhou, 2018, bioRxiv.

Cadmium–cysteine coordination in the BK inner pore region and its structural and functional implications

C. Lingle, X. Xia, Yu Zhou, 2015, Proceedings of the National Academy of Sciences.

Multiple regulatory sites in large-conductance calcium-activated potassium channels

C. Lingle, X. Xia, Xu-hui Zeng, 2002, Nature.

Molecular Basis for the Inactivation of Ca2+- and Voltage-Dependent BK Channels in Adrenal Chromaffin Cells and Rat Insulinoma Tumor Cells

C. Lingle, X. Xia, Jiu-ping Ding, 1999, The Journal of Neuroscience.

Consequences of the Stoichiometry of Slo1 α and Auxiliary β Subunits on Functional Properties of Large-Conductance Ca2+-Activated K+Channels

C. Lingle, X. Xia, Jiu-ping Ding, 2002, The Journal of Neuroscience.

Consequences of the Stoichiometry of Slo 1 and Auxiliary Subunits on Functional Properties of Large-Conductance Ca 2-Activated K Channels

C. Lingle, X. Xia, Jiu-ping Ding, 2002 .

Rectification and Rapid Activation at Low Ca2+ of Ca2+-Activated, Voltage-Dependent BK Currents: Consequences of Rapid Inactivation by a Novel β Subunit

C. Lingle, X. Xia, Xu-hui Zeng, 2000, The Journal of Neuroscience.

Two classes of regulatory subunits coassemble in the same BK channel and independently regulate gating

C. Lingle, Vivian Gonzalez-Perez, X. Xia, 2015, Nature Communications.

Glycine311, a determinant of paxilline block in BK channels: a novel bend in the BK S6 helix

C. Lingle, X. Xia, Yu Zhou, 2010, The Journal of general physiology.

Divalent Cation Sensitivity of BK Channel Activation Supports the Existence of Three Distinct Binding Sites

C. Lingle, X. Xia, Xu-hui Zeng, 2005, The Journal of general physiology.

Regulatory γ1 subunits defy symmetry in functional modulation of BK channels

C. Lingle, Vivian Gonzalez-Perez, X. Xia, 2018, Proceedings of the National Academy of Sciences.

Knockout of the BK β2 subunit abolishes inactivation of BK currents in mouse adrenal chromaffin cells and results in slow-wave burst activity

C. Lingle, Vivian Gonzalez-Perez, X. Xia, 2014, The Journal of general physiology.

Inactivation of BK Channels by the NH2 Terminus of the β2 Auxiliary Subunit

C. Lingle, X. Xia, J. Ding, 2003, The Journal of General Physiology.

Inactivation of BK Channels by the NH2 Terminus of the β2 Auxiliary Subunit

J. Ding, C. Lingle, X. Xia, 2003, The Journal of general physiology.

Direct Observation of a Preinactivated, Open State in BK Channels with β2 Subunits

C. Lingle, X. Xia, G. Benzinger, 2006, The Journal of general physiology.

Redox-sensitive extracellular gates formed by auxiliary β subunits of calcium-activated potassium channels

C. Lingle, X. Xia, Xu-hui Zeng, 2003, Nature Structural Biology.

A primary function of goblet cells (GCs) of the intestinal epithelium

Hongzhen Hu, C. Lingle, Vivian Gonzalez-Perez, 2020 .

pH-regulated Slo3 K+ Channels: Properties of Unitary Currents

C. Lingle, X. Xia, Xu-hui Zeng, 2006, The Journal of general physiology.

Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region

C. Lingle, X. Xia, Yu Zhou, 2011, Proceedings of the National Academy of Sciences.

Nav1.3 and FGF14 are primary determinants of the TTX-sensitive sodium current in mouse adrenal chromaffin cells

C. Lingle, X. Xia, P. L. Martinez-Espinosa, 2021, The Journal of general physiology.

A Novel Auxiliary Subunit Critical to BK Channel Function in Caenorhabditis elegans

Bojun Chen, Zhao-Wen Wang, Qian Ge, 2010, The Journal of Neuroscience.

Ligand-Dependent Activation of Slo Family Channels Is Defined by Interchangeable Cytosolic Domains

C. Lingle, X. Xia, Xue Zhang, 2004, The Journal of Neuroscience.

Differences in BK Potassium Channel Properties Bovine Versus Rat Adrenal Chromaffin Cells: Big

M. Zeeman, C. Lingle, D. P. McCobb, 2015 .

Nav1.3 and fibroblast growth factor homologous factor 14 are primary determinants of the TTX-sensitive sodium current in mouse adrenal chromaffin cells

C. Lingle, X. Xia, P. L. Martinez-Espinosa, 2020, bioRxiv.

Species-specific Differences among KCNMB3 BK β3 Auxiliary Subunits: Some β3 N-terminal Variants May Be Primate-specific Subunits

C. Lingle, X. Xia, Xu-hui Zeng, 2008, The Journal of general physiology.

SLO3 auxiliary subunit LRRC52 controls gating of sperm KSPER currents and is critical for normal fertility

C. Lingle, X. Xia, Chengtao Yang, 2015, Proceedings of the National Academy of Sciences.

A Novel Auxiliary Subunit Critical to BK Channel Function in Caenorhabditis elegans

Bojun Chen, Zhao-Wen Wang, Qian Ge, 2010, The Journal of Neuroscience.

Species-speciﬁ c Differences among KCNMB3 BK (cid:2) 3 Auxiliary Subunits: Some (cid:2) 3 N-terminal Variants May Be Primate-speciﬁ c Subunits

C. Lingle, X. Xia, Xu-hui Zeng, 2008 .

Inactivation of BK channels by the NH 2 terminus of the beta 2 auxiliary subunit : An essential role of a terminal peptide segment of three hydrophobic residues

C. Lingle, X. Xia, J. Ding, 2013 .

Cysteine scanning and modification reveal major differences between BK channels and Kv channels in the inner pore region

C. Lingle, X. Xia, Yu Zhou, 2011, Proceedings of the National Academy of Sciences.

Divalent Cation Sensitivity of BK Channel Activation Supports the Existence of Three Distinct Binding Sites

C. Lingle, X. Xia, Xu-hui Zeng, 2005, The Journal of general physiology.

Simultaneous knockout of Slo3 and CatSper1 abolishes all alkalization- and voltage-activated current in mouse spermatozoa

D. Clapham, C. Lingle, X. Xia, 2013, The Journal of general physiology.

Digital Interactions between beta subunits of the KCNMB family and Interactions between beta subunits of the KCNMB family and Slo3: Beta4 selectively modulates Slo3 expression and function Slo3: Beta4 selectively modulates Slo3 expression and function

C. Lingle, X. Xia, Chengtao Yang, 2022 .

Interactions between beta subunits of the KCNMB family and Slo 3 : Beta 4 selectively modulates Slo 3 expression and function

C. Lingle, X. Xia, Chengtao Yang, 2013 .

Simultaneous Knockout of Slo3 and Catsper1 Abolishes All Alkalization-and Voltage-activated Current in Mouse Spermatozoa Recommended Citation

C. Lingle, X. Xia, B. Navarro, 2022 .

Alkalization Gradually Arises, in Part, from Relocation of Sperm from the Acidic Environment

C. Lingle, X. Xia, B. Navarro, 2022 .