Guangyu Wang

发表

The Neuronal Kv4 Channel Complex

M. Covarrubias, Aditya Bhattacharji, J. A. Santiago-Castillo, 2008, Neurochemical Research.

Heat-Dependent Hairpin Melting Drives TRPV1 Opening

Guangyu Wang, 2022, bioRxiv.

Heat-Dependent Hairpin Melting Drives TRPV1 Opening

Guangyu Wang, 2022, bioRxiv.

Heat-dependent Loop Melting Drives TRPV1 Opening

Guangyu Wang, 2022, bioRxiv.

A Novel Potent Anticancer Compound Optimized from a Natural Oridonin Scaffold Induces Apoptosis and Cell Cycle Arrest through the Mitochondrial Pathway.

Zhe-Sheng Chen, Dong-Hua Yang, Shanshan Luo, 2017, Journal of medicinal chemistry.

Redox-dependent Structural Origins of the Temperature Threshold and Sensitivity in the TRPV3 Bio-thermometer

Guangyu Wang, 2022 .

Design, synthesis, and biological evaluation of truncated deguelin derivatives as Hsp90 inhibitors.

Guangyu Wang, Shengtao Xu, Hequan Yao, 2019, European journal of medicinal chemistry.

Design, synthesis, and biological evaluation of NAD(P)H: Quinone oxidoreductase (NQO1)-targeted oridonin prodrugs possessing indolequinone moiety for hypoxia-selective activation.

Guangyu Wang, Shengtao Xu, Hequan Yao, 2017, European journal of medicinal chemistry.

Mechanistic insight into the heme-independent interplay between iron and carbon monoxide in CFTR and Slo1 BKCa channels.

Guangyu Wang, 2017, Metallomics : integrated biometal science.

Voltage-dependent Gating Rearrangements in the Intracellular T1–T1 Interface of a K+ Channel

M. Covarrubias, Guangyu Wang, 2006, The Journal of general physiology.

Functionally Active T1-T1 Interfaces Revealed by the Accessibility of Intracellular Thiolate Groups in Kv4 Channels

M. Covarrubias, Guangyu Wang, P. Pfaffinger, 2005, The Journal of general physiology.

Functionally Active T 1T 1 Interfaces Revealed by the Accessibility of Intracellular Thiolate Groups in Kv 4 Channels

M. Covarrubias, Guangyu Wang, P. Pfaffinger, 2005 .

Zn2+-dependent Redox Switch in the Intracellular T1-T1 Interface of a Kv Channel*

M. Covarrubias, Guangyu Wang, P. Pfaffinger, 2007, Journal of Biological Chemistry.

Lipid-dependent sequential allosteric activation of heat-sensing TRPV1 channels by anchor-stereoselective “hot” vanilloid compounds and analogs

Guangyu Wang, 2021, Biochemistry and biophysics reports.

Design Maps of TRPM8 as a Thermometer for Cold Detection

Guangyu Wang, 2022, bioRxiv.

Ligand-stereoselective allosteric activation of cold-sensing TRPM8 channels by an H-bonded homochiral menthol dimer with head-to-head or head-to-tail.

Guangyu Wang, 2021, Chirality.

Interplay between inhibitory ferric and stimulatory curcumin regulates phosphorylation-dependent human cystic fibrosis transmembrane conductance regulator and ΔF508 activity.

Guangyu Wang, 2015, Biochemistry.

Molecular Basis for Fe(III)-Independent Curcumin Potentiation of Cystic Fibrosis Transmembrane Conductance Regulator Activity.

Guangyu Wang, 2015, Biochemistry.

External Zn2+ binding to cysteine‐substituted cystic fibrosis transmembrane conductance regulator constructs regulates channel gating and curcumin potentiation

Guangyu Wang, Y. Norimatsu, Rheeann Linsley, 2016, The FEBS journal.

Removal of the Fe(iii) site promotes activation of the human cystic fibrosis transmembrane conductance regulator by high-affinity Zn(ii) binding.

Guangyu Wang, 2018, Metallomics : integrated biometal science.

The Inhibition Mechanism of Non-phosphorylated Ser768 in the Regulatory Domain of Cystic Fibrosis Transmembrane Conductance Regulator*

Guangyu Wang, 2010, The Journal of Biological Chemistry.

State-dependent Regulation of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Gating by a High Affinity Fe3+ Bridge between the Regulatory Domain and Cytoplasmic Loop 3*

Guangyu Wang, 2010, The Journal of Biological Chemistry.

Heat-Dependent Hairpin Melting Drives TRPV1 Opening

Guangyu Wang, 2022, SSRN Electronic Journal.

Regulation of Activation and Processing of the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) by a Complex Electrostatic Interaction between the Regulatory Domain and Cytoplasmic Loop 3*

D. Duan, Guangyu Wang, 2012, The Journal of Biological Chemistry.

Double the keys, double the control: coupled phosphorylation sites provide novel molecular targets for precise control of ion channel function. Focus on "Differential regulation of a CLC anion channel by SPAK kinase ortholog-mediated multisite phosphorylation".

D. Duan, Guangyu Wang, 2012, American journal of physiology. Cell physiology.