A. Dulhunty

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Novel regulators of RyR Ca2+ release channels: insight into molecular changes in genetically-linked myopathies

A. Dulhunty, N. Beard, P. Pouliquin, 2006, Journal of Muscle Research & Cell Motility.

Effects of an alpha-helical ryanodine receptor C-terminal tail peptide on ryanodine receptor activity: modulation by Homer.

P. Harvey, M. Casarotto, A. Dulhunty, 2006, The international journal of biochemistry & cell biology.

The membrane capacity of mammalian skeletal muscle fibres

A. Dulhunty, G. Carter, C. Hinrichsen, 1984, Journal of Muscle Research & Cell Motility.

An X-linked channelopathy with cardiomegaly due to a CLIC2 mutation enhancing ryanodine receptor channel activity.

Emil Alexov, Kyoko Takano, Shawn Witham, 2012, Human molecular genetics.

Low resistance junctions in crayfish. Structural changes with functional uncoupling

A. Dulhunty, C. Peracchia, A F Dulhunty, 1976, The Journal of cell biology.

Multiple Actions of the Anthracycline Daunorubicin on Cardiac Ryanodine Receptors

Amy D. Hanna, A. Dulhunty, N. Beard, 2011, Molecular Pharmacology.

Structural and biophysical analyses of the skeletal dihydropyridine receptor β subunit β1a reveal critical roles of domain interactions for stability

N. Norris, A. Oakley, M. Casarotto, 2017, The Journal of Biological Chemistry.

The voltage-gated calcium-channel β subunit: more than just an accessory

M. Casarotto, A. Dulhunty, Yamuna Karunasekara, 2009, European Biophysics Journal.

Interactions between dihydropyridine receptors and ryanodine receptors in striated muscle.

C. Haarmann, D. Green, M. Casarotto, 2002, Progress in biophysics and molecular biology.

Nitric Oxide Activates or Inhibits Skeletal Muscle Ryanodine Receptors Depending on Its Concentration, Membrane Potential and Ligand Binding

A. Dulhunty, J. Hart, 2000, The Journal of Membrane Biology.

Rods in the terminal cisternae of skeletal muscle

A. Dulhunty, 1987, Muscle & nerve.

Indentations in the terminal cisternae of denervated rat EDL and soleus muscle fibers.

P. Gage, A. Dulhunty, A. Valois, 1984, Journal of ultrastructure research.

Differential effects of glycerol treatment on membrane capacity and excitation—contraction coupling in toad sartorius fibres. With an Appendix

P. H. Barry, P. Gage, A. Dulhunty, 1973, The Journal of physiology.

Role of some unconserved residues in the "C" region of the skeletal DHPR II-III loop.

P. Harvey, A. Dulhunty, S. Curtis, 2005, Frontiers in bioscience : a journal and virtual library.

Peptide mimetic compounds can activate or inhibit cardiac and skeletal ryanodine receptors.

G. Lamb, M. Casarotto, C. Easton, 2020, Life sciences.

Triadin Binding to the C-Terminal Luminal Loop of the Ryanodine Receptor is Important for Skeletal Muscle Excitation–Contraction Coupling

I. Marty, A. Dulhunty, N. Beard, 2007, The Journal of general physiology.

Potassium contractures and asymmetric charge movement in extensor digitorum longus and soleus muscles from thyrotoxic rats

G. Lamb, P. Gage, A. Dulhunty, 1987, Journal of Muscle Research & Cell Motility.

Exploiting Peptidomimetics to Synthesize Compounds That Activate Ryanodine Receptor Calcium Release Channels

M. Casarotto, C. Easton, A. Dulhunty, 2018, ChemMedChem.

Molecular interactions of STAC proteins with skeletal muscle dihydropyridine receptor and excitation‐contraction coupling

A. Oakley, M. Casarotto, A. Dulhunty, 2022, Protein science : a publication of the Protein Society.

Ubiquitous SPRY domains and their role in the skeletal type ryanodine receptor

M. Casarotto, A. Dulhunty, Han-Shen Tae, 2009, European Biophysics Journal.

The GSTM2 C-Terminal Domain Depresses Contractility and Ca2+ Transients in Neonatal Rat Ventricular Cardiomyocytes

M. Casarotto, A. Dulhunty, Dan Liu, 2016, PloS one.

Junctin and triadin each activate skeletal ryanodine receptors but junctin alone mediates functional interactions with calsequestrin.

A. Dulhunty, N. Beard, E. Gallant, 2009, The international journal of biochemistry & cell biology.

Ryanodine receptors from rabbit skeletal muscle are reversibly activated by rapamycin

P. Junankar, A. Dulhunty, G. Ahern, 1997, Neuroscience Letters.

Regulation of skeletal ryanodine receptors by dihydropyridine receptor II-III loop C-region peptides: relief of Mg2+ inhibition.

C. Haarmann, A. Dulhunty, D. Laver, 2005, The Biochemical journal.

Molecular Changes in the Cardiac RyR2 With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)

A. Dulhunty, 2022, Frontiers in Physiology.

Ion channels in the sarcoplasmic reticulum of striated muscle.

P. Junankar, A. Dulhunty, D. Laver, 1996, Acta physiologica Scandinavica.

A Skeletal Muscle Ryanodine Receptor Interaction Domain in Triadin

A. Dulhunty, N. Beard, E. Wium, 2012, PloS one.

MOLECULAR RECOGNITION OF THE DISORDERED DIHYDROPYRIDINE RECEPTOR II–III LOOP BY A CONSERVED SPRY DOMAIN OF THE TYPE 1 RYANODINE RECEPTOR

N. Norris, M. Casarotto, A. Dulhunty, 2009, Clinical and experimental pharmacology & physiology.

Skeletal Muscle Ryanodine Receptor Channels Are Activated by the Fungal Metabolite, Gliotoxin

D. Green, P. Waring, A. Dulhunty, 2000, The Journal of Membrane Biology.

Effects of extracellular calcium concentration and dihydropyridines on contraction in mammalian skeletal muscle.

P. Gage, A. Dulhunty, P W Gage, 1988, The Journal of physiology.

Regulation and dysregulation of cardiac ryanodine receptor (RyR2) open probability during diastole in health and disease

Amy D. Hanna, A. Dulhunty, N. Beard, 2012, The Journal of general physiology.

Indentations in the terminal cisternae of amphibian and mammalian skeletal muscle fibers.

A. Dulhunty, A. Valois, 1983, Journal of ultrastructure research.

AuPS/ASB Meeting - Adelaide 2010 Symposium: Stress, disease and Ca2+ management: the cardiovascular challenge. Chair: Lea

A. Dulhunty, N. Beard, D. Laver, 2010 .

How does flecainide impact RyR2 channel function?

A. Dulhunty, J. Fraser, S. Salvage, 2022, The Journal of general physiology.

The inhibitory glutathione transferase M2-2 binding site is located in divergent region 3 of the cardiac ryanodine receptor.

M. Casarotto, A. Dulhunty, Dan Liu, 2012, Biochemical pharmacology.

The structure of the C-terminal helical bundle in glutathione transferase M2-2 determines its ability to inhibit the cardiac ryanodine receptor.

M. Casarotto, A. Dulhunty, Dan Liu, 2010, Biochemical pharmacology.

Muscle-specific GSTM2-2 on the luminal side of the sarcoplasmic reticulum modifies RyR ion channel activity.

A. Dulhunty, N. Beard, E. Gallant, 2008, The international journal of biochemistry & cell biology.

A Ca2+-Activated Anion Channel in the Sarcoplasmic Reticulum of Skeletal Muscle

A. Dulhunty, D. Laver, 2002 .

β‐Adrenergic potentiation of E–C coupling increases force in rat skeletal muscle

S. Cairns, A. Dulhunty, 1993 .

How many cysteine residues regulate ryanodine receptor channel activity?

C. Haarmann, D. Green, A. Dulhunty, 2000, Antioxidants & redox signaling.

The Cysteine-rich Secretory Protein Domain of Tpx-1 Is Related to Ion Channel Toxins and Regulates Ryanodine Receptor Ca2+ Signaling*

M. O’Bryan, J. Swarbrick, M. Scanlon, 2006, Journal of Biological Chemistry.

Dynamic regulation of ryanodine receptor type 1 (RyR1) channel activity by Homer 1.

P. Worley, Xiaohua Shen, P. Allen, 2008, Cell calcium.

A variably spliced region in the type 1 ryanodine receptor may participate in an inter-domain interaction.

A. Dulhunty, N. Beard, S. Pace, 2007, The Biochemical journal.

Excitation-contraction coupling and contractile properties in denervated rat EDL and soleus muscles

A. Dulhunty, 1985, Journal of Muscle Research & Cell Motility.

The rate of tetanic relaxation is correlated with the density of calcium ATPase in the terminal cisternae of thyrotoxic skeletal muscle

A. Dulhunty, 2004, Pflügers Archiv.

C-terminal residues of skeletal muscle calsequestrin are essential for calcium binding and for skeletal ryanodine receptor inhibition

A. Dulhunty, N. Beard, 2015, Skeletal Muscle.

The ryanodine receptor: a pivotal Ca2+ regulatory protein and potential therapeutic drug target.

M. Casarotto, A. Dulhunty, N. Beard, 2011, Current drug targets.

Noninactivating tension in rat skeletal muscle. Effects of thyroid hormone

M. Chua, A. Dulhunty, 1989, The Journal of general physiology.

Effects of Thyroid Homum.

M. Chua, A. Dulhunty, J. Curtin, 1989 .

Internal citrate ions reduce the membrane potential for contraction threshold in mammalian skeletal muscle fibers.

A. Dulhunty, 1988, Biophysical journal.

Ultrastructure of sarcoballs on the surface of skinned amphibian skeletal muscle fibres

P. Junankar, T. Lewis, A. Dulhunty, 1992, Journal of Muscle Research & Cell Motility.

Porin-type1 proteins in sarcoplasmic reticulum and plasmalemma of striated muscle fibres

P. Junankar, F. Thinnes, A. Dulhunty, 1995, Journal of Muscle Research & Cell Motility.

Three residues in the luminal domain of triadin impact on Trisk 95 activation of skeletal muscle ryanodine receptors

A. Dulhunty, N. Beard, E. Wium, 2016, Pflügers Archiv - European Journal of Physiology.

Activation and Inhibition of Skeletal RyR Channels by a Part of the Skeletal DHPR II-III Loop: Effects of DHPR Ser 687 and FKBP12

M. Casarotto, A. Dulhunty, S. Pace, 1999 .

CONTROL OF MUSCLE RYANODINE RECEPTOR CALCIUM RELEASE CHANNELS BY PROTEINS IN THE SARCOPLASMIC RETICULUM LUMEN

A. Dulhunty, N. Beard, Lan Wei, 2009, Clinical and experimental pharmacology & physiology.

A freeze‐fracture study of normal and dystrophic C57BL mouse muscle

A. Dulhunty, Angelo Valois Aaist, 1982, Muscle & nerve.

Unexpected dependence of RyR1 splice variant expression in human lower limb muscles on fiber-type composition

Paul N. Smith, A. Dulhunty, A. Theodoratos, 2016, Pflügers Archiv - European Journal of Physiology.

The relative contributions of the folds and caveolae to the surface membrane of frog skeletal muscle fibres at different sarcomere lengths.

C. Franzini-armstrong, A. Dulhunty, 1975, The Journal of physiology.

Structural determinants for activation or inhibition of ryanodine receptors by basic residues in the dihydropyridine receptor II-III loop.

D. Green, M. Casarotto, A. Dulhunty, 2001, Biophysical journal.

The elusive role of the SPRY2 domain in RyR1

M. Casarotto, A. Dulhunty, E. Gallant, 2011, Channels.

Effects of cobalt, magnesium, and cadmium on contraction of rat soleus muscle.

P. Gage, A. Dulhunty, 1989, Biophysical journal.

Multiple Actions of Imperatoxin A on Ryanodine Receptors

M. Casarotto, A. Dulhunty, S. Curtis, 2004, Journal of Biological Chemistry.

Characteristics of irreversible ATP activation suggest that native skeletal ryanodine receptors can be phosphorylated via an endogenous CaMKII.

C. Haarmann, A. Dulhunty, S. Pace, 2001, Biophysical journal.

Homer and the ryanodine receptor

A. Dulhunty, P. Pouliquin, 2009, European Biophysics Journal.

Effects of ivermectin and midecamycin on ryanodine receptors and the Ca2+‐ATPase in sarcoplasmic reticulum of rabbit and rat skeletal muscle

P. Junankar, A. Dulhunty, S. Pace, 1999, The Journal of physiology.

CHAPTER III – Effects of Toxin from the Blue-Ringed Octopus (Hapalochlaena maculosa)

P. Gage, A. Dulhunty, 1973 .

Selective effects of an octopus toxin on action potentials

P. Gage, A. Dulhunty, 1971, The Journal of physiology.

Skeletal muscle excitation-contraction coupling: who are the dancing partners?

M. Casarotto, A. Dulhunty, N. Beard, 2014, The international journal of biochemistry & cell biology.

Structure of the Janus protein human CLIC2.

Paul M G Curmi, Michael W Parker, P. Curmi, 2007, Journal of molecular biology.

The Glutathione Transferase Structural Family Includes a Nuclear Chloride Channel and a Ryanodine Receptor Calcium Release Channel Modulator*

G. Chelvanayagam, P. Gage, A. Dulhunty, 2001, The Journal of Biological Chemistry.

Heterogeneity of T-tubule geometry in vertebrate skeletal muscle fibres

A. Dulhunty, 1984, Journal of Muscle Research & Cell Motility.

Subconductance states in single-channel activity of skeletal muscle ryanodine receptors after removal of FKBP12.

P. Junankar, A. Dulhunty, G. Ahern, 1997, Biophysical journal.

Arg(615)Cys substitution in pig skeletal ryanodine receptors increases activation of single channels by a segment of the skeletal DHPR II-III loop.

A. Dulhunty, S. Pace, S. Curtis, 2001, Biophysical journal.

Actions of sulfhydryl reagents on single ryanodine receptor Ca(2+)-release channels from sheep myocardium.

A. Dulhunty, K. Eager, L. Roden, 1997, The American journal of physiology.

A freeze-fracture study of extensor digitorum longus and soleus muscle fibers from thyrotoxic rats.

A. Dulhunty, 1986, Journal of ultrastructure and molecular structure research.

Caffeine sensitivity of native RyR channels from normal and malignant hyperthermic pigs: effects of a DHPR II-III loop peptide.

A. Dulhunty, S. Curtis, E. Gallant, 2004, American journal of physiology. Cell physiology.

Reduced inhibitory effect of Mg2+ on ryanodine receptor-Ca2+ release channels in malignant hyperthermia.

G. Lamb, P. Junankar, A. Dulhunty, 1997, Biophysical journal.

Excitation‐contraction coupling and charge movement in denervated rat extensor digitorum longus and soleus muscles.

P. Gage, A. Dulhunty, 1985, The Journal of physiology.

Neutralizing the pathological effects of extracellular histones with small polyanions

P. Madge, L. Khachigian, R. Stephens, 2020, Nature Communications.

Effect of chloride withdrawal on the geometry of the T-tubules in amphibian and mammalian muscle

A. Dulhunty, 2005, The Journal of Membrane Biology.

Glycerol treatment in mammalian skeletal muscle

D. F. Davey, D. Fatkin, A. Dulhunty, 1980, The Journal of Membrane Biology.

Slow potassium contractures in mouse limb muscles.

A. Dulhunty, 1981, The Journal of physiology.

K-contractures and membrane potential in mammalian skeletal muscle

A. Dulhunty, 1977, Nature.

Fiber types in red and white segments of rat sternomastoid muscle.

A. Dulhunty, M. Dlutowski, 1979, The American journal of anatomy.

Electrical properties of toad sartorius muscle fibres in summer and winter

P. Gage, A. Dulhunty, 1973, The Journal of physiology.

A refractory period after brief activation of mammalian skeletal muscle fibres

A. Dulhunty, 1979, Neuroscience Letters.

The dependence of membrane potential on extracellular chloride concentration in mammalian skeletal muscle fibres.

A. Dulhunty, 1978, The Journal of physiology.

Delayed contractures induced by external cadmium ions in rat soleus muscle fibres

A. Dulhunty, J. Mould, 2014, Pflügers Archiv.

Distribution of potassium and chloride permeability over the surface and T-tubule membranes of mammalian skeletal muscle

A. Dulhunty, 1979, The Journal of Membrane Biology.

The contractile properties, histochemistry, ultrastructure and electrophysiology of the cricothyroid and posterior cricoarytenoid muscles in the rat

A. Dulhunty, C. Hinrichsen, 1982, Journal of Muscle Research & Cell Motility.

The effects of β‐adrenoceptor activation on contraction in isolated fast‐ and slow‐twitch skeletal muscle fibres of the rat

S. Cairns, A. Dulhunty, 1993, British journal of pharmacology.

Alternative splicing of RyR1 alters the efficacy of skeletal EC coupling.

J. Lueck, P. Harvey, M. Casarotto, 2009, Cell calcium.

Differential effects of diazepam on rat hindlimb muscles.

M. Chua, A. Dulhunty, 1987, Canadian journal of physiology and pharmacology.

Activation of RyR2 by class I kinase inhibitors

N. Macquaide, V. Staudacher, A. Gamble, 2019, British journal of pharmacology.

3D Mapping of the SPRY2 Domain of Ryanodine Receptor 1 by Single-Particle Cryo-EM

Alex Perálvarez-Marín, Marco G. Casarotto, Angela F. Dulhunty, 2011, PloS one.

The random-coil 'C' fragment of the dihydropyridine receptor II-III loop can activate or inhibit native skeletal ryanodine receptors.

C. Haarmann, D. Green, M. Casarotto, 2003, The Biochemical journal.

Altered mRNA splicing of the skeletal muscle ryanodine receptor and sarcoplasmic/endoplasmic reticulum Ca2+-ATPase in myotonic dystrophy type 1.

J. Lueck, S. Sakoda, M. Nakamori, 2005, Human molecular genetics.

Calsequestrin and the calcium release channel of skeletal and cardiac muscle.

A. Dulhunty, N. Beard, D. Laver, 2004, Progress in biophysics and molecular biology.

The Mu class glutathione transferase is abundant in striated muscle and is an isoform-specific regulator of ryanodine receptor calcium channels.

P. Gage, A. Dulhunty, E. Gallant, 2007, Cell calcium.

Potassium contractures and mechanical activation in mammalian skeletal muscles

A. Dulhunty, 1980, The Journal of Membrane Biology.

Depolarization accelerates the decay of K+ contractures in rat skeletal muscle fibers

A. Dulhunty, Jorgen A. Mould, M. Patterson, 1996, Muscle & nerve.

The voltage-activation of contraction in skeletal muscle.

A. Dulhunty, 1992, Progress in biophysics and molecular biology.

Activation and inactivation of excitation‐contraction coupling in rat soleus muscle.

A. Dulhunty, 1991, The Journal of physiology.

Inactivation of excitation-contraction coupling in rat extensor digitorum longus and soleus muscles

M. Chua, A. Dulhunty, Michael Chua, 1988, The Journal of general physiology.

Asymmetrical charge movement in slow‐ and fast‐twitch mammalian muscle fibres in normal and paraplegic rats.

P. Gage, A. Dulhunty, 1983, The Journal of physiology.

Effects of membrane potential on mechanical activation in skeletal muscle

A. Dulhunty, 1982, The Journal of general physiology.

C-terminal residues of skeletal muscle calsequestrin are essential for calcium binding and for skeletal ryanodine receptor inhibition

A. Dulhunty, N. Beard, 2015, Skeletal Muscle.

Single channel activity of the ryanodine receptor calcium release channel is modulated by FK‐506

P. Junankar, A. Dulhunty, G. Ahern, 1994, FEBS letters.

Immunogold labeling of calcium ATPase in sarcoplasmic reticulum of skeletal muscle: use of 1-nm, 5-nm, and 10-nm gold.

P. Junankar, A. Dulhunty, C. Stanhope, 1993, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.

The effect of diazepam on potassium contractures, contraction threshold, and resting tension in rat skeletal muscles.

M. Chua, A. Dulhunty, 1988, Canadian Journal of Physiology and Pharmacology.

Actions of perchlorate ions on rat soleus muscle fibres.

A. Dulhunty, G. Ahern, P. Zhu, 1992, The Journal of physiology.

Activation of the Cardiac Ryanodine Receptor by Sulfhydryl Oxidation is Modified by Mg2+ and ATP

A. Dulhunty, K. Eager, 1998, The Journal of Membrane Biology.

β1a490-508, a 19-residue peptide from C-terminal tail of Cav1.1 β1a subunit, potentiates voltage-dependent calcium release in adult skeletal muscle fibers.

A. Dulhunty, R. Olojo, Erick O. Hernández-Ochoa, 2014, Biophysical journal.

Magnesium Inhibition of Ryanodine-Receptor Calcium Channels: Evidence for Two Independent Mechanisms

A. Dulhunty, D. Laver, T. Baynes, 1997, The Journal of Membrane Biology.

Oxidation and reduction of pig skeletal muscle ryanodine receptors.

R. Fink, C. Haarmann, A. Dulhunty, 1999, Biophysical journal.

Distribution of calcium ATPase in the sarcoplasmic reticulum of fast- and slow-twitch muscles determined with monoclonal antibodies

A. Dulhunty, C. J. Medveczky, M. Banyard, 2005, The Journal of Membrane Biology.

ß-Adrenergic Stimulation Increases RyR2 Activity via Intracellular Ca2+ and Mg2+ Regulation

Derek R. Laver, Mohammad S. Imtiaz, Nicole A. Beard, 2013, PloS one.

The β(1a) subunit of the skeletal DHPR binds to skeletal RyR1 and activates the channel via its 35-residue C-terminal tail.

M. Casarotto, A. Dulhunty, N. Beard, 2011, Biophysical journal.

What we don't know about the structure of ryanodine receptor calcium release channels

A. Dulhunty, P. Pouliquin, 2003, Clinical and experimental pharmacology & physiology.

Cardiac Ryanodine Receptor Activity is Altered by Oxidizing Reagents in Either the Luminal or Cytoplasmic Solution

A. Dulhunty, K. Eager, 1999, The Journal of Membrane Biology.

A bivalent remipede toxin promotes calcium release via ryanodine receptor activation

I. Vetter, Jennifer J. Smith, M. Mobli, 2023, Nature Communications.

Subcellular distribution of ryanodine receptor-like and calcium ATPase-like immunoreactivity in brainstem and cerebellar neurones of rat and guinea pig

P. Sah, P. Junankar, A. Dulhunty, 1994, Neuroscience Letters.

Ion channel gating in cardiac ryanodine receptors from the arrhythmic RyR2-P2328S mouse

A. Dulhunty, N. Beard, E. Gallant, 2019, Journal of Cell Science.

Inositol Polyphosphates Modify the Kinetics of a Small Chloride Channel in Skeletal Muscle Sarcoplasmic Reticulum

P. Foster, A. Dulhunty, J. Kourie, 1997, The Journal of Membrane Biology.

Extra-junctional ryanodine receptors in the terminal cisternae of mammalian skeletal muscle fibres

P. Junankar, A. Dulhunty, C. Stanhope, 1992, Proceedings of the Royal Society of London. Series B: Biological Sciences.

Cytoplasmic Ca2+ inhibits the ryanodine receptor from cardiac muscle

P. Junankar, A. Dulhunty, D. Laver, 1995, The Journal of Membrane Biology.

Phosphate ion channels in sarcoplasmic reticulum of rabbit skeletal muscle

A. Dulhunty, D. Laver, G. Lenz, 2001, The Journal of physiology.

Regulation of the cardiac muscle ryanodine receptor by glutathione transferases

Marco G. Casarotto, Angela F. Dulhunty, M. Casarotto, 2011, Drug metabolism reviews.

Flecainide Paradoxically Activates Cardiac Ryanodine Receptor Channels under Low Activity Conditions: A Potential Pro-Arrhythmic Action

A. Dulhunty, E. Gallant, J. Fraser, 2021, Cells.

Junctin – the quiet achiever

A. Dulhunty, N. Beard, Lan Wei, 2009, The Journal of physiology.

The conformation of calsequestrin determines its ability to regulate skeletal ryanodine receptors.

M. Varsányi, A. Dulhunty, N. Beard, 2006, Biophysical journal.

Calsequestrin is an inhibitor of skeletal muscle ryanodine receptor calcium release channels.

A. Dulhunty, N. Beard, D. Laver, 2002, Biophysical journal.

The Anthracycline Metabolite Doxorubicinol Abolishes RyR2 Sensitivity to Physiological Changes in Luminal Ca2+ through an Interaction with Calsequestrin

Amy D. Hanna, A. Dulhunty, N. Beard, 2017, Molecular Pharmacology.

Proteins within the intracellular calcium store determine cardiac RyR channel activity and cardiac output

Amy D. Hanna, A. Dulhunty, N. Beard, 2012, Clinical and experimental pharmacology & physiology.

Unique isoform-specific properties of calsequestrin in the heart and skeletal muscle.

Amy D. Hanna, A. Dulhunty, N. Beard, 2009, Cell calcium.

Phosphorylation of skeletal muscle calsequestrin enhances its Ca2+ binding capacity and promotes its association with junctin.

M. Varsányi, A. Dulhunty, N. Beard, 2008, Cell calcium.

Regulation of ryanodine receptors by calsequestrin: effect of high luminal Ca2+ and phosphorylation.

M. Varsányi, M. Casarotto, A. Dulhunty, 2005, Biophysical journal.

A new cytoplasmic interaction between junctin and ryanodine receptor Ca2+ release channels

A. Dulhunty, N. Beard, S. Pace, 2015, Journal of Cell Science.

Multiple targets for flecainide action: implications for cardiac arrhythmogenesis

A. J. Thompson, A. Dulhunty, K. Jeevaratnam, 2018, British journal of pharmacology.

In vitro modulation of the cardiac ryanodine receptor activity by Homer1

A. Dulhunty, P. Pouliquin, S. Pace, 2009, Pflügers Archiv - European Journal of Physiology.

Agonists and antagonists of the cardiac ryanodine receptor: potential therapeutic agents?

M. Casarotto, A. Dulhunty, N. Beard, 2007, Pharmacology & therapeutics.

Regions of ryanodine receptors that influence activation by the dihydropyridine receptor β1a subunit

M. Casarotto, A. Dulhunty, N. Beard, 2015, Skeletal Muscle.

Functional implications of modifying RyR‐activating peptides for membrane permeability

G. Lamb, P. Harvey, I. Toth, 2005, British journal of pharmacology.

Peptide fragments of the dihydropyridine receptor can modulate cardiac ryanodine receptor channel activity and sarcoplasmic reticulum Ca2+ release.

M. Casarotto, A. Dulhunty, S. Curtis, 2004, The Biochemical journal.

Do independent processes control the activation and inactivation of potassium contracture tension in rat skeletal muscle?

A. Dulhunty, P. Zhu, 1993, The Journal of Membrane Biology.

A dihydropyridine receptor alpha1s loop region critical for skeletal muscle contraction is intrinsically unstructured and binds to a SPRY domain of the type 1 ryanodine receptor.

N. Norris, M. Casarotto, A. Dulhunty, 2009, The international journal of biochemistry & cell biology.

Adverse Effects of Doxorubicin and Its Metabolic Product on Cardiac RyR2 and SERCA2A

Amy D. Hanna, A. Dulhunty, N. Beard, 2014, Molecular Pharmacology.

Feedback contributions to excitation–contraction coupling in native functioning striated muscle

A. Dulhunty, K. Jeevaratnam, A. Jackson, 2023, Philosophical Transactions of the Royal Society B.

Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling

M. Casarotto, A. Dulhunty, N. Beard, 2018, F1000Research.

A recently identified member of the glutathione transferase structural family modifies cardiac RyR2 substate activity, coupled gating and activation by Ca2+ and ATP.

P. Gage, A. Dulhunty, P. Pouliquin, 2005, The Biochemical journal.

Letter to the Editor: 1H, 13C and 15N assignments for the II–III loop region of the skeletal dyhydropyridine receptor

P. Harvey, M. Casarotto, A. Dulhunty, 2005, Journal of biomolecular NMR.

Activating the ryanodine receptor with dihydropyridine receptor II-III loop segments: size and charge do matter.

D. Green, M. Casarotto, A. Dulhunty, 2004, Frontiers in bioscience : a journal and virtual library.

A Structural Requirement for Activation of Skeletal Ryanodine Receptors by Peptides of the Dihydropyridine Receptor II-III Loop*

M. Casarotto, F. Gibson, A. Dulhunty, 2000, The Journal of Biological Chemistry.

Activation and inhibition of skeletal RyR channels by a part of the skeletal DHPR II-III loop: effects of DHPR Ser687 and FKBP12.

M. Casarotto, A. Dulhunty, S. Pace, 1999, Biophysical journal.

The passive electrical properties of frog skeletal muscle fibres at different sarcomere lengths.

C. Franzini-armstrong, A. Dulhunty, 1977, The Journal of physiology.

CLIC-2 modulates cardiac ryanodine receptor Ca2+ release channels.

P. Gage, A. Dulhunty, P. Board, 2004, The international journal of biochemistry & cell biology.

Feet, bridges, and pillars in triad junctions of mammalian skeletal muscle: Their possible relationship to calcium buffers in terminal cisternae and T-tubules and to excitation-contraction coupling

A. Dulhunty, 1989, The Journal of Membrane Biology.

Ca2+ signaling in striated muscle: the elusive roles of triadin, junctin, and calsequestrin

A. Dulhunty, N. Beard, Lan Wei, 2009, European Biophysics Journal.

Differential effects of thyroid hormone on T-tubules and terminal cisternae in rat muscles: An electrophysiological and morphometric analysis

G. Lamb, P. Gage, A. Dulhunty, 1986, Journal of Muscle Research & Cell Motility.

Functional and structural characterization of a novel malignant hyperthermia-susceptible variant of DHPR-β1a subunit (CACNB1).

M. Casarotto, A. Dulhunty, D. Bodnár, 2018, American journal of physiology. Cell physiology.

Core skeletal muscle ryanodine receptor calcium release complex

M. Casarotto, A. Dulhunty, N. Beard, 2017, Clinical and experimental pharmacology & physiology.

Physiology and Pharmacology of Ryanodine Receptor Calcium Release Channels.

M. Casarotto, A. Dulhunty, N. Beard, 2017, Advances in pharmacology.

An α‐helical C‐terminal tail segment of the skeletal L‐type Ca2+ channel β1a subunit activates ryanodine receptor type 1 via a hydrophobic surface

L. Weaver, M. Casarotto, A. Dulhunty, 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Slow potential changes in mammalian muscle fibers during prolonged hyperpolarization: Transport number effects and chloride depletion

A. Dulhunty, P. Barry, 2005, The Journal of Membrane Biology.

Characteristics of two types of chloride channel in sarcoplasmic reticulum vesicles from rabbit skeletal muscle.

P W Gage, P. Junankar, P. Gage, 1996, Biophysical journal.

STRUCTURAL AND FUNCTIONAL CHARACTERIZATION OF INTERACTIONS BETWEEN THE DIHYDROPYRIDINE RECEPTOR II–III LOOP AND THE RYANODINE RECEPTOR

P. Harvey, N. Norris, M. Casarotto, 2006, Clinical and experimental pharmacology & physiology.

The three-dimensional structural surface of two beta-sheet scorpion toxins mimics that of an alpha-helical dihydropyridine receptor segment.

G. Lamb, D. Green, M. Casarotto, 2003, The Biochemical journal.

Cyclization of the Intrinsically Disordered α1S Dihydropyridine Receptor II-III Loop Enhances Secondary Structure and in Vitro Function*

M. Casarotto, A. Dulhunty, P. Board, 2011, The Journal of Biological Chemistry.

The recombinant dihydropyridine receptor II-III loop and partly structured 'C' region peptides modify cardiac ryanodine receptor activity.

P. Harvey, M. Casarotto, A. Dulhunty, 2005, The Biochemical journal.

FKBP12 binds to the cardiac ryanodine receptor with negative cooperativity: implications for heart muscle physiology in health and disease

A. Dulhunty, N. Beard, M. G. Casarotto, 2023, Philosophical Transactions of the Royal Society B.

Effects of membrane potential on just detectable movement in rat skeletal muscle: Effects of denervation

A. Dulhunty, M. Patterson, 1994, The Journal of Membrane Biology.

Cadmium withdrawal contractures in rat soleus muscle fibres

A. Dulhunty, Jorgen A. Mould, 2000, Pflügers Archiv.

Association of FK506 binding proteins with RyR channels – effect of CLIC2 binding on sub-conductance opening and FKBP binding

C. Schwartz, M. Casarotto, A. Dulhunty, 2017, Journal of Cell Science.

Ryanodine receptor modification and regulation by intracellular Ca2+ and Mg2+ in healthy and failing human hearts.

C. D. dos Remedios, P. Molenaar, D. V. van Helden, 2017, Journal of molecular and cellular cardiology.

Glutathione transferase M2 variants inhibit ryanodine receptor function in adult mouse cardiomyocytes.

P. Tummala, M. Casarotto, L. Arnolda, 2015, Biochemical pharmacology.

Dissection of the inhibition of cardiac ryanodine receptors by human glutathione transferase GSTM2-2.

M. Casarotto, A. Dulhunty, S. Pace, 2009, Biochemical pharmacology.

A novel cytoplasmic interaction between junctin and ryanodine receptor calcium release channels

A. Dulhunty, N. Beard, S. Pace, 2014 .

Redox potential and the response of cardiac ryanodine receptors to CLIC-2, a member of the glutathione S-transferase structural family.

A. Dulhunty, E. Gallant, P. Board, 2008, Antioxidants & redox signaling.

Upper motor neurone modulation of charge movement and mechanical activation in rat skeletal muscle fibres

P. Gage, A. Dulhunty, 1981, Neuroscience Letters.

Ryanodine receptor Ca2+ release channel post-translational modification: Central player in cardiac and skeletal muscle disease.

A. Dulhunty, N. Beard, A. Denniss, 2018, The international journal of biochemistry & cell biology.

Differences in the regulation of RyR2 from human, sheep, and rat by Ca2+ and Mg2+ in the cytoplasm and in the lumen of the sarcoplasmic reticulum

C. D. dos Remedios, P. Molenaar, D. V. van Helden, 2014, The Journal of general physiology.

Malignant hyperthermia mutation sites in the Leu2442-Pro2477 (DP4) region of RyR1 (ryanodine receptor 1) are clustered in a structurally and functionally definable area.

P. Harvey, M. Casarotto, A. Dulhunty, 2007, The Biochemical journal.

Indentations in the terminal cisternae of slow- and fast-twitch muscle fibers from normal and paraplegic rats.

P. Gage, A. Dulhunty, A. Valois, 1983, Journal of ultrastructure research.

Upper motor neurone modulation of the structure of the terminal cisternae in rat skeletal muscle fibres

P. Gage, A. Dulhunty, A. Valois, 1981, Neuroscience Letters.

Correction: Cardiac ryanodine receptor activation by a high Ca2+ store load is reversed in a reducing cytoplasmic redox environment

Amy D. Hanna, A. Dulhunty, N. Beard, 2016, Journal of Cell Science.

Cardiac ryanodine receptor activation by a high Ca2+ store load is reversed in a reducing cytoplasmic redox environment

Amy D. Hanna, A. Dulhunty, N. Beard, 2014, Journal of Cell Science.

Paralysis of skeletal muscle by butanedione monoxime, a chemical phosphatase

P. Gage, A. Dulhunty, M. W. Fryer, 2004, Pflügers Archiv.

Effects of external cadmium ions on excitation–contraction coupling in rat soleus fibres

A. Dulhunty, Jorgen A. Mould, 1999, Pflügers Archiv.

Calcium ATPase in the sarcoplasmic reticulum of muscle from normal and malignant hyperthermia susceptible pigs

P. Junankar, A. Dulhunty, C. Stanhope, 1991, Neuroscience Letters.

Beta-adrenoceptor activation shows high-frequency fatigue in skeletal muscle fibers of the rat.

S. Cairns, A. Dulhunty, 1994, The American journal of physiology.

Beta-adrenergic potentiation of E-C coupling increases force in rat skeletal muscle.

S. Cairns, A. Dulhunty, 1993, Muscle & nerve.

Regions of ryanodine receptors that influence activation by the dihydropyridine receptor β1a subunit

M. Casarotto, A. Dulhunty, N. Beard, 2015, Skeletal Muscle.

Multiple actions of φ-LITX-Lw1a on ryanodine receptors reveal a functional link between scorpion DDH and ICK toxins

I. Vetter, Jennifer J. Smith, J. Tytgat, 2013, Proceedings of the National Academy of Sciences of the United States of America.

A calcium-activated chloride channel in sarcoplasmic reticulum vesicles from rabbit skeletal muscle.

A. Dulhunty, D. Laver, J. Kourie, 1996, The American journal of physiology.

Multiple targets for flecainide action: implications for cardiac arrhythmogenesis

A. J. Thompson, A. Dulhunty, K. Jeevaratnam, 2018, British journal of pharmacology.

Muscle-specific GSTM2-2 on the luminal side of the sarcoplasmic reticulum modifies RyR ion channel activity.

A. Dulhunty, N. Beard, E. Gallant, 2008, The international journal of biochemistry & cell biology.

Biophysical reviews top five: voltage-dependent charge movement in nerve and muscle

A. Dulhunty, 2023, Biophysical reviews.

Activation and inactivation of excitation‐contraction coupling in rat soleus muscle.

A. Dulhunty, 1991, The Journal of physiology.

ASYMMETRICAL CHARGE MOVEMENT IN NORMAL AND CLYCEROL-TREATED TOAD SARTORIUS FIBRES

P. Gage, A. Dulhunty, P. Barry, 1981 .

Ryanodine receptor phosphorylation in human heart failure

P. Molenaar, A. Dulhunty, N. Beard, 2010 .

Cyclization of the Intrinsically Disordered α1S Dihydropyridine Receptor II-III Loop Enhances Secondary Structure and in Vitro Function*

M. Casarotto, A. Dulhunty, P. Board, 2011, The Journal of Biological Chemistry.