S. Fujii

发表

X-ray crystal structure determination and molecular dynamics simulation of prophospholipase A2 inhibited by amide-type substrate analogues.

K. Tomoo, S. Katsumura, T. Ishida, 1997, Biochimica et biophysica acta.

Novel inhibition mechanism of Bacillus cereus sphingomyelinase by beryllium fluoride.

K. Ikeda, S. Fujii, H. Ikezawa, 2004, Archives of biochemistry and biophysics.

The inhibitory mechanism of bovine pancreatic phospholipase A2 by aldehyde terpenoids

Katsunori Tanaka, S. Katsumura, K. Ikeda, 1999 .

Phospholipase A2 inhibition by manoalide: development of simple analogues and necessary functional groups for inhibition

S. Katsumura, K. Ikeda, S. Fujii, 1992 .

Catalytic and Toxicity Mechanisms of Secretory Phospholipases A2

K. Ikeda, S. Fujii, K. Hayashi, 1998 .

Activation of sphingomyelinase from Bacillus cereus by Zn2+ hitherto accepted as a strong inhibitor.

K. Ikeda, S. Fujii, H. Ikezawa, 2005, Archives of biochemistry and biophysics.

Chromogenic assay for the activity of sphingomyelinase from Bacillus cereus and its application to the enzymatic hydrolysis of lysophospholipids.

K. Ikeda, S. Fujii, H. Ikezawa, 2004, Biological & pharmaceutical bulletin.

Production of nerve growth factor enhanced in cultured mouse astrocytes by glycerophospholipids, sphingolipids, and their related compounds

K. Ikeda, S. Fujii, K. Hayashi, 2007, Molecular and Cellular Biochemistry.

An efficient synthesis of short-chain sphingomyelin analogs and their susceptibility to hydrolysis catalyzed by sphingomyelinase

S. Katsumura, K. Ikeda, S. Fujii, 1997 .

Synthesis of a new phospholipase A2inhibitor of an aldehyde terpenoid and its possible inhibitory mechanism

Katsunori Tanaka, S. Katsumura, K. Ikeda, 1998 .

Synthesis of sphingomyelin sulfur analogue and its behavior toward sphingomyelinase.

S. Katsumura, K. Ikeda, S. Fujii, 2005, Bioorganic & medicinal chemistry letters.

Design and synthesis of new secretory phospholipase A2 inhibitor of a phospholipid analog.

S. Katsumura, K. Ikeda, M. Segawa, 1998, Bioorganic & medicinal chemistry letters.

Synthesis of sphingomyelin carbon analogues as sphingomyelinase inhibitors.

S. Katsumura, K. Ikeda, S. Fujii, 2002, The Journal of organic chemistry.

pH dependence of the reaction rate of p-bromophenacyl bromide and of the binding constants of Ca2+ and an amide-type substrate analog to bovine pancreatic phospholipase A2.

S. Katsumura, K. Ikeda, S. Fujii, 1998, Archives of biochemistry and biophysics.

His151 and His296 are the acid-base catalytic residues of Bacillus cereus sphingomyelinase in sphingomyelin hydrolysis.

K. Ikeda, S. Fujii, M. Imagawa, 2003, Biological & pharmaceutical bulletin.

New phospholipase A2 inhibitor: synthesis and inhibition mechanism of oxazolidinone phospholipid analog.

S. Katsumura, K. Ikeda, S. Fujii, 1995, Bioorganic & medicinal chemistry.

Synthesis of sphingomyelin difluoromethylene analogue

S. Katsumura, K. Ikeda, S. Fujii, 2006 .

Role of Ca2+ in the substrate binding and catalytic functions of snake venom phospholipases A2.

K. Ikeda, K. Hayashi, S. Fujii, 1989, Journal of biochemistry.

Mg2+ binding and catalytic function of sphingomyelinase from Bacillus cereus.

M. Tomita, K. Ikeda, S. Fujii, 1998, Journal of biochemistry.

Binding mode of phospholipase A2 with a new type of phospholipid analog having an oxazolidinone ring.

S. Katsumura, K. Ikeda, K. Hayashi, 1995, Journal of biochemistry.

Roles of asp126 and asp156 in the enzyme function of sphingomyelinase from Bacillus cereus.

S. Katsumura, M. Tomita, K. Ikeda, 1999, Journal of biochemistry.

Synthesis of a New Phospholipase A2 Inhibitor of an Aldehyde Terpenoid and Its Possible Inhibitory Mechanism.

Katsunori Tanaka, S. Katsumura, S. Fujii, 1998 .