N. Gensmantel

发表

Combined quantum mechanical–molecular mechanical study of catalysis by the enzyme phospholipase A2: an investigation of the potential energy surface for amide hydrolysis

I. H. Hillier, B. Waszkowycz, N. Gensmantel, 1991 .

A quantum mechanical/molecular mechanical model of inhibition of the enzyme phospholipase A2

I. H. Hillier, B. Waszkowycz, N. Gensmantel, 1991 .

A combined quantum mechanical/molecular mechanical model of the potential energy surface of ester hydrolysis by the enzyme phospholipase A2

Bohdan Waszkowycz, I. H. Hillier, B. Waszkowycz, 1991 .

A semiempirical molecular orbital and dynamic NMR study of conformational isomerism in angiotensin-converting enzyme inhibitors

G. Morris, I. H. Hillier, N. Gensmantel, 1991 .

Discovery of new non-phospholipid inhibitors of the secretory phospholipases A2.

N. Gensmantel, H. Beaton, S. Connolly, 1994, Journal of medicinal chemistry.

Metal ion catalysis in the aminolysis of penicillin

N. Gensmantel, M. Page, E. Gowling, 1978 .

The chemical reactivity of penicillins and other β-lactam antibiotics

N. Gensmantel, M. Page, P. Proctor, 1982 .

Flavones. 3. Synthesis, biological activities, and conformational analysis of isoflavone derivatives and related compounds.

N. Gensmantel, L. Radov, J. Loch, 1992, Journal of medicinal chemistry.

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase

J. Tainer, E. Getzoff, R. Rosenfeld, 2008, Nature chemical biology.

Metal-ion catalysed hydrolysis of some β-lactam antibiotics

N. Gensmantel, M. Page, P. Proctor, 1980 .

The micelle-catalysed hydrolysis of benzylpenicillin

N. Gensmantel, M. Page, 1982 .

The aminolysis of penicillin derivatives. Rate constants for the formation and breakdown of the tetrahedral addition intermediate

N. Gensmantel, M. Page, 1979 .

Design and synthesis of some substrate analogue inhibitors of phospholipase A2 and investigations by NMR and molecular modeling into the binding interactions in the enzyme-inhibitor complex.

W U Primrose, G. Roberts, G. Roberts, 1992, Journal of medicinal chemistry.

3.9. Toxicokinetics and Metabolism

Vera Rogiers, Sandra Coecke, Amin Rostami-Hodjegan, 2005, Alternatives to laboratory animals : ATLA.

Drug permeation through human skin II: Permeability of ionizable compounds.

Geoffrey Lee, N. Gensmantel, J. Swarbrick, 1984, Journal of pharmaceutical sciences.

A theoretical study of hydrolysis by phospholipase A2: the catalytic role of the active site and substrate specificity

Bohdan Waszkowycz, I. H. Hillier, B. Waszkowycz, 1990 .

The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS).

Glen Andrews, Paul D Leeson, Anders Åberg, 2011, Bioorganic & medicinal chemistry letters.

The effect of increasing the hydrophobicity of penicillin on its micelle-catalysed hydrolysis

N. Gensmantel, M. Page, 1982 .

Toxicokinetics and metabolism.

V. Rogiers, M. Monshouwer, J. J. van de Sandt, 2005, Alternatives to laboratory animals : ATLA.