H. Kempski

发表

Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.

K. Anderson, M. Greaves, M. Greaves, 2009, Blood.

Genetic variegation of clonal architecture and propagating cells in leukaemia

K. Anderson, M. Greaves, T. Enver, 2011, Nature.

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia

M. Stratton, P. Campbell, S. O'meara, 2014, Nature Genetics.

Mutations of JAK2 in acute lymphoblastic leukaemias associated with Down's syndrome

G. Wainreb, A. Green, A. Borkhardt, 2008, The Lancet.

Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia.

K. Anderson, M. Greaves, L. Kearney, 2009, Blood.

In utero origin of t(8;21) AML1-ETO translocations in childhood acute myeloid leukemia.

Ana-Teresa Maia, M. Greaves, Luoping Zhang, 2002, Blood.

Two categories of synovial sarcoma defined by divergent chromosome translocation breakpoints in Xp11.2, with implications for the histologic sub-classification of synovial sarcoma.

P. Cin, C. Fletcher, H. Sonobe, 1995, Cytogenetics and cell genetics.

Pilot study to investigate the possibility of cytogenetic and physiological changes in bio-electrosprayed human lymphocyte cells.

A. Roe, S. Jayasinghe, H. Kempski, 2008, Regenerative medicine.

An investigation of the t(12;21) rearrangement in children with B‐precursor acute lymphoblastic leukaemia using cytogenetic and molecular methods

H. Kempski, J. Chessells, P. Brickell, 1999, British journal of haematology.

Neuroblastoma in monozygotic twins – a case of probable twin-to-twin metastasis

T. Gordon, D. Rampling, H. Kempski, 2002, British Journal of Cancer.

Mutations of JAK 2 in acute lymphoblastic leukaemias associated with Down ’ s syndrome

G. Wainreb, A. Green, A. Borkhardt, 2008 .

Previously unidentified complex cytogenetic changes found in a pediatric case of solid-pseudopapillary neoplasm of the pancreas.

N. Sebire, H. Kempski, J. Anderson, 2006, Cancer genetics and cytogenetics.

leukemia (BCP-ALL) translocations in B-cell precursor acute lymphoblastic IGH recurrent transcription factor family are targeted by CEBP Five members of the

R. Siebert, A. Hagemeijer, M. Calasanz, 2011 .

Isolation and characterisation of a panel of cosmids which allows unequivocal identification of chromosome deletions involving the RB1 gene using fluorescence in situ hybridisation.

J. Cowell, H. Kempski, R. Jaju, 1994, Journal of medical genetics.

Paediatric myelodysplastic syndromes and juvenile myelomonocytic leukaemia in the UK: a population‐based study of incidence and survival

C. Stiller, H. Kempski, I. Hann, 2003, British journal of haematology.

Specific JAK 2 mutation ( JAK 2 R 683 ) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia

K. Anderson, M. Greaves, L. Kearney, 2009 .

NOTCH1 mutation can be an early, prenatal genetic event in T-ALL.

M. Eguchi, M. Greaves, H. Kempski, 2008, Blood.

NOTCH 1 mutation can be an early , prenatal genetic event in TALL

M. Eguchi, M. Greaves, H. Kempski, 2007 .

Prenatal chromosomal diversification of leukemia in monozygotic twins

M. Greaves, L. Kearney, H. Kempski, 2003, Genes, chromosomes & cancer.

A case of acute monocytic leukemia with t(11;17) involving a rearrangement of MLL-1 and a region proximal to the RARA gene.

L. Kearney, E. Solomon, F. Cotter, 1994, Cancer genetics and cytogenetics.

Five members of the CEBP transcription factor family are targeted by recurrent IGH translocations in B-cell precursor acute lymphoblastic leukemia (BCP-ALL).

Takashi Akasaka, Aneela Majid, Renata Walewska, 2007, Blood.

PAX5 alterations in genetically unclassified childhood Precursor B‐cell acute lymphoblastic leukaemia

H. Kempski, A. Ford, P. Ancliff, 2015, British journal of haematology.

Loss of heterozygosity and microsatellite instability at the MLL locus are common in childhood acute leukemia, but not in infant acute leukemia.

H. Kempski, I. Golovleva, J. Chessells, 1999, Blood.

Mutations in exon 2 of GATA1 are early events in megakaryocytic malignancies associated with trisomy 21.

A. Teigler‐Schlegel, O. Haas, D. Bercovich, 2003, Blood.

Cryptic deletions and inversions of chromosome 21 in a phenotypically normal infant with transient abnormal myelopoiesis: a molecular cytogenetic study

H. Kempski, J. Chessells, B. Reeves, 1998, British journal of haematology.

The Genomic Landscape of TEL-AML1+ (ETV6-RUNX1) Acute Lymphoblastic Leukaemia

M. Stratton, P. Futreal, P. Campbell, 2011 .

Salvage of patients with acute promyelocytic leukaemia with residual disease following ABMT performed in second CR using all‐trans retinoic acid

R. Jamal, P. Veys, D. Grimwade, 1998, British journal of haematology.

A case of myelodysplasia with eosinophilia having a translocation t(5;12)(q31;q13) restricted to myeloid cells but not involving eosinophils

H. Kempski, B. Reeves, K. Jani, 1994, British journal of haematology.

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group.

E. Domany, A. Borkhardt, D. Bercovich, 2010, Blood.

The Characterization of Chromosomal Abnormalities Using Fluorescence In SituHybridization Procedures.

H. Kempski, 1996, Methods in molecular medicine.

Down syndrome acute lymphoblastic leukemia R 683 ) and multiple gene deletions in JAK 2 mutation ( JAK 2 Specific

K. Anderson, M. Greaves, L. Kearney, 2009 .

Insertional mutagenesis combined with acquired somatic mutations causes leukemogenesis following gene therapy of SCID-X1 patients.

Christine Kinnon, Christof von Kalle, Michael Hubank, 2008, The Journal of clinical investigation.

A G-quadruplex telomere targeting agent produces p16-associated senescence and chromosomal fusions in human prostate cancer cells.

Stephen Neidle, S. Neidle, L. Kèlland, 2004, Molecular cancer therapeutics.

Characterization of the t(17;19) translocation by gene-specific fluorescent in situ hybridization-based cytogenetics and detection of the E2A-HLF fusion transcript and protein in patients' cells.

S. Bailey, M. Neat, H. Kempski, 2006, Haematologica.

Two novel activating mutations in the Wiskott-Aldrich syndrome protein result in congenital neutropenia.

Christine Kinnon, Austen Worth, A. Worth, 2006, Blood.

Localization of the 8;13 translocation breakpoint associated with myeloproliferative disease to a 1.5 mbp region of chromosome 13

J. Goldman, T. Roberts, N. Cross, 1995, Genes, chromosomes & cancer.

mutated JAK2: a report from the International BFM Study Group disease in which aberrant expression of CRLF2 is associated with Down syndrome acute lymphoblastic leukemia, a highly heterogeneous

E. Domany, A. Borkhardt, D. Bercovich, 2013 .

Long‐term follow‐up of relapsed childhood acute lymphoblastic leukaemia

P. Veys, H. Kempski, I. Hann, 2003, British journal of haematology.

Clinical features, cytogenetics and outcome in acute lymphoblastic and myeloid leukaemia of infancy: report from the MRC Childhood Leukaemia working party

H. Kempski, K. Wheatley, G. Harrison, 2002, Leukemia.

Overexpression of the Ikaros 6 isoform is restricted to t(4;11) acute lymphoblastic leukaemia in children and infants and has a role in B‐cell survival

H. Kempski, A. Ruiz, H. Brady, 2004, British journal of haematology.

The MLL recombinome of acute leukemias

M. D. Boer, R. Pieters, R. Pieters, 2006, Leukemia.

Heterogeneity of the 7q36 breakpoints in the t(7;12) involving ETV6 in infant leukemia

S. Scherer, L. Kearney, J. Harbott, 2003, Genes, chromosomes & cancer.

Distinctive genotypes in infants with T‐cell acute lymphoblastic leukaemia

J. Soulier, E. Clappier, M. Greaves, 2015, British journal of haematology.

Array comparative genome hybridization analysis of acute lymphoblastic leukaemia and acute megakaryoblastic leukaemia in patients with Down syndrome

L. Kearney, S. Izraeli, J. Cowell, 2008, British journal of haematology.

Prospective gene expression analysis accurately subtypes acute leukaemia in children and establishes a commonality between hyperdiploidy and t(12;21) in acute lymphoblastic leukaemia

Zhiyuan Luo, Vaskar Saha, Tony Bellotti, 2005, British journal of haematology.

Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

Christine Kinnon, David G. Spiller, Adrian J. Thrasher, 2007, The Journal of experimental medicine.

Cohort analysis of FISH testing of CD138+ cells in relapsed multiple myeloma: implications for prognosis and choice of therapy

H. Kempski, K. Yong, Laura A Percy, 2015, British journal of haematology.

Spontaneous remission of congenital leukemia: a case for conservative treatment.

R. Grundy, H. Kempski, M. Malone, 2000, Journal of pediatric hematology/oncology.

Cohort Analysis of FISH Testing of CD138+Cells in Relapsed Multiple Myeloma: Implications for Prognosis and Choice of Therapy

H. Kempski, K. Yong, S. Chatters, 2014 .

Comparative expressed sequence hybridization studies of high‐hyperdiploid childhood acute lymphoblastic leukemia

Anthony V Moorman, Fiona M Ross, M. Greaves, 2004, Genes, chromosomes & cancer.

A case of acute megakaryoblastic leukaemia with t(X;6)(p11.21;q23) having an X chromosome breakpoint within a 450-Kb region which is also disrupted in two classes of solid tumours.

H. Kempski, P. Renwick, J. Knight, 1995, Leukemia.

Kostmann's disease, recombinant HuG‐CSF, monosomy 7 and MDS/AML

O. Smith, H. Kempski, B. Reeves, 1995, British journal of haematology.

DOWN'S Syndrome Acute Lymphoblastic LEUKEMIA: A HIGHLY Heterogeneous DISEASE DRIVEN by an Aberrant CRLF2/JAK2 Cooperation – A REPORT FROM the Ibfm-STUDY GROUP.

E. Domany, D. Bercovich, G. Kronnie, 2009 .

t(7;12)(q36;p13), a new recurrent translocation involving ETV6 in infant leukemia

S. Scherer, L. Kearney, A. Teigler‐Schlegel, 2000, Genes, chromosomes & cancer.

Specific JAK2 mutation (JAK2R683) and multiple gene deletions in Down syndrome acute lymphoblastic leukemia.

M. Greaves, L. Kearney, S. Horsley, 2009, Blood.

Down syndrome acute lymphoblastic leukemia, a highly heterogeneous disease in which aberrant expression of CRLF2 is associated with mutated JAK2: a report from the International BFM Study Group.

E. Domany, R. Arceci, A. Borkhardt, 2010, Blood.

Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.

M. Greaves, L. Kearney, C. Eckert, 2009, Blood.

Unregulated actin polymerization by WASp causes defects of mitosis and cytokinesis in X-linked neutropenia

D. Spiller, M. White, A. Thrasher, 2007, The Journal of experimental medicine.

PAX5 alterations in genetically unclassified childhood Precursor B‐cell acute lymphoblastic leukaemia

H. Kempski, A. Ford, P. Ancliff, 2015, British journal of haematology.