D. Keeling

发表

Early factor VIII exposure and subsequent inhibitor development in children with severe haemophilia A

D. Stirling, R. Liesner, Angela E. Thomas, 2007, Haemophilia : the official journal of the World Federation of Hemophilia.

Guidelines on oral anticoagulation with warfarin – fourth edition

D. Perry, T. Baglin, M. Makris, 2011, British journal of haematology.

The use of artificial neural network analysis can improve the risk‐stratification of patients presenting with suspected deep vein thrombosis

D. Keeling, H. Katz, J. Willan, 2019, British journal of haematology.

Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes

William J. Astle, Dorothy A. Thompson, Sri V. V. Deevi, 2018, American journal of human genetics.

Duration of anticoagulation: decision making based on absolute risk.

D. Keeling, 2006, Blood reviews.

Platelet Assays and Platelet Dysfunction

Paul J. Harrison, D. Keeling, 2012 .

CHAPTER 23 – Clinical Tests of Platelet Function

Paul J. Harrison, D. Keeling, 2007 .

Prevention of central venous catheter associated thrombosis using minidose warfarin in patients with haematological malignancies

R. Marcus, T. Baglin, P. Mahendra, 1998, British journal of haematology.

Effects on routine coagulation screens and assessment of anticoagulant intensity in patients taking oral dabigatran or rivaroxaban: Guidance from the British Committee for Standards in Haematology

T. Baglin, S. Kitchen, D. Keeling, 2012, British journal of haematology.

Venous thromboembolism: risk of recurrence and long-term anticoagulation.

D. Keeling, M. Desborough, Leila Khalil, 2015, British journal of hospital medicine.

Platelet Membrane Receptors and Signalling Pathways: New Therapeutic Targets

M. Hollenberg, S. Watson, D. Keeling, 1999 .

The diagnosis of deep vein thrombosis in symptomatic outpatients and the potential for clinical assessment and D‐dimer assays to reduce the need for diagnostic imaging

H. Watson, D. Keeling, A. Moody, 2004, British journal of haematology.

A practical guideline for the haematological management of major haemorrhage

S. Stanworth, D. Keeling, B. Hunt, 2015, British journal of haematology.

Diagnostic importance of the two‐stage factor VIII:C assay demonstrated by a case of mild haemophilia associated with His1954 → Leu substitution in the factor VIII A3 domain

D. Keeling, J. Lloyd, N. Waseem, 1999, British journal of haematology.

35 – Drugs affecting blood coagulation, fibrinolysis, and hemostasis

D. Keeling, 2007 .

The diagnosis of von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors’ Organization

M. Laffan, K. Pasi, P. Collins, 2004, Haemophilia : the official journal of the World Federation of Hemophilia.

Controversies in venous thromboembolism--2015.

F. Klok, D. Keeling, G. Le Gal, 2016, Blood reviews.

Management of Venous Thromboembolism

T. Baglin, D. Keeling, 2015 .

Management of venous thromboembolism – controversies and the future

D. Keeling, R. Alikhan, 2013, British journal of haematology.

Guideline on aspects of cancer‐related venous thrombosis

R. Tait, M. Makris, M. Laffan, 2015, British journal of haematology.

Peri‐operative management of anticoagulation and antiplatelet therapy

R. Tait, H. Watson, D. Keeling, 2016, British journal of haematology.

Idarucizumab for dabigatran overdose in a child

D. Keeling, A. Khan, S. Shapiro, 2018, British journal of haematology.

Hormone replacement therapy, thrombosis and thrombophilia

D. Keeling, 2005, The journal of the British Menopause Society.

Is there a benefit in computed tomography screening for cancer in patients with unprovoked proximal deep venous thrombosis? A cohort study in the Oxford University Hospitals NHS Trust

J. Palmer, D. Keeling, C. Hildyard, 2016, British journal of haematology.

Managing antiplatelet and anticoagulant drugs in patients undergoing elective ophthalmic surgery

B. Prendergast, R. Mukherjee, N. Ruparelia, 2014, British Journal of Ophthalmology.

Platelet hyperactivity and risk of recurrent thrombosis

Paul J. Harrison, D. Keeling, 2006, Journal of thrombosis and haemostasis : JTH.

The aspirin story – from willow to wonder drug

D. Keeling, M. Desborough, 2017, British journal of haematology.

D-dimer test for excluding the diagnosis of pulmonary embolism.

F. Chappell, D. Keeling, F. Crawford, 2016, The Cochrane database of systematic reviews.

Whole genome sequencing of a sporadic primary immunodeficiency cohort

William J. Astle, Sri V. V. Deevi, Kenneth G. C. Smith, 2018, Nature.

Guidelines on the diagnosis and management of heparin‐induced thrombocytopenia: second edition

H. Watson, D. Keeling, S. Davidson, 2012, British journal of haematology.

The management of heparin‐induced thrombocytopenia

H. Watson, D. Keeling, S. Davidson, 2006, British journal of haematology.

Next ‐ generation sequencing for the diagnosis of MYH9 ‐ RD

Sri V. V. Deevi, K. Stirrups, W. Ouwehand, 2019 .

Predicting the future: it’s not a SNP

D. Keeling, 2008, Journal of thrombosis and haemostasis : JTH.

Reversal of asymptomatic over‐anticoagulation by orally administered vitamin K

D. Keeling, K. Paddon, P. Baker, 2006, British journal of haematology.

ALA‐10 MUTATIONS IN THE FACTOR IX PROPEPTIDE AND HAEMORRHAGE IN A PATIENT TREATED WITH WARFARIN

P. Giangrande, D. Keeling, K. Clarke, 2000, British journal of haematology.

Metronidazole causes an unexpected rise in INR in anticoagulated patients even after warfarin has been stopped

D. Keeling, A. Tonna, I. Tonna, 2007 .

Hormone Replacement Therapy and Venous Thromboembolism

D. Keeling, 1999 .

Management of von Willebrand disease: a guideline from the UK Haemophilia Centre Doctors' Organization

G. Dolan, M. Laffan, K. Pasi, 2004, Haemophilia : the official journal of the World Federation of Hemophilia.

Myocardial infarction following recombinant activated factor VII in a patient with type 2A von Willebrand disease.

D. Keeling, I. Basso, 2004, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

The story of the discovery of heparin and warfarin

D. Keeling, D. Wardrop, 2008, British journal of haematology.

The management of heparin‐induced thrombocytopenia

H. Watson, D. Keeling, Henry G. Watson, 2006, British journal of haematology.

Patient self‐testing and self‐management of oral anticoagulation with vitamin K antagonists: guidance from the British Committee for Standards in Haematology

D. Fitzmaurice, C. Heneghan, D. Keeling, 2014, British journal of haematology.

Variant CJD infection in the spleen of a neurologically asymptomatic UK adult patient with haemophilia

S. Love, S. Cousens, J. Ironside, 2010, Haemophilia : the official journal of the World Federation of Hemophilia.

Acquired hemophilia A in the United Kingdom: a 2-year national surveillance study by the United Kingdom Haemophilia Centre Doctors' Organisation.

T. Baglin, M. Makris, R. Liesner, 2007, Blood.

Variation in inhibitor reactivity in acquired haemophilia A with different concentrates.

P. Giangrande, D. Keeling, K. Sukhu, 2000, Clinical and laboratory haematology.

Guideline on the selection and use of therapeutic products to treat haemophilia and other hereditary bleeding disorders

M. Makris, D. Keeling, C. Tait, 2008, Haemophilia : the official journal of the World Federation of Hemophilia.

Thrombophilia screening or screaming

D. Keeling, 2010, Journal of thrombosis and haemostasis : JTH.

Diagnosis and management of heritable thrombophilias

D. Keeling, P. Maccallum, L. Bowles, 2014, BMJ : British Medical Journal.

A single dose of Low‐molecular‐weight Heparin (LMWH) invalidates the use of D‐dimer as part of a Deep Vein Thrombosis (DVT) diagnostic algorithm

D. Keeling, P. Baker, 2017, International journal of laboratory hematology.

Stockings to prevent post-thrombotic syndrome-where are we now?

D. Keeling, 2018, The Lancet. Haematology.

The diagnosis and management of factor VIII and IX inhibitors: a guideline from the UK Haemophilia Centre Doctors' Organization (UKHCDO).

T. Baglin, P. Collins, C. Hay, 2000 .

Anti-DNA antibodies in the primary antiphospholipid syndrome (PAPS)

D. Isenberg, G. Hughes, D. Keeling, 1993, British journal of rheumatology.

The use of rituximab in two children with allo‐antibodies towards factor VIII

S. Stanworth, D. Keeling, N. Curry, 2006, British journal of haematology.

Management of muscle haematomas in patients with severe haemophilia in an evidence‐poor world

G. Benson, P. McLaughlin, M. Makris, 2012, Haemophilia : the official journal of the World Federation of Hemophilia.

Comment on Guidelines on oral anticoagulation with warfarin – 4th edition. Response to Gosai & Muthusamy

D. Keeling, 2012 .

Comparison of an immuno‐turbidometric method (STalia®d‐DI) with an established enzyme linked fluorescent assay (VIDAS®) d‐dimer for the exclusion of venous thromboembolism

D. Keeling, K. Sukhu, P. Baker, 2008, International journal of laboratory hematology.

Time for a redefinition of type 2m von willebrand disease

D. Keeling, 2002, British journal of haematology.

Reducing the need for diagnostic imaging in suspected cases of deep vein thrombosis

D. Keeling, J. Willan, 2019, British journal of haematology.

The prevalence of the cysteine1584 variant of von Willebrand factor is increased in type 1 von Willebrand disease: co‐segregation with increased susceptibility to ADAMTS13 proteolysis but not clinical phenotype

K. Khair, P. Collins, D. Keeling, 2005, British journal of haematology.

Cancer Screening in Unprovoked Venous Thromboembolism

D. Keeling, 2017 .

Authors’ response

B. Prendergast, R. Mukherjee, N. Ruparelia, 2014, British Journal of Ophthalmology.

Activated protein C resistance acquired through liver transplantation.

D. Keeling, Beena Pushkaran, D. Adams, 2005, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

ORIGINAL ARTICLE: Comparison of a point of care device against current laboratory methodology using citrated and EDTA samples for the determination of D‐dimers in the exclusion of proximal deep vein thrombosis

J. Atherton, D. Keeling, P. Baker, 2010, International journal of laboratory hematology.

Audit of anticoagulation after embolectomy for acute ischaemia.

L. Hands, D. Keeling, R. Wathes, 2009, Annals of the Royal College of Surgeons of England.

Coagulation inhibition in venous thrombosis.

D. Keeling, H. Heijboer, D. Brandjes, 1991, The New England journal of medicine.

Procedures for the outpatient management of patients with deep venous thrombosis.

D. Keeling, M. Winter, H. Cohen, 2005, Clinical and laboratory haematology.

Management of bleeding in patients taking FXa and FIIa inhibitors

F. Cotter, D. Keeling, 2013, British journal of haematology.

A case of fatal pulmonary embolism raising questions about the dosing regimen for dalteparin in the very obese

D. Keeling, R. Levison, Andrew Walden, 2008, British journal of haematology.

Have You Been HIT?

D. Keeling, A. Handa, M. Weisters, 2011, Angiology.

The use of age-dependent D-dimer cut-off values to exclude deep vein thrombosis. Reply to “Using an age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excluded”. Haematologica 2012;97(10):1507-13

D. Keeling, K. Cairns, A. Hamblin, 2012, Haematologica.

Recommendations from the British Committee for Standards in Haematology and National Patient Safety Agency

D. Perry, T. Baglin, H. Watson, 2007, British journal of haematology.

Cryoprecipitate prepared from plasma virally inactivated by the solvent detergent method

L. Williamson, D. Keeling, D. Keeling, 1997, British journal of haematology.

Relation between acute hypoxia and activation of coagulation in human beings

P. Robbins, D. Keeling, P. Harrison, 2003, The Lancet.

A simple inhibitor screen is more sensitive than a Bethesda assay in monitoring for the development of inhibitors in haemophilia A and B

D. Keeling, K. Sukhu, J. Beavis, 2005, British journal of haematology.

An investigation of the von Willebrand factor genotype in UK patients diagnosed to have type 1 von Willebrand disease

P. Collins, C. Hay, D. Keeling, 2006, Thrombosis and Haemostasis.

D-dimer for the exclusion of venous thromboembolism: comparison of a new automated latex particle immunoassay (MDA D-dimer) with an established enzyme-linked fluorescent assay (VIDAS D-dimer).

D. Keeling, P. Baker, M. Wright, 1999, Clinical and laboratory haematology.

Fatal thromboembolism in acute promyelocytic leukaemia treated with a combination of all-trans retinoic acid and aprotonin.

T. Baglin, P. Mahendra, D. Keeling, 2010, Clinical and laboratory haematology.

Changing patterns of bleeding in patients with severe haemophilia A

G. Dolan, D. Stephensen, G. Dolan, 2009, Haemophilia : the official journal of the World Federation of Hemophilia.

The use of enhanced half‐life coagulation factor concentrates in routine clinical practice: guidance from UKHCDO

K. Pasi, P. Collins, S. Rangarajan, 2016, Haemophilia : the official journal of the World Federation of Hemophilia.

R. Liesner, R. Liesner, T. Yee, 2011, Haemophilia : the official journal of the World Federation of Hemophilia.

A prospective registry of European haemophilia B patients receiving nonacog alfa, recombinant human factor IX, for usual use

M. Makris, A. Hassoun, A. Tagliaferri, 2012, Haemophilia : the official journal of the World Federation of Hemophilia.

The diagnosis and management of von Willebrand disease: a United Kingdom Haemophilia Centre Doctors Organization guideline approved by the British Committee for Standards in Haematology

R. Tait, M. Laffan, D. Keeling, 2014, British journal of haematology.

Heparin pretreatment does not alter heparin requirements during cardiopulmonary bypass.

D. Keeling, R. Evans, M. Sinclair, 2001, British journal of anaesthesia.

Guidelines on the investigation and management of venous thrombosis at unusual sites

D. Perry, T. Baglin, M. Makris, 2012, British journal of haematology.

Optimal loading dose of warfarin for the initiation of oral anticoagulation.

D. Nunan, R. Perera, N. Roberts, 2012, The Cochrane database of systematic reviews.

The Incidence of Factor VIII and Factor IX Inhibitors in the Hemophilia Population of the UK and Their Effect on Subsequent Mortality, 1977–991*

S. Darby, P. Giangrande, P. Collins, 2006 .

Inherited coagulation disorders.

D. Keeling, 2001, Clinical medicine.

Acquired haemophilia A in the UK: a two year national surveillance study by UK Haemophilia Centre Doctors’ Organisation Short title: Acquired haemophilia in the UK

T. Baglin, P. Collins, G. Dolan, 2006 .

Achievement of immune tolerance in a patient with haemophilia B and inhibitory antibodies, complicated by an anaphylactoid reaction

P. Giangrande, S. Misbah, D. Keeling, 2007, Haemophilia : the official journal of the World Federation of Hemophilia.

Activated prothrombin complex concentrate for the prevention of dabigatran‐ associated bleeding

D. Keeling, H. Wong, 2014, British journal of haematology.

Brain haemorrhage in five infants with coagulopathy

P. Anslow, D. Keeling, M. McShane, 2003, Archives of disease in childhood.

Effect of age on factor IX levels in symptomatic carriers of Haemophila B Leyden

D. Keeling, C. Hildyard, 2015, British journal of haematology.

Guidelines on oral anticoagulation (warfarin): third edition – 2005 update

H G Watson, T. Baglin, H. Watson, 2006, British journal of haematology.

Next‐generation sequencing for the diagnosis of MYH9‐RD: Predicting pathogenic variants

Sri V. V. Deevi, Nicholas S. Gleadall, K. Stirrups, 2019, Human mutation.

Next‐generation sequencing for the diagnosis ofMYH9‐RD

Sri V. V. Deevi, K. Stirrups, W. Ouwehand, 2019 .

Whole-genome sequencing of a sporadic primary immunodeficiency cohort

William J. Astle, Sri V. V. Deevi, Kenneth G. C. Smith, 2020, Nature.

Guidelines on the investigation and management of antiphospholipid syndrome

Ian Mackie, I. Greer, M. Greaves, 2012, British journal of haematology.

Normal d-dimer levels do not exclude the diagnosis of cerebral venous sinus thrombosis

K. Talbot, D. Keeling, M. Wright, 2002, Journal of Neurology.

Clinical guidelines for testing for heritable thrombophilia

Elaine Gray, Ian Mackie, Beverley J Hunt, 2010, British journal of haematology.

Role of / h-glycoprotein I and antiphospholipid antibodies in activation of protein C in vitro

D. Isenberg, D. Keeling, Machin, 2022 .

Haemolytic uraemic syndrome after bone marrow transplantation: an adverse effect of total body irradiation?

H. Prentice, D. Keeling, P. Sweny, 1988, Bone marrow transplantation.

The acute management of haemorrhage, surgery and overdose in patients receiving dabigatran

G. Benson, T. Baglin, L. Green, 2013, Emergency Medicine Journal.

Combined oral contraceptives and the risk of myocardial infarction

D. Keeling, 2003, Annals of medicine.

Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension

Fengyuan Hu, Kevin Rue-Albrecht, Patrick Deegan, 2017, Circulation.

Sagittal sinus thrombosis in a teenager: homocystinuria associated with reversible antithrombin deficiency.

D. Keeling, M. Pike, J. Leonard, 2002, Developmental medicine and child neurology.

Spontaneous intracranial bleeding in two patients with congenital afibrinogenaemia and the role of replacement therapy

R. Parameswaran, J. Dickinson, D. Keeling, 2000, Haemophilia : the official journal of the World Federation of Hemophilia.

Sezary cell-like leukemia: a distinct type of mature T cell malignancy.

D. Catovsky, E. Matutes, C. Scott, 1990, Leukemia.

A family with type 2M VWD with normal VWF:RCo but reduced VWF:CB and a M1761K mutation in the A3 domain

D. Keeling, P. Bignell, R. Marr, 2012, Haemophilia : the official journal of the World Federation of Hemophilia.

Optimal loading dose for the initiation of warfarin: a systematic review

R. Perera, C. Heneghan, A. Ward, 2010, BMC cardiovascular disorders.

How to interpret a prolonged prothrombin time or activated partial thromboplastin time.

D. Keeling, M. Desborough, 2013, British journal of hospital medicine.

Management of an uncommon form of type 2M VWD: a single centre experience

D. Keeling, P. Bignell, N. Curry, 2016 .

Pulmonary embolus in Glanzmann’s thrombasthenia treated with warfarin

D. Keeling, M. Seretny, E. Miller, 2008, Haemophilia : the official journal of the World Federation of Hemophilia.

Prediction of Bleeding Risk in Patients on Extended Oral Anticoagulation for Venous Thromboembolism

S. Kahn, D. Anderson, P. Wells, 2016 .

Efficacy of Warfarin Reversal in Orthopedic Trauma Surgery Patients

K. Willett, D. Keeling, J. Pusey, 2007, Journal of orthopaedic trauma.

The diagnosis and management of factor VIII and IX inhibitors: a guideline from the United Kingdom Haemophilia Centre Doctors Organisation

R. Liesner, C. Hay, D. Keeling, 2006, British journal of haematology.

Genetic Predisposition to Bleeding during Oral Anticoagulant Therapy: Evidence for Common Founder Mutations (FIXVal-10 and FIXThr-10) and an Independent CpG Hotspot Mutation (FIXThr-10)

B. Lämmle, J. Oldenburg, B. Konkle, 2001, Thrombosis and Haemostasis.

Switching between full‐length and B‐domain‐deleted factor VIII and the risk of inhibitors

D. Keeling, 2006, Haemophilia : the official journal of the World Federation of Hemophilia.