I. Christiaans

发表

How to inform relatives at risk of hereditary diseases? A mixed‐methods systematic review on patient attitudes

E. Smets, L. M. Heuvel, J. Tintelen, 2019, Journal of genetic counseling.

Targeted sequence capture and GS-FLX Titanium sequencing of 23 hypertrophic and dilated cardiomyopathy genes: implementation into diagnostics

F. Baas, R. L. Lekanne Deprez, N. Hofman, 2013, Journal of Medical Genetics.

Atlas of the clinical genetics of human dilated cardiomyopathy.

Karen S. Frese, R. Bellazzi, M. Bolognesi, 2014, European heart journal.

Gene-specific increase in the energetic cost of contraction in hypertrophic cardiomyopathy caused by thick filament mutations.

A. van Rossum, A. Wilde, A. Lammertsma, 2014, Cardiovascular research.

Large next-generation sequencing gene panels in genetic heart disease: challenges in clinical practice

M. Alders, I. Christiaans, O. Mook, 2019, Netherlands Heart Journal.

by thick filament mutations

A. Lammertsma, A. Rossum, P. Knaapen, 2014 .

Founder mutations in hypertrophic cardiomyopathy patients in the Netherlands

A. Wilde, P. Postema, M. Mannens, 2010, Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation.

Lamin A/C mutation is independently associated with an increased risk of arterial and venous thromboembolic complications.

A. Zwinderman, Y. Pinto, A. Wilde, 2013, International journal of cardiology.

Human Genetics of Cardiomyopathies

A. Wilde, I. Christiaans, A. Vermeer, 2016 .

Phospholamban R14del mutation in patients diagnosed with dilated cardiomyopathy or arrhythmogenic right ventricular cardiomyopathy: evidence supporting the concept of arrhythmogenic cardiomyopathy

R. Hauer, H. Calkins, D. J. Veldhuisen, 2012, European journal of heart failure.

Risk stratification and subclinical phenotyping of dilated and/or arrhythmogenic cardiomyopathy mutation-positive relatives: CVON eDETECT consortium

M. P. van den Berg, F. Asselbergs, T. V. van Veen, 2021, Netherlands Heart Journal.

Transthyretin amyloidosis: a phenocopy of hypertrophic cardiomyopathy

A. Wilde, M. Mannens, I. Christiaans, 2017, Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis.

A tailored approach towards informing relatives at risk of inherited cardiac conditions: study protocol for a randomised controlled trial

E. Smets, A. Baas, J. P. van Tintelen, 2019, BMJ Open.

Large next-generation sequencing gene panels in genetic heart disease: yield of pathogenic variants and variants of unknown significance

M. Alders, I. Christiaans, O. Mook, 2019, Netherlands Heart Journal.

The yield of risk stratification for sudden cardiac death in hypertrophic cardiomyopathy myosin-binding protein C gene mutation carriers: focus on predictive screening.

D. Atsma, G. Bonsel, Y. Pinto, 2010, European heart journal.

Risk stratification for sudden cardiac death in hypertrophic cardiomyopathy: Dutch cardiologists and the care of mutation carriers

G. Bonsel, E. Smets, I. M. Langen, 2009 .

Long-Term Follow-Up Study on the Uptake of Genetic Counseling and Predictive DNA Testing in Inherited Cardiac Conditions

E. Smets, I. V. van Langen, J. P. van Tintelen, 2020, Circulation. Genomic and precision medicine.

Feasibility of an Assessment Tool for Children’s Competence to Consent to Predictive Genetic Testing: a Pilot Study

T. Grisso, J. V. van Goudoever, I. Christiaans, 2015, Journal of Genetic Counseling.

A genetic researcher’s devil’s dilemma: Warn relatives about their genetic risk or respect confidentiality agreements with research participants?

M. C. Ploem, I. Christiaans, E. Maeckelberghe, 2021, BMC medical ethics.

Incidence and predictors of implantable cardioverter-defibrillator therapy and its complications in idiopathic ventricular fibrillation patients.

P. Doevendans, P. Postema, A. Wilde, 2019, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Ebstein anomaly associated with left ventricular noncompaction: An autosomal dominant condition that can be caused by mutations in MYH7

B. Mulder, B. Keavney, A. Postma, 2013, American journal of medical genetics. Part C, Seminars in medical genetics.

Penetrance of Hypertrophic Cardiomyopathy in Children Who Are Mutation Positive

A. Wilde, N. Blom, I. Christiaans, 2017, The Journal of pediatrics.

Mortality risk of untreated myosin-binding protein C-related hypertrophic cardiomyopathy: insight into the natural history.

J. Tijssen, A. Wilde, F. T. ten Cate, 2011, Journal of the American College of Cardiology.

Ventricular fibrillation in MYH7-related hypertrophic cardiomyopathy before onset of ventricular hypertrophy.

A. Wilde, I. V. van Langen, I. Christiaans, 2009, Heart rhythm.

Heritability in genetic heart disease: the role of genetic background

A. Moss, Y. Pinto, A. Wilde, 2019, Open Heart.

Heritability in genetic heart disease

A. Moss, Y. Pinto, A. Wilde, 2019 .

Reclassification of a likely pathogenic Dutch founder variant in KCNH2; implications of reduced penetrance

T. Koopmann, C. Bezzina, A. Wilde, 2022, bioRxiv.

Genetic Evaluation in a Cohort of 126 Dutch Pulmonary Arterial Hypertension Patients

J. P. van Tintelen, I. Christiaans, H. Bogaard, 2020, Genes.

GENCOR: a national registry for patients and families suffering from a familial heart disease in the Netherlands.

Y. Pinto, A. Wilde, J. P. van Tintelen, 2006, Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation.

Obesity Cardiovascular Disease and the Failure of Public Health Education

S. Boekholdt, H. Katus, C. Bezzina, 2022 .

The patient with hypertrophic cardiomyopathy has a family

A. Wilde, I. Christiaans, 2010, Heart.

Dilation of the Aorta Ascendens Forms Part of the Clinical Spectrum of HCN4 Mutations.

A. Wilde, S. Boekholdt, H. Katus, 2016, Journal of the American College of Cardiology.

Effect of Ascertainment Bias on Estimates of Patient Mortality in Inherited Cardiac Diseases

A. Wilde, M. P. van den Berg, M. Ackerman, 2018, Circulation. Genomic and precision medicine.

Germline SMARCB1 mutation predisposes to multiple meningiomas and schwannomas with preferential location of cranial meningiomas at the falx cerebri

F. Baas, I. Christiaans, P. V. D. Munckhof, 2011, neurogenetics.

The need to continue screening for hypertrophic cardiomyopathy after adolescence.

A. Wilde, I. Christiaans, A. Vermeer, 2015, The American journal of cardiology.

Genetic Evaluation of A Nation-Wide Dutch Pediatric DCM Cohort: The Use of Genetic Testing in Risk Stratification

N. Blom, D. Barge-Schaapveld, A. Baas, 2022, Circulation. Genomic and precision medicine.

BIO FOr CARE: biomarkers of hypertrophic cardiomyopathy development and progression in carriers of Dutch founder truncating MYBPC3 variants—design and status

A. Wilde, R. D. de Boer, F. Asselbergs, 2021, Netherlands Heart Journal.

Lymphedema as first clinical presentation of Cantu Syndrome: reversed phenotyping after identification of gain-of-function variant in ABCC9

C. Nichols, M. Alders, I. Christiaans, 2022, European Journal of Human Genetics.

Monday, 27 August 2012

V. V. Ivanenko, E. A. Medvedeva, Michail I. Papafaklis, 2012 .

A novel alpha-tropomyosin mutation associates with dilated and non-compaction cardiomyopathy and diminishes actin binding.

A. Moorman, A. Wilde, R. L. Lekanne Deprez, 2013, Biochimica et biophysica acta.

Shared genetic pathways contribute to risk of hypertrophic and dilated cardiomyopathies with opposite directions of effect

P. Elliott, P. Matthews, D. O’Regan, 2020, Nature Genetics.

Large scale genome-wide association analyses identify novel genetic loci and mechanisms in hypertrophic cardiomyopathy

Kevin Knight, D. O’Regan, Y. Pinto, 2023, medRxiv.

Lack of evidence for a causal role of CALR3 in monogenic cardiomyopathy

R. Hofstra, R. Oldenburg, R. L. Lekanne Deprez, 2018, European Journal of Human Genetics.

Hypertrophic remodelling in cardiac regulatory myosin light chain (MYL2) founder mutation carriers.

H. Smeets, H. Brunner, A. Paulussen, 2016, European heart journal.

How to inform at‐risk relatives? Attitudes of 1379 Dutch patients, relatives, and members of the general population

I. Christiaans, W. V. van Zelst-Stams, F. Willeboordse, 2019, Journal of genetic counseling.

A tailored approach to informing relatives at risk of inherited cardiac conditions: results of a randomised controlled trial

A. Baas, J. P. van Tintelen, I. Christiaans, 2021, European Journal of Human Genetics.

A tailored approach to informing relatives at risk of inherited cardiac conditions: results of a randomised controlled trial

E. Smets, A. Baas, J. P. van Tintelen, 2021, European Journal of Human Genetics.

Germline SMARCB1 mutation predisposes to multiple meningiomas and schwannomas with preferential location of cranial meningiomas at the falx cerebri

F. Baas, I. Christiaans, S. Kenter, 2012, neurogenetics.

Informing relatives at risk of inherited cardiac conditions: experiences and attitudes of healthcare professionals and counselees

E. Smets, A. Baas, L. Henneman, 2019, European Journal of Human Genetics.

Hypertrophic cardiomyopathy: towards an optimal strategy

I. Christiaans, 2010 .

Uptake of genetic counselling and predictive DNA testing in hypertrophic cardiomyopathy

G. Bonsel, A. Wilde, I. M. Langen, 2008, European Journal of Human Genetics.

Germline SMARCB1 mutation and somatic NF2 mutations in familial multiple meningiomas

F. Baas, P. van den Munckhof, I. Christiaans, 2010, Journal of Medical Genetics.

A mutation update for the FLNC gene in myopathies and cardiomyopathies

S. Heymans, H. Brunner, F. Asselbergs, 2020, Human mutation.

Risk stratification for sudden cardiac death in hypertrophic cardiomyopathy: systematic review of clinical risk markers.

G. Bonsel, A. Wilde, P. Elliott, 2010, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Risk stratification in hypertrophic cardiomyopathy

Link, I. Christiaans, Link, 2010 .

The role of renin–angiotensin–aldosterone system polymorphisms in phenotypic expression of MYBPC3-related hypertrophic cardiomyopathy

A. Wilde, C. Bezzina, M. Tanck, 2012, European Journal of Human Genetics.

TGFβ‐inducible early gene‐1 (TIEG1) mutations in hypertrophic cardiomyopathy

W. Edwards, A. Wilde, M. Ackerman, 2012, Journal of cellular biochemistry.

TGFß-Inducible Early Gene-1 (TIEG1): A Novel Hypertrophic Cardiomyopathy- Susceptibility Gene

A. Wilde, S. Ommen, J. Bos, 2010 .

Clinical assessment of the development of hypertrophic cardiomyopathy by cardiovascular magnetic resonance imaging

A. Wilde, M. Heymans, I. Christiaans, 2013 .

Chapter 3 The role of renin-angiotensin-aldosterone system polymorphisms in phenotypic expression of MYBPC 3-related hypertrophic cardiomyopathy

A. Wilde, C. Bezzina, M. Tanck, 2012 .

Quality of life and psychological distress in hypertrophic cardiomyopathy mutation carriers: A cross‐sectional cohort study

G. Bonsel, A. Wilde, E. Smets, 2009, American journal of medical genetics. Part A.

Outcome in Phospholamban R14del Carriers: Results of a Large Multicentre Cohort Study

R. Hauer, A. Zwinderman, Y. Pinto, 2014, Circulation. Cardiovascular genetics.

Genetic analysis in 418 index patients with idiopathic dilated cardiomyopathy: overview of 10 years' experience

Y. Pinto, A. Wilde, F. Asselbergs, 2013, European journal of heart failure.

Gender‐specific differences in major cardiac events and mortality in lamin A/C mutation carriers

A. Zwinderman, Y. Pinto, E. Arbustini, 2013, European journal of heart failure.

HCN4 mutations in multiple families with bradycardia and left ventricular noncompaction cardiomyopathy.

R. Redon, Y. Pinto, A. Wilde, 2014, Journal of the American College of Cardiology.

Manifest disease, risk factors for sudden cardiac death, and cardiac events in a large nationwide cohort of predictively tested hypertrophic cardiomyopathy mutation carriers: determining the best cardiological screening strategy.

R. Hauer, D. Atsma, G. Bonsel, 2011, European heart journal.

International External Validation Study of the 2014 European Society of Cardiology Guidelines on Sudden Cardiac Death Prevention in Hypertrophic Cardiomyopathy (EVIDENCE-HCM)

A. Keren, E. Arbustini, A. Wilde, 2017, Circulation.

Haplotype-sharing analysis implicates chromosome 7q36 harboring DPP6 in familial idiopathic ventricular fibrillation.

P. Postema, K. Zeppenfeld, K. Koch, 2009, American journal of human genetics.

The never ending story of risk stratification for sudden death in hypertrophic cardiomyopathy.

A. Wilde, I. Christiaans, 2011, The American journal of cardiology.

Untargeted Metabolomics Identifies Potential Hypertrophic Cardiomyopathy Biomarkers in Carriers of MYBPC3 Founder Variants

R. D. de Boer, K. Wagner, N. Wagner, 2023, International journal of molecular sciences.

Detailed characterization of familial idiopathic ventricular fibrillation linked to the DPP6 locus.

A. Wilde, P. Postema, H. Tan, 2016, Heart rhythm.

Obtaining insurance after DNA diagnostics: a survey among hypertrophic cardiomyopathy mutation carriers

G. Bonsel, A. Wilde, E. Smets, 2010, European Journal of Human Genetics.

Genetic counseling and cardiac care in predictively tested hypertrophic cardiomyopathy mutation carriers: The patients' perspective

G. Bonsel, A. Wilde, E. Smets, 2009, American journal of medical genetics. Part A.

Clinical utility gene card for: hypertrophic cardiomyopathy (type 1–14)

Perry M Elliott, Y. Pinto, A. Wilde, 2011, European Journal of Human Genetics.

Carriers of the hypertrophic cardiomyopathy MYBPC3 mutation are characterized by reduced myocardial efficiency in the absence of hypertrophy and microvascular dysfunction

A. Wilde, M. Lubberink, A. Lammertsma, 2011, European journal of heart failure.

Founder mutations in the Netherlands: familial idiopathic ventricular fibrillation and DPP6

A. Wilde, P. Postema, K. Zeppenfeld, 2011, Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation.

Quality of Life in Young Adult Patients with a Cardiogenetic Condition Receiving an ICD for Primary Prevention of Sudden Cardiac Death

A. Wilde, I. V. van Langen, I. Christiaans, 2015, Pacing and clinical electrophysiology : PACE.

Evaluation of polygenic score for hypertrophic cardiomyopathy in the general population and across clinical settings

D. O’Regan, Wenjia Bai, A. Marvao, 2023, medRxiv.

Penetrance and Prognosis of MYH7 Variant-Associated Cardiomyopathies: Results From a Dutch Multicenter Cohort Study.

R. D. de Boer, F. Asselbergs, R. L. Lekanne Deprez, 2023, JACC. Heart failure.

Genetic Burden of TNNI3K in Diagnostic Testing of Patients With Dilated Cardiomyopathy and Supraventricular Arrhythmias

P. Ellinor, S. Choi, S. Lubitz, 2023, Circulation. Genomic and precision medicine.

Circulating Acylcarnitines Associated with Hypertrophic Cardiomyopathy Severity: an Exploratory Cross-Sectional Study in MYBPC3 Founder Variant Carriers

R. D. de Boer, A. Baas, J. Jans, 2023, Journal of cardiovascular translational research.

[Hypertrophic cardiomyopathy].

A. van Rossum, R. D. de Boer, P. Elliott, 2019, Nederlands tijdschrift voor geneeskunde.

Quality of life and psychological distress in hypertrophic cardiomyopathy mutation carriers: A cross‐sectional cohort study

G. Bonsel, A. Wilde, E. Smets, 2009, American journal of medical genetics. Part A.

Sudden cardiac death in the young. What’s the rationale behind the irrationality in their surviving relatives?

I. Christiaans, 2013, European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology.

Understanding cardiac electrical phenotypes in the genomic era

A. Wilde, P. Lichtner, T. Koopmann, 2015 .

Risk stratification for sudden cardiac death in hypertrophic cardiomyopathy: systematic review of clinical risk markers.

G. Bonsel, A. Wilde, P. Elliott, 2010, Europace.

Clinical assessment of the development of hypertrophic cardiomyopathy by cardiovascular magnetic resonance imaging

A. Wilde, I. Christiaans, A. Houweling, 2013 .

Atlas of the clinical genetics of human dilated cardiomyopathy.

Karen S. Frese, R. Bellazzi, M. Bolognesi, 2014, European heart journal.

Ventricular fibrillation in MYH7-related hypertrophic cardiomyopathy before onset of ventricular hypertrophy.

I. V. van Langen, I. Christiaans, Ronald H. Lekanne dit Deprez, 2009, Heart rhythm.

Genetic basis of hypertrophic cardiomyopathy

S. Ommen, T. Spelsberg, I. Christiaans, 2010 .

The genetic basis of apparently idiopathic ventricular fibrillation: a retrospective overview

P. Postema, P. Volders, D. Barge-Schaapveld, 2023, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

Haplotype-sharing analysis implicates chromosome 7q36 harboring DPP6 in familial idiopathic ventricular fibrillation.

P. Postema, K. Zeppenfeld, K. Koch, 2009, American journal of human genetics.

Ebstein anomaly associated with left ventricular noncompaction: An autosomal dominant condition that can be caused by mutations in MYH7

B. Mulder, B. Keavney, A. Postma, 2013, American journal of medical genetics. Part C, Seminars in medical genetics.

Predicting personal cardiovascular disease risk based on family health history: Development of expert-based family criteria for the general population

I. V. van Langen, I. Christiaans, C. van der Werf, 2023, European Journal of Human Genetics.

Biallelic variants in POPDC2 cause a novel autosomal recessive syndrome presenting with cardiac conduction defects and variable hypertrophic cardiomyopathy

Gardar Sveinbjornsson, P. Postema, H. Hólm, 2024, medRxiv.

Multiple myocardial crypts on modified long-axis view are a specific finding in pre-hypertrophic HCM mutation carriers.

M. Heymans, I. Christiaans, T. Germans, 2012, European heart journal cardiovascular Imaging.

ESCAPE-HCM study: Evaluation of SCreening of Asymptomatic PatiEnts with Hypertrophic CardioMyopathy

I. Christiaans, L. Dijksman, E. Birnie, 2007, Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation.

Sudden cardiac death in the young. What’s the rationale behind the irrationality in their surviving relatives?

I. Christiaans, 2013, European journal of cardiovascular nursing : journal of the Working Group on Cardiovascular Nursing of the European Society of Cardiology.

Risk stratification for sudden cardiac death in hypertrophic cardiomyopathy: Dutch cardiologists and the care of mutation carriers

G. Bonsel, I. V. van Langen, I. Christiaans, 2009, Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation.