Ling-Chu Chang

发表

Inhibition of lipopolysaccharide-stimulated NO production by a novel synthetic compound CYL-4d in RAW 264.7 macrophages involving the blockade of MEK4/JNK/AP-1 pathway.

C. Tzeng, S. Kuo, Li‐Jiau Huang, 2007, Biochemical pharmacology.

DOCK1 Regulates Growth and Motility through the RRP1B-Claudin-1 Pathway in Claudin-Low Breast Cancer Cells

Wei‐Chao Chang, Ling-Chu Chang, Shih-Kai Chiang, 2019, Cancers.

The influence of acetylshikonin, a natural naphthoquinone, on the production of leukotriene B4 and thromboxane A2 in rat neutrophils.

S. Kuo, Li‐Jiau Huang, Ling-Chu Chang, 2009, European journal of pharmacology.

A novel microtubule inhibitor, MT3-037, causes cancer cell apoptosis by inducing mitotic arrest and interfering with microtubule dynamics.

Hui-Yi Lin, R. Chou, Wei‐Chien Huang, 2016, American journal of cancer research.

Long noncoding RNA HOTAIR promotes invasion of breast cancer cells through chondroitin sulfotransferase CHST15

Wei-Chung Cheng, Shu-Hsuan Liu, Shao-Chun Wang, 2019, International journal of cancer.

Inhibition of superoxide anion generation by CHS-111 via blockade of the p21-activated kinase, protein kinase B/Akt and protein kinase C signaling pathways in rat neutrophils.

S. Kuo, Li‐Jiau Huang, Chi-Sen Chang, 2009, European journal of pharmacology.

Blockade of cytosolic phospholipase A(2) and 5-lipoxygenase activation in neutrophils by a natural isoflavanquinone abruquinone A.

Sheng-Chih Chen, S. Kuo, Ling-Chu Chang, 2008, European journal of pharmacology.

Inhibition of nitric oxide production by the carbazole compound LCY-2-CHO via blockade of activator protein-1 and CCAAT/enhancer-binding protein activation in microglia.

S. Kuo, Li‐Jiau Huang, Chi-Sen Chang, 2008, Biochemical pharmacology.

Design and synthesis of new 2-arylnaphthyridin-4-ones as potent antitumor agents targeting tumorigenic cell lines.

Chi-Hung Huang, S. Kuo, Li‐Jiau Huang, 2015, European journal of medicinal chemistry.

Examination of the signal transduction pathways leading to activation of extracellular signal‐regulated kinase by formyl‐methionyl‐leucyl‐phenylalanine in rat neutrophils

Ling-Chu Chang, Jih P. Wang, 1999, FEBS letters.

Inhibition of formyl-methionyl-leucyl-phenylalanine-stimulated phospholipase D activation in rat neutrophils by the synthetic isoquinoline DMDI.

Ling-Chu Chang, Jih P. Wang, Chi‐Ming Chen, 2003, Biochimica et biophysica acta.

2-Benzyloxybenzaldehyde inhibits formyl-methionyl-leucyl-phenylalanine stimulation of phospholipase D activation in rat neutrophils.

S. Kuo, Li‐Jiau Huang, Ling-Chu Chang, 2002, Biochimica et biophysica acta.

Investigation of the cellular mechanism of inhibition of formyl-methionyl-leucyl-phenylalanine-induced superoxide anion generation in rat neutrophils by 2-benzyloxybenzaldehyde.

S. Kuo, Li‐Jiau Huang, Ling-Chu Chang, 2003, Biochemical pharmacology.

The blockade of formyl peptide-induced respiratory burst by 2',5'-dihydroxy-2-furfurylchalcone involves phospholipase D signaling in neutrophils

Ling-Chu Chang, Jih P. Wang, Chun-nan Lin, 2003, Naunyn-Schmiedeberg's Archives of Pharmacology.

A Dual Role of Heme Oxygenase-1 in Cancer Cells

Ling-Chu Chang, Shih-Kai Chiang, Shuen-Ei Chen, 2018, International journal of molecular sciences.

Cellular mechanisms of inhibition of superoxide anion generation in rat neutrophils by the synthetic isoquinoline DMDI.

Ling-Chu Chang, Jih P. Wang, S. Raung, 2002, European journal of pharmacology.

Inhibition by Magnolol of Formylmethionyl‐leucyl‐phenyl alanine‐induced Respiratory Burst in Rat Neutrophils

L. Tsao, Ling-Chu Chang, Jih P. Wang, 1999, The Journal of pharmacy and pharmacology.

Heme oxygenase-1 mediates BAY 11-7085 induced ferroptosis.

Wei‐Chao Chang, R. Chou, Ling-Chu Chang, 2018, Cancer letters.

Effects of glucocorticoids on Fas gene expression in bovine blood neutrophils.

Ling-Chu Chang, P. S. Weber, J. Burton, 2004, The Journal of endocrinology.

Unrestricted Feed Intake Induces β-Cell Death and Impairs Insulin Secretion in Broiler Breeder Hens

R. Walzem, Ling-Chu Chang, Shuen-Ei Chen, 2020, Animals : an open access journal from MDPI.

The Role of HO-1 and Its Crosstalk with Oxidative Stress in Cancer Cell Survival

Ling-Chu Chang, Shih-Kai Chiang, Shuen-Ei Chen, 2021, Cells.

Signaling mechanisms of inhibition of phospholipase D activation by CHS-111 in formyl peptide-stimulated neutrophils.

Li‐Jiau Huang, Chi-Sen Chang, Ling-Chu Chang, 2011, Biochemical pharmacology.

2-Benzyloxybenzaldehyde inhibits formyl peptide-stimulated increase in intracellular Ca2+ in neutrophils mainly by blocking Ca2+ entry

S. Kuo, Li‐Jiau Huang, L. Tsao, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

Design, Synthesis, Mechanisms of Action, and Toxicity of Novel 20(S)-Sulfonylamidine Derivatives of Camptothecin as Potent Antitumor Agents

Jai-Sing Yang, Y. Wu, S. Kuo, 2014, Journal of medicinal chemistry.

Activation of phosphoinositide 3-kinase and Src family kinase is required for respiratory burst in rat neutrophils stimulated with artocarpol A.

Hui-Yi Lin, Li‐Jiau Huang, L. Tsao, 2006, Biochemical pharmacology.

Inhibition of superoxide anion generation by YC-1 in rat neutrophils through cyclic GMP-dependent and -independent mechanisms.

S. Kuo, Ling-Chu Chang, Jih P. Wang, 2002, Biochemical pharmacology.

Growth-promoting function of the cGAS-STING pathway in triple-negative breast cancer cells

Shao-Chun Wang, Yuan-Liang Wang, Ling-Chu Chang, 2022, Frontiers in Oncology.

Structure-activity relationship study of pyridazine derivatives as glutamate transporter EAAT2 activators.

M. Glicksman, G. Cuny, Ling-Chu Chang, 2011, Bioorganic & medicinal chemistry letters.

Inhibition of formyl-methionyl-leucyl-phenylalanine-stimulated respiratory burst by cirsimaritin involves inhibition of phospholipase D signaling in rat neutrophils

Sheng-Chih Chen, S. Kuo, Ling-Chu Chang, 2002, Naunyn-Schmiedeberg's Archives of Pharmacology.

Design, synthesis and evaluation of antiproliferative activity of fluorinated betulinic acid.

Stephen J. Capuzzi, K. Lee, Ling-Chu Chang, 2019, Bioorganic & medicinal chemistry.

Cytotoxicity Produced by Silicate Nanoplatelets: Study of Cell Death Mechanisms

San-Yuan Huang, Jiang-Jen Lin, Ling-Chu Chang, 2020, Toxins.

857‐860Anti‐inflammatory Effect of Magnolol, Isolated from Magnolia officinalis, on A23187‐induced Pleurisy in Mice

T. Ho, Ling-Chu Chang, Jih P. Wang, 1995, The Journal of pharmacy and pharmacology.

Aptamer-guided targeting of the intracellular long-noncoding RNA HOTAIR.

Shao-Chun Wang, Yuan-Liang Wang, Ling-Chu Chang, 2021, American journal of cancer research.

Effect of bis(hydroxymethyl) alkanoate curcuminoid derivative MTH-3 on cell cycle arrest, apoptotic and autophagic pathway in triple-negative breast adenocarcinoma MDA-MB-231 cells: An in vitro study

Jai-Sing Yang, F. Tsai, S. Kuo, 2017, International journal of oncology.

Mechanisms of glucocorticoid‐induced down‐regulation of neutrophil L‐selectin in cattle: evidence for effects at the gene‐expression level and primarily on blood neutrophils

P. Saama, Ling-Chu Chang, G. Smith, 2004, Journal of leukocyte biology.

The newly synthesized 2-arylnaphthyridin-4-one, CSC-3436, induces apoptosis of non-small cell lung cancer cells by inhibiting tubulin dynamics and activating CDK1

Hui-Yi Lin, R. Chou, S. Kuo, 2015, Cancer Chemotherapy and Pharmacology.

Gene expression signatures in neutrophils exposed to glucocorticoids: a new paradigm to help explain "neutrophil dysfunction" in parturient dairy cows.

R. van Dorp, B. Earley, Ling-Chu Chang, 2005, Veterinary immunology and immunopathology.

Next-generation sequencing analysis reveals that MTH-3, a novel curcuminoid derivative, suppresses the invasion of MDA-MB-231 triple-negative breast adenocarcinoma cells

Jai-Sing Yang, F. Tsai, S. Kuo, 2021, Oncology reports.

EFHD2 contributes to non-small cell lung cancer cisplatin resistance by the activation of NOX4-ROS-ABCC1 axis

Shao-Chun Wang, Wei‐Chao Chang, Y. Sher, 2020, Redox biology.

Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease

M. Glicksman, Yuchen Lin, G. Cuny, 2015, The Journal of experimental medicine.

Small-molecule activator of glutamate transporter EAAT2 translation provides neuroprotection.

K. Seyb, M. Glicksman, Yuchen Lin, 2014, The Journal of clinical investigation.

New bis(hydroxymethyl) alkanoate curcuminoid derivatives exhibit activity against triple-negative breast cancer in vitro and in vivo.

Hui-Yi Lin, S. Kuo, Chang-Hai Tsai, 2017, European journal of medicinal chemistry.

EGFR modulates DNA synthesis and repair through Tyr phosphorylation of histone H4.

M. Hung, W. Xia, J. Hsu, 2014, Developmental cell.

Signal transduction pathways for activation of extracellular signal‐regulated kinase by arachidonic acid in rat neutrophils

Ling-Chu Chang, Jih P. Wang, L. C. Chang, 2001, Journal of leukocyte biology.

Dietary components as epigenetic-regulating agents against cancer

Ling-Chu Chang, Yung-Luen Yu, 2016, BioMedicine.

Discovery of 3-(4-bromophenyl)-6-nitrobenzo[1.3.2]dithiazolium ylide 1,1-dioxide as a novel dual cyclooxygenase/5-lipoxygenase inhibitor that also inhibits tumor necrosis factor-alpha production.

J. Chern, Chiung-Hua Huang, Ling-Chu Chang, 2010, Bioorganic & medicinal chemistry.

YC‐1 inhibits proliferation of breast cancer cells by down‐regulating EZH2 expression via activation of c‐Cbl and ERK

Hui-Yi Lin, R. Chou, S. Kuo, 2014, British journal of pharmacology.

Macrophage secretory IL-1β promotes docetaxel resistance in head and neck squamous carcinoma via SOD2/CAT-ICAM1 signaling

Wei‐Chao Chang, Yung-An Tsou, Ling-Chu Chang, 2022, JCI insight.

Expression of adenylyl cyclase isoforms in neutrophils.

Ling-Chu Chang, Jih P. Wang, Yi-Lee Lin, 2003, Biochimica et biophysica acta.

The Upstream Regulation of p38 Mitogen‐activated Protein Kinase Phosphorylation by Arachidonic Acid in Rat Neutrophils

Ling-Chu Chang, Jih P. Wang, 2000, The Journal of pharmacy and pharmacology.

contributed equally to this paper. Restored glial glutamate transporter EAAT2 function as a potential

M. Glicksman, Yuchen Lin, G. Cuny, 2015 .

Microarray analysis of gene expression in blood neutrophils of parturient cows.

G. J. Rosa, P. Coussens, Ling-Chu Chang, 2004, Physiological genomics.

DOCK1 Regulates Growth and Motility through the RRP1B-Claudin-1 Pathway in Claudin-Low Breast Cancer Cells

Wei‐Chao Chang, Ling-Chu Chang, Shih-Kai Chiang, 2019, Cancers.

Activation of p38 mitogen-activated protein kinase by formyl-methionyl-leucyl-phenylalanine in rat neutrophils.

Ling-Chu Chang, L. C. Chang, J. P. Wang, 2000, European journal of pharmacology.

Targeting 2-oxoglutarate dehydrogenase for cancer treatment.

M. Hung, Ling-Chu Chang, Shih-Kai Chiang, 2022, American journal of cancer research.

Inhibition of CDCP1 by 8‐isopentenylnaringenin synergizes with EGFR inhibitors in lung cancer treatment

Y. Sher, Ling-Chu Chang, Lu‐Hai Wang, 2023, Molecular oncology.