I. Hubatsch

发表

Determination of drug permeability and prediction of drug absorption in Caco-2 monolayers

P. Artursson, I. Hubatsch, E. Ragnarsson, 2007, Nature Protocols.

Beta- and gamma-di- and tripeptides as potential substrates for the oligopeptide transporter hPepT1.

K. Luthman, P. Artursson, D. Seebach, 2007, Journal of medicinal chemistry.

Structural basis for substrate specificity differences of horse liver alcohol dehydrogenase isozymes.

V Lamzin, P. Zwart, V. Lamzin, 2000, Biochemistry.

Human glutathione transferase A4-4: an alpha class enzyme with high catalytic efficiency in the conjugation of 4-hydroxynonenal and other genotoxic products of lipid peroxidation.

B. Mannervik, I. Hubatsch, M. Ridderström, 1998, The Biochemical journal.

Expression and purification of recombinant full-length NS3 protease-helicase from a new variant of Hepatitis C virus.

A. Poliakov, G. Stenberg, I. Hubatsch, 2002, Protein expression and purification.

Preparation and characterization of isozymes and isoforms of horse liver alcohol dehydrogenase.

I. Hubatsch, H. Adolph, P. Maurer, 1995, Journal of chromatography. A.

In vitro ADMET and physicochemical investigations of poly-N-methylated peptides designed to inhibit Abeta aggregation.

J. Johansson, P. Artursson, P. Bose, 2010, Bioorganic & medicinal chemistry.

Mechanism of the glutathione transferase-catalyzed conversion of antitumor 2-crotonyloxymethyl-2-cycloalkenones to GSH adducts.

B. Ganem, K. Houk, B. Mannervik, 2003, Journal of the American Chemical Society.

Inhibition of hepatitis C virus NS3 protease activity by product-based peptides is dependent on helicase domain.

A. Hallberg, A. Johansson, E. Åkerblom, 2001, Bioorganic & medicinal chemistry letters.

Ric c 1 and Ric c 3, the Allergenic 2S Albumin Storage Proteins of Ricinus communis: Complete Primary Structures and Phylogenetic Relationships

I. Hubatsch, R. Panzani, M. H. Bashir, 1997, International Archives of Allergy and Immunology.

Poorly soluble marketed drugs display solvation limited solubility.

Christel A. S. Bergström, Christel A S Bergström, C. Wassvik, 2007, Journal of medicinal chemistry.

Human glutathione transferase A4-4 crystal structures and mutagenesis reveal the basis of high catalytic efficiency with toxic lipid peroxidation products.

J. Tainer, B. Mannervik, I. Hubatsch, 1999, Journal of molecular biology.

A highly acidic tyrosine 9 and a normally titrating tyrosine 212 contribute to the catalytic mechanism of human glutathione transferase A4-4.

B. Mannervik, I. Hubatsch, 2001, Biochemical and biophysical research communications.

Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

N. M. Zaki, Christel A. S. Bergström, P. Artursson, 2011, Journal of pharmaceutical sciences.

DRUG DISCOVERY INTERFACE Structural Features Determining the Intestinal Epithelial Permeability and Efflux of Novel HIV-1 Protease Inhibitors

N. M. Zaki, L. Lazorova, U. Norinder, 2011 .

The cyclopentenone product of lipid peroxidation, 15-A(2t)-isoprostane (8-isoprostaglandin A(2)), is efficiently conjugated with glutathione by human and rat glutathione transferase A4-4.

J. Morrow, B. Mannervik, L. Roberts, 2002, Chemical research in toxicology.

Orally Active Antiviral Tripeptide Glycyl-Prolyl-Glycinamide Is Activated by CD26 (Dipeptidyl Peptidase IV) before Transport across the Intestinal Epithelium

P. Artursson, L. Lazorova, A. Vahlne, 2005, Antimicrobial Agents and Chemotherapy.