F. Schmidlin

发表

Tasquinimod triggers an early change in the polarization of tumor associated macrophages in the tumor microenvironment

T. Leanderson, Anders Olsson, J. Nakhlé, 2015, Journal of Immunotherapy for Cancer.

Discovery and structure-guided drug design of inhibitors of 11beta-hydroxysteroid-dehydrogenase type I based on a spiro-carboxamide scaffold.

E. Valeur, F. Schmidlin, Franck F. Lepifre, 2009, Bioorganic & medicinal chemistry letters.

Inverse agonist activity of pirenzepine at M2 muscarinic acetylcholine receptors

J. Gies, F. Schmidlin, L. Daeffler, 1999, British journal of pharmacology.

Interleukin-1beta induces bradykinin B2 receptor gene expression through a prostanoid cyclic AMP-dependent pathway in human bronchial smooth muscle cells.

C. Bertrand, J. Gies, F. Schmidlin, 1998, Molecular pharmacology.

Islet Endothelial Activation and Oxidative Stress Gene Expression Is Reduced by IL-1Ra Treatment in the Type 2 Diabetic GK Rat

G. Lacraz, N. Janel, M. Donath, 2009, PloS one.

Protease-activated receptors: how proteases signal to cells.

N. Bunnett, F. Schmidlin, 2001, Current opinion in pharmacology.

c-Cbl Mediates Ubiquitination, Degradation, and Down-regulation of Human Protease-activated Receptor 2*

G. Cottrell, N. Bunnett, F. Schmidlin, 2005, Journal of Biological Chemistry.

Hypercholesterolaemia, signs of islet microangiopathy and altered angiogenesis precede onset of type 2 diabetes in the Goto–Kakizaki (GK) rat

P. Halban, G. Lacraz, N. Janel, 2011, Diabetologia.

IL-1 antagonism reduces hyperglycemia and tissue inflammation in the type 2 diabetic GK rat

G. Lacraz, M. Donath, N. Kassis, 2009, Proceedings of the National Academy of Sciences.

LPS-induced lung inflammation is linked to increased epithelial permeability: role of MLCK

C. Bertrand, V. Théodorou, H. Eutamene, 2005, European Respiratory Journal.

Recycling and Resensitization of the Neurokinin 1 Receptor

M. Steinhoff, D. Roosterman, G. Cottrell, 2004, Journal of Biological Chemistry.

The third intracellular loop and carboxyl tail of neurokinin 1 and 3 receptors determine interactions with beta-arrestins.

D. Roosterman, N. Bunnett, F. Schmidlin, 2003, American journal of physiology. Cell physiology.

Heterologous regulation of trafficking and signaling of G protein-coupled receptors: β-Arrestin-dependent interactions between neurokinin receptors

N. Bunnett, F. Schmidlin, E. Grady, 2002, Proceedings of the National Academy of Sciences of the United States of America.

Dynamin and Rab5a-dependent Trafficking and Signaling of the Neurokinin 1 Receptor*

L. Slice, C. Sternini, N. Bunnett, 2001, The Journal of Biological Chemistry.

STX2171, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model.

H. Tutill, B. Potter, J. Day, 2013, Endocrine-related cancer.

PLA2 phosphorylation and cyclooxygenase-2 induction, through p38 MAP kinase pathway, is involved in the IL-1β-induced bradykinin B2 receptor gene transcription

C. Bertrand, J. Gies, F. Schmidlin, 2000, Naunyn-Schmiedeberg's Archives of Pharmacology.

Association Between Somatostatin Receptor Expression and Clinical Outcomes in Neuroendocrine Tumors

Xihong Lin, D. Christiani, S. Ogino, 2016, Pancreas.

Protease-Activated Receptor 2 Mediates Eosinophil Infiltration and Hyperreactivity in Allergic Inflammation of the Airway1

K. Dabbagh, C. Bertrand, N. Bunnett, 2002, The Journal of Immunology.

Protease-Activated Receptor 2 Mediates Eosinophil Infiltration and Hyperreactivity in Allergic Inflammation of the Airway 1

K. Dabbagh, C. Bertrand, N. Bunnett, 2002 .

Expression and function of proteinase-activated receptor 2 in human bronchial smooth muscle.

N. Martinet, N. Bunnett, F. Schmidlin, 2001, American journal of respiratory and critical care medicine.

Human bronchial smooth muscle cells in culture produce stem cell factor.

N. Frossard, F. Schmidlin, B. Gasser, 1999, The European respiratory journal.

Evidence of estrone-sulfate uptake modification in young and middle-aged rat prostate

Y. Allory, N. Sirab, A. Taille, 2015, The Journal of Steroid Biochemistry and Molecular Biology.

induced inflammation in mice

V. Lagente, J. Planquois, C. Bertrand, 2006 .

Evidence for in vitro expression of B1 receptor in the mouse trachea and urinary bladder

N. Frossard, G. Folkerts, J. Gies, 1999, British journal of pharmacology.

Interleukin-1 b Induces Bradykinin B 2 Receptor Gene Expression through a Prostanoid Cyclic AMP-Dependent Pathway in Human Bronchial Smooth Muscle Cells

C. Bertrand, J. Gies, F. Schmidlin, 1998 .

Glucocorticoids increase bradykinin B2 receptor gene transcription in cultured guinea-pig tracheal smooth muscle cells

J. Gies, F. Schmidlin, O. Kassel, 1999, Naunyn-Schmiedeberg's Archives of Pharmacology.

OXIDATIVE STRESS IS AN IMPORTANT COMPONENT OF AIRWAY INFLAMMATION IN MICE EXPOSED TO CIGARETTE SMOKE OR LIPOPOLYSACCHARIDE

V. Lagente, J. Planquois, C. Bertrand, 2008, Clinical and experimental pharmacology & physiology.

Effect of WIN 64338, a B2 bradykinin receptor antagonist on guinea‐pig tracheal smooth muscle cells in culture

J. Gies, F. Schmidlin, Y. Landry, 1998, Fundamental & clinical pharmacology.

Glucocorticoids inhibit the bradykinin B2 receptor increase induced by interleukin-1beta in human bronchial smooth muscle cells.

J. Gies, F. Schmidlin, Y. Landry, 1998, European journal of pharmacology.

Bradykinin B2 receptors mediate contraction in the normal and inflamed human gallbladder in vitro.

C. Figueroa, R. De Giorgio, N. Bunnett, 2003, Gastroenterology.

Rab5a and rab11a mediate agonist-induced trafficking of protease-activated receptor 2.

D. Roosterman, N. Bunnett, F. Schmidlin, 2003, American journal of physiology. Cell physiology.

Rab 5 a and rab 11 a mediate agonist-induced trafficking of protease-activated receptor 2

D. Roosterman, N. Bunnett, F. Schmidlin, 2003 .

Up- and down-regulation by glucocorticoids of the constitutive expression of the mast cell growth factor stem cell factor by human lung fibroblasts in culture.

N. Frossard, F. de Blay, F. Schmidlin, 1998, Molecular pharmacology.

IL1-β modulates Bradykinin B2 receptors expression through prostaglandins pathway in human bronchial smooth muscle cells in culture (HBSMC)

J. Gies, F. Schmidlin, Y. Landry, 1998 .

Discovery and structure-activity relationships of pentanedioic acid diamides as potent inhibitors of 11beta-hydroxysteroid dehydrogenase type I.

E. Valeur, F. Schmidlin, Franck F. Lepifre, 2009, Bioorganic & medicinal chemistry letters.

Somatostatin receptors in resected hepatocellular carcinoma: status and correlation with markers of poor prognosis

C. Desbois-Mouthon, D. Wendum, F. Schmidlin, 2017, Histopathology.

Tasquinimod modulates tumor-infiltrating myeloid cells and improves the antitumor immune response to PD-L1 blockade in bladder cancer

J. Nakhlé, P. Plas, A. Bauchet, 2016, Oncoimmunology.

Protease-activated receptor 2: activation, signalling and function.

G. Cottrell, N. Bunnett, F. Schmidlin, 2003, Biochemical Society transactions.

Structure-based design of 7-azaindole-pyrrolidine amides as inhibitors of 11β-hydroxysteroid dehydrogenase type I.

D. Musil, E. Valeur, F. Schmidlin, 2010, Bioorganic & medicinal chemistry letters.

Involvement of MMP-12 and phosphodiesterase type 4 in cigarette smoke-induced inflammation in mice

V. Lagente, J. Planquois, C. Bertrand, 2006, European Respiratory Journal.

STX2171, a 17b-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model

H. Tutill, B. Potter, J. Day, 2013 .

Mechanisms of initiation and termination of signalling by neuropeptide receptors: a comparison with the proteinase-activated receptors.

N. Bunnett, F. Schmidlin, E. Grady, 2000, Biochemical Society Transactions.