Liang Ma

发表

In silico identification and experimental validation of diuresis compounds from Euphorbia lathyris for potential UT-B inhibitors

L. Ouyang, Dahong Yao, Jiming Wu, 2016 .

Synthesis and Antiangiogenic Activity of Novel Gambogic Acid Derivatives

Tao Chen, Liang Ma, Rong-hong Zhang, 2012, Molecules.

Structural modification of honokiol, a biphenyl occurring in Magnolia officinalis: the evaluation of honokiol analogues as inhibitors of angiogenesis and for their cytotoxicity and structure-activity relationship.

Yuquan Wei, X. Liang, Shucai Li, 2011, Journal of medicinal chemistry.

Synthesis and biological evaluation of novel pyranochalcone derivatives as a new class of microtubule stabilizing agents.

X. Liang, Mingli Xiang, Liang Ma, 2013, European journal of medicinal chemistry.

A Novel Small Molecule, (E)-5-(2,4-di-tert-butyl-6-((2,4-dioxothiazolidin-5-ylidene)methyl)phenyl)-5′-methyl-7,7′-dimethoxy-4,4′-bibenzo[d][1,3]dioxole-5,5′-dicarboxylate (7k), Alleviates the Development of d-Galactosamine/Lipopolysaccharide-Induced Acute Liver Failure by Inhibiting Macrophage Infil

Liang Ma, Guangcheng Wang, Li-juan Chen, 2012, Journal of Pharmacology and Experimental Therapeutics.

Semi‐Synthesis and Biological Evaluation of 1,2,3‐Triazole‐Based Podophyllotoxin Congeners as Potent Antitumor Agents Inducing Apoptosis in HepG2 Cells

Yuquan Wei, Tao Chen, X. Liang, 2012, Archiv der Pharmazie.

Synthesis and Biological Evaluation of Novel Urea- and Guanidine-Based Derivatives for the Treatment of Obesity-Related Hepatic Steatosis

X. Liang, Liang Ma, Heying Pei, 2014, Molecules.

Calcium carbonate microspheres as carriers for the anticancer drug camptothecin

N. Klauke, A. Glidle, Yongkui Zhang, 2012 .

SKLB023 protects mice against acute liver injury by inhibiting proinflammatory cytokine production in both T cells and macrophages

Jia Yu, Liang Ma, Heying Pei, 2018, RSC advances.

In Vitro and In Vivo Primary Metabolic Characterization of F18, a Novel Histone Deacetylase-6 (HDAC6) Inhibitor, Using UHPLC–QqQ–MS/MS and Q-TOF–MS Methods

Liang Ma, Ming-hai Tang, Li-juan Chen, 2016, Chromatographia.

Synthesis and biological evaluation of 4-oxoquinoline-3-carboxamides derivatives as potent anti-fibrosis agents.

Yuquan Wei, Mingli Xiang, Liang Ma, 2014, Bioorganic & medicinal chemistry letters.

Synthesis, structure-activity relationships and biological evaluation of barbigerone analogues as anti-proliferative and anti-angiogenesis agents.

Yuquan Wei, F. Wang, Mingli Xiang, 2014, Bioorganic & medicinal chemistry letters.

Development and validation of a UPLC-MS/MS method for quantification of SKLB010, an investigational anti-inflammatory compound, and its application to pharmacokinetic studies in beagle dogs.

Liang Ma, Ming-hai Tang, Xianhuo Wang, 2011, Journal of pharmaceutical and biomedical analysis.

Synthesis, in vitro and in vivo evaluation of novel substituted N-(4-(2-(4-benzylpiperazin-1-yl)ethoxy)phenyl)-N-methyl-quinazolin-4-amines as potent antitumor agents.

F. Wang, Liang Ma, Ming-hai Tang, 2016, Bioorganic & medicinal chemistry letters.

Protective effect of SKLB010 against D-galactosamine/lipopolysaccharide-induced acute liver failure via nuclear factor-κB signaling pathway in macrophages.

Liang Ma, A. Peng, Li-juan Chen, 2014, International immunopharmacology.

Design, Synthesis, and Evaluation of in Vitro and in Vivo Anticancer Activity of 4-Substituted Coumarins: A Novel Class of Potent Tubulin Polymerization Inhibitors.

Chunyu Wang, F. Wang, Liang Ma, 2016, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of a series of pyrano chalcone derivatives containing indole moiety as novel anti-tubulin agents.

Yuquan Wei, X. Liang, F. Wang, 2014, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of novel millepachine derivatives as a new class of tubulin polymerization inhibitors.

Mingli Xiang, F. Wang, Liang Ma, 2014, Journal of medicinal chemistry.

Design, synthesis, and structure-activity relationship studies of novel millepachine derivatives as potent antiproliferative agents.

Yuquan Wei, X. Liang, Liang Ma, 2012, European journal of medicinal chemistry.

Synthesis, activity, and docking study of phenylthiazole acids as potential agonists of PPARγ

Liang Ma, Taijin Wang, Min Shi, 2016, Drug design, development and therapy.

Scaffold-based design of xanthine as highly potent inhibitors of DPP-IV for improving glucose homeostasis in DIO mice

Yuquan Wei, Mingli Xiang, Liang Ma, 2015, Molecular diversity.

SKLB023 Blocks Joint Inflammation and Cartilage Destruction in Arthritis Models via Suppression of Nuclear Factor-Kappa B Activation in Macrophage

Mingli Xiang, Liang Ma, Heying Pei, 2013, PloS one.

(Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione protects rats from carbon tetrachloride-induced liver injury and fibrogenesis.

Yuquan Wei, Liang Ma, Hao Zheng, 2012, World journal of gastroenterology.

Rapid separation and identification of major constituents in Pseudolarix kaempferi by ultra-performance liquid chromatography coupled with electrospray and quadrupole time-of-flight tandem mass spectrometry.

Liang Ma, Ming-hai Tang, A. Peng, 2009, Rapid communications in mass spectrometry : RCM.

(Z)-5-(4-methoxybenzylidene) thiazolidine-2, 4-dione ameliorates the adjuvant-induced arthritis via inhibiting the migration of macrophage and down-regulating the cytokine mRNA expression.

Yuquan Wei, Liang Ma, Youfu Luo, 2010, International immunopharmacology.

SKLB023 as an iNOS inhibitor alleviated liver fibrosis by inhibiting the TGF-beta/Smad signaling pathway

Qinhui Liu, Yanping Li, Liang Ma, 2018, RSC advances.

WITHDRAWN: (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione attenuates bleomycin-induced pulmonary fibrosis in rats

Yuquan Wei, Liang Ma, Youfu Luo, 2011 .

(Z)-5-(4-Methoxybenzylidene)thiazolidine-2,4-dione, a novel readily available and orally active glitazone, attenuates the bleomycin-induced pulmonary fibrosis in vivo.

Yuquan Wei, Liang Ma, Youfu Luo, 2011, Biological & pharmaceutical bulletin.

Synthesis and Biological Evaluation of 5‐Nitropyrimidine‐2,4‐dione Analogues as Inhibitors of Nitric Oxide and iNOS Activity

X. Liang, Liang Ma, Zhuang Yang, 2015, Chemical biology & drug design.

Synthesis and biological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives for the treatment of inflammatory diseases.

Yuquan Wei, Tao Chen, X. Liang, 2011, Journal of medicinal chemistry.

Identification of honokiol metabolites in rats by the method of stable isotope cluster technique and ultra-high performance liquid chromatography/quadrupole-time-of-flight mass spectrometry.

Yongkui Zhang, Hang Song, Shucai Li, 2013, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Synthesis, Activity, and Docking Study of Novel Phenylthiazole‐Carboxamido Acid Derivatives as FFA2 Agonists

Liang Ma, Heying Pei, P. Fu, 2016, Chemical biology & drug design.

Synthesis and biological activity of novel barbituric and thiobarbituric acid derivatives against non-alcoholic fatty liver disease.

Yuquan Wei, Tao Chen, Yi Ding, 2011, European journal of medicinal chemistry.

Synthesis and biological evaluation of novel pyrazoline derivatives as potent anti-inflammatory agents.

Liang Ma, Ming-hai Tang, Lijuan Chen, 2015, Bioorganic & medicinal chemistry letters.

Structural exploration, synthesis and pharmacological evaluation of novel 5-benzylidenethiazolidine-2,4-dione derivatives as iNOS inhibitors against inflammatory diseases.

X. Liang, Mingli Xiang, Liang Ma, 2015, European journal of medicinal chemistry.

Design, synthesis and biological evaluation of thiazole- and indole-based derivatives for the treatment of type II diabetes.

Yuquan Wei, Tao Chen, X. Liang, 2012, European journal of medicinal chemistry.

Inclusion complex of barbigerone with hydroxypropyl-β-cyclodextrin: preparation and in vitro evaluation.

Yuquan Wei, Yongkui Zhang, Hang Song, 2014, Carbohydrate polymers.

Separation of flavonoids from Millettia griffithii with high-performance counter-current chromatography guided by anti-inflammatory activity.

Liang Ma, Heying Pei, Huan Tang, 2015, Journal of separation science.

Identification of metabolites of honokiol in rat urine using 13C stable isotope labeling and liquid chromatography coupled with quadrupole time-of-flight tandem mass spectrometry.

Liang Ma, Ming-hai Tang, Lulu Cai, 2013, Journal of chromatography. A.

Discovery of (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione, a readily available and orally active glitazone for the treatment of concanavalin A-induced acute liver injury of BALB/c mice.

Yuquan Wei, Sheng-yong Yang, Gu He, 2010, Journal of medicinal chemistry.

Rational design, synthesis, and pharmacological properties of pyranochalcone derivatives as potent anti-inflammatory agents.

Yuquan Wei, X. Liang, Mingli Xiang, 2012, European journal of medicinal chemistry.

Synthesis and biological evaluation of novel dimethyl[1,1'-biphenyl]-2,2'-dicarboxylate derivatives containing thiazolidine-2,4-dione for the treatment of concanavalin A-induced acute liver injury of BALB/c mice.

Yuquan Wei, Tao Chen, Liang Ma, 2011, European journal of medicinal chemistry.

Synthesis and biological evaluation of 1, 2, 4‐oxadiazole derivatives as novel GPR119 agonists

Liang Ma, Lijuan Chen, Jinying Chen, 2017, Chemical biology & drug design.

Structure of the human gonadotropin-releasing hormone receptor GnRH1R reveals an unusual ligand binding mode

Yuquan Wei, Lin Cheng, Sheng-yong Yang, 2020, Nature Communications.

Synthesis and lipid-lowering evaluation of 3-methyl-1H-purine-2,6-dione derivatives as potent and orally available anti-obesity agents.

Liang Ma, Ming-hai Tang, Heying Pei, 2014, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of Novel Substituted 4‐Anilinoquinazolines as Antitumor Agents

Liang Ma, Zhuang Yang, Lijuan Chen, 2020, Chemical biology & drug design.

Targeted delivery of celastrol to renal interstitial myofibroblasts using fibronectin-binding liposomes attenuates renal fibrosis and reduces systemic toxicity.

Jinhang Zhang, Cuiyuan Huang, Qinhui Liu, 2020, Journal of controlled release : official journal of the Controlled Release Society.

Characterization of In Vivo Metabolites of a Potential Anti-obesity Compound, the 3-Methyl-1H-Purine-2,6-Dione Derivative C-11, Employing Ultra-High Performance Liquid Chromatography Coupled with Quadrupole Time-of-Flight Mass Spectrometry

Liang Ma, Ming-hai Tang, Neng Qiu, 2016, Chromatographia.

A novel agonist of PPAR-γ based on barbituric acid alleviates the development of non-alcoholic fatty liver disease by regulating adipocytokine expression and preventing insulin resistance.

Mingli Xiang, Liang Ma, Li-juan Chen, 2011, European journal of pharmacology.

Design, Synthesis, and Anti-Proliferative Evaluation of [1,1′-biphenyl]-4-ols as Inhibitor of HUVEC Migration and Tube Formation

Liang Ma, Lijuan Chen, Guangcheng Wang, 2012, Molecules.

Synthesis and biological evaluation of pyranoisoflavone derivatives as anti-inflammatory agents.

Yuquan Wei, Mingli Xiang, Liang Ma, 2014, Fitoterapia.

Discovery of Selective Histone Deacetylase 6 Inhibitors Using the Quinazoline as the Cap for the Treatment of Cancer.

F. Wang, Liang Ma, Zhuang Yang, 2016, Journal of medicinal chemistry.

Mixed micelles loaded with the 5-benzylidenethiazolidine-2,4-dione derivative SKLB023 for efficient treatment of non-alcoholic steatohepatitis

Jinhang Zhang, Qinhui Liu, Tong Wu, 2019, International journal of nanomedicine.

Synthesis and biological evaluation of 5-benzylidenepyrimidine-2,4,6(1H,3H,5H)-trione derivatives for the treatment of obesity-related nonalcoholic fatty liver disease.

Yuquan Wei, X. Liang, Mingli Xiang, 2012, Journal of medicinal chemistry.

Design, synthesis and biological evaluation of millepachine derivatives as a new class of tubulin polymerization inhibitors.

Yuquan Wei, Mingli Xiang, Liang Ma, 2013, Bioorganic & medicinal chemistry.

Synthesis and biological evaluation of diarylthiazole derivatives as antimitotic and antivascular agents with potent antitumor activity.

F. Wang, Chunlai Nie, Liang Ma, 2015, Bioorganic & medicinal chemistry.

Discovery of 5-methyl-2-(4-((4-(methylsulfonyl)benzyl)oxy)phenyl)-4-(piperazin-1-yl)pyrimidine derivatives as novel GRP119 agonists for the treatment of diabetes and obesity

Liang Ma, Linhong He, Jinying Chen, 2017, Molecular Diversity.

Scaffold-based design of xanthine as highly potent inhibitors of DPP-IV for improving glucose homeostasis in DIO mice

Yuquan Wei, Mingli Xiang, Liang Ma, 2015, Molecular Diversity.

Discovery of a Potent 9‐Deazaxanthine‐based Agent for the Treatment of Obesity‐Related Non‐alcoholic Fatty Liver Disease

Liang Ma, Heying Pei, Lijuan Chen, 2015, Chemical biology & drug design.

Synthesis and Evaluation of 5‐Benzylidenethiazolidine‐2,4‐dione Derivatives for the Treatment of Non‐Alcoholic Fatty Liver Disease

X. Liang, Liang Ma, Jinying Chen, 2012, Archiv der Pharmazie.

Therapeutic potential of a synthetic FABP4 inhibitor 8g on atherosclerosis in ApoE-deficient mice: the inhibition of lipid accumulation and inflammation

Liang Ma, Heying Pei, Lijuan Chen, 2016 .

Synthesis and Evaluation of Millepachine Amino Acid Prodrugs With Enhanced Solubility as Antitumor Agents

F. Wang, Liang Ma, Lijuan Chen, 2015, Chemical biology & drug design.

Discovery of a Potent 9‐Deazaxanthine‐based Agent for the Treatment of Obesity‐Related Non‐alcoholic Fatty Liver Disease

Liang Ma, Heying Pei, Lijuan Chen, 2015, Chemical biology & drug design.