E. Wijeratne

发表

Sesquiterpene quinones and related metabolites from Phyllosticta spinarum, a fungal strain endophytic in Platycladus orientalis of the Sonoran Desert.

A. Arnold, A. Gunatilaka, E. Wijeratne, 2008, Journal of natural products.

Dual Action Antifungal Small Molecule Modulates Multidrug Efflux and TOR Signaling

J. Heitman, A. Gingras, F. P. Roth, 2016, Nature chemical biology.

Combinatorial Mutasynthesis of Scrambled Beauvericins, Cyclooligomer Depsipeptide Cell Migration Inhibitors from Beauveria bassiana

I. Molnár, A. Gunatilaka, E. Wijeratne, 2009, Chembiochem : a European journal of chemical biology.

Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation.

Donna D. Zhang, A. Gunatilaka, E. Wijeratne, 2019, Cell chemical biology.

Uncovering biosynthetic potential of plant-associated fungi: effect of culture conditions on metabolite production by Paraphaeosphaeria quadriseptata and Chaetomium chiversii.

A. Gunatilaka, E. Wijeratne, P. Paranagama, 2007, Journal of natural products.

Cytotoxic and Antihaptotactic beauvericin analogues from precursor-directed biosynthesis with the insect pathogen Beauveria bassiana ATCC 7159.

I. Molnár, J. Zhan, A. Gunatilaka, 2007, Journal of natural products.

The anticancer activity of the fungal metabolite terrecyclic acid A is associated with modulation of multiple cellular stress response pathways

L. Whitesell, A. Gunatilaka, E. Wijeratne, 2005, Molecular Cancer Therapeutics.

Thielavialides A–E, Nor-Spiro-azaphilones, and a Bis-spiro-azaphilone from Thielavia sp. PA0001, An Endophytic Fungus Isolated from Aeroponically Grown Physalis alkekengi

R. Gruener, A. Gunatilaka, E. Wijeratne, 2014, Journal of natural products.

Phomapyrrolidones A-C, antitubercular alkaloids from the endophytic fungus Phoma sp. NRRL 46751.

S. Franzblau, A. Gunatilaka, E. Wijeratne, 2013, Journal of natural products.

Asperpyrone D and other metabolites of the plant-associated fungal strain Aspergillus tubingensis.

J. Zhan, A. Gunatilaka, E. Wijeratne, 2007, Phytochemistry.

Five new isocoumarins from Sonoran desert plant-associated fungal strains Paraphaeosphaeria quadriseptata and Chaetomium chiversii

A. Gunatilaka, E. Wijeratne, P. Paranagama, 2006 .

Withanolides from Aeroponically Grown Physalis peruviana and Their Selective Cytotoxicity to Prostate Cancer and Renal Carcinoma Cells.

T. Sayers, A. Brooks, P. Tewary, 2017, Journal of natural products.

Discovery of Potent 17β-Hydroxywithanolides for Castration-Resistant Prostate Cancer by High-Throughput Screening of a Natural Products Library for Androgen-Induced Gene Expression Inhibitors.

G. Paine-Murrieta, S. Felder, A. Gunatilaka, 2015, Journal of medicinal chemistry.

Structure-activity relationships for withanolides as inducers of the cellular heat-shock response.

S. Lindquist, S. Santagata, L. Whitesell, 2014, Journal of medicinal chemistry.

Non-covalent NRF2 Activation Confers Greater Cellular Protection than Covalent Activation.

Donna D. Zhang, A. Gunatilaka, E. Wijeratne, 2019, Cell chemical biology.

Ponicidin and oridonin are responsible for the antiangiogenic activity of Rabdosia rubescens, a constituent of the herbal supplement PC SPES.

L. Whitesell, E. Wijeratne, Guang-xiong Zhou, 2004, Journal of natural products.

Antimicrobial activity of some celastroloids and their derivatives

R. Guido, E. Wijeratne, G. Gunaherath, 2022, Medicinal Chemistry Research.

Semi-synthesis and cytotoxicity evaluation of pyrimidine, thiazole, and indole analogues of argentatins A–C from guayule (Parthenium argentatum) resin

I. Molnár, E. Wijeratne, Chandrashekhar Madasu, 2021, Medicinal Chemistry Research.

Betulinic acid, derived from the desert lavender Hyptis emoryi, attenuates paclitaxel-, HIV-, and nerve injury–associated peripheral sensory neuropathy via block of N- and T-type calcium channels

M. Khanna, R. Khanna, J. Streicher, 2018, Pain.

Physachenolide C is a Potent, Selective BET Inhibitor.

N. Horton, M. Clarkson, R. Fromme, 2022, Journal of medicinal chemistry.

1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain

R. Khanna, A. Gunatilaka, E. Wijeratne, 2020, Molecular Brain.

Structure Determination of Two New Monocillin I Derivatives

J. Zhan, A. Gunatilaka, E. Wijeratne, 2010, Natural product communications.

Stereo and Regioselective Microbial Reduction of the Clerodane Diterpene 3,12-Dioxo-15,16-epoxy-4-hydroxycleroda-13(16),14-diene

A. Gunatilaka, E. Wijeratne, M. A. Lima, 2014, Natural Product Communications.

Two new bioactive polyketides from Curvularia trifolii, an endolichenic fungus isolated from Usnea sp., in Sri Lanka

E. Wijeratne, P. Paranagama, K. Samanthi, 2015 .

Smardaesidins A-G, isopimarane and 20-nor-isopimarane diterpenoids from Smardaea sp., a fungal endophyte of the moss Ceratodon purpureus.

A. Arnold, J. U’Ren, A. Gunatilaka, 2011, Journal of natural products.

Microbial transformations of aryltetralone and aryltetralin lignans by Cunninghamella echinulata and Beauveria bassiana.

A. Gunatilaka, E. Wijeratne, Gisele B. Messiano, 2010, Journal of natural products.

Acidissimin, a New Limonoid from Limonia acidissima

P. Moeller, A. Gunatilaka, E. Wijeratne, 1989 .

Using the heat-shock response to discover anticancer compounds that target protein homeostasis.

S. Lindquist, J. Clardy, S. Kesari, 2011, ACS chemical biology.

A new anthraquinone and cytotoxic curvularins of a Penicillium sp. from the rhizosphere of Fallugia paradoxa of the Sonoran desert.

L. Pierson, H. Vanetten, J. Zhan, 2004, The Journal of antibiotics.

Cyathocaline, an azafluorenone alkaloid from cyathocalyx zeylanica

D. Kingston, Y. Tezuka, A. Gunatilaka, 1995 .

Biological activity of some coumarins from Sri Lankan Rutaceae.

G. Hofmann, D. Kingston, R. Johnson, 1994, Journal of natural products.

Aspochalasins I, J, and K: three new cytotoxic cytochalasans of Aspergillus flavipes from the rhizosphere of Ericameria laricifolia of the Sonoran Desert.

L. Pierson, H. Vanetten, A. Gunatilaka, 2004, Journal of natural products.

Functional characterization of the biosynthesis of radicicol, an Hsp90 inhibitor resorcylic acid lactone from Chaetomium chiversii.

Shuhao Wang, Shuhao Wang, Erin A. Maine, 2008, Chemistry & biology.

Biomimetic conversion of (-)-fusoxypyridone and (-)-oxysporidinone to (-)-sambutoxin: further evidence for the structure of the tricyclic pyridone alkaloid, (-)-fusoxypyridone.

A. Gunatilaka, E. Wijeratne, 2011, Bioorganic & medicinal chemistry letters.

Heptaketides from Corynespora sp. inhabiting the cavern beard lichen, Usnea cavernosa: first report of metabolites of an endolichenic fungus.

A. Arnold, A. Gunatilaka, E. Wijeratne, 2007, Journal of natural products.

An epigenetic modifier induces production of 3-(4-oxopyrano)-chromen-2-ones in Aspergillus sp. AST0006, an endophytic fungus of Astragalus lentiginosus.

A. Arnold, A. Gunatilaka, E. Wijeratne, 2020, Tetrahedron.

An epigenetic modifier induces production of (10'S)-verruculide B, an inhibitor of protein tyrosine phosphatases by Phoma sp. nov. LG0217, a fungal endophyte of Parkinsonia microphylla.

A. Arnold, A. Gunatilaka, E. Wijeratne, 2017, Bioorganic & medicinal chemistry.

Artabotrine: A novel bioactive alkaloid from Artabotrys zeylanicus

D. Kingston, A. Gunatilaka, E. Wijeratne, 1995 .

A dioxoaporphine and other alkaloids of two annonaceous plants of sri lanka

Y. Hatanaka, Y. Tezuka, E. Wijeratne, 1996 .

Antifungal activity, acid and sugar content in the wood apple (Limonia acidissima) and their relation to fungal development

N. Adikaram, E. Wijeratne, B. Bandara, 1989 .

17β-Hydroxywithanolides as Sensitizers of Renal Carcinoma Cells to Tumor Necrosis Factor-α Related Apoptosis Inducing Ligand (TRAIL) Mediated Apoptosis: Structure-Activity Relationships.

T. Sayers, A. Brooks, C. J. Henrich, 2017, Journal of medicinal chemistry.

Antifungal compounds from immature avocado fruit peel

N. Adikaram, E. Wijeratne, D. Ewing, 1992 .

10′-Deoxy-10′ α-hydroxyascochlorin, a New Cell Migration Inhibitor and Other Metabolites from Acremonium sp., a Fungal Endophyte in Ephedra trifurca

A. Arnold, A. Gunatilaka, E. Wijeratne, 2013 .

Chemical constituents of three rutaceae species from sri lanka

Y. Tezuka, A. Gunatilaka, E. Wijeratne, 1992 .

A new dihydroxanthenone from a plant-associated strain of the fungus Chaetomium globosum demonstrates anticancer activity.

L. Whitesell, A. Gunatilaka, E. Wijeratne, 2006, Bioorganic & medicinal chemistry.

Pulvinulin A, Graminin C, and cis-Gregatin B – New Natural Furanones from Pulvinula sp. 11120, a Fungal Endophyte of Cupressus arizonica

A. Arnold, A. Gunatilaka, E. Wijeratne, 2015, Natural product communications.

Oxaspirol B with p97 Inhibitory Activity and Other Oxaspirols from Lecythophora sp. FL1375 and FL1031, Endolichenic Fungi Inhabiting Parmotrema tinctorum and Cladonia evansii.

A. Arnold, J. U’Ren, A. Gunatilaka, 2016, Journal of natural products.

Two new antioxidant active polyketides from Penicillium citrinum, an endolichenic fungus isolated from Parmotrema species in Sri Lanka

E. Wijeratne, P. Paranagama, K. Samanthi, 2015 .

Geopyxins A-E, ent-kaurane diterpenoids from endolichenic fungal strains Geopyxis aff. majalis and Geopyxis sp. AZ0066: structure-activity relationships of geopyxins and their analogues.

A. Arnold, L. Whitesell, J. U’Ren, 2012, Journal of natural products.

Maximizing chemical diversity of fungal metabolites: biogenetically related Heptaketides of the endolichenic fungus Corynespora sp. (1).

A. Arnold, A. Gunatilaka, E. Wijeratne, 2010, Journal of natural products.

Bioactive secondary metabolites from an Endolichenic Fungus, Corynespora sp. inhabiting the Cavern beard Lichen, Usnea cavernosa

A. Arnold, A. Gunatilaka, E. Wijeratne, 2008 .

Biosynthesis of the cyclooligomer depsipeptide beauvericin, a virulence factor of the entomopathogenic fungus Beauveria bassiana.

I. Molnár, S. Stock, A. Gunatilaka, 2008, Chemistry & biology.

An isoform-selective PTP1B inhibitor derived from nitrogen-atom augmentation of radicicol.

B. Blagg, Donna D. Zhang, A. Gunatilaka, 2019, Biochemistry.

Functional Chromatography Reveals Three Natural Products that Target the Same Protein with Distinct Mechanisms of Action

Donna D. Zhang, Tongde Wu, J. L. La Clair, 2014, Chembiochem : a European journal of chemical biology.

Cytotoxic and Noncytotoxic Metabolites from Teratosphaeria sp. FL2137, a Fungus Associated with Pinus clausa.

A. Arnold, J. U’Ren, A. Gunatilaka, 2018, Journal of natural products.

Search for Hsp90 inhibitors with potential anticancer activity: isolation and SAR studies of radicicol and monocillin I from two plant-associated fungi of the Sonoran desert.

S. Faeth, L. Whitesell, A. Gunatilaka, 2006, Journal of natural products.

Isolation, optimization of production and structure-activity relationship studies of monocillin I, the cytotoxic constituent of Paraphaeosphaeria quadriseptata.

J. Takahashi, L. Whitesell, V. Bolzani, 2004, The Journal of antibiotics.

Production and Structural Diversification of Withanolides by Aeroponic Cultivation of Plants of Solanaceae: Cytotoxic and Other Withanolides from Aeroponically Grown Physalis coztomatl

Lijiang Xuan, E. Wijeratne, Wen-qiong Wang, 2022, Molecules.

Structure-Activity Relationships of Withanolides as Antiproliferative Agents for Multiple Myeloma: Comparison of Activity in 2D Models and a 3D Coculture Model.

E. Wijeratne, M. Cuendet, M. Issa, 2021, Journal of natural products.

Cytotoxic and other withanolides from aeroponically grown Physalis philadelphica.

T. Sayers, A. Brooks, P. Tewary, 2018, Phytochemistry.

Chlorinated Dehydrocurvularins and Alterperylenepoxide A from Alternaria sp. AST0039, a Fungal Endophyte of Astragalus lentiginosus.

A. Arnold, A. Gunatilaka, E. Wijeratne, 2017, Journal of natural products.

Cytotoxic constituents of Aspergillus terreus from the rhizosphere of Opuntia versicolor of the Sonoran Desert.

L. Whitesell, L. Pierson, H. Vanetten, 2003, Journal of natural products.

A Rhizosphere Fungus Enhances Arabidopsis Thermotolerance through Production of an HSP90 Inhibitor1

C. Queitsch, E. Vierling, L. Whitesell, 2007, Plant Physiology.

Cytotoxic and other metabolites of Aspergillus inhabiting the rhizosphere of Sonoran desert plants.

L. Pierson, H. Vanetten, J. Zhan, 2004, Journal of natural products.

Synthesis and biological evaluation of novobiocin analogues as potential heat shock protein 90 inhibitors.

L. Whitesell, A. Gunatilaka, E. Wijeratne, 2013, Bioorganic & medicinal chemistry.

Withaferin A Analogs That Target the AAA+ Chaperone p97.

Donna D. Zhang, Tongde Wu, A. Gunatilaka, 2015, ACS chemical biology.

Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins

R. Chari, T. Sayers, A. Brooks, 2021, Cancer Research.

(-)-Hardwickiic Acid and Hautriwaic Acid Induce Antinociception via Blockade of Tetrodotoxin-Sensitive Voltage-Dependent Sodium Channels.

M. Khanna, R. Khanna, J. Streicher, 2018, ACS chemical neuroscience.

Betulinic acid analogs inhibit N- and T-type voltage-gated calcium channels to attenuate nerve-injury associated neuropathic and formalin models of pain

E. Wijeratne, Leslie Gunatilaka, Aida Calderón-Rivera, 2023, Neurobiology of pain.

Cytotoxic Physalins from Aeroponically Grown Physalis acutifolia.

A. Gunatilaka, E. Wijeratne, F. Ranjbar, 2021, Journal of natural products.

Biomimetic synthesis of xuxuarines Eα and Eβ: Structure revision of Rzedowskia bistriterpenoids

V. Bolzani, N. Jacobsen, A. Gunatilaka, 2008 .

Globosumones A-C, cytotoxic orsellinic acid esters from the Sonoran desert endophytic fungus Chaetomium globosum.

S. Faeth, A. Gunatilaka, E. Wijeratne, 2005, Journal of natural products.

Antifungal constituents of Limonia acidissima.

N. Adikaram, E. Wijeratne, B. Bandara, 1988, Planta medica.

Microbial transformation of some triterpenoids of Guayule resin by Chaetomium sp.

E. Wijeratne, Chandrashekhar Madasu, M. C. Inácio, 2023, Phytochemistry Letters.

Cycloartane- and Lanostane-Type Triterpenoids from the Resin of Parthenium argentatum AZ-2, a Byproduct of Guayule Rubber Production

D. Dierig, I. Molnár, E. Wijeratne, 2021, ACS omega.

Discovery of small molecule bioactive agents from endophytic fungi of the Sonoran Desert

S. Faeth, A. Arnold, J. Zhan, 2007 .

Argentatin C Analogues with Potential Antinociceptive Activity and Other Triterpenoid Constituents from the Aerial Parts of Parthenium incanum

E. Wijeratne, Aida Calderón-Rivera, S. Perez-Miller, 2023, ACS omega.

The natural product argentatin C attenuates postoperative pain via inhibition of voltage‐gated sodium and T‐type voltage‐gated calcium channels

J. Streicher, E. Wijeratne, G. Zamponi, 2022, British journal of pharmacology.

Withaferin A and Withanolide D Analogues with Dual Heat-Shock-Inducing and Cytotoxic Activities: Semisynthesis and Biological Evaluation.

L. Whitesell, A. Gunatilaka, E. Wijeratne, 2018, Journal of Natural Products.

Geopyxins A-E, ent-kaurane diterpenoids from endolichenic fungal strains Geopyxis aff. majalis and Geopyxis sp. AZ0066: structure-activity relationships of geopyxins and their analogues.

L. Whitesell, J. U’Ren, E. Wijeratne, 2012, Journal of natural products.

Using the heat-shock response to discover anticancer compounds that target protein homeostasis.

S. Lindquist, J. Clardy, S. Kesari, 2011, ACS chemical biology.