A. Brinker

发表

Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry

P. Schultz, L. Brill, S. Ficarro, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Ligand Discrimination by TPR Domains

F. Hartl, C. Herrmann, I. Moarefi, 2002, The Journal of Biological Chemistry.

Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: Systematic variation between sample types and calibration of mass spectrometry data

Gilbert S Omenn, Frank Vitzthum, Shubha Suresh, 2005, Proteomics.

Dual Function of Protein Confinement in Chaperonin-Assisted Protein Folding

D. J. Naylor, F. Hartl, M. Hayer‐Hartl, 2001, Cell.

Identification of Small Molecule and Genetic Modulators of AON-Induced Dystrophin Exon Skipping by High-Throughput Screening

Paul W Anderson, Yingyao Zhou, Buu P. Tu, 2009, PloS one.

Antibody microarrays using resonance light-scattering particles for detection.

B. Geierstanger, A. Brinker, P. Saviranta, 2006, Methods in molecular biology.

Tips A time-resolved fluorescence resonance energy transfer-based assay for DEN 1 peptidase activity

J. Caldwell, I. H. Engels, A. Brinker, 2009 .

Structural Plasticity and Noncovalent Substrate Binding in the GroEL Apical Domain

S. Radford, M. R. Parsons, M. Kaiser, 2002, The Journal of Biological Chemistry.

Crystal structures of human HSP90α-complexed with dihydroxyphenylpyrazoles

J. Caldwell, S. Lesley, A. Kreusch, 2005 .

Identification and Characterization of Small‐Molecule Inducers of Fetal Hemoglobin

P. Schultz, J. Walker, C. Cho, 2011, ChemMedChem.

Cloning of the Xenopus integrin alpha(v) subunit and analysis of its distribution during early development.

T. Joos, A. Brinker, P. Hausen, 1998, The International journal of developmental biology.

In vivo incorporation of unnatural amino acids to probe structure, dynamics, and ligand binding in a large protein by nuclear magnetic resonance spectroscopy.

Susan E. Cellitti, J. Caldwell, P. Schultz, 2008, Journal of the American Chemical Society.

Role of the Myosin Assembly Protein UNC-45 as a Molecular Chaperone for Myosin

F. Hartl, A. Brinker, J. Barral, 2002, Science.

Ligand discrimination by TPR domains : Relevance and selectivity of EEVD-recognition in Hsp 70-Hop-Hsp 90 complexes RUNNING TITLE : PEPTIDE RECOGNITION MOTIFS OF HOP TPR DOMAINS

F. Hartl, C. Herrmann, I. Moarefi, 2002 .

Highly potent inhibitors of human cathepsin L identified by screening combinatorial pentapeptide amide collections.

G. Jung, K. Wiesmüller, D. Stoll, 2000, European journal of biochemistry.

Synthetic small molecules that control stem cell fate

Peter G. Schultz, Eric C. Peters, Nathanael S. Gray, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4

Peter G Schultz, Rudolf Jaenisch, Conrad Kunick, 2009, Proceedings of the National Academy of Sciences.

Measuring the tyrosine kinase activity: a review of biochemical and cellular assay technologies

M. Warmuth, A. Brinker, X. Gu, 2008, Expert opinion on drug discovery.

HTS-Compatible Patient-Derived Cell-Based Assay to Identify Small Molecule Modulators of Aberrant Splicing in Myotonic Dystrophy Type 1

J. Caldwell, I. H. Engels, A. Brinker, 2010, Current chemical genomics.

Structure of TPR Domain–Peptide Complexes Critical Elements in the Assembly of the Hsp70–Hsp90 Multichaperone Machine

Luis Moroder, Gleb Bourenkov, Clemens Scheufler, 2000, Cell.

An intracellular conformational sensor assay for Abl T315I.

J. Caldwell, A. Brinker, Shulin Han, 2009, Analytical biochemistry.

Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells.

R. Jaenisch, P. Schultz, R. Foreman, 2011, Angewandte Chemie.

Small molecule inhibitors of trans-translation have broad-spectrum antibiotic activity

I. H. Engels, A. Chatterjee, K. Keiler, 2013, Proceedings of the National Academy of Sciences.

In silico activity profiling reveals the mechanism of action of antimalarials discovered in a high-throughput screen

Peter G. Schultz, Yingyao Zhou, Elizabeth A. Winzeler, 2008, Proceedings of the National Academy of Sciences.

Time-resolved fluorescence resonance energy transfer and surface plasmon resonance-based assays for retinoid and transthyretin binding to retinol-binding protein 4.

Paul W Anderson, Richard E Trager, J. Caldwell, 2009, Analytical biochemistry.

Identification of inhibitors for putative malaria drug targets among novel antimalarial compounds.

Yu Wang, Gregory J. Crowther, Philip P. Rodenbough, 2011, Molecular and biochemical parasitology.

The protein import motor of mitochondria: a targeted molecular ratchet driving unfolding and translocation

Koji Okamoto, Walter Neupert, Michael Brunner, 2002, The EMBO journal.

A biochemical screen for GroEL/GroES inhibitors.

Steven M. Johnson, P. Schultz, I. H. Engels, 2014, Bioorganic & medicinal chemistry letters.

Pathway Reporter Assays Reveal Small Molecule Mechanisms of Action

Douglas W. Selinger, Frederick J. King, Felipa A. Mapa, 2009 .

Crystal structures of human HSP90alpha-complexed with dihydroxyphenylpyrazoles.

Scott A Lesley, Andreas Kreusch, Yun He, 2005, Bioorganic & medicinal chemistry letters.

Homogeneous High-Throughput Screening Assays for HIV-1 Integrase 3β-Processing and Strand Transfer Activities

J. Caldwell, K. Kuhen, S. Lesley, 2005, Journal of biomolecular screening.

A time-resolved fluorescence resonance energy transfer-based HTS assay and a surface plasmon resonance-based binding assay for heat shock protein 90 inhibitors.

J. Caldwell, H. Klock, A. Brinker, 2004, Analytical biochemistry.

Cellular Ser/Thr-Kinase Assays Using Generic Peptide Substrates

Paul W Anderson, J. Caldwell, A. Orth, 2008, Current chemical genomics.

A time-resolved fluorescence resonance energy transfer-based assay for DEN1 peptidase activity.

Truc Huynh, J. Caldwell, I. H. Engels, 2009, Analytical biochemistry.

Immunoassay and antibody microarray analysis of the HUPO Plasma Proteome Project reference specimens: systematic variation between sample types and calibration of mass spectrometry data.

G. Omenn, G. Michailidis, J. Adkins, 2005, Proteomics.

Evaluating sandwich immunoassays in microarray format in terms of the ambient analyte regime.

Ryan Okon, Petri Saviranta, Masaki Warashina, 2004, Clinical chemistry.