J. Zawistowski

发表

Inhibition of Lapatinib-Induced Kinome Reprogramming in ERBB2-Positive Breast Cancer by Targeting BET Family Bromodomains.

James S. Duncan, Samantha M. Miller, Steven P. Angus, 2015, Cell reports.

GSK2801, a BAZ2/BRD9 Bromodomain Inhibitor, Synergizes with BET Inhibitors to Induce Apoptosis in Triple-Negative Breast Cancer

Steven P. Angus, Darshan Singh, N. Rashid, 2019, Molecular Cancer Research.

Epigenetic Mechanisms Regulating Adaptive Responses to Targeted Kinase Inhibitors in Cancer.

Steven P. Angus, G. Johnson, S. Angus, 2018, Annual review of pharmacology and toxicology.

Proteomic Analysis Defines Kinase Taxonomies Specific for Subtypes of Breast Cancer

T. Oprea, S. Gomez, N. Sciaky, 2017, bioRxiv.

A RhoC Biosensor Reveals Differences in the Activation Kinetics of RhoA and RhoC in Migrating Cells

K. Hahn, G. Danuser, L. Hodgson, 2013, PloS one.

CCM1 and CCM2 protein interactions in cell signaling: implications for cerebral cavernous malformations pathogenesis.

D. Marchuk, B. Ancrile, G. Johnson, 2005, Human molecular genetics.

Loss of p53 sensitizes mice with a mutation in Ccm1 (KRIT1) to development of cerebral vascular malformations.

D. Louis, D. Marchuk, J. Zawistowski, 2004, The American journal of pathology.

Landscaping a chromatin response to MEK inhibition

G. Johnson, J. Zawistowski, D. Goulet, 2017, Cell cycle.

Massively parallel quantification of phenotypic heterogeneity in single-cell drug responses

Z. G. Forbes, J. Hammerbacher, K. Wood, 2020, bioRxiv.

Homogeneous Time-Resolved Fluorescence Resonance Energy Transfer Assay for Measurement of Phox/Bem1p (PB1) Domain Heterodimerization

John E. Scott, G. Johnson, J. Zawistowski, 2008, Journal of biomolecular screening.

SWI/SNF Chromatin-Remodeling Factor Smarcd3/Baf60c Controls Epithelial-Mesenchymal Transition by Inducing Wnt5a Signaling

C. Perou, N. Jordan, Bingying Zhou, 2013, Molecular and Cellular Biology.

Neuronal expression of the Ccm2 gene in a new mouse model of cerebral cavernous malformations

H. Matsunami, D. Marchuk, J. Zawistowski, 2006, Mammalian Genome.

Genetics of cerebral cavernous malformations

D. Marchuk, J. Zawistowski, N. W. Plummer, 2005, Current neurology and neuroscience reports.

Vascular morphogenesis: tales of two syndromes.

D. Marchuk, J. Zawistowski, S. Srinivasan, 2003, Human molecular genetics.

KRIT1 association with the integrin-binding protein ICAP-1: a new direction in the elucidation of cerebral cavernous malformations (CCM1) pathogenesis.

Erica A Golemis, Ilya G Serebriiskii, E. Golemis, 2002, Human molecular genetics.

Molecular Pathways: Adaptive Kinome Reprogramming in Response to Targeted Inhibition of the BRAF–MEK–ERK Pathway in Cancer

Steven P. Angus, L. Graves, G. Johnson, 2014, Clinical Cancer Research.

Dynamic Reprogramming of the Kinome in Response to Targeted MEK Inhibition in Triple-Negative Breast Cancer

Jian Jin, Charles M. Perou, Katherine A. Hoadley, 2012, Cell.

Proteomic analysis defines kinase taxonomies specific for subtypes of breast cancer

Tudor I. Oprea, Steven P. Angus, T. Oprea, 2017, bioRxiv.

MicroRNA 9-3p Targets β1 Integrin To Sensitize Claudin-Low Breast Cancer Cells to MEK Inhibition

J. Parker, G. Johnson, J. Zawistowski, 2013, Molecular and Cellular Biology.

Enhancer Remodeling during Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacologic Targeting of the P-TEFb Complex.

James S. Duncan, Steven P. Angus, C. Perou, 2017, Cancer discovery.

Defining the expressed breast cancer kinome

James S. Duncan, L. Carey, S. Gomez, 2012, Cell Research.

Kinome and Transcriptome Profiling Reveal Broad and Distinct Activities of Erlotinib, Sunitinib, and Sorafenib in the Mouse Heart and Suggest Cardiotoxicity From Combined Signal Transducer and Activator of Transcription and Epidermal Growth Factor Receptor Inhibition

Steven P. Angus, B. Jensen, N. Sciaky, 2017, Journal of the American Heart Association.

The ResolveOME Platform for Comprehensive Analysis of Multi-omic Layers of Single-cell Biology

J. Zawistowski, J. Blackinton, Durga M. Arvapalli, 2022 .

FOXA1 and adaptive response determinants to HER2 targeted therapy in TBCRC 036

Michael L. Gatza, Steven P. Angus, C. Fan, 2021, NPJ breast cancer.

Mutations in a gene encoding a novel protein containing a phosphotyrosine-binding domain cause type 2 cerebral cavernous malformations.

C. Liquori, D. Verlaan, A. Siegel, 2003, American journal of human genetics.

Assessing adaptation of the cancer kinome in response to targeted therapies.

L. Graves, G. Johnson, J. Zawistowski, 2014, Biochemical Society transactions.

Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2

Robert J. Allaway, Steven P. Angus, S. Haggarty, 2018, PloS one.

Discrete Adaptive Responses to MEK Inhibitor in Subpopulations of Triple-Negative Breast Cancer

Darshan Singh, N. Sciaky, G. Johnson, 2020, Molecular Cancer Research.

Enhancer remodeling regulates epigenetic adaptation and resistance to MEK1/2 inhibition in triple-negative breast cancer

G. Johnson, J. Zawistowski, Samantha M. Bevill, 2017, Molecular & cellular oncology.

Eugenol induced changes in the fatty acid content two Lactobacillus species

G. Blank, J. Zawistowski, A. Adejumo, 1991 .

Redesign of the PAK1 autoinhibitory domain for enhanced stability and affinity in biosensor applications.

B. Kuhlman, Yi I. Wu, K. Hahn, 2011, Journal of molecular biology.

Unifying genomics and transcriptomics in single cells with ResolveOME amplification chemistry to illuminate oncogenic and drug resistance mechanisms

V. Weigman, Jay A. West, Isai Salas-González, 2022 .

Automated line scan analysis to quantify biosensor activity at the cell edge.

R J Allen, D Tsygankov, J S Zawistowski, 2014, Methods.

Patterning pallet arrays for cell selection based on high-resolution measurements of fluorescent biosensors.

K. Hahn, N. Allbritton, J. Zawistowski, 2011, Analytica chimica acta.

MAP3K4 Controls the Chromatin Modifier HDAC6 during Trophoblast Stem Cell Epithelial-to-Mesenchymal Transition.

S. Gomez, R. Homayouni, G. Johnson, 2017, Cell reports.

Unifying comprehensive genomics and transcriptomics in individual cells to illuminate oncogenic and drug resistance mechanisms

V. Weigman, Isai Salas-González, J. Zawistowski, 2023, bioRxiv.

Enhancer Remodeling During Adaptive Bypass to MEK Inhibition Is Attenuated by Pharmacological Targeting of the PTEFb Complex

C. Perou, Darshan Singh, Xiaping He, 2017 .