K. Leroy

发表

Developmental expression and localization of glycogen synthase kinase-3β in rat brain

J. Brion, K. Leroy, 1999, Journal of Chemical Neuroanatomy.

Bimodal modulation of tau protein phosphorylation and conformation by extracellular Zn2+ in human-tau transfected cells.

J. Brion, K. Leroy, R. van Heurck, 2009, Biochimica et biophysica acta.

Rapamycin ester analog CCI-779/Temsirolimus alleviates tau pathology and improves motor deficit in mutant tau transgenic mice.

L. Buée, K. Ando, Céline Héraud, 2015, Journal of Alzheimer's disease : JAD.

Deletion of Irs2 reduces amyloid deposition and rescues behavioural deficits in APP transgenic mice

S. Lovestone, D. Withers, K. Giese, 2009, Biochemical and biophysical research communications.

Lithium Chloride Increases the Production of Amyloid-β Peptide Independently from Its Inhibition of Glycogen Synthase Kinase 3*

P. Courtoy, J. Brion, K. Leroy, 2005, Journal of Biological Chemistry.

Increased tau phosphorylation but absence of formation of neurofibrillary tangles in mice double transgenic for human tau and Alzheimer mutant (M146L) presenilin-1

V. Blanchard, K. Leroy, N. Touchet, 2002, Neuroscience Letters.

Amyloid precursor protein reduction enhances the formation of neurofibrillary tangles in a mutant tau transgenic mouse model

L. Buée, J. Brion, K. Leroy, 2017, Neurobiology of Aging.

Motor deficit in a tauopathy model is induced by disturbances of axonal transport leading to dying-back degeneration and denervation of neuromuscular junctions.

L. Poncelet, J. Brion, K. Leroy, 2015, The American journal of pathology.

Vaccination with Sarkosyl insoluble PHF-tau decrease neurofibrillary tangles formation in aged tau transgenic mouse model: a pilot study.

C. Duyckaerts, M. Potier, K. Ando, 2014, Journal of Alzheimer's disease : JAD.

The function of the microtubule‐associated protein tau is variably modulated by graded changes in glycogen synthase kinase‐3β activity

S. Lovestone, K. Leroy, B. Anderton, 2000, FEBS letters.

Intravenous Injection of PHF-Tau Proteins From Alzheimer Brain Exacerbates Neuroinflammation, Amyloid Beta, and Tau Pathologies in 5XFAD Transgenic Mice

L. Poncelet, K. Ando, J. Brion, 2020, Frontiers in Molecular Neuroscience.

of Tau Proteins Rescues Neuronal Cell Death and Decreases Amyloidogenic Processing of APP in APP/PS1 Mice." and Decreases of APP in

V. Laporte, K. Ando, Céline Héraud, 2018 .

PHF-tau propagation in the presence of Amyloid ß pathology

C. Duyckaerts, K. Ando, J. Brion, 2016 .

Analysis of Peripapillary Intrachoroidal Cavitation and Myopic Peripapillary Distortions in Polar Regions by Optical Coherence Tomography

K. Leroy, A. Ehongo, A. Dugauquier, 2022, Clinical ophthalmology.

Developmental expression and localization of glycogen synthase kinase-3beta in rat brain.

K. Leroy, J. Brion, 1999, Journal of chemical neuroanatomy.

Phrenic motor neuron degeneration compromises phrenic axonal circuitry and diaphragm activity in a unilateral cervical contusion model of spinal cord injury

J. Brion, K. Leroy, C. Nicaise, 2012, Experimental Neurology.

A 4R tauopathy develops without amyloid deposits in aged cat brains

E. Gilissen, L. Poncelet, K. Ando, 2019, Neurobiology of Aging.

Cell surface targeting of VPAC1 receptors: evidence for implication of a quality control system and the proteasome.

J. Brion, P. Robberecht, K. Leroy, 2008, Biochimica et biophysica acta.

Mint2/X11‐like colocalizes with the Alzheimer's disease amyloid precursor protein and is associated with neuritic plaques in Alzheimer's disease

Christopher C. J. Miller, D. McLoughlin, J. Brion, 1999, The European journal of neuroscience.

Neurofibrillary tangles and tau phosphorylation.

S. Lovestone, J. Brion, K. Leroy, 2001, Biochemical Society symposium.

Increased level of active GSK‐3β in Alzheimer’s disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration

K. Leroy, Z. Yılmaz, J. Brion, 2007, Neuropathology and applied neurobiology.

A neuronal aging pattern unique to humans and common chimpanzees

P. Hof, C. Sherwood, C. Bouras, 2014, Brain Structure and Function.

A neuronal aging pattern unique to humans and common chimpanzees

P. Hof, C. Sherwood, C. Bouras, 2014, Brain Structure and Function.

Alzheimer's Disease: Tau Pathology and Dysfunction of Endocytosis

C. Erneux, M. Potier, K. Ando, 2021, Frontiers in Molecular Neuroscience.

Amyloid-β pathology enhances pathological fibrillary tau seeding induced by Alzheimer PHF in vivo

K. Ando, J. Brion, K. Leroy, 2019, Acta Neuropathologica.

Hallmarks of Alzheimer’s Disease in Stem-Cell-Derived Human Neurons Transplanted into Mouse Brain

Amaia M. Arranz, J. Hardy, B. Strooper, 2017, Neuron.

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway

G. Breen, R. Dobson, S. Lovestone, 2012, Molecular Psychiatry.

In vivo stimulation of macroautophagy: Effect on tau accumulation in neurons and on tau pathology in mutant tau mice

J. Brion, K. Leroy, C. Frédérick, 2011, Alzheimer's & Dementia.

Unraveling Human AQP5-PIP Molecular Interaction and Effect on AQP5 Salivary Glands Localization in SS Patients

K. Schey, Zhen Wang, C. Delporte, 2021, Cells.

P1–062: Alzheimer's disease–like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

L. Buée, J. Brion, K. Leroy, 2006, The American journal of pathology.

Epigenetic control of aquaporin 1 expression by the amyloid precursor protein

S. Hébert, B. de Strooper, O. Devuyst, 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology.

Christophe Erneux, Stéphane Schurmans, Kunie Ando, 2014, Brain : a journal of neurology.

Tau Pathology and Adult Hippocampal Neurogenesis: What Tau Mouse Models Tell us?

K. Ando, J. Brion, K. Leroy, 2021, Frontiers in Neurology.

Expression of tau mRNA and soluble tau isoforms in affected and non‐affected brain areas in Alzheimer's disease

J. Brion, K. Leroy, A. Boutajangout, 2004, FEBS letters.

Dysregulation of Phosphoinositide 5-Phosphatases and Phosphoinositides in Alzheimer's Disease

C. Erneux, K. Ando, J. Brion, 2021, Frontiers in Neuroscience.

The lipid phosphatase Synaptojanin 1 undergoes a significant alteration in expression and solubility and is associated with brain lesions in Alzheimer’s disease

C. Duyckaerts, V. Deramecourt, F. Chapon, 2020, Acta Neuropathologica Communications.

Lack of tau proteins rescues neuronal cell death and decreases amyloidogenic processing of APP in APP/PS1 mice.

V. Laporte, K. Ando, Céline Héraud, 2012, The American journal of pathology.

Lithium treatment arrests the development of neurofibrillary tangles in mutant tau transgenic mice with advanced neurofibrillary pathology.

L. Buée, J. Boeynaems, K. Ando, 2010, Journal of Alzheimer's disease : JAD.

Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation

S. Lovestone, R. Dayanandan, S. Lovestone, 1999, FEBS letters.

PICALM and Alzheimer’s Disease: An Update and Perspectives

K. Ando, J. Brion, K. Leroy, 2022, Cells.

Sex-regulated gene dosage effect of PPARα on synaptic plasticity

I. Dewachter, B. Staels, J. Brion, 2019, Life Science Alliance.

Deletion of murine tau gene increases tau aggregation in a human mutant tau transgenic mouse model.

K. Ando, Céline Héraud, Anna Kabova, 2010, Biochemical Society transactions.

Increased misfolding and truncation of tau in APP/PS1/tau transgenic mice compared to mutant tau mice

V. Laporte, K. Ando, Céline Héraud, 2014, Neurobiology of Disease.

Accelerated human mutant tau aggregation by knocking out murine tau in a transgenic mouse model.

K. Ando, Céline Héraud, J. Brion, 2011, The American journal of pathology.

Modulation of tau pathology in tau transgenic models.

K. Ando, Céline Héraud, J. Brion, 2010, Biochemical Society transactions.

Regulation of PPARα by APP in Alzheimer disease affects the pharmacological modulation of synaptic activity

C. Duyckaerts, T. Leroy, B. Staels, 2021, JCI insight.

Tyrosine 394 Is Phosphorylated in Alzheimer's Paired Helical Filament Tau and in Fetal Tau with c-Abl as the Candidate Tyrosine Kinase

Wendy Noble, Christof Lenz, Kit-Yi Leung, 2005, The Journal of Neuroscience.

High-Molecular-Weight Paired Helical Filaments from Alzheimer Brain Induces Seeding of Wild-Type Mouse Tau into an Argyrophilic 4R Tau Pathology in Vivo.

L. Buée, K. Ando, J. Brion, 2016, The American journal of pathology.

Early axonopathy preceding neurofibrillary tangles in mutant tau transgenic mice.

L. Buée, E. Gilissen, J. Brion, 2007, The American journal of pathology.

The active form of glycogen synthase kinase-3β is associated with granulovacuolar degeneration in neurons in Alzheimer's disease

J. Woodgett, J. Brion, K. Leroy, 2002, Acta Neuropathologica.

Sites of phosphorylation in tau and factors affecting their regulation.

S. Lovestone, W. Blackstock, D. Hanger, 2000, Biochemical Society symposium.

de novo MAPT mutation G335A causes severe brain atrophy, 3R and 4R PHF-tau pathology and early onset frontotemporal dementia

A. Durr, M. Sarazin, I. Le Ber, 2020, Acta Neuropathologica Communications.

Increase of adenomatous polyposis coli immunoreactivity is a marker of reactive astrocytes in Alzheimer's disease and in other pathological conditions

C. Duyckaerts, K. Leroy, B. Anderton, 2001, Acta Neuropathologica.

Stereotaxic injection of fibrillar PHF from Alzheimer brain induces propagation of argyrophilic grains constituted of murine tau in mouse brains

L. Buée, K. Ando, J. Brion, 2016 .

Genetic ablation of tau in postnatal neurons rescues decreased adult hippocampal neurogenesis in a tauopathy model

L. Buée, K. Ando, J. Brion, 2019, Neurobiology of Disease.

Mutant presenilin 1 proteins induce cell death and reduce tau-dependent processes outgrowth

S. Lovestone, K. Leroy, J. Octave, 2003, Neuroscience Letters.

Picalm reduction exacerbates tau pathology in a murine tauopathy model

L. Buée, C. Duyckaerts, K. Sleegers, 2020, Acta Neuropathologica.

Alzheimer PHF-tau aggregates do not spread tau pathology to the brain via the Retino-tectal projection after intraocular injection in male mouse models

L. Buée, K. Ando, J. Brion, 2022, Neurobiology of Disease.

Degeneration of phrenic motor neurons induces long-term diaphragm deficits following mid-cervical spinal contusion in mice.

J. Brion, K. Leroy, R. Pochet, 2012, Journal of neurotrauma.

The lipid phosphatase Synaptojanin 1 undergoes a significant alteration in expression and solubility and is associated with brain lesions in Alzheimer’s disease

C. Duyckaerts, V. Deramecourt, F. Chapon, 2020, Acta Neuropathologica Communications.

Sex-regulated gene dosage effect of PPARα on synaptic plasticity

I. Dewachter, B. Staels, J. Brion, 2019, Life Science Alliance.

P1-062 Alzheimer’s disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits

L. Buée, J. Brion, K. Leroy, 2006, Alzheimer's & Dementia.

Inositol trisphosphate 3-kinase B is increased in human Alzheimer brain and exacerbates mouse Alzheimer pathology.

C. Duyckaerts, S. Schurmans, C. Erneux, 2014, Brain : a journal of neurology.

Alteration of gene expression and protein solubility of the PI 5-phosphatase SHIP2 are correlated with Alzheimer’s disease pathology progression

K. Sleegers, K. Ando, J. Brion, 2024, Acta neuropathologica.