J. Wieling

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LC-MS-MS experiences with internal standards

J. Wieling, 2002 .

'High throughput' solid-phase extraction technology and turbo ionspray LC-MS-MS applied to the determination of haloperidol in human plasma.

J. Wieling, J. Jonkman, J. Hempenius, 1999, Journal of pharmaceutical and biomedical analysis.

Chemometrics in bioanalytical sample preparation. A fractionated combined mixture and factorial design for the modelling of the recovery of five tricyclic amines from plasma after liquid-liquid extraction prior to high-performance liquid chromatography.

C. Duineveld, J. Wieling, P. Coenegracht, 1993, Journal of chromatography.

High temperature liquid chromatography hyphenated with ESI-MS and ICP-MS detection for the structural characterization and quantification of halogen containing drug metabolites.

M. Honing, M. Giera, J. Kool, 2011, Analytica chimica acta.

LC‐MS Bioanalysis of Unbound Drugs in Plasma and Serum

J. Wieling, T. Boer, 2013 .

CYP2D6 and CYP2C19 activity in a large population of Dutch healthy volunteers: indications for oral contraceptive-related gender differences

R. A. Zeeuw, B. Wilffert, J. Wieling, 1999, European Journal of Clinical Pharmacology.

White Pa P er SP ecial Focu S iSS ue: Bioanaly S i S o F B iomarker S

Rafiq Islam, R. Lelacheur, S. Reuschel, 2012 .

Quantification of asenapine and three metabolites in human plasma using liquid chromatography-tandem mass spectrometry with automated solid-phase extraction: application to a phase I clinical trial with asenapine in healthy male subjects.

Erik A. Meulman, T. de Boer, J. Wieling, 2012, Biomedical chromatography : BMC.

Inductively coupled plasma-MS in drug development: bioanalytical aspects and applications.

J. Wieling, H. Meijering, Fred van Heuveln, 2012, Bioanalysis.

Validation of a method for the determination of thiocyanate in human plasma by UV/VIS spectrophotometry and application to a Phase I clinical trial of GDC-0425

F. V. Heuveln, J. Wieling, C. Hop, 2015 .

High-throughput solid-phase extraction for the determination of cimetidine in human plasma.

F. Maris, J. Wieling, J. Jonkman, 1998, Journal of chromatography. B, Biomedical sciences and applications.

SELECTION OF ROBUST COMBINATIONS OF EXTRACTION LIQUID COMPOSITION AND INTERNAL STANDARD - MONTE-CARLO SIMULATION OF IMPROVEMENT OF ASSAY-METHODS WITH LIQUID-LIQUID-EXTRACTION PRIOR TO HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

J. Wieling, P. Coenegracht, J. Jonkman, 1992 .

Development and validation of automated SPE-HPLC-MS/MS methods for the quantification of asenapine, a new antipsychotic agent, and its two major metabolites in human urine.

Erik A. Meulman, T. de Boer, J. Wieling, 2012, Biomedical chromatography : BMC.

Current Understanding of Bioanalytical Assay Reproducibility: Incurred Sample Reanalysis, Incurred Sample Stability, and Incurred Sample Accuracy

Theo de Boer, Manish S. Yadav, Pranav S. Shrivastav, 2013 .

Mephenytoin as a probe for CYP2C19 phenotyping:effect of sample storage, intra-individual reproducibility and occurrence of adverse events.

D. Touw, J. Wieling, J. Jonkman, 2001, British journal of clinical pharmacology.

Pharmacokinetics of [14C]-labelled losigamone and enantiomers after oral administration to healthy subjects

J. Wieling, J. Jonkman, P. Peeters, 2010, European Journal of Drug Metabolism and Pharmacokinetics.

Effect of low‐dose ritonavir (100 mg twice daily) on the activity of cytochrome P450 2D6 in healthy volunteers

D. Touw, J. Wieling, R. Aarnoutse, 2005, Clinical pharmacology and therapeutics.

Recommendations on biomarker bioanalytical method validation by GCC.

Roger Hayes, Fabio Garofolo, John Allinson, 2012, Bioanalysis.

AS A PROBE FOR THE CYP 2 C 19 ACTIVITY : A CRITICAL EVALUATION OF ITS APPLICABILITY IN EPIDEMIOLOGY AND CLINICAL PHARMACOLOGY

R. A. Zeeuw, B. Wilffert, D. Touw, 2018 .

2.1 MEPHENYTOIN AS A PROBE FOR THE CYP2C19 ACTIVITY: A CRITICAL EVALUATION OF ITS APPLICABILITY IN EPIDEMIOLOGY AND CLINICAL PHARMACOLOGY

R. A. Zeeuw, B. Wilffert, D. Touw, 2001 .

Incurred sample accuracy assessment: design of experiments based on standard addition.

Jaap Wieling, Theo de Boer, T. de Boer, 2011, Bioanalysis.

PART III APPLICATION IN EPIDEMIOLOGY 3 . 1 CYP 2 D 6 AND CYP 2 C 19 ACTIVITY IN A LARGE POPULATION OF DUTCH HEALTHY VOLUNTEERS : INDICATIONS FOR ORAL CONTRACEPTIVE-RELATED GENDER DIFFERENCES

R. A. Zeeuw, B. Wilffert, J. Wieling, 2018 .

Clinical and Bioanalytical Evaluation of Dried Blood spot Sampling for Genotyping and Phenotyping of Cytochrome p450 Enzymes in Healthy Volunteers

J. Wieling, T. Boer, J. Wemer, 2014 .

Application of dried blood spot sampling combined with LC-MS/MS for genotyping and phenotyping of CYP450 enzymes in healthy volunteers.

Erik A. Meulman, T. de Boer, J. Wieling, 2011, Biomedical chromatography : BMC.

IS addition in bioanalysis of DBS: results from the EBF DBS-microsampling consortium.

S. Wood, O. Heudi, P. Timmerman, 2013, Bioanalysis.

Robust, fit-for-purpose method transfer: why we should apply equivalence testing.

J. Wieling, 2015, Bioanalysis.

Development of a laboratory robotic system for automated bioanalytical methods--I. The determination of theophylline in human plasma: a comparison between the robotized and manual method.

O. D. de Noord, J. Wieling, P. Coenegracht, 1990, Journal of pharmaceutical and biomedical analysis.

Rational experimental design for bioanalytical methods validation. Illustration using an assay method for total captopril in plasma.

J. Wieling, J Hempenius, J Wieling, 1996, Journal of chromatography. A.

Alternative methods for internal quality control in research laboratories for environmental analysis: a programme for the performance evaluation of equipment, methods and staff

J. Wieling, H. A. Bakkeren, R. J. Peters, 1994 .

Evaluation of analytical and clinical performance of a dual-probe phenotyping method for CYP2D6 polymorphism and CYP3A4 activity screening.

J. Wieling, J. Jonkman, J. Jonkman, 2000, Therapeutic drug monitoring.

Technical aspects of inductively coupled plasma bioanalysis techniques.

J. Wieling, J. Sailstad, Phillip Wang, 2013, Bioanalysis.

2015 White Paper on recent issues in bioanalysis: focus on new technologies and biomarkers (Part 2 - hybrid LBA/LCMS and input from regulatory agencies).

Surinder Kaur, Jian Wang, Fabio Garofolo, 2015, Bioanalysis.

Chapter 7 Robustness of liquid-liquid extraction of drugs from biological samples

J. Wieling, 1996 .

Formation of a Global Contract Research Organization Council for Bioanalysis.

Xinping Fang, Fabio Garofolo, Chad Briscoe, 2010, Bioanalysis.

Technical aspects of inductively coupled plasma bioanalysis techniques.

J. Wieling, J. Sailstad, Phillip Wang, 2013, Bioanalysis.

Conference report: the 3rd Global CRO Council for Bioanalysis at the International Reid Bioanalytical Forum.

Fabio Garofolo, Rachel Green, Jaap Wieling, 2011, Bioanalysis.

An Empirical Study on the Impact of Bioanalytical Method Variability on Estimation of PK Parameters

J. Wieling, C. Tump, 2004 .