J. Abisambra

发表

Janna H. Neltner, K. Jellinger, J. Schneider, 2014, Acta Neuropathologica.

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

F. Tovar-Moll, O. Arancio, D. Wilcock, 2018, Nature Medicine.

Brain injury in the context of tauopathies.

S. Scheff, J. Abisambra, 2014, Journal of Alzheimer's disease : JAD.

Manganese-Enhanced Magnetic Resonance Imaging: Overview and Central Nervous System Applications With a Focus on Neurodegeneration

J. Abisambra, Ryan A. Cloyd, Shon A Koren, 2018, Front. Aging Neurosci..

Male-specific epistasis between WWC1 and TLN2 genes is associated with Alzheimer's disease

J. Haines, M. Pericak-Vance, G. Schellenberg, 2018, Neurobiology of Aging.

Chronic PERK induction promotes Alzheimer-like neuropathology in Down syndrome: Insights for therapeutic intervention

D. Butterfield, F. Locatelli, E. Barone, 2020, Progress in Neurobiology.

The Hsp90 Cochaperone, FKBP51, Increases Tau Stability and Polymerizes Microtubules

J. Buchner, S. Borysov, M. B. Cox, 2010, The Journal of Neuroscience.

TheHsp90Cochaperone,FKBP51,IncreasesTauStability andPolymerizesMicrotubules

J. Abisambra, U. Jinwal, Jeffrey R. Jones, 2010 .

Cerebral Microvascular Accumulation of Tau Oligomers in Alzheimer’s Disease and Related Tauopathies

U. Sengupta, J. Troncoso, P. Nelson, 2017, Aging and disease.

Non-invasive detection of adeno-associated viral gene transfer using a genetically encoded CEST-MRI reporter gene in the murine heart

E. Gao, A. Gilad, M. Vandsburger, 2018, Scientific Reports.

Facilitating Akt Clearance via Manipulation of Hsp70 Activity and Levels*

J. Cheng, J. Gestwicki, Jian-ping Guo, 2009, The Journal of Biological Chemistry.

Cdc37/Hsp90 Protein Complex Disruption Triggers an Autophagic Clearance Cascade for TDP-43 Protein

J. Gestwicki, Juan Zhang, J. Abisambra, 2012, The Journal of Biological Chemistry.

RNA binding proteins co-localize with small tau inclusions in tauopathy

Hu Li, Cheng Zhang, J. Leszyk, 2018, Acta neuropathologica communications.

Brain mapping and spatial protein profiling reveal functional connectivity deficits and molecular changes following repetitive mild traumatic brain injury in wild-type mice

Matteo M. Grudny, M. Febo, J. Koren, 2022, bioRxiv.

Glucose-regulated Protein 94 Triage of Mutant Myocilin through Endoplasmic Reticulum-associated Degradation Subverts a More Efficient Autophagic Clearance Mechanism*

B. Blagg, M. Cockman, J. Koren, 2012, The Journal of Biological Chemistry.

Early and Selective Activation and Subsequent Alterations to the Unfolded Protein Response in Down Syndrome Mouse Models.

E. Barone, J. Abisambra, A. Tramutola, 2018, Journal of Alzheimer's disease : JAD.

Q134R: Small chemical compound with NFAT inhibitory properties improves behavioral performance and synapse function in mouse models of amyloid pathology

L. Puskás, C. Norris, J. Abisambra, 2021, Aging cell.

Identification of Novel Tau Interactions with Endoplasmic Reticulum Proteins in Alzheimer's Disease Brain.

J. Gensel, P. Nelson, Haining Zhu, 2015, Journal of Alzheimer's disease : JAD.

Interaction of tau with the RNA-Binding Protein TIA1 Regulates tau Pathophysiology and Toxicity.

Hu Li, L. Petrucelli, P. Ivanov, 2016, Cell reports.

Allosteric Heat Shock Protein 70 Inhibitors Rapidly Rescue Synaptic Plasticity Deficits by Reducing Aberrant Tau

J. Rogers, E. Weeber, J. Brodsky, 2013, Biological Psychiatry.

Tau-mediated dysregulation of RNA: Evidence for a common molecular mechanism of toxicity in frontotemporal dementia and other tauopathies

J. Abisambra, Shon A. Koren, Sara M. Galvis-Escobar, 2020, Neurobiology of Disease.

ApoER2 Function in the Establishment and Maintenance of Retinal Synaptic Connectivity

E. Weeber, C. B. Rickman, D. Birch, 2011, The Journal of Neuroscience.

Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy.

Hu Li, A. Emili, L. Petrucelli, 2021, Molecular cell.

Non-invasive detection of adeno-associated viral gene transfer using a genetically encoded CEST-MRI reporter gene in the murine heart

E. Gao, A. Gilad, M. Vandsburger, 2018, Scientific Reports.

Exploiting the Diversity of the Heat-Shock Protein Family for Primary and Secondary Tauopathy Therapeutics

J. Koren, J. Abisambra, U. Jinwal, 2011, Current neuropharmacology.

Hsp70 ATPase Modulators as Therapeutics for Alzheimer's and other Neurodegenerative Diseases.

J. Koren, J. Abisambra, U. Jinwal, 2010, Molecular and cellular pharmacology.

Tau accumulation activates the unfolded protein response by impairing endoplasmic reticulum-associated degradation

J. Abisambra, U. Jinwal, C. Dickey, 2013, Alzheimer's & Dementia.

The Hsp90 Kinase Co-chaperone Cdc37 Regulates Tau Stability and Phosphorylation Dynamics*

E. Weeber, Lisa Y. Lawson, J. Koren, 2011, The Journal of Biological Chemistry.

MW151 Inhibited IL-1β Levels after Traumatic Brain Injury with No Effect on Microglia Physiological Responses

Bin Xing, C. Borlongan, L. V. Van Eldik, 2016, PloS one.

Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis

H. Levine, Haining Zhu, J. Abisambra, 2016, The Journal of Neuroscience.

The impact of PERK on post-traumatic tauopathy in Alzheimer ’ s disease

J. Abisambra, 2017 .

Proteomic Techniques to Examine Neuronal Translational Dynamics

J. Abisambra, Simon D’Alton, Matthew Hamm, 2019, International journal of molecular sciences.

Imbalance of Hsp70 family variants fosters tau accumulation

V. Uversky, E. Mandelkow, J. Gestwicki, 2013, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Hsc70 Rapidly Engages Tau after Microtubule Destabilization*

J. Gestwicki, S. Borysov, Lisa Y. Lawson, 2010, The Journal of Biological Chemistry.

LDLR Expression and Localization Are Altered in Mouse and Human Cell Culture Models of Alzheimer's Disease

J. Padmanabhan, H. Potter, J. Abisambra, 2010, PloS one.

Paired associates learning is disrupted after unilateral parietal lobe controlled cortical impact in rats: A trial-by-trial behavioral analysis

S. Burke, Abbi R. Hernandez, Quinten P. Federico, 2022, Behavioural Brain Research.

Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer’s models

F. Tovar-Moll, O. Arancio, D. Wilcock, 2019, Nature Medicine.

PERK-opathies: An Endoplasmic Reticulum Stress Mechanism Underlying Neurodegeneration.

J. Abisambra, Shelby Meier, Michelle C. Bell, 2016, Current Alzheimer research.

Phosphorylation Dynamics Regulate Hsp27-Mediated Rescue of Neuronal Plasticity Deficits in Tau Transgenic Mice

J. Rogers, E. Weeber, D. Wilcock, 2010, The Journal of Neuroscience.

PhosphorylationDynamicsRegulateHsp27-Mediated RescueofNeuronalPlasticityDeficitsinTauTransgenic Mice

J. Abisambra, U. Jinwal, Amelia G. Johnson, 2010 .

Broad Kinase Inhibition Mitigates Early Neuronal Dysfunction in Tauopathy

N. Seyfried, D. Duong, D. Powell, 2021, International Journal of Molecular Sciences.

Big tau aggregation disrupts microtubule tyrosination and causes myocardial diastolic dysfunction: from discovery to therapy.

R. Kayed, O. Albayram, J. Abisambra, 2023, European heart journal.

Association between single moderate to severe traumatic brain injury and long-term tauopathy in humans and preclinical animal models: a systematic narrative review of the literature

S. DeKosky, J. Abisambra, Benjamin Albert Chapin, 2022, Acta neuropathologica communications.

The effects of mild closed head injuries on tauopathy and cognitive deficits in rodents: Primary results in wild type and rTg4510 mice, and a systematic review

D. Powell, L. V. Van Eldik, M. Vandsburger, 2020, Experimental Neurology.

The diarylheptanoid (+)-aR,11S-myricanol and two flavones from bayberry (Myrica cerifera) destabilize the microtubule-associated protein tau.

John Koren, E. Weeber, C. Eckman, 2011, Journal of natural products.

Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer’s disease

P. Fraser, P. Rosa-Neto, P. Caramelli, 2021, Translational Psychiatry.

Tau drives translational selectivity by interacting with ribosomal proteins

E. Blalock, Haining Zhu, J. Abisambra, 2019, Acta Neuropathologica.

Phenothiazine-mediated rescue of cognition in tau transgenic mice requires neuroprotection and reduced soluble tau burden

Jason E Gestwicki, John Koren, Laura J Blair, 2010, Molecular Neurodegeneration.

Broad kinase inhibition mitigates early neuronal dysfunction and cognitive deficits in tauopathy

N. Seyfried, D. Duong, D. Powell, 2020, bioRxiv.

Fixed Time-Point Analysis Reveals Repetitive Mild Traumatic Brain Injury Effects on Resting State Functional Magnetic Resonance Imaging Connectivity and Neuro-Spatial Protein Profiles

Matteo M. Grudny, M. Febo, J. Abisambra, 2023, Journal of neurotrauma.

TauAccumulationActivatestheUnfoldedProteinResponse byImpairingEndoplasmicReticulum-Associated Degradation

J. Abisambra, 2013 .

DnaJA1 antagonizes constitutive Hsp70-mediated stabilization of tau.

M. Cockman, J. Abisambra, Ying Jin, 2012, Journal of molecular biology.

Identification of changes in neuronal function as a consequence of aging and tauopathic neurodegeneration using a novel and sensitive magnetic resonance imaging approach

D. Powell, M. Vandsburger, J. Abisambra, 2017, Neurobiology of Aging.