J. Schnitzer

发表

Label-free, normalized quantification of complex mass spectrometry data for proteomics analysis

J. Koziol, N. Griffin, Jingyi Yu, 2009, Nature Biotechnology.

Iodine-125 radiolabeling of silver nanoparticles for in vivo SPECT imaging

J. Schnitzer, A. Chrastina, 2010, International journal of nanomedicine.

Albumin interacts specifically with a 60-kDa microvascular endothelial glycoprotein.

G. Palade, J. Schnitzer, W. Carley, 1988, Proceedings of the National Academy of Sciences of the United States of America.

Role of caveolae and lipid rafts in cancer: workshop summary and future needs.

Richard G. W. Anderson, S. Mohla, J. Schnitzer, 2003, Cancer research.

Caveolae: mining little caves for new cancer targets

Jan E. Schnitzer, J. Schnitzer, L. A. Carver, 2003, Nature Reviews Cancer.

Tumor cell growth inhibition by caveolin re-expression in human breast cancer cells

Jan E Schnitzer, Sam W. Lee, C. Reimer, 1998, Oncogene.

I. Embryonal vasculature formation recapitulated in transgenic mammary tumor spheroids implanted pseudo-orthotopicly into mouse dorsal skin fold: the organoblasts concept

P. Oh, J. Schnitzer, H. Witkiewicz, 2013, F1000Research.

Ubiquitous yet Distinct Expression of Podocalyxin on Vascular Surfaces in Normal and Tumor Tissues in the Rat

P. Oh, Yan Li, J. Schnitzer, 2009, Journal of Vascular Research.

Chapter 8. Proteomic mapping of the vascular endothelium in vivo for vascular targeting.

N. Griffin, J. Schnitzer, 2008, Methods in enzymology.

Screening phage display libraries for organ-specific vascular immunotargeting in vivo.

Jan E Schnitzer, P. Oh, J. Schnitzer, 2006, Proceedings of the National Academy of Sciences of the United States of America.

Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy

Yan Li, Eberhard Durr, Jan E. Schnitzer, 2004, Nature.

Direct proteomic mapping of the lung microvascular endothelial cell surface in vivo and in cell culture

Eberhard Durr, John R Yates, Jan E Schnitzer, 2004, Nature Biotechnology.

Vascular targeting as a strategy for cancer therapy.

J. Schnitzer, 1998, The New England journal of medicine.

Erratum: Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung

Yan Li, Jan E Schnitzer, P. Oh, 2007, Nature Biotechnology.

gp60 is an albumin-binding glycoprotein expressed by continuous endothelium involved in albumin transcytosis.

J. Schnitzer, 1992, The American journal of physiology.

Assessing the barriers to image-guided drug delivery.

Yong-Eun Koo Lee, K. Hynynen, D. Sept, 2014, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules

P. Oh, J. Schnitzer, J E Schnitzer, 1994, The Journal of cell biology.

Update on the cellular and molecular basis of capillary permeability.

J. Schnitzer, 1993, Trends in cardiovascular medicine.

Different ODE models of tumor growth can deliver similar results

J. Koziol, T. Falls, J. Schnitzer, 2020, BMC Cancer.

Fiber matrix model reanalysis: matrix exclusion limits define effective pore radius describing capillary and glomerular permselectivity.

J. Schnitzer, 1992, Microvascular research.

ERs associate with and regulate the production of caveolin: implications for signaling and cellular actions.

E. Levin, M. Razandi, A. Pedram, 2002, Molecular endocrinology.

Lessons from the Past: Methodological Issues Arising from Comparison of the Disease Burden of the Influenza A (H1N1) Pandemic 2009–10 and Seasonal Influenza 2010–2019 in the United States

J. Koziol, J. Schnitzer, 2021, Journal of infectious diseases and epidemiology.

Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor.

B. Jacobson, A. Dvorak, P. Oh, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Endothelin Induces Rapid, Dynamin-mediated Budding of Endothelial Caveolae Rich in ET-B*

P. Oh, J. Schnitzer, H. Witkiewicz, 2012, The Journal of Biological Chemistry.

Transient Mechanoactivation of Neutral Sphingomyelinase in Caveolae to Generate Ceramide*

P. Oh, J. Schnitzer, Jun Liu, 2003, The Journal of Biological Chemistry.

Déjà vu all over again: racial, ethnic and age disparities in mortality from influenza 1918–19 and COVID-19 in the United States

J. Koziol, J. Schnitzer, 2022, Heliyon.

Tumor Targeting, Trifunctional Dendritic Wedge

B. Olenyuk, P. Oh, J. Schnitzer, 2014, Bioconjugate chemistry.

Isolation and Subfractionation of Plasma Membranes to Purify Caveolae Separately from Lipid Rafts

P. Oh, J. Schnitzer, L. A. Carver, 2006 .

Immunoisolation of Caveolae with High Affinity Antibody Binding to the Oligomeric Caveolin Cage

P. Oh, J. Schnitzer, 1999, The Journal of Biological Chemistry.

Analysis of lipids in caveolae.

J. Schnitzer, J. Liu, 1999, Methods in molecular biology.

Flotillin and Epidermal Surface Antigen Define a New Family of Caveolae-associated Integral Membrane Proteins*

H. Lodish, M. Lisanti, P. Scherer, 1997, The Journal of Biological Chemistry.

Genomics and proteomics of lung disease: conference summary.

John Quackenbush, Naftali Kaminski, Scott T Weiss, 2007, American journal of physiology. Lung cellular and molecular physiology.

Co-implanting orthotopic tissue creates stroma microenvironment enhancing growth and angiogenesis of multiple tumors.

P. Oh, J. Schnitzer, P. Borgstrom, 2013, F1000Research.

Preferential interaction of albumin-binding proteins, gp30 and gp18, with conformationally modified albumins. Presence in many cells and tissues with a possible role in catabolism.

R. Horvat, J. Schnitzer, J. Bravo, 1992, The Journal of biological chemistry.

High affinity binding, endocytosis, and degradation of conformationally modified albumins. Potential role of gp30 and gp18 as novel scavenger receptors.

J. Schnitzer, J. Bravo, 1993, The Journal of biological chemistry.

Caveolae require intact VAMP for targeted transport in vascular endothelium

J. Schnitzer, D. Mcintosh, Deirdre P. Mcintosh, 1999 .

Caveolae require intact VAMP for targeted transport in vascular endothelium.

J. Schnitzer, D. Mcintosh, 1999, American journal of physiology. Heart and circulatory physiology.

Quantitation of specific binding of orosomucoid to cultured microvascular endothelium: role in capillary permeability.

J. Schnitzer, E. Pinney, 1992, The American journal of physiology.

Neutral sphingomyelinase inhibitor scyphostatin prevents and ceramide mimics mechanotransduction in vascular endothelium.

J. Schnitzer, M. Czarny, 2004, American journal of physiology. Heart and circulatory physiology.

Lectin binding to gp60 decreases specific albumin binding and transport in pulmonary artery endothelial monolayers

A. Malik, H. Lum, J. Schnitzer, 1991, Journal of cellular physiology.

A major endothelial plasmalemmal sialoglycoprotein, gp60, is immunologically related to glycophorin.

G. Palade, J. Ulmer, J. Schnitzer, 1990, Proceedings of the National Academy of Sciences of the United States of America.

Antibodies to SPARC inhibit albumin binding to SPARC, gp60, and microvascular endothelium.

P. Oh, J. Schnitzer, 1992, The American journal of physiology.

Specific albumin binding to microvascular endothelium in culture.

G. Palade, J. Schnitzer, W. Carley, 1988, The American journal of physiology.

Analysis of steric partition behavior of molecules in membranes using statistical physics. Application to gel chromatography and electrophoresis.

J. Schnitzer, 1988, Biophysical journal.

T Cell Pathways Involving CTLA4 Contribute To a Model of Acute Lung Injury

S. Makani, P. Finn, D. Perkins, 2010, The Journal of Immunology.

Contribute To a Model of Acute Lung Injury T Cell Pathways Involving CTLA4

S. Makani, P. Finn, D. Perkins, 2022 .

Designed Auto-assembly of Nanostreptabodies for Rapid Tissue-specific Targeting in Vivo*

N. Griffin, P. Oh, J. Schnitzer, 2009, The Journal of Biological Chemistry.

Application of capture-recapture models to estimation of protein count in MudPIT experiments.

J. Koziol, J. Schnitzer, A. Feng, 2006, Analytical chemistry.

Subcellular localization of intracellular protein tyrosine phosphatases in T cells

A. Alonso, T. Mustelin, M. Saxena, 2000, European journal of immunology.

Relationship of 99mTc-MDP uptake to regional osseous circulation in skeletally immature and mature dogs

P. Hoffer, J. Ogden, J. Schnitzer, 1982, Skeletal Radiology.

Immunotargeting and cloning of two CD34 variants exhibiting restricted expression in adult rat endothelia in vivo.

P. Oh, Yan Li, J. Schnitzer, 2009, American journal of physiology. Lung cellular and molecular physiology.

Isolation and partial characterization of the luminal plasmalemma of microvascular endothelium from rat lungs.

B. Jacobson, G. Palade, J. Schnitzer, 1992, European journal of cell biology.

Organized Endothelial Cell Surface Signal Transduction in Caveolae Distinct from Glycosylphosphatidylinositol-anchored Protein Microdomains*

P. Oh, J. Schnitzer, Jun Liu, 1997, The Journal of Biological Chemistry.

Segmental differentiation of permeability, protein glycosylation, and morphology of cultured bovine lung vascular endothelium.

A. Malik, J. Schnitzer, P. del Vecchio, 1994, Biochemical and biophysical research communications.

Targeting caveolae to pump bispecific antibody to TGF-β into diseased lungs enables ultra-low dose therapeutic efficacy

B. Olenyuk, J. Schnitzer, A. Chrastina, 2022, bioRxiv.

Aquaporin-1 in plasma membrane and caveolae provides mercury-sensitive water channels across lung endothelium.

P. Oh, J. Schnitzer, 1996, The American journal of physiology.

Range Charts for Agreement in Measurement Comparison Studies, With Application to Replicate Mass Spectrometry Experiments.

James A Koziol, Jan E Schnitzer, Jingyi Yu, 2008, Journal of proteomics & bioinformatics.

Laser-targeted photosensitizer-induced lung injury: Noninvasive rat model of pulmonary infarction

J. Schnitzer, A. Chrastina, 2012, Experimental lung research.

Endothelial Caveolae Have the Molecular Transport Machinery for Vesicle Budding, Docking, and Fusion Including VAMP, NSF, SNAP, Annexins, and GTPases (*)

P. Oh, J. Schnitzer, J E Schnitzer, 1995, The Journal of Biological Chemistry.

Glycocalyx electrostatic potential profile analysis: ion, pH, steric, and charge effects.

J. Schnitzer, Schnitzer Je, 1988, The Yale journal of biology and medicine.

II. Capsular vaso-mimicry formed by transgenic mammary tumor spheroids implanted ectopically into mouse dorsal skin fold: implications for cellular mechanisms of metastasis

P. Oh, J. Schnitzer, H. Witkiewicz, 2013, F1000Research.

Overcoming key biological barriers to cancer drug delivery and efficacy.

J. Schnitzer, P. H. Faix, Susy M Kim, 2017, Journal of controlled release : official journal of the Controlled Release Society.

Impaired tumor growth, metastasis, angiogenesis and wound healing in annexin A1-null mice

M. Yi, J. Schnitzer, 2009, Proceedings of the National Academy of Sciences.

Caveolae: from basic trafficking mechanisms to targeting transcytosis for tissue-specific drug and gene delivery in vivo.

J. Schnitzer, Jan E. Schnitzer, 2001, Advanced drug delivery reviews.

I. Embryonal vasculature formation recapitulated in transgenic mammary tumor spheroids implanted pseudo-orthotopicly into mouse dorsal skin fold: the organoblasts concept.

P. Oh, J. Schnitzer, H. Witkiewicz, 2013, F1000Research.

Albondin-mediated capillary permeability to albumin. Differential role of receptors in endothelial transcytosis and endocytosis of native and modified albumins.

P. Oh, J. Schnitzer, J E Schnitzer, 1994, The Journal of biological chemistry.

Suppression of tumor growth by designed dimeric epidithiodiketopiperazine targeting hypoxia-inducible transcription factor complex.

Csaba Laszlo, B. Olenyuk, P. Oh, 2013, Journal of the American Chemical Society.

Mapping Accessible Vascular Targets to Penetrate Organs and Solid Tumors

J. Schnitzer, K. Massey, Kerri A. Massey, 2011 .

Systems analysis of endothelial cell plasma membrane proteome of rat lung microvasculature

Yan Li, J. Schnitzer, H. Witkiewicz, 2011, Proteome Science.

Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide

U. Zabel, U. Walter, H. Schmidt, 2002, Nature Cell Biology.

Rapid Mechanotransduction in Situ at the Luminal Cell Surface of Vascular Endothelium and Its Caveolae*

P. Oh, J. Schnitzer, V. Rizzo, 1998, The Journal of Biological Chemistry.

Role of GTP Hydrolysis in Fission of Caveolae Directly from Plasma Membranes

Jan E. Schnitzer, P. Oh, J. Schnitzer, 1996, Science.

Overcoming in vivo barriers to targeted nanodelivery.

Jan E Schnitzer, J. Schnitzer, A. Chrastina, 2011, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

Live dynamic imaging of caveolae pumping targeted antibody rapidly and specifically across endothelium in the lung

P. Oh, Yan Li, J. Schnitzer, 2007, Nature Biotechnology.

Overcoming Key Technological Challenges in Using Mass Spectrometry for Mapping Cell Surfaces in Tissues*

N. Griffin, J. Schnitzer, 2010, Molecular & Cellular Proteomics.

Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling.

G. Garcı́a-Cardeña, W. Sessa, P. Oh, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Targeting and imaging signature caveolar molecules in lungs.

J. Schnitzer, K. Massey, Kerri A. Massey, 2009, Proceedings of the American Thoracic Society.

Vascular proteomic mapping in vivo

J. Schnitzer, A. Simonson, 2007, Journal of thrombosis and haemostasis : JTH.

Enhancing Identifications of Lipid-embedded Proteins by Mass Spectrometry for Improved Mapping of Endothelial Plasma Membranes in Vivo*

Yipeng Wang, N. Griffin, Jingyi Yu, 2009, Molecular & Cellular Proteomics.

In Situ Flow Activates Endothelial Nitric Oxide Synthase in Luminal Caveolae of Endothelium with Rapid Caveolin Dissociation and Calmodulin Association*

P. Oh, J. Schnitzer, D. Mcintosh, 1998, The Journal of Biological Chemistry.

Segregation of heterotrimeric G proteins in cell surface microdomains. G(q) binds caveolin to concentrate in caveolae, whereas G(i) and G(s) target lipid rafts by default.

P. Oh, J. Schnitzer, 2001, Molecular biology of the cell.

Transport Functions of the Glycocalyx, Specific Proteins, and Caveolae in Endothelium

J. Schnitzer, 1998 .

Co-implanting orthotopic tissue creates stroma microenvironment enhancing growth and angiogenesis of multiple tumors

P. Oh, J. Schnitzer, P. Borgstrom, 2013, F1000Research.

Dynamin at the Neck of Caveolae Mediates Their Budding to Form Transport Vesicles by GTP-driven Fission from the Plasma Membrane of Endothelium

P. Oh, J. Schnitzer, D. Mcintosh, 1998, The Journal of cell biology.

Lung Vascular Targeting Using Antibody to Aminopeptidase P: CT-SPECT Imaging, Biodistribution and Pharmacokinetic Analysis

J. Schnitzer, A. Chrastina, P. Valadon, 2010, Journal of Vascular Research.

III. Cellular ultrastructures in situ as key to understanding tumor energy metabolism: biological significance of the Warburg effect

P. Oh, J. Schnitzer, H. Witkiewicz, 2013, F1000Research.

Hierarchical approach to predicting permeation in ion channels.

E. Jakobsson, R. J. Mashl, J. Schnitzer, 2001, Biophysical journal.

Lectin analysis of common glycoproteins detected on the surface of continuous microvascular endothelium in situ and in culture: identification of sialoglycoproteins.

G. Palade, J. Schnitzer, C. Shen, 1990, European journal of cell biology.

Quantitation of regional chondro-osseous circulation in canine tibia and femur.

J. Ogden, J. Schnitzer, T. Light, 1982, The American journal of physiology.

Article Status Summary Referee Responses

P. Oh, J. Schnitzer, H. Witkiewicz, 2022 .

Recruitment of endothelial caveolae into mechanotransduction pathways by flow conditioning in vitro.

P. Davies, C. Morton, J. Schnitzer, 2003, American journal of physiology. Heart and circulatory physiology.

Targeting endothelium and its dynamic caveolae for tissue-specific transcytosis in vivo: A pathway to overcome cell barriers to drug and gene delivery

P. Oh, J. Schnitzer, D. Mcintosh, 2002, Proceedings of the National Academy of Sciences of the United States of America.

NEM inhibits transcytosis, endocytosis, and capillary permeability: implication of caveolae fusion in endothelia.

P. Oh, J. Schnitzer, J. Allard, 1995, The American journal of physiology.

Characterization of acute lung injury in the bleomycin rat model

J. Schnitzer, A. H. Kadam, 2023, Physiological reports.

Common peptide epitopes in glycophorin and the endothelial sialoglycoprotein gp60.

G. Palade, J. Ulmer, J. Schnitzer, 1992, Biochemical and biophysical research communications.

Experimental model of transthoracic, vascular-targeted, photodynamically induced myocardial infarction.

P. Pokreisz, J. Schnitzer, A. Chrastina, 2014, American journal of physiology. Heart and circulatory physiology.

Electrostatic potential and Born energy of charged molecules interacting with phospholipid membranes: calculation via 3-D numerical solution of the full Poisson equation.

J. Schnitzer, K. C. Lambrakis, 1991, Journal of theoretical biology.

Caveolae and cancer.

J. Schnitzer, K. Massey, Kerri A. Massey, 2010, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.

Focusing Target Discovery and Validation Through Proteogenomics and Molecular Imaging

Lucy A. Carver, Jan E. Schnitzer, J. Schnitzer, 2005 .

Where Do We Go From Here? A Framework for Using Susceptible-Infectious-Recovered Models for Policy Making in Emerging Infectious Diseases

J. Hay, J. Schnitzer, N. Zawadzki, 2021, Value in Health.

Tissue-Specific Pharmacodelivery and Overcoming Key Cell Barriers in Vivo: Vascular Targeting of Caveolae

J. Schnitzer, L. A. Carver, 2002 .

Identification of endothelial cell–surface proteins as targets for diagnosis and treatment of disease

D. Stolz, B. Jacobson, J. Schnitzer, 1996, Nature Medicine.

Different ODE models of tumor growth can deliver similar results

J. Koziol, T. Falls, J. Schnitzer, 2020, BMC Cancer.

Tumor Targeting, Trifunctional Dendritic Wedge

B. Olenyuk, P. Oh, J. Schnitzer, 2014, Bioconjugate chemistry.

In vivo proteomic imaging analysis of caveolae reveals pumping system to penetrate solid tumors

P. Oh, Yan Li, J. Schnitzer, 2014, Nature Medicine.

Streamlining biomarker discovery

M. Latterich, J. Schnitzer, 2011, Nature Biotechnology.

Separation of caveolae from associated microdomains of GPI-anchored proteins

P. Oh, J. Schnitzer, J. Schnitzer, 1995, Science.

Caveolae from luminal plasmalemma of rat lung endothelium: microdomains enriched in caveolin, Ca(2+)-ATPase, and inositol trisphosphate receptor.

B. Jacobson, A. Dvorak, P. Oh, 1995, Proceedings of the National Academy of Sciences of the United States of America.

Overcoming Key Technological Challenges in Using Mass Spectrometry for Mapping Cell Surfaces in Tissues*

N. Griffin, J. Schnitzer, 2010, Molecular & Cellular Proteomics.

Neutral sphingomyelinase inhibitor scyphostatin prevents and ceramide mimics mechanotransduction in vascular endothelium.

J. Schnitzer, M. Czarny, 2004, American journal of physiology. Heart and circulatory physiology.

Endothelin Induces Rapid, Dynamin-mediated Budding of Endothelial Caveolae Rich in ET-B*

P. Oh, J. Schnitzer, H. Witkiewicz, 2012, The Journal of Biological Chemistry.

Capsular vaso-mimicry formed by transgenic mammary tumor spheroids implanted ectopically into mouse dorsal skin fold: implications for cellular mechanisms of metastasis [version 2; peer review: 1 approved, 3 approved with reservations]

P. Oh, J. Schnitzer, H. Witkiewicz, 2016 .

Impact of Cisplatin Dosing Regimens on Mammary Tumor Growth in an Animal Model

J. Koziol, T. Falls, J. Schnitzer, 2020, Archives of cancer biology and therapy.

Construction of Metabolically Biotinylated Adenovirus with Deleted Fiber Knob as Targeting Vector

J. Schnitzer, P. Valadon, Yanzheng Liu, 2010, Virology Journal.

International Journal of Nanomedicine Dovepress Iodine-125 Radiolabeling of Silver Nanoparticles for in Vivo Spect Imaging

J. Schnitzer, A. Chrastina, 2022 .