J. Syrjänen

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Clinical presentations and epidemiology of beta-haemolytic streptococcal bacteraemia: a population-based study.

R. Vuento, H. Huhtala, S. Rantala, 2009, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Clinical presentation and outcome of listeriosis in patients with and without immunosuppressive therapy.

P. Ruutu, V. Valtonen, J. Paavonen, 1992, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Concordance between the old and new diagnostic criteria for periprosthetic joint infection

O. Lyytikäinen, J. Syrjänen, R. Huttunen, 2017, Infection.

An outbreak of human metapneumovirus in a rehabilitation center for alcoholics in Tampere, Finland

J. Laine, R. Vuento, Outi K. Laine, 2015, Infectious diseases.

Smoking and the outcome of infection

T. Heikkinen, J. Syrjänen, R. Huttunen, 2011, Journal of internal medicine.

Insulin resistance and the progression of IgA glomerulonephritis.

H. Huhtala, J. Mustonen, A. Pasternack, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Angiotensin-Converting Enzyme Insertion/Deletion Polymorphism and Prognosis of IgA Nephropathy

T. Lehtimäki, T. Koivula, J. Mustonen, 2000, Nephron.

Streptococcus dysgalactiae subsp. equisimilis Bacteremia, Finland, 1995–2004

R. Vuento, S. Rantala, J. Vuopio‐Varkila, 2010, Emerging infectious diseases.

Vascular diseases and their risk factors in IgA nephropathy.

H. Helin, J. Mustonen, A. Pasternack, 2006, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Uric acid correlates with the severity of histopathological parameters in IgA nephropathy.

H. Helin, J. Mustonen, A. Pasternack, 2005, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Polymorphism of the cytokine genes and IgA nephropathy.

T. Lehtimäki, J. Mustonen, A. Pasternack, 2002, Kidney international.

IgA immune responses against acetaldehyde adducts and biomarkers of alcohol consumption in patients with IgA glomerulonephritis.

H. Huhtala, J. Mustonen, A. Pasternack, 2009, Alcoholism, clinical and experimental research.

Hypertriglyceridaemia and hyperuricaemia are risk factors for progression of IgA nephropathy.

J. Mustonen, A. Pasternack, J. Syrjänen, 2000, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Severity of tubulointerstitial inflammation and prognosis in immunoglobulin A nephropathy.

H. Helin, J. Mustonen, A. Pasternack, 2007, Kidney international.

Alcohol Consumption and Kidney Function in IgA Glomerulonephritis

H. Huhtala, J. Mustonen, A. Pasternack, 2009, Nephron Clinical Practice.

Pathogenetic Aspects of IgA Nephropathy

H. Helin, J. Mustonen, J. Syrjänen, 2001, Nephron.

Obesity and the outcome of infection.

J. Syrjänen, R. Huttunen, 2010, The Lancet. Infectious diseases.

Trends in incidence and resistance patterns of Staphylococcus aureus bacteremia*

E. Jokinen, J. Laine, R. Vuento, 2017, Infectious diseases.

Nosocomial bloodstream infections in a Finnish tertiary care hospital: a retrospective cohort study of 2175 episodes during the years 1999–2001 and 2005–2010

O. Lyytikäinen, J. Syrjänen, J. Aittoniemi, 2015, Infectious diseases.

Streptococcus pyogenes bacteraemia, emm types and superantigen profiles

R. Vuento, H. Huhtala, S. Rantala, 2012, European Journal of Clinical Microbiology & Infectious Diseases.

Acute bacterial, nonnecrotizing cellulitis in Finland: microbiological findings.

J. Kere, R. Vuento, J. Vuopio‐Varkila, 2008, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

Inflammatory markers and the progression of IgA glomerulonephritis.

H. Huhtala, J. Mustonen, A. Pasternack, 2007, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Central nervous system complications in patients with bacteremia.

J. Syrjänen, 1989, Scandinavian journal of infectious diseases.

Celiac disease and HLA DQ in patients with IgA nephropathy

K. Kaukinen, J. Partanen, J. Mustonen, 2002, American Journal of Gastroenterology.

Celiac disease and HLA DQ in patients with IgA nephropathy.

K. Kaukinen, J. Partanen, J. Mustonen, 2002 .

Thrombo-embolic complications in bacteraemic infections.

V. Valtonen, J. Syrjänen, A. Kuikka, 1993, European heart journal.

Genetic Susceptibility to Non-Necrotizing Erysipelas/Cellulitis

R. Leinonen, J. Kere, K. Kivinen, 2013, PloS one.

Genetic Susceptibility to Non-Necrotizing Erysipelas / Cellulitis Hannula-Jouppi , Katariina 2013-0220

R. Leinonen, J. Kere, K. Kivinen, 2022 .

Factors predisposing to acute and recurrent bacterial non-necrotizing cellulitis in hospitalized patients: a prospective case-control study.

J. Kere, R. Vuento, H. Huhtala, 2010, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Anticardiolipin response and its association with infections in young and middle‐aged patients with cerebral infarction

O. Vaarala, V. Valtonen, J. Syrjänen, 1988, Acta neurologica Scandinavica.

Nasal nitric oxide is decreased in acute mild COVID-19 and related to viral load

J. Syrjänen, J. Aittoniemi, L. Lehtimäki, 2022, Journal of breath research.

Etiology, clinical course and outcome of healthcare-associated bloodstream infections in patients with hematological malignancies: a retrospective study of 350 patients in a Finnish tertiary care hospital

R. Vuento, M. Sinisalo, O. Lyytikäinen, 2015, Leukemia & lymphoma.

Constant B cell lymphocytosis since early age in a patient with CARD11 mutation: A 20-year follow-up.

J. Saarela, Meri Kaustio, J. Syrjänen, 2016, Clinical immunology.

Polymorphism of the C-reactive protein gene is associated with mortality in bacteraemia

J. Laine, R. Vuento, J. Syrjänen, 2006, Scandinavian journal of infectious diseases.

Infection as a risk factor for cerebral infarction.

J. Syrjänen, 1993, European heart journal.

Vascular diseases and oral infections.

J. Syrjänen, 1990, Journal of clinical periodontology.

Association between cerebral infarction and increased serum bacterial antibody levels in young adults

V. Valtonen, P. Mäkelä, T. Hovi, 1986, Acta neurologica Scandinavica.

Increased bacterial antibody titres and IgA deficiency in epileptic patients.

N. Gilhus, V. Valtonen, J. Syrjänen, 1987, British medical journal.

Plasma Cell-Free DNA Levels Are Elevated in Acute Puumala Hantavirus Infection

A. Vaheri, S. Mäkelä, J. Mustonen, 2012, PloS one.

High pentraxin-3 plasma levels associate with thrombocytopenia in acute Puumala hantavirus-induced nephropathia epidemica

S. Meri, A. Vaheri, S. Mäkelä, 2011, European Journal of Clinical Microbiology & Infectious Diseases.

A Serratia marcescens outbreak in a neonatal intensive care unit was successfully managed by rapid hospital hygiene interventions and screening

R. Vuento, O. Tammela, J. Syrjänen, 2018, Acta paediatrica.

Predictors of mortality in beta-hemolytic streptococcal bacteremia: a population-based study.

R. Vuento, H. Huhtala, S. Rantala, 2009, The Journal of infection.

Comparison of outcome and clinical characteristics of bacteremia caused by methicillin-resistant, penicillin-resistant and penicillin-susceptible Staphylococcus aureus strains

E. Jokinen, J. Laine, R. Vuento, 2017, Infectious diseases.

Population-Based Assessment of Contact Tracing Operations for Coronavirus Disease 2019 in Pirkanmaa Hospital District, Finland

J. Laine, J. Syrjänen, J. Nuorti, 2022, Open forum infectious diseases.

SARS-CoV-2 late shedding may be infectious between immunocompromised hosts

S. Blomqvist, J. Syrjänen, H. Viskari, 2021, Infectious diseases.

Characterization of the clinical and immunological phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations.

William J. Astle, Sri V. V. Deevi, Kenneth G. C. Smith, 2020, The Journal of allergy and clinical immunology.

Methicillin-resistant Staphylococcus aureus epidemic restricted to one health district in Finland: A population-based descriptive study in Pirkanmaa, Finland, years 2001–2011

J. Laine, R. Vuento, J. Syrjänen, 2013, Scandinavian journal of infectious diseases.

Long-term follow up of families with pathogenic NFKB1 variants reveals incomplete penetrance and frequent inflammatory sequelae.

J. Kere, M. Varjosalo, T. Hautala, 2022, Clinical immunology.

Healthcare workers as vectors of infectious diseases

J. Syrjänen, R. Huttunen, 2014, European Journal of Clinical Microbiology & Infectious Diseases.

Recurrent cellulitis with benzathine penicillin prophylaxis is associated with diabetes and psoriasis

J. Kere, A. Aromaa, H. Huhtala, 2013, European Journal of Clinical Microbiology & Infectious Diseases.

Periprosthetic Joint Infections as a Consequence of Bacteremia

A. Eskelinen, J. Syrjänen, R. Huttunen, 2019, Open forum infectious diseases.

Bloodstream infections in acute myeloid leukemia patients treated according to the Finnish Leukemia Group AML-2003 protocol – a prospective nationwide study

E. Jantunen, P. Koistinen, M. Itälä-Remes, 2017, Infectious diseases.

The effect of preoperative oral antibiotic use on the risk of periprosthetic joint infection after primary knee or hip replacement: a retrospective study with a 1-year follow-up.

J. Syrjänen, R. Huttunen, M. Honkanen, 2019, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

The impact of preoperative bacteriuria on the risk of periprosthetic joint infection after primary knee or hip replacement: a retrospective study with a 1-year follow up.

A. Eskelinen, H. Huhtala, J. Syrjänen, 2017, Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases.

Healthcare workers as vectors of infectious diseases

J. Syrjänen, R. Huttunen, 2014, European Journal of Clinical Microbiology & Infectious Diseases.

Predictors of recurrent cellulitis in five years. Clinical risk factors and the role of PTX3 and CRP.

J. Kere, H. Huhtala, J. Syrjänen, 2015, The Journal of infection.

Evidence of streptococcal origin of acute non-necrotising cellulitis: a serological study

J. Syrjänen, J. Aittoniemi, J. Vuopio, 2014, European Journal of Clinical Microbiology & Infectious Diseases.

Fungemia and Other Fungal Infections Associated with Use of Saccharomyces boulardii Probiotic Supplements

R. Vuento, J. Syrjänen, E. Mattila, 2021, Emerging infectious diseases.

Damaging heterozygous mutations in NFKB1 lead to diverse immunologic phenotypes

J. Kere, S. Mustjoki, S. Katayama, 2017, The Journal of allergy and clinical immunology.

Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells

M. Varjosalo, S. Keskitalo, V. Glumoff, 2021, Science Immunology.

Loss-of-function mutation in IKZF2 leads to immunodeficiency with dysregulated germinal center reactions and reduction of MAIT cells

M. Varjosalo, P. Peterson, S. Keskitalo, 2021, Science Immunology.

Running title : Serratia marcescens outbreak in neonates

R. Vuento, O. Tammela, J. Syrjänen, 2017 .

Plasma level of soluble urokinase‐type plasminogen activator receptor as a predictor of disease severity and case fatality in patients with bacteraemia: a prospective cohort study

J. Laine, R. Vuento, H. Huhtala, 2011, Journal of internal medicine.

Obesity and the risk and outcome of infection

J. Syrjänen, R. Huttunen, 2013, International Journal of Obesity.

High pentraxin-3 plasma levels associate with thrombocytopenia in acute Puumala hantavirus-induced nephropathia epidemica

S. Meri, A. Vaheri, S. Mäkelä, 2012, European Journal of Clinical Microbiology & Infectious Diseases.

Enrichment of rare variants in population isolates: single AICDA mutation responsible for hyper-IgM syndrome type 2 in Finland

A. Palotie, K. Porkka, T. Hautala, 2016, European Journal of Human Genetics.

Enrichment of rare variants in population isolates: single AICDA mutation responsible for hyper-IgM syndrome type 2 in Finland

A. Palotie, K. Porkka, T. Hautala, 2016, European Journal of Human Genetics.

Differences in Etiology and Treatment in Scandinavian Countries

J. Mustonen, I. Pörsti, J. Syrjänen, 2016 .

HIGH ACTIVITY OF INDOLEAMINE 2,3 DIOXYGENASE ENZYME PREDICTS DISEASE SEVERITY AND CASE FATALITY IN BACTEREMIC PATIENTS

J. Laine, R. Vuento, H. Huhtala, 2010, Shock.

Apoptosis markers soluble Fas (sFas), Fas Ligand (FasL) and sFas/FasL ratio in patients with bacteremia: a prospective cohort study.

J. Laine, R. Vuento, J. Syrjänen, 2012, The Journal of infection.

Fatal Outcome in Bacteremia is Characterized by High Plasma Cell Free DNA Concentration and Apoptotic DNA Fragmentation: A Prospective Cohort Study

J. Laine, R. Vuento, H. Huhtala, 2011, PloS one.

Acquisition of Complement Factor H Is Important for Pathogenesis of Streptococcus pyogenes Infections: Evidence from Bacterial In Vitro Survival and Human Genetic Association

J. Kere, S. Meri, I. Järvelä, 2012, The Journal of Immunology.

Bacterial Endotoxin Activity in Human Serum Is Associated With Dyslipidemia, Insulin Resistance, Obesity, and Chronic Inflammation

A. Rissanen, J. Kaprio, K. Pietiläinen, 2011, Diabetes Care.

Reduced plasma PCSK9 response in patients with bacteraemia is associated with mortality

Z. Ortutay, M. Pesu, J. Syrjänen, 2019, Journal of internal medicine.

Gene–environment Interaction between MBL2 Genotype and Smoking, and the Risk of Gram‐positive Bacteraemia

J. Laine, R. Vuento, H. Huhtala, 2008, Scandinavian journal of immunology.

Current concepts in the diagnosis of blood stream infections. Are novel molecular methods useful in clinical practice?

R. Vuento, J. Syrjänen, J. Aittoniemi, 2013, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

Preceding infection as an important risk factor for ischaemic brain infarction in young and middle aged patients

M. Kaste, J. Huttunen, V. Valtonen, 1988, British medical journal.

Dental infections in association with cerebral infarction in young and middle‐aged men

M. Kaste, J. Huttunen, V. Valtonen, 1989, Journal of internal medicine.

Case fatality associated with a hypervirulent strain in patients with culture-positive Clostridium difficile infection: a retrospective population-based study.

R. Vuento, P. Tissari, J. Syrjänen, 2012, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

J. Syrjänen, J. Aittoniemi, R. Huttunen, 2017, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

Plasma cell‐free DNA and qSOFA score predict 7‐day mortality in 481 emergency department bacteraemia patients

J. Syrjänen, M. Hurme, J. Aittoniemi, 2018, Journal of internal medicine.

Heparin-binding protein: a potential biomarker in sepsis?

J. Syrjänen, R. Huttunen, 2010, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

High Plasma Level of Long Pentraxin 3 (PTX3) Is Associated with Fatal Disease in Bacteremic Patients: A Prospective Cohort Study

J. Laine, R. Vuento, H. Huhtala, 2011, PloS one.

Response to Agilli and Aydin.

J. Syrjänen, M. Karppelin, 2015, The Journal of infection.

Streptococcus pyogenes bacteraemia, emm types and superantigen profiles

R. Vuento, H. Huhtala, S. Rantala, 2012, European Journal of Clinical Microbiology & Infectious Diseases.

Obesity and nosocomial infections.

J. Syrjänen, R. Huttunen, M. Karppelin, 2013, The Journal of hospital infection.

Healthcare‐associated blood stream infections in hematological patients in Finland during the years 2006‐2016

J. Ollgren, R. Vuento, M. Sinisalo, 2021, European journal of haematology.

Effectiveness of COVID-19 digital proximity tracing app in Finland

J. Syrjänen, J. Nuorti, Pekka Tamminen, 2022, Clinical Microbiology and Infection.

Meticillin-resistant Staphylococcus aureus (MRSA) bacteraemia in Tampere University Hospital: a case-control study, Finland October 2002 to January 2010.

J. Laine, R. Vuento, J. Syrjänen, 2011, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

Obesity and smoking are factors associated with poor prognosis in patients with bacteraemia

Jukka Lumio, Janne Laine, Risto Vuento, 2007, BMC infectious diseases.

Combined interventions are effective in MRSA control

E. Jokinen, J. Laine, R. Vuento, 2015, Infectious diseases.

Alcohol Consumption and Its Influence on the Clinical Picture of Puumala Hantavirus Infection

S. Mäkelä, H. Huhtala, J. Mustonen, 2022, Viruses.

Smoking is associated with aggravated kidney injury in Puumala hantavirus-induced haemorrhagic fever with renal syndrome.

A. Rimpelä, A. Vaheri, O. Vapalahti, 2015, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

The severity of Puumala hantavirus induced nephropathia epidemica can be better evaluated using plasma interleukin-6 than C-reactive protein determinations

S. Mäkelä, H. Huhtala, J. Mustonen, 2010, BMC infectious diseases.

Vitro Survival and Human Genetic Association Infections: Evidence from Bacterial In pyogenes Streptococcus Important for Pathogenesis of Acquisition of Complement Factor H Is

S. Meri, I. Järvelä, J. Syrjänen, 2011 .

Distribution of emm types in invasive and non-invasive group A and G streptococci

R. Vuento, J. Syrjänen, J. Vuopio, 2012, European Journal of Clinical Microbiology & Infectious Diseases.

Presence of Streptococcus pyogenes in the throat in invasive Group A Streptococcal disease: a prospective two-year study in two health districts, Finland

K. Auranen, J. Syrjänen, K. Rantakokko-jalava, 2023, Infectious diseases.

Infectious diseases specialist consultation in Staphylococcus lugdunensis bacteremia

A. Järvinen, J. Syrjänen, E. Forsblom, 2021, PloS one.

Is there a link between infection and infarction?

J. Syrjänen, 1988, Annals of clinical research.

Evidence of streptococcal origin of acute non-necrotising cellulitis: a serological study

J. Kere, J. Syrjänen, J. Aittoniemi, 2015, European Journal of Clinical Microbiology & Infectious Diseases.

Pneumococcal bacteraemia during a recent decade.

V. Valtonen, J. Syrjänen, O. Renkonen, 1992, The Journal of infection.

Clinical course and treatment of IgA nephropathy.

J. Mustonen, A. Pasternack, J. Syrjänen, 2001, Journal of nephrology.

Spa type distribution in MRSA and MSSA bacteremias and association of spa clonal complexes with the clinical characteristics of bacteremia

E. Jokinen, R. Vuento, H. Huhtala, 2018, European Journal of Clinical Microbiology & Infectious Diseases.

High activity of indoleamine 2,3‐dioxygenase is associated with renal insufficiency in Puumala hantavirus induced nephropathia epidemica

A. Vaheri, S. Mäkelä, H. Huhtala, 2011, Journal of medical virology.

ENDOTHELIAL NITRIC OXIDE SYNTHASE G894T (GLU298ASP) POLYMORPHISM IS ASSOCIATED WITH HYPOTENSION IN PATIENTS WITH E. coli BACTEREMIA BUT NOT IN BACTEREMIA CAUSED BY A GRAM-POSITIVE ORGANISM

J. Laine, R. Vuento, H. Huhtala, 2009, Shock.

Acute phase response in cerebral infarction.

V. Valtonen, C. Maury, A. Teppo, 1989, Journal of clinical pathology.

Levofloxacin does not decrease mortality in Staphylococcus aureus bacteraemia when added to the standard treatment: a prospective and randomized clinical trial of 381 patients

Joensuu, Espoo, Helsinki, 2006, Journal of internal medicine.

Endothelial nitric oxide synthase G894T (GLU298ASP) polymorphism is associated with hypotension in patients with E. coli bacteremia but not in bacteremia caused by a gram-positive organism.

J. Laine, R. Vuento, H. Huhtala, 2009 .

NEW RISK-FACTORS FOR STROKE

M. Kaste, M. Partinen, J. Huttunen, 1988 .

Plasma cell‐free DNA and qSOFA score predict 7‐day mortality in 481 emergency department bacteraemia patients

J. Syrjänen, M. Hurme, J. Aittoniemi, 2018, Journal of internal medicine.

Current concepts in the diagnosis of blood stream infections. Are novel molecular methods useful in clinical practice?

R. Vuento, J. Syrjänen, J. Aittoniemi, 2013, International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases.

Acquisition of Complement Factor H Is Important for Pathogenesis of Streptococcus pyogenes Infections: Evidence from Bacterial In Vitro Survival and Human Genetic Association

I. Järvelä, T. Jokiranta, J. Syrjänen, 2012, Journal of Immunology.

Recurrent cellulitis with benzathine penicillin prophylaxis is associated with diabetes and psoriasis

J. Syrjänen, J. Vuopio, K. Hannula-Jouppi, 2012, European Journal of Clinical Microbiology & Infectious Diseases.

Hypogammaglobulinemia with T‐cell defects and autoimmune manifestations associated with chromosome 15q24 microdeletion

S. Rantala, J. Syrjänen, T. Outinen, 2023, Scandinavian Journal of Immunology.

Meticillin-resistant Staphylococcus aureus (MRSA) bacteraemia in Tampere University Hospital: a case-control study, Finland October 2002 to January 2010.

J. Laine, R. Vuento, J. Syrjänen, 2011, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.