D. Hoyer

发表

An overview of FDA-approved new molecular entities: 1827-2013.

M. Kinch, Austin Haynesworth, Sarah L Kinch, 2014, Drug discovery today.

An analysis of original research contributions toward FDA-approved drugs.

M. Kinch, D. Hoyer, Eric Patridge, 2015, Drug discovery today.

Dual Genetic Encoding of Acetyl-lysine and Non-deacetylatable Thioacetyl-lysine Mediated by Flexizyme.

Scott J. Miller, D. Söll, Chenguang Fan, 2016, Angewandte Chemie.

An analysis of FDA-approved drugs: natural products and their derivatives.

M. Kinch, D. Hoyer, Eric Patridge, 2016, Drug discovery today.

An analysis of FDA-approved drugs for cardiovascular diseases.

M. Kinch, D. Hoyer, Y. Surovtseva, 2016, Drug discovery today.

Target selection for FDA-approved medicines.

M. Kinch, D. Hoyer, Eric Patridge, 2015, Drug discovery today.

An analysis of FDA-approved drugs for infectious disease: antibacterial agents.

M. Kinch, D. Hoyer, Eric Patridge, 2014, Drug discovery today.

α-((Tetronoyl)oxy)- and α-((tetramoyl)oxy)methyl ketone inhibitors of the interleukin-1β converting enzyme (ICE)

T. Graybill, C. Prouty, R. Dolle, 1997 .

Structure activity relationships of non-peptide bradykinin B2 receptor antagonists

J. Salvino, R. Dolle, D. Hoyer, 1995 .

A γ-lactam siderophore antibiotic effective against multidrug-resistant Pseudomonas aeruginosa, Klebsiella pneumoniae, and Acinetobacter spp.

R. Bonomo, D. van Duin, K. Hujer, 2021, European journal of medicinal chemistry.

A γ-Lactam Siderophore Antibiotic Effective Against Multidrug-Resistant Gram-Negative Bacilli.

R. Bonomo, D. van Duin, K. Hujer, 2020, Journal of medicinal chemistry.

Development and optimization of a high-throughput screening method utilizing Ancylostoma ceylanicum egg hatching to identify novel anthelmintics

C. Caffrey, T. Yoshino, D. Hoyer, 2019, PloS one.

Effects of the ECE/NEP inhibitor CGS 34225 on the big ET-1-induced pressor response and plasma atrial natriuretic peptide concentration in conscious rats.

D. Hoyer, A. Jeng, P. Savage, 2002, Clinical science.

Macrolides selectively inhibit mutant KCNJ5 potassium channels that cause aldosterone-producing adenoma

R. Lifton, U. Scholl, Junhui Zhang, 2017, The Journal of clinical investigation.

Stereochemistry of the Ph3P-CCl4 mediated cyclization of carboxylic acids and 1,2-amino alcohols (Vorbruggen method)

D. Hoyer, A. Meyers, 1985 .

Asymmetric tandem addition to chiral 1- and 2-substituted naphthalenes. Application to the synthesis of (+)-phyltetralin

G. Roth, D. Hoyer, A. Meyers, 1988 .

A new strategy for selective protein cleavage

Peter G. Schultz, P. Schultz, D. Hoyer, 1990 .

High-throughput screening identifies compounds that protect RPE cells from physiological stressors present in AMD.

L. D. Del Priore, D. Hoyer, S. Noggle, 2019, Experimental eye research.

Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance

J. Merkel, D. Hoyer, Peter C. Gareiss, 2016, Oncotarget.

Identification of Small Molecule Inhibitors of Jumonji AT-rich Interactive Domain 1B (JARID1B) Histone Demethylase by a Sensitive High Throughput Screen*

Alan J. Tackett, A. Tackett, J. Merkel, 2013, The Journal of Biological Chemistry.

Creation of a new class of radiosensitizers for glioblastoma based on the mibefradil pharmacophore

R. Bindra, J. Herrington, R. Sundaram, 2021, Oncotarget.

YU238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-Deficient Tumors

P. Glazer, J. Merkel, D. Hoyer, 2015, Molecular Cancer Research.

Molecular Basis of Purinergic Signal Metabolism by Ectonucleotide Pyrophosphatase/Phosphodiesterases 4 and 1 and Implications in Stroke*♦

D. Braddock, W. Cao, E. M. De La Cruz, 2013, The Journal of Biological Chemistry.

Pyrrolocin A, a 3-Decalinoyltetramic Acid with Selective Biological Activity, Isolated from Amazonian Cultures of the Novel Endophyte Diaporthales sp. E6927E

K. Gustafson, S. Strobel, D. Spakowicz, 2015, Natural product communications.

Phosphorylated WNK kinase networks in recoded bacteria recapitulate physiological function

Farren J. Isaacs, Chad J. Miller, A. Levchenko, 2021, Cell reports.

YU 238259 Is a Novel Inhibitor of Homology-Dependent DNA Repair That Exhibits Synthetic Lethality and Radiosensitization in Repair-De fi cient Tumors

P. Glazer, J. Merkel, D. Hoyer, 2015 .

A history of drug development in four acts.

M. Kinch, D. Hoyer, 2015, Drug discovery today.

Palladium-catalyzed cross-coupling in the synthesis of pyridinyl boxazomycin C analogues.

W. Denny, G. Rewcastle, D. Hoyer, 2005, Journal of Organic Chemistry.

Structural and stereochemical requirements of time-dependent inactivators of the interleukin-1β converting enzyme

Robert E. Miller, T. Graybill, C. Prouty, 1995 .

Macrolides Selectively Inhibit Mutant KCNJ5 Potassium Channels Macrolides Selectively Inhibit Mutant KCNJ5 Potassium Channels that Cause Aldosterone-Producing Adenoma that Cause Aldosterone-Producing Adenoma

R. Lifton, D. Hoyer, L. Abriola, 2022 .

Potent and selective non-peptidic inhibitors of endothelin-converting enzyme-1 with sustained duration of action.

D. Hoyer, Y. Satoh, D. Hoyer, 2000, Journal of medicinal chemistry.

Pyridazinodiazepines as a high-affinity, P2-P3 peptidomimetic class of interleukin-1 beta-converting enzyme inhibitor.

D. Hoyer, T. Graybill, C. Prouty, 1997, Journal of medicinal chemistry.

Design and synthesis of potent thiol-based inhibitors of endothelin converting enzyme-1.

David J. Symonsbergen, D. Hoyer, D. Hoyer, 2000, Bioorganic & medicinal chemistry letters.