A. Gradman

发表

Sudden death during ambulatory monitoring. Clinical and electrocardiographic correlations. Report of a case.

R. Debusk, A. Gradman, P. A. Bell, 1977, Circulation.

Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in-Congestive Heart Failure (MERIT-HF)

Fach, Thilo, D. DeMets, 1999, The Lancet.

Sleep-time blood pressure: a validated therapeutic target.

A. Gradman, 2011, Journal of the American College of Cardiology.

A multicenter, randomized, double-blind, placebo-controlled, 8-week trial of the efficacy and tolerability of once-daily losartan 100 mg/hydrochlorothiazide 25 mg and losartan 50 mg/hydrochlorothiazide 12.5 mg in the treatment of moderate-to-severe essential hypertension.

R. Zeldin, A. Gradman, W. Brady, 2002, Clinical therapeutics.

The New Hypertension Guidelines: Hits and Misses

Sanjiv J. Shah, W. Cushman, S. Nesbitt, 2021 .

Mechanisms and management of hypertensive heart disease: from left ventricular hypertrophy to heart failure.

J. Izzo, A. Gradman, Joseph L Izzo, 2004, The Medical clinics of North America.

Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in-Congestive Heart Failure (MERIT-HF)

Fach, Thilo, D. DeMets, 1999, The Lancet.

Supraventricular Tachycardia in Patients With Right Hemisphere Strokes

R. Lane, G. Schwartz, A. Gradman, 1992, Stroke.

Effects of losartan and captopril on left ventricular volumes in elderly patients with heart failure: results of the ELITE ventricular function substudy.

W. Rand, J. J. Smith, V. Bittner, 2000, American heart journal.

Patients With Right-and Left-Hemisphere Strokes

R. Lane, G. Schwartz, A. Gradman, 2005 .

Renin inhibition in hypertension.

A. Gradman, R. Kad, Alan H Gradman, 2008, Journal of the American College of Cardiology.

Ventricular arrhythmias late after aortic valve replacement and their relation to left ventricular performance.

B. Zaret, A. Geha, R. Shaw, 1981, The American journal of cardiology.

New therapeutic perspectives with clevidipine: an ultra-short-acting intravenous Ca2+ channel blocker

A. Gradman, Yoel Vivas, 2007, Expert opinion on investigational drugs.

Antiarrhythmic drug effect assessed from ventricular arrhythmia reduction in the ambulatory electrocardiogram and treadmill test: comparison of propranolol, procainamide and quinidine.

R. Winkle, A. Gradman, J. Fitzgerald, 1978, The American journal of cardiology.

Suppression of Premature Ventricular Contractions by Acebutolol

P. Meffin, R. Winkle, D. Harrison, 1977, Circulation.

Suppression ofPremature Ventricular Contractions byAcebutolol

R. Winkle, A. Gradman, P. A. Bell, 1976 .

Variability of repetitive arrhythmia formation in patients with chronic ventricular arrhythmia.

A. Gradman, J. Lewis, M. A. Harbison, 1981, The American journal of cardiology.

New drugs for hypertension: What do they offer?

A. Gradman, Yoel Vivas, 2006, Current hypertension reports.

Underutilization and clinical benefits of angiotensin-converting enzyme inhibitors in patients with asymptomatic left ventricular dysfunction.

A. Gradman, M. Kermani, A. Dua, 2000, The American journal of cardiology.

Current concepts: renin inhibition in the treatment of hypertension.

A. Gradman, R. Kad, R. Pinto, 2008, Current opinion in pharmacology.

Managing cardiovascular and renal risk: the potential of direct renin inhibition

P. Sever, M. Azizi, A. Gradman, 2009, Journal of the renin-angiotensin-aldosterone system : JRAAS.

Evolving understanding of the renin-angiotensin-aldosterone system: pathophysiology and targets for therapeutic intervention.

A. Gradman, 2009, American heart journal.

Lisinopril dose-response relationship in essential hypertension.

A. Leon, A. Gradman, V. Cirillo, 1989, British journal of clinical pharmacology.

A perspective on the 2013 US guidelines for hypertension: Where does the so called “Evidence based approach” fall short?

A. Gradman, 2015 .

Recent clinical trials.

J. Basile, A. Gradman, 2014, Journal of the American Society of Hypertension : JASH.

Antihypertensive Efficacy of Candesartan in Comparison to Losartan: The CLAIM Study

E. Michelson, G. Bakris, M. Munger, 2001, Journal of clinical hypertension.

Predictors of mortality in patients with heart failure.

P. Deedwania, A. Gradman, 1994, Cardiology clinics.

Combination therapy for hypertension

G. Bakris, J. Basile, A. Gradman, 2005 .

Hypertension and diastolic heart failure

A. Gradman, J. Travis Wilson, 2009, Current cardiology reports.

Antiarrhythmic Drug Effect Assessed from Ventricular Arrhythmia Reduction in the Ambulatory Electrocardiogram and Treadmill Test: Comparison of Propranolol, Procainamide and Quinidine

R. Winkle, A. Gradman, P. A. Bell, 1979 .

Plasma renin and the antihypertensive effect of the orally active renin inhibitor aliskiren in clinical hypertension

R. Schmieder, R. Lins, A. Gradman, 2007, International journal of clinical practice.

Predictors of total mortality and sudden death in mild to moderate heart failure. Captopril-Digoxin Study Group.

B. Pitt, R. Cody, B. Massie, 1989, Journal of the American College of Cardiology.

Consensus recommendations for the management of chronic heart failure: Introduction

Thomas D. Giles, William T. Abraham, John B. Kostis, 1999 .

Hemodynamic effects of the vascular selective calcium antagonist felodipine in patients with impaired left ventricular function.

A. Gradman, 1992, American heart journal.

Effect of nesiritide on renal function in patients admitted for decompensated heart failure.

A. Gradman, V. Srinivasan, S. Arora, 2007, QJM : monthly journal of the Association of Physicians.

Effect of Intracoronary Nicardipine on Cardiac Enzymes After Elective Percutaneous Coronary Intervention

A. Gradman, S. Arora, V. Srinivasan, 2009, Clinical cardiology.

Direct renin inhibition: An update

A. Gradman, R. Pinto, 2009, Current hypertension reports.

9.9 Aliskiren, a Novel Renin Inhibitor, is Well Tolerated and Has Sustained BP-Lowering Effects Alone or in Combination with HCTZ During Long-Term (52 Weeks) Treatment of Hypertension

D. Sica, A. Gradman, O. Lederballe, 2007 .

Lack of correlation between clinic and 24 hour ambulatory blood pressure in subjects participating in a therapeutic drug trial.

A. Gradman, M. Germain, P. Pangan, 1989, Journal of clinical epidemiology.

Double-blind evaluation of the dose-response relationship of amlodipine in essential hypertension.

J. Mehta, D. Nash, W. T. Garland, 1993, American heart journal.

A quarter-dose quadpill for initial treatment of hypertension

A. Gradman, 2017, The Lancet.

Monitoring Blood ressure

A. Gradman, M. Buskirk, 2016 .

High dose propranolol in the treatment of angina pectoris: relationship of dose to blood levels and hemodynamic consequences.

B. Zaret, A. Gradman, A. Ross, 1980, The Yale journal of biology and medicine.

Techniques of blood pressure monitoring during exercise.

A. Gradman, 1985, Chest.

Vaccination: A novel strategy for inhibiting the renin-angiotensin-aldosterone system

A. Gradman, R. Pinto, 2008, Current hypertension reports.

Cardiac effects of cocaine: a review.

A. Gradman, 1988, The Yale journal of biology and medicine.

Optimal blood pressure targets in older adults: how low is low enough?

A. Gradman, 2014, Journal of the American College of Cardiology.

Combined alpha/beta-blockade versus beta 1-selective blockade in essential hypertension in black and white patients.

E. McCarthy, R. Townsend, L. Katz, 1990, Clinical pharmacology and therapeutics.

Comparative effects of candesartan cilexetil and losartan in patients with systemic hypertension. Candesartan Versus Losartan Efficacy Comparison (CANDLE) Study Group.

E. Michelson, P. Deedwania, A. Lewin, 1999, Heart disease.

Comparison of Two Strategies for Intensifying Antihypertensive Treatment Low-Dose Combination (Enalapril 1 Felodipine ER) Versus Increased Dose of Monotherapy (Enalapril)

W. Elliott, A. Gradman, M. Klibaner, 1999 .

Cardiovascular surgical outcomes in patients with the antiphospholipid syndrome--a case-series.

A. Gradman, Yoel Vivas, D. Haybron, 2007, Heart, lung & circulation.

Aliskiren, a Novel Orally Effective Renin Inhibitor, Provides Dose-Dependent Antihypertensive Efficacy and Placebo-Like Tolerability in Hypertensive Patients

R. Schmieder, R. Lins, A. Gradman, 2005, Circulation.

Aliskiren Monotherapy Does Not Cause Paradoxical Blood Pressure Rises: Meta-Analysis of Data From 8 Clinical Trials

A. Stanton, R. Schmieder, R. Sarangapani, 2010, Hypertension.

Hypertension and ischemia: evolving concepts.

A. Gradman, 1992, Journal of the American College of Cardiology.

A comparison of once daily and twice daily antihypertensive therapy with enalapril using noninvasive ambulatory BP monitoring

A. Gradman, C. O'Keefe, 1984 .

Comparative effects of therapy with captopril and digoxin in patients with mild to moderate heart failure. The Captopril-Digoxin Multicenter Research Group.

M. Wilén, J. Cohn, E. Rapaport, 1988, JAMA.

The use of vasoactive therapy for acute decompensated heart failure: hemodynamic and renal considerations.

A. Gradman, D. Traub, 2007 .

The efficacy of aliskiren, a direct renin inhibitor, in the treatment of hypertension.

A. Gradman, D. Traub, 2007, Reviews in cardiovascular medicine.

Reducing Radiocontrast Use in the Cardiac Catheterization Laboratory—A Behavioral Modification Approach

A. Gradman, V. Srinivasan, A. T. Khawaja, 2004, Quality management in health care.

Combined α/β‐blockade versus β1‐selective blockade in essential hypertension in black and white patients

E. McCarthy, R. Townsend, L. Katz, 1990 .

Difficult-to-Treat or Resistant Hypertension: Etiology, Pathophysiology, and Innovative Therapies

V. Papademetriou, A. Gradman, K. Tsioufis, 2011, International journal of hypertension.

Antihypertensive efficacy and safety of losartan alone and in combination with hydrochlorothiazide in adult African Americans with mild to moderate hypertension.

W. Kraus, M. Alderman, E. Saunders, 2001, Clinical therapeutics.

Combination Therapy in Hypertension

G. Bakris, J. Basile, A. Gradman, 2011, Journal of clinical hypertension.

ASH Position Article Combination therapy in hypertension

G. Bakris, J. Basile, A. Gradman, 2010 .

Combination therapy in hypertension.

G. Bakris, J. Basile, A. Gradman, 2010, Journal of the American Society of Hypertension : JASH.

Combined enalapril and felodipine extended release (ER) for systemic hypertension. Enalapril-Felodipine ER Factorial Study Group.

J. Robbins, N. Cutler, R. Weiss, 1997, The American journal of cardiology.

The role of denial in recovery from coronary heart disease.

G. Schwartz, S. Warrenburg, A. Fontana, 1987, Psychosomatic medicine.

Allergic angina and allergic myocardial infarction: a new twist on an old syndrome.

A. Gradman, N. Kounis, L. Nikolaidis, 2002, The Canadian journal of cardiology.

Initial Combination Therapy Reduces the Risk of Cardiovascular Events in Hypertensive Patients: A Matched Cohort Study

H. Parise, A. Gradman, M. Duh, 2013, Hypertension.

Combination Angiotensin Receptor Blocker/Hydrochlorothiazide as Initial Therapy in the Treatment of Patients With Severe Hypertension

A. Gradman, L. Demopoulos, R. Mukherjee, 2004, Journal of clinical hypertension.

Left anterior descending coronary artery to right ventricular fistula complicating coronary stenting.

A. Gradman, Denes Korpas, R. Lindsey, 2002, The Journal of invasive cardiology.

Addictive Disorders in Cardiovascular Medicine

A. Gradman, Nosheen Javed, 2010 .

Combination therapy in hypertension.

S. Oparil, G. Bakris, H. Black, 2010, Journal of the American Society of Hypertension : JASH.

A Call for Appropriate Evidence and Outcomes-Based Use and Measurement of Anticoagulation for Atrial Fibrillation: Moving the Population Towards Improved Health Via Multiple Stakeholders.

F. Shaya, V. Chirikov, J. Stevenson, 2015, Journal of managed care & specialty pharmacy.

Role of Angiotensin II Type 1 Receptor Antagonists in the Treatment of Hypertension in Patients Aged ≥65 Years

A. Gradman, 2009, Drugs & aging.

LCZ696: The Next Step in Improving RAS Inhibition?

A. Gradman, 2015, Current Hypertension Reports.

Combined renin-angiotensin-aldosterone system inhibition in patients with chronic heart failure secondary to left ventricular systolic dysfunction.

V. Papademetriou, A. Gradman, 2009, American heart journal.

Treating patients for cardiovascular protection: combination therapy to achieve complete renin-angiotensin system blockade.

A. Gradman, 2007, Preventive cardiology.

Chapter 80 – Angiotensin-Converting Enzyme Inhibitors

A. Gradman, D. Traub, 2007 .

Hypertension in the elderly: Age- and disease-related complications and therapeutic implications

J. Fleg, E. Lakatta, Jerome D. Cohen, 1993, Cardiovascular Drugs and Therapy.

Managing High‐Risk Patients With Hypertension: Focus on the Renin‐Angiotensin System

A. Gradman, 2004, Journal of clinical hypertension.

A randomized, placebo-controlled, double-blind, parallel study of various doses of losartan potassium compared with enalapril maleate in patients with essential hypertension.

D. Snavely, E. Nelson, A. Gradman, 1995, Hypertension.

AT1-receptor blockers: differences that matter

A. Gradman, 2002, Journal of Human Hypertension.

Effects of once-daily benazepril therapy on exercise tolerance and manifestations of chronic congestive heart failure. The Benazepril Heart Failure Study Group.

A. Gradman, A. Kapoor, H. Colfer, 1992, The American journal of cardiology.

Effects of candesartan cilexetil in patients with severe systemic hypertension. Candesartan Cilexetil Study Investigators.

S. Oparil, E. Michelson, J. Levine, 1998, The American journal of cardiology.

Beneficial Effects of Pimobendan on Exercise Tolerance and Qualit of Life in Patients With Heart Failure: Results of a Multicenter Trial

M. Brodsky, P. Rahko, J. Cohn, 1992 .

Adding nebivolol to ongoing antihypertensive therapy improves blood pressure and response rates in patients with uncontrolled stage I–II hypertension

A. Gradman, D. Smith, J. Neutel, 2010, Journal of Human Hypertension.

The Elusive Search for Optimal Blood Pressure Targets

A. Gradman, 2017, Current Hypertension Reports.

Blood pressure target values: the saga continues.

A. Gradman, 2016, European heart journal.

What should goal BP and ideal agent(s) be to prevent stroke in patients with hypertension

A. Gradman, 2015 .

Efficacy and safety of nebivolol and valsartan as fixed-dose combination in hypertension: a randomised, multicentre study

Wei Chen, J. Basile, T. Giles, 2014, The Lancet.

Efficacy, safety and tolerability of aliskiren, a direct renin inhibitor, in women with hypertension: a pooled analysis of eight studies

M. Weir, A. Gradman, D. Keefe, 2010, Journal of Human Hypertension.

Effects of oral digoxin on ventricular ectopy and its relation to left ventricular function.

B. Zaret, A. Gradman, H. Berger, 1983, The American journal of cardiology.

From left ventricular hypertrophy to congestive heart failure: management of hypertensive heart disease.

A. Gradman, Alan H Gradman, Fadi Alfayoumi, 2006, Progress in cardiovascular diseases.

Evolving strategies for the use of combination therapy in hypertension

A. Gradman, Celso Acevedo, 2002, Current hypertension reports.

Assessment of once-daily eprosartan, an angiotensin II antagonist, in patients with systemic hypertension. Eprosartan Study Group.

W. White, A. Gradman, H. Punzi, 1999, Clinical therapeutics.

Rationale for Triple‐Combination Therapy for Management of High Blood Pressure

A. Gradman, 2010, Journal of clinical hypertension.

Strategies for combination therapy in hypertension

A. Gradman, Alan H Gradman, 2012, Current opinion in nephrology and hypertension.

Situational panic attacks. Behavioral, physiologic, and biochemical characterization.

S. Woods, D. Charney, G. Heninger, 1987, Archives of general psychiatry.

Comparison of sustained-release formulations of nicardipine and verapamil for mild to moderate systemic hypertension.

W. Frishman, A. Gradman, K. Friday, 1992, The American journal of cardiology.

The no-reflow phenomenon: epidemiology, pathophysiology, and therapeutic approach.

A. Gradman, V. Srinivasan, Fadi Alfayoumi, 2005, Reviews in cardiovascular medicine.

INCIDENCE OF BLOOD PRESSURE RISES WITH ALISKIREN AND OTHER ANTIHYPERTENSIVE AGENTS IN PATIENTS WITH HYPERTENSION

A. Stanton, R. Schmieder, R. Sarangapani, 2009 .

Aliskiren, a novel orally effective renin inhibitor, provides antihypertensive efficacy and placebo-like tolerability similar to an at1-receptor blocker in hypertensive patients

R. Schmieder, R. Lins, A. Gradman, 2004 .

Tolerability profile of tasosartan, a long-acting angiotensin II AT1 receptor blocker, in the treatment of patients with essential hypertension

S. Oparil, V. Papademetriou, A. Gradman, 1997 .

Additivity of nebivolol/valsartan single‐pill combinations versus other single‐pill combinations for hypertension

A. Gradman, J. Neutel, H. Punzi, 2017, Journal of clinical hypertension.

Hepatitis C virus-associated pericardial effusion and tamponade in a liver transplant recipient.

A. Gradman, L. Nikolaidis, L. Friedlander, 2004, The Canadian journal of cardiology.

Long-term benefits of angiotensin II blockade: is the consensus changing?

A. Gradman, 1999, The American journal of cardiology.

Comparison of two strategies for intensifying antihypertensive treatment: low-dose combination (enalapril + felodipine ER) versus increased dose of monotherapy (enalapril). LEVEL (Lexxel vs Enalapril) Study Group.

W. Elliott, C. Hwang, A. Gradman, 1999, American journal of hypertension.

Long-term efficacy, tolerability, and safety of the combination of enalapril and felodipine ER in the treatment of hypertension

E. Michelson, J. Robbins, N. Cutler, 1998 .

Combination Therapy in Hypertension

G. Bakris, J. Basile, A. Gradman, 2011, Journal of clinical hypertension.

Rapid progression in valvular aortic stenosis.

A. Gradman, 1979, Chest.

Is addition of vasodilators to loop diuretics of value in the care of hospitalized acute heart failure patients? Real-world evidence from a retrospective analysis of a large United States hospital database.

A. Gradman, F. Vekeman, M. Duh, 2014, Journal of cardiac failure.

Long-Term Safety and Tolerability of the Oral Direct Renin Inhibitor Aliskiren with Optional Add-On Hydrochlorothiazide in Patients with Hypertension

D. Sica, A. Gradman, O. Lederballe, 2011, Clinical drug investigation.

Combination therapy in hypertension.

G. Bakris, J. Basile, A. Gradman, 2010, Journal of the American Society of Hypertension : JASH.

Consensus recommendations for the management of chronic heart failure: Introduction

R. Falk, G. Fonarow, P. Kowey, 1999 .

Ambulatory electrocardiographic correlates of ventricular inducibility during programmed electrical stimulation.

A. Gradman, W. Batsford, Linda Leon, 1985, Journal of the American College of Cardiology.