S. Blain

发表

TGFbeta signaling in growth control, cancer, and heritable disorders.

J. Massagué, R. Lo, S. Blain, 2000, Cell.

TGFβ Signaling in Growth Control, Cancer, and Heritable Disorders

J. Massagué, R. Lo, S. Blain, 2000, Cell.

mTFE3, an X-linked transcriptional activator containing basic helix-loop-helix and zipper domains, utilizes the zipper to stabilize both DNA binding and multimerization

D. Ward, K. Calame, S. Artandi, 1992, Molecular and cellular biology.

Chk1 has an essential role in the survival of differentiated cortical neurons in the absence of DNA damage

S. Blain, Weizhen Ye, 2011, Apoptosis.

p27Kip1 Inhibits Cyclin D-Cyclin-Dependent Kinase 4 by Two Independent Modes

R. P. Fisher, S. Larochelle, S. Blain, 2008, Molecular and Cellular Biology.

The Kinase-Dependent and Independent Functions of Cdk4 and Cdk6 Regulate Continuous Proliferation and the Exit From Quiescence Differently

S. Blain, Sarah E. Nataraj, 2020, bioRxiv.

p27 as a target for cancer therapeutics.

C. Cordon-Cardo, H. Scher, A. Koff, 2003, Cancer cell.

Macrophage Inhibitory Factor-1 (MIF-1) controls the plasticity of multiple myeloma tumor cells

S. Blain, J. Gonsky, D. Joseph, 2018, PloS one.

Assays for retroviral reverse transcriptase.

S. Goff, A. Telesnitsky, S. Blain, 1995, Methods in enzymology.

Differential Modiﬁcation of p27 Kip1 Controls Its Cyclin D-cdk4 Inhibitory Activity (cid:1) †

S. Blain, A. Ray, Melissa K. James, 2007 .

Inflammatory Mediators of Esophagitis Alter p27Kip1 Expression in Esophageal Epithelial Cells

F. Gress, S. Blain, W. Treem, 2010, Journal of pediatric gastroenterology and nutrition.

Nuclease activities of Moloney murine leukemia virus reverse transcriptase. Mutants with altered substrate specificities.

S. Goff, S. Blain, 1993, The Journal of biological chemistry.

Differential Effects of Moloney Murine Leukemia Virus Reverse Transcriptase Mutations on RNase H Activity in Mg and Mn(*)

S. Goff, S. Blain, 1996, The Journal of Biological Chemistry.

Reversion of a Moloney murine leukemia virus RNase H mutant at a second site restores enzyme function and infectivity

S. Goff, W. Hendrickson, S. Blain, 1995, Journal of virology.

Switching cyclin D-Cdk4 kinase activity on and off

S. Blain, 2008, Cell cycle.

Differential Interaction of the Cyclin-dependent Kinase (Cdk) Inhibitor p27Kip1 with Cyclin A-Cdk2 and Cyclin D2-Cdk4*

J. Massagué, S. Blain, J Massagué, 1997, The Journal of Biological Chemistry.

Sustained proliferation in cancer: Mechanisms and novel therapeutic targets.

Mark A Feitelson, Alan Bilsland, Amr Amin, 2015, Seminars in cancer biology.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Gloria S. Huang, Rob J. Kulathinal, C. Smythe, 2015, Seminars in cancer biology.

Tyrosine Phosphorylation of the p21 Cyclin-dependent Kinase Inhibitor Facilitates the Development of Proneural Glioma*

A. Koff, S. Blain, D. Ciznadija, 2012, The Journal of Biological Chemistry.

S phase entry causes homocysteine-induced death while ataxia telangiectasia and Rad3 related protein functions anti-apoptotically to protect neurons.

S. Blain, Weizhen Ye, 2010, Brain : a journal of neurology.

The Ongoing Search for Biomarkers of CDK4/6 Inhibitor Responsiveness in Breast Cancer

S. Blain, S. Schoninger, 2020, Molecular Cancer Therapeutics.

Different Sensitivity of the Transforming Growth Factor-β Cell Cycle Arrest Pathway to c-Myc and MDM-2*

J. Massagué, S. Blain, 2000, The Journal of Biological Chemistry.

Myc Downregulation by Transforming Growth Factor β Required for Activation of the p15Ink4b G1 Arrest Pathway

J. Massagué, S. Blain, B. Warner, 1999, Molecular and Cellular Biology.

Effects on DNA synthesis and translocation caused by mutations in the RNase H domain of Moloney murine leukemia virus reverse transcriptase

S. Goff, S. Blain, 1995, Journal of virology.

Defects in Moloney murine leukemia virus replication caused by a reverse transcriptase mutation modeled on the structure of Escherichia coli RNase H

S. Goff, A. Telesnitsky, S. Blain, 1992, Journal of virology.

Brk/Protein Tyrosine Kinase 6 Phosphorylates p27KIP1, Regulating the Activity of Cyclin D–Cyclin-Dependent Kinase 4

A. Tyner, R. Wagner, B. Asbach, 2015, Molecular and Cellular Biology.

Differential Modification of p27Kip1 Controls Its Cyclin D-cdk4 Inhibitory Activity

S. Blain, A. Ray, Melissa K. James, 2007, Molecular and Cellular Biology.

Breast cancer banishes p27 from nucleus

J. Massagué, S. Blain, 2002, Nature Medicine.

NP-ALT, a Liposomal:Peptide Drug, Blocks p27Kip1 Phosphorylation to Induce Oxidative Stress, Necroptosis, and Regression in Therapy-Resistant Breast Cancer Cells

Yun Wu, Jonathan Somma, S. Blain, 2021, Molecular Cancer Research.

TGF b Signaling in Growth Control

J. Massagué, R. Lo, S. Blain, 2000 .

Tyrosine Phosphorylation of p27Kip1 Correlates with Palbociclib Responsiveness in Breast Cancer Tumor Cells Grown in Explant Culture

Usha Govindarajulu, Jonathan Somma, S. Blain, 2018, Molecular Cancer Research.

Dual Inhibition of CDK4 and CDK2 via Targeting p27 Tyrosine Phosphorylation Induces a Potent and Durable Response in Breast Cancer Cells

Jonathan Somma, S. Blain, S. Gottesman, 2018, Molecular Cancer Research.

Designing a broad-spectrum integrative approach for cancer prevention and treatment.

Gloria S. Huang, Rob J. Kulathinal, C. Smythe, 2015, Seminars in Cancer Biology.

A cyclin D-CDK6 dimer helps to reshuffle cyclin-dependent kinase inhibitors (CKI) to overcome TGF-beta-mediated arrest and maintain CDK2 activity

S. Blain, Sarah E. Nataraj, 2021, Cell cycle.