C. Hart

发表

Thiazolidinediones as anti-cancer agents.

J. Roman, C. Blanquicett, C. Hart, 2008, Cancer therapy.

Peroxisome proliferator-activated receptor-γ enhances human pulmonary artery smooth muscle cell apoptosis through microRNA-21 and programmed cell death 4.

B. Kang, T. Murphy, C. Hart, 2017, American journal of physiology. Lung cellular and molecular physiology.

Nitric oxide decreases the stability of DMPO spin adducts.

G. Buettner, K. Reszka, B. Britigan, 2006, Nitric oxide : biology and chemistry.

The PPARgamma ligand, rosiglitazone, reduces vascular oxidative stress and NADPH oxidase expression in diabetic mice.

P. Thulé, C. Hart, Jinah Hwang, 2007, Vascular pharmacology.

Peroxisome proliferator-activated receptor-gamma ligands regulate endothelial membrane superoxide production.

K. Griendling, B. Lassègue, S. Dikalov, 2005, American journal of physiology. Cell physiology.

Is peroxisome proliferator-activated receptor gamma (PPARγ) a therapeutic target for the treatment of pulmonary hypertension?

C. Hart, D. Green, R. Sutliff, 2011, Pulmonary circulation.

PPARγ as a potential therapeutic target in pulmonary hypertension

B. Kang, C. Hart, R. Sutliff, 2010, Therapeutic advances in respiratory disease.

Rosiglitazone attenuates chronic hypoxia-induced pulmonary hypertension in a mouse model.

C. Hart, D. Kleinhenz, R. Sutliff, 2010, American journal of respiratory cell and molecular biology.

PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B.

T. Murphy, Xianghuai Lu, C. Hart, 2010, American journal of physiology. Lung cellular and molecular physiology.

PPARγ regulates hypoxia‐induced Nox4 expression in human pulmonary artery smooth muscle cells through NF‐κB

T. Murphy, Xianghuai Lu, C. Hart, 2010 .

Thrombin receptor activating peptides induce Ca2+ mobilization, barrier dysfunction, prostaglandin synthesis, and platelet‐derived growth factor mRNA expression in cultured endothelium

J. Aschner, C. Hart, Joe G. N. Garcia, 1993, Journal of cellular physiology.

Nitric oxide in adult lung disease.

C. Hart, 1999, Chest.

PPAR gamma attenuates hypoxia-induced hypertrophic transcriptional pathways in the heart

B. Kang, J. Calvert, C. Hart, 2022 .

Polymerase Delta Interacting Protein 2 Sustains Vascular Structure and Function

W. R. Taylor, K. Griendling, A. Amanso, 2013, Arteriosclerosis, thrombosis, and vascular biology.

Peroxisome Proliferator‐Activated Receptor &ggr; Regulates the V‐Ets Avian Erythroblastosis Virus E26 Oncogene Homolog 1/microRNA‐27a Axis to Reduce Endothelin‐1 and Endothelial Dysfunction in the Sickle Cell Mouse Lung

B. Kang, T. Murphy, C. Hart, 2017, American journal of respiratory cell and molecular biology.

Hepatic insulin gene therapy prevents deterioration of vascular function and improves adipocytokine profile in STZ-diabetic rats.

P. Thulé, C. Hart, D. Olson, 2006, American journal of physiology. Endocrinology and metabolism.

Nitric oxide attenuates hydrogen peroxide-mediated injury to porcine pulmonary artery endothelial cells.

C. Hart, M. Gupta, V. Evanoff, 1997, The American journal of physiology.

Chronic Hypoxia Promotes Pulmonary Artery Endothelial Cell Proliferation through H2O2-Induced 5-Lipoxygenase

B. Kang, T. Murphy, C. Hart, 2014, PloS one.

Hypoxia downregulates PPARγ via an ERK1/2-NF-κB-Nox4-dependent mechanism in human pulmonary artery smooth muscle cells.

T. Murphy, Xianghuai Lu, C. Hart, 2013, Free radical biology & medicine.

hypoxia-induced endothelin signaling in vitro and in vivo ligand rosiglitazone attenuates γ

B. Kang, T. Murphy, C. Hart, 2016 .

Peroxisome Proliferator-Activated Receptor γ and microRNA 98 in Hypoxia-Induced Endothelin-1 Signaling.

B. Kang, T. Murphy, C. Hart, 2016, American journal of respiratory cell and molecular biology.

Pseudomonas aeruginosa Induced Host Epithelial Cell Mitochondrial Dysfunction

J. Goldberg, Michael Koval, C. Hart, 2019, Scientific Reports.

Effects of Dietary Decosahexaenoic Acid (DHA) on eNOS in Human Coronary Artery Endothelial Cells

C. L. Stebbins, C. Hart, A. Knowlton, 2008, Journal of cardiovascular pharmacology and therapeutics.

Chronic ethanol exposure stimulates endothelial cell nitric oxide production through PI-3 kinase-and hsp90-dependent mechanisms.

C. Hart, H. L. Rupnow, John A. Polikandriotis, 2005, Alcoholism, clinical and experimental research.

Peroxisome Proliferator-Activated Receptor &ggr; Ligands Increase Release of Nitric Oxide From Endothelial Cells

J. Roman, C. Hart, S. Roser, 2003, Arteriosclerosis, thrombosis, and vascular biology.

From Endothelial Cells Ligands Increase Release of Nitric Oxide γ Peroxisome Proliferator-Activated Receptor

J. Roman, C. Hart, S. Roser, 2002 .

Disruption of endothelial peroxisome proliferator-activated receptor-gamma reduces vascular nitric oxide production.

J. Ritzenthaler, C. Hart, D. Archer, 2009, American journal of physiology. Heart and circulatory physiology.

Nicotine Stimulates Nerve Growth Factor in Lung Fibroblasts through an NFκB-Dependent Mechanism

A. Fitzpatrick, C. Hart, K. Crothers, 2014, PloS one.

The Peroxisome Proliferator Activated Receptor Gamma (PPARγ) Ligand Rosiglitazone Modulates Bronchoalveolar Lavage Levels of Leptin, Adiponectin, and Inflammatory Cytokines in Lean and Obese Mice

M. Rojas, C. Hart, F. Holguin, 2007, Lung.

H2O2causes endothelial barrier dysfunction without disrupting the arginine-nitric oxide pathway.

C. Hart, Mahesh P. Gupta, H. Steinberg, 1998, American journal of physiology. Lung cellular and molecular physiology.

H2O2 causes endothelial barrier dysfunction without disrupting the arginine-nitric oxide pathway.

C. Hart, M. Gupta, H. Steinberg, 1998, The American journal of physiology.

Oxidized low density lipoprotein-mediated activation of phospholipase D in smooth muscle cells: a possible role in cell proliferation and atherogenesis.

V. Natarajan, W. M. Scribner, S. Parthasarathy, 1995, Journal of lipid research.

Endothelial cell monolayer dysfunction caused by oxidized low density lipoprotein: attenuation by oleic acid.

C. Hart, Joe G. N. Garcia, J. Garcia, 1997, Prostaglandins, leukotrienes, and essential fatty acids.

PPARγ: A Novel Molecular Target in Lung Disease

P. Sime, C. Hart, Raju C Reddy, 2015 .

UPR modulation of host immunity by P. aeruginosa in cystic fibrosis.

J. Goldberg, A. Stecenko, Michael Koval, 2020, Clinical science.

Redox Biology of Peroxisome Proliferator-Activated Receptor-γ in Pulmonary Hypertension.

C. Hart, R. Sutliff, V. Tseng, 2019, Antioxidants & redox signaling.

Role of 8-epi PGF2alpha, 8-isoprostane, in H2O2-induced derangements of pulmonary artery endothelial cell barrier function.

E. Mohler, C. Hart, M. Gupta, 1998, Prostaglandins, leukotrienes, and essential fatty acids.

Oleic acid supplementation reduces oxidant‐mediated dysfunction of cultured porcine pulmonary artery endothelial cells

C. Hart, Joe G. N. Garcia, C. Patterson, 1993, Journal of cellular physiology.

Oxidative stress modulates PPAR gamma in vascular endothelial cells.

Dean P. Jones, B. Kang, J. Ritzenthaler, 2010, Free radical biology & medicine.

Attenuation of oxidant-mediated endothelial cell injury with docosahexaenoic acid: the role of intracellular iron.

C. Hart, M. D. Ober, 1998, Prostaglandins, leukotrienes, and essential fatty acids.

Smooth Muscle-Targeted Overexpression of Peroxisome Proliferator Activated Receptor-γ Disrupts Vascular Wall Structure and Function

T. Murphy, C. Hart, R. Gleason, 2015, PloS one.

Smooth Muscle-Targeted Overexpression of Peroxisome Proliferator Activated Receptor-γ Disrupts Vascular Wall Structure and Function

T. Murphy, C. Hart, R. Gleason, 2015, PloS one.

PPAR&ggr; Regulates Mitochondrial Structure and Function and Human Pulmonary Artery Smooth Muscle Cell Proliferation

B. Kang, T. Murphy, Gloria Torres, 2017, American journal of respiratory cell and molecular biology.

PPAR gamma Regulates Mitochondrial Structure and Function and Human Pulmonary Artery Smooth Muscle Cell Proliferation

B. Kang, T. Murphy, Gloria Torres, 2022 .

Endothelial Cell Peroxisome Proliferator–Activated Receptor γ Reduces Endotoxemic Pulmonary Inflammation and Injury

C. Hart, Raju C Reddy, R. Sutliff, 2012, The Journal of Immunology.

The Role of PPARγ in Pulmonary Vascular Disease

C. Hart, 2008, Journal of Investigative Medicine.

Extracellular Superoxide Dismutase Regulates Early Vascular Hyaluronan Remodeling in Hypoxic Pulmonary Hypertension

R. Midura, E. Nozik-Grayck, I. Petrache, 2020, Scientific Reports.

Hypoxia Mediates Mutual Repression between microRNA-27a and PPARγ in the Pulmonary Vasculature

B. Kang, C. Hart, J. West, 2013, PloS one.

Ethanol Induces Oxidative Stress in Alveolar Macrophages via Upregulation of NADPH Oxidases

C. Hart, L. Brown, F. Harris, 2012, The Journal of Immunology.

Chronic ethanol ingestion increases superoxide production and NADPH oxidase expression in the lung.

R. Clempus, C. Hart, D. Campbell, 2006, American journal of respiratory cell and molecular biology.

Glutathione attenuates ethanol-induced alveolar macrophage oxidative stress and dysfunction by downregulating NADPH oxidases.

C. Hart, L. Brown, F. Harris, 2014, American journal of physiology. Lung cellular and molecular physiology.

UPR modulation of host immunity by Pseudomonas aeruginosa in cystic fibrosis

J. Goldberg, A. Stecenko, C. Hart, 2021 .

Mechanisms of ionomycin-induced endothelial cell barrier dysfunction.

A. Verin, C. Hart, J. Garcia, 1997, The American journal of physiology.

Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms.

C. Hart, H. L. Rupnow, John A. Polikandriotis, 2005, Arteriosclerosis, thrombosis, and vascular biology.

Oleic acid reduces oxidant stress in cultured pulmonary artery endothelial cells.

C. Hart, M. Gupta, V. Evanoff, 1997, Experimental lung research.

The Effect of PGC-1alpha-SIRT3 Pathway Activation on Pseudomonas aeruginosa Infection

K. Bailey, J. Goldberg, C. Hart, 2022, Pathogens.

Peroxisome proliferator‐activated receptor‐γ agonists attenuate biofilm formation by Pseudomonas aeruginosa

J. Goldberg, Michael Koval, C. Hart, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Peroxisome proliferator-activated receptor- g agonists attenuate biofilm formation by Pseudomonas aeruginosa

J. Goldberg, Michael Koval, C. Hart, 2017 .

Peroxynitrite causes endothelial cell monolayer barrier dysfunction.

C. Hart, M. Gupta, F. Pavalko, 2001, American journal of physiology. Cell physiology.

special communications Peroxynitrite causes endothelial cell monolayer barrier dysfunction

Michael D. Ober, C. Hart, Mahesh P. Gupta, 2001 .

Hypoxia inhibits expression and function of mitochondrial thioredoxin 2 to promote pulmonary hypertension.

B. Kang, Y. Go, C. Hart, 2017, American journal of physiology. Lung cellular and molecular physiology.

Chronic ethanol ingestion increases aortic endothelial nitric oxide synthase expression and nitric oxide production in the rat.

S. Dikalov, C. Hart, D. Guidot, 2007, Alcoholism, clinical and experimental research.

PPARγ/ETV2 Axis Regulates Endothelial-to-Mesenchymal Transition in Pulmonary Hypertension

W. Lam, R. Benza, B. Kang, 2022, bioRxiv.

The Nox4 inhibitor GKT137831 attenuates hypoxia-induced pulmonary vascular cell proliferation.

B. Kang, T. Murphy, C. Hart, 2012, American journal of respiratory cell and molecular biology.

Identifying New Targets for Treatment of Pulmonary Hypertension.

C. Hart, A. Trammell, 2021, Chest.

OxidasesMacrophages via Upregulation of NADPH Ethanol Induces Oxidative Stress in Alveolar

C. Hart, L. Brown, F. Harris, 2012 .

Angiotensin II mediates glutathione depletion, transforming growth factor-beta1 expression, and epithelial barrier dysfunction in the alcoholic rat lung.

C. Hart, R. Bechara, L. Brown, 2005, American journal of physiology. Lung cellular and molecular physiology.

Peroxisome proliferator-activated receptor gamma (PPARγ) regulates thrombospondin-1 and Nox4 expression in hypoxia-induced human pulmonary artery smooth muscle cell proliferation

B. Kang, T. Murphy, C. Hart, 2012, Pulmonary circulation.

Supplemental fatty acids alter lipid peroxidation and oxidant injury in endothelial cells.

E. Block, C. Hart, J. Tolson, 1991, The American journal of physiology.

Proline-Rich Tyrosine Kinase 2 Downregulates Peroxisome Proliferator–Activated Receptor Gamma to Promote Hypoxia-Induced Pulmonary Artery Smooth Muscle Cell Proliferation

B. Kang, C. Hart, R. Sutliff, 2016, Pulmonary circulation.

PPARγ depletion stimulates Nox4 expression and human pulmonary artery smooth muscle cell proliferation

B. Kang, T. Murphy, C. Hart, 2015 .

Chronic ethanol ingestion increases nitric oxide production in the lung.

C. Hart, L. Brown, H. L. Rupnow, 2007, Alcohol.

Pulmonary Inflammation and Injury Reduces Endotoxemic g Activated Receptor - Endothelial Cell Peroxisome Proliferator

C. Hart, Raju C Reddy, R. Sutliff, 2012 .

Role of SGK1 in nitric oxide inhibition of ENaC in Na+-transporting epithelia.

D. Eaton, C. Hart, Ling Yu, 2005, American journal of physiology. Cell physiology.

Peroxisome proliferator-activated receptor gamma depletion stimulates Nox4 expression and human pulmonary artery smooth muscle cell proliferation.

B. Kang, T. Murphy, C. Hart, 2015, Free radical biology & medicine.

Detection of endothelial nitric oxide release with the 2,3-diaminonapthalene assay.

J. Rubin, C. Hart, D. Kleinhenz, 2003, Free radical biology & medicine.

Pharmacological reversal of post-transcriptional alterations implicated in alcohol-induced alveolar macrophage dysfunction

C. Hart, L. Brown, F. Harris, 2022, Alcohol.

The measurement of nitric oxide production by cultured endothelial cells.

S. Dikalov, C. Hart, S. Dudley, 2005, Methods in enzymology.

PPARγ

J. Roman, P. Sime, C. Hart, 2008, Journal of Investigative Medicine.

PEROXISOME PROLIFERATOR-ACTIVATED RECEPTORS

S. Han, C. Hart, J. Roman-Rodriguez, 2006 .

Hypoxia-Induced Alterations In MicroRNA-21 And -17-92 In Pulmonary Vascular Cells: Regulation By PPARg

B. Kang, C. Hart, D. Green, 2012, ATS 2012.

Quantitative fatty acid analyses in cultured porcine pulmonary artery endothelial cells: The combined effects of fatty acid supplementation and oxidant exposure

E. Block, C. Hart, J. Tolson, 1992, Journal of cellular physiology.

Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration.

Dean P. Jones, S. Dikalov, C. Hart, 2008, American journal of physiology. Heart and circulatory physiology.

PPARγ Ligands Attenuate Hypoxia-Induced Proliferation in Human Pulmonary Artery Smooth Muscle Cells through Modulation of MicroRNA-21

B. Kang, T. Murphy, C. Hart, 2015, PloS one.

Nitric oxide attenuates H(2)O(2)-induced endothelial barrier dysfunction: mechanisms of protection.

V. Natarajan, M. al-Hassani, C. Hart, 2001, American journal of physiology. Lung cellular and molecular physiology.

Fatty acid supplementation protects pulmonary artery endothelial cells from oxidant injury.

E. Block, C. Hart, J. Tolson, 1990, American journal of respiratory cell and molecular biology.

Circadian Clock Control of Nox4 and Reactive Oxygen Species in the Vasculature

R. D. Rudic, D. Fulton, D. Stepp, 2013, PloS one.

The Role of Peroxisome Proliferator-Activated Receptors in Pulmonary Vascular Disease

J. Roman, C. Hart, R. Sutliff, 2007, PPAR research.

Influence of Body Weight and Diabetes Mellitus in Patients With Pulmonary Hypertension.

Amit J. Shah, L. Phillips, C. Hart, 2020, The American journal of cardiology.

The role of NADPH oxidase in chronic intermittent hypoxia-induced pulmonary hypertension in mice.

C. Hart, D. Kleinhenz, H. L. Rupnow, 2009, American journal of respiratory cell and molecular biology.

Hypoxia-induced alterations in the lung ubiquitin proteasome system during pulmonary hypertension pathogenesis

Jing Ma, C. Hart, Jingru Zhao, 2018, Pulmonary circulation.

Rosiglitazone attenuates NF-κB-mediated Nox4 upregulation in hyperglycemia-activated endothelial cells.

Xianghuai Lu, C. Hart, R. Sutliff, 2012, American journal of physiology. Cell physiology.

Nitric Oxide Regulates Receptor Activator of Nuclear Factor-κB Ligand and Osteoprotegerin Expression in Bone Marrow Stromal Cells

Cheryl L. Ackert-Bicknell, Janet Rubin, C. Ackert-Bicknell, 2004 .

PPARγ increases HUWE1 to attenuate NF-κB/p65 and sickle cell disease with pulmonary hypertension.

R. Benza, B. Kang, C. Hart, 2021, Blood advances.

MicroRNA-98 reduces nerve growth factor expression in nicotine-induced airway remodeling

B. Kang, T. Nyunoya, C. Hart, 2020, The Journal of Biological Chemistry.

Peroxisome Proliferator-Activated Receptor γ Ligands Stimulate Endothelial Nitric Oxide Production Through Distinct Peroxisome Proliferator-Activated Receptor γ–Dependent Mechanisms

C. Hart, H. L. Rupnow, John A. Polikandriotis, 2005 .

Enhanced Clearance of Pseudomonas aeruginosa by Peroxisome Proliferator-Activated Receptor Gamma

J. Goldberg, J. Arbiser, C. Hart, 2016, Infection and Immunity.

Nitric oxide regulates receptor activator of nuclear factor-kappaB ligand and osteoprotegerin expression in bone marrow stromal cells.

C. Ackert-Bicknell, J. Rubin, T. Murphy, 2004, Endocrinology.

Peroxisome Proliferator-Activated Receptor γ Regulates Chronic Alcohol-Induced Alveolar Macrophage Dysfunction.

C. Hart, L. Brown, M. Hart, 2016, American journal of respiratory cell and molecular biology.

Extracellular Superoxide Dismutase Regulates Early Vascular Hyaluronan Remodeling in Hypoxic Pulmonary Hypertension

R. Midura, E. Nozik-Grayck, I. Petrache, 2020, Scientific Reports.

PPAR{gamma} regulates hypoxia-induced Nox4 expression in human pulmonary artery smooth muscle cells through NF-{kappa}B.

T. Murphy, Xianghuai Lu, C. Hart, 2010, American journal of physiology. Lung cellular and molecular physiology.

Exogenous fatty acids modulate the functional and cytotoxic responses of cultured pulmonary artery endothelial cells to oxidant stress.

C. Hart, M. Gupta, R. J. Karman, 1997, The Journal of laboratory and clinical medicine.

REPRODUCIBILITY OF NONINVASIVE MARKERS OF ARTERIAL COMPLIANCE MEASURED BY APPLANATION TONOMETRY: P3.173

C. Hart, M. Murphy, 2000 .

PPARγ regulates hypoxia‐induced Nox4 expression in human pulmonary artery smooth muscle cells through NF‐κB

T. Murphy, Xianghuai Lu, C. Hart, 2010 .