M. McMillian

发表

A gene expression signature for oxidant stress/reactive metabolites in rat liver.

Mark D. Johnson, Xuejun Liu, A. Bittner, 2004, Biochemical pharmacology.

Predictive toxicogenomics approaches reveal underlying molecular mechanisms of nongenotoxic carcinogenicity

A. Bittner, P. Lord, J. Wan, 2006, Molecular carcinogenesis.

Interlaboratory evaluation of genomic signatures for predicting carcinogenicity in the rat.

M. Fielden, Y. Dragan, R. Snyder, 2008, Toxicological sciences : an official journal of the Society of Toxicology.

Toxicogenomics-based discrimination of toxic mechanism in HepG2 human hepatoma cells.

R. Dunn, S. Farr, M. Burczynski, 2000, Toxicological sciences : an official journal of the Society of Toxicology.

Gonadotropin-releasing hormone action in the pituitary: a three step mechanism.

A. Penna, P. Conn, M. McMillian, 1981, Endocrine reviews.

Inverse gene expression patterns for macrophage activating hepatotoxicants and peroxisome proliferators in rat liver.

Mark D Johnson, Michael McMillian, Mark D. Johnson, 2004, Biochemical pharmacology.

Collaborations Lay the Critical Path to Acceptance of Genomics in Drug Safety Assessment

P. Lord, M. McMillian, A. Nie, 2008 .

Evidence for calcium mediation of gonadotropin releasing hormone action in the pituitary

P. Conn, M. McMillian, D. Rogers, 1980 .

Characterization of a CNS Cell Line, CAD, in which Morphological Differentiation Is Initiated by Serum Deprivation

M. McMillian, J. K. Wang, D. Chikaraishi, 1997, The Journal of Neuroscience.

The Evolution of Gene Expression Studies in Drug Safety Assessment

P. Lord, M. McMillian, A. Nie, 2006, Toxicology mechanisms and methods.

Developmental changes in rat adrenal enkephalin precursor: peptide ratio.

M. McMillian, J. Hong, P. Hudson, 1993, Brain research. Developmental brain research.

Extracellular ATP increases free cytosolic calcium in rat parotid acinar cells. Differences from phospholipase C-linked receptor agonists.

L. Cantley, B. Talamo, S. Soltoff, 1988, The Biochemical journal.

Drug-induced oxidative stress in rat liver from a toxicogenomics perspective.

Mark D. Johnson, Xuejun Liu, A. Bittner, 2005, Toxicology and applied pharmacology.

Induction of NF‐kB‐like transcription factors in brain areas susceptible to kainate toxicity

G. Bing, K. Pennypacker, I. Pérez-Otaño, 1996, Glia.

Alterations in Cardiovascular Responsiveness and Adrenoceptor Binding during Catecholamine Infusion Hypertension in Rats

S. Schanberg, M. McMillian, M. Johnson, 1991, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

Determination of cytochrome P450 1A2 and cytochrome P450 3A4 induction in cryopreserved human hepatocytes.

Mark D. Johnson, D. Roymans, M. McMillian, 2004, Biochemical pharmacology.

Dexamethasone and forskolin synergistically increase [Met5]enkephalin accumulation in mixed brain cell cultures

K. Pennypacker, M. McMillian, J.-S. Hong, 1996, Brain Research.

Catecholamines act via a beta-adrenergic receptor to maintain fetal heart rate and survival.

M. Groelle, A. Portbury, Rashmi Chandra, 2003, American journal of physiology. Heart and circulatory physiology.

Cytochrome P450 induction in rat hepatocytes assessed by quantitative real-time reverse-transcription polymerase chain reaction and the RNA invasive cleavage assay.

R. Zivin, M. Burczynski, M. McMillian, 2001, Drug metabolism and disposition: the biological fate of chemicals.

Hepatic expression of heme oxygenase-1 and antioxidant response element-mediated genes following administration of ethinyl estradiol to rats.

P. Taggart, P. Lord, Sharmilee P. Sawant, 2006, Toxicology and applied pharmacology.

Role of ω‐Conotoxin GVIA‐Sensitive Ca2+ Entry in Angiotensin II‐Stimulated [3H]Phorbol 12, 13‐Dibutyrate Binding in Bovine Adrenal Medullary Cells

M. McMillian, R. Tuominen, P. Hudson, 1993 .

Long‐Term Activation of Protein Kinase C by Nicotine in Bovine Adrenal Chromaffin Cells

M. Stachowiak, M. McMillian, R. Tuominen, 1992, Journal of neurochemistry.

Effects of muscarinic, alpha-adrenergic, and substance P agonists and ionomycin on ion transport mechanisms in the rat parotid acinar cell. The dependence of ion transport on intracellular calcium

L. Cantley, B. Talamo, S. Soltoff, 1989, The Journal of general physiology.

The effects of the HIV-1 envelope protein gp120 on the production of nitric oxide and proinflammatory cytokines in mixed glial cell cultures.

G. Bing, B. Wilson, M. McMillian, 1996, Cellular immunology.

Ontogeny of rat hepatic adrenoceptors.

S. Schanberg, C. Kuhn, M. McMillian, 1983, The Journal of pharmacology and experimental therapeutics.

Repression of oxidative stress/reactive metabolite regulated gene expression is associated with conversion of carbamazepine into a hepatotoxicant in LPS and DSS rat models

P. Taggart, M. McMillian, A. Leone, 2014 .

Regulation of tyrosine hydroxylase in olfactory bulb cultures: selective inhibition of depolarization-induced increase by endogenous opioids

K. Pennypacker, M. McMillian, J.-S. Hong, 1994, Brain Research.

Effects of [Sar1] Angiotensin II on Proenkephalin Gene Expression and Secretion of [Met5]Enkephalin in Bovine Adrenal Medullary Chromaffin Cells

Jau-Shyong Hong, M. McMillian, E. Mar, 1992, Journal of neurochemistry.

Inhibition of lipopolysaccharide-induced nitric oxide and cytokine production by ultralow concentrations of dynorphins in mixed glia cultures.

Lei Jin, Jau-Shyong Hong, M. McMillian, 1997, The Journal of pharmacology and experimental therapeutics.

Characterization of Ca2(+)-mobilizing excitatory amino acid receptors in cultured chick cortical cells.

M. McMillian, L. G. Miller, G. A. Pritchard, 1990, European journal of pharmacology.

Protein tyrosine kinase inhibitors suppress the production of nitric oxide in mixed glia, microglia-enriched or astrocyte-enriched cultures

R. Maronpot, Jau-Shyong Hong, M. McMillian, 1996, Brain Research.

Blockade of ATP binding site of P2 purinoceptors in rat parotid acinar cells by isothiocyanate compounds.

L. Cantley, B. Talamo, S. Soltoff, 1993, Biochemical pharmacology.

Angiotensin II Receptors Are Coupled to ω‐Conotoxin‐Sensitive Calcium Influx in Bovine Adrenal Medullary Chromaffin Cells

M. McMillian, R. Tuominen, J. Hong, 1992, Journal of neurochemistry.

Two distinct cytosolic calcium responses to extracellular ATP in rat parotid acinar cells

L. Cantley, B. Talamo, S. Soltoff, 1993, British journal of pharmacology.

Extracellular ATP elevates intracellular free calcium in rat parotid acinar cells.

L. Cantley, B. Talamo, S. Soltoff, 1987, Biochemical and biophysical research communications.

Elevation of [Ca2+]i and the Activation of Ion Channels and Fluxes by Extracellular ATP and Phospholipase C‐Linked Agonists in Rat Parotid Acinar Cells

L. Cantley, B. Talamo, S. Soltoff, 1990, Annals of the New York Academy of Sciences.

ATP activates a cation-permeable pathway in rat parotid acinar cells.

B. Talamo, S. Soltoff, M. McMillian, 1992, The American journal of physiology.

Effects of extracellular ATP on ion transport systems and [Ca2+]i in rat parotid acinar cells. Comparison with the muscarinic agonist carbachol

L. Cantley, B. Talamo, S. Soltoff, 1990, The Journal of general physiology.

Coomassie Brilliant Blue G is a more potent antagonist of P2 purinergic responses than Reactive Blue 2 (Cibacron Blue 3GA) in rat parotid acinar cells.

B. Talamo, S. Soltoff, M. McMillian, 1989, Biochemical and biophysical research communications.

Mediation of norepinephrine effects on free cytosolic calcium in rat parotid acinar cells by alpha 1 adrenergic receptors.

B. Talamo, S. Soltoff, M. McMillian, 1988, Biochemical pharmacology.

Nile Red binding to HepG2 cells: an improved assay for in vitro studies of hepatosteatosis.

R. Zivin, M. Burczynski, M. McMillian, 2001, In vitro & molecular toxicology.

Rapid desensitization of substance P- but not carbachol-induced increases in inositol trisphosphate and intracellular Ca++ in rat parotid acinar cells.

B. Talamo, S. Soltoff, M. McMillian, 1987, Biochemical and biophysical research communications.

Long-term stimulation of nicotinic receptors is required to increase proenkephalin A mRNA levels and the delayed secretion of [Met5]-enkephalin in bovine adrenal medullary chromaffin cells.

H. Suh, B. Wilson, M. McMillian, 1995, The Journal of pharmacology and experimental therapeutics.

Comparison with the Muscarinic Agonist Carbachol

L. Cantley, B. Talamo, S. Soltoff, 1990 .

Parasympathetic denervation increases responses to VIP in isolated rat parotid acini

B. Talamo, M. McMillian, 1989, Peptides.

Modulatory effects of [Met5]-enkephalin on interleukin-1β secretion from microglia in mixed brain cell cultures

G. Bing, Jau-Shyong Hong, M. McMillian, 1995, Journal of Neuroimmunology.

Long-term expression of the 35,000 mol. wt fos-related antigen in rat brain after kainic acid treatment

G. Bing, K. Pennypacker, M. McMillian, 1996, Neuroscience.

Application of genomics in preclinical drug safety evaluation.

Michael McMillian, Alex Nie, P. Lord, 2006, Basic & clinical pharmacology & toxicology.

An improved resazurin-based cytotoxicity assay for hepatic cells

W. J. Powers, J. W. Gunnett, M. McMillian, 2004, Cell Biology and Toxicology.

Transcription factors in primary glial cultures: changes with neuronal interactions.

K. Pennypacker, M. McMillian, P. Hudson, 1996, Brain research. Molecular brain research.

Brain injury in a dish: a model for reactive gliosis

James P. O'Callaghan, J. O'Callaghan, K. Pennypacker, 1994, Trends in Neurosciences.

CLASS PREDICTION IN TOXICOGENOMICS

Nandini Raghavan, Dhammika Amaratunga, Alex Y Nie, 2005, Journal of biopharmaceutical statistics.

Oxidative stress/reactive metabolite gene expression signature in rat liver detects idiosyncratic hepatotoxicants.

Mark D. Johnson, P. Lord, Sharmilee P. Sawant, 2014, Toxicology and applied pharmacology.

The effects of dextromethorphan on kainic acid-induced seizures in the rat.

G. Bing, K. Pennypacker, M. McMillian, 1996, Neurotoxicology.

Apolipoprotein E and mimetic peptide initiate a calcium‐dependent signaling response in macrophages

S. Pizzo, U. K. Misra, G. Gawdi, 2001, Journal of leukocyte biology.

Pharmacological regulation of AP‐1 transcription factor DNA binding activity 1

K. Pennypacker, Jau-Shyong Hong, M. McMillian, 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Protection against glutamate toxicity through inhibition of the p44/42 mitogen-activated protein kinase pathway in neuronally differentiated P19 cells.

R. Zivin, S. Emanuel, M. McMillian, 2001, Biochemical pharmacology.

Glutamate, kainate and quisqualate enhance GABA-dependent chloride uptake in cortex

M. McMillian, L. G. Miller, A. Schatzki, 1990, Brain Research Bulletin.

A Linear Prediction Rule Based on Ensemble Classifiers for Non-Genotoxic Carcinogenicity

Nandini Raghavan, Dhammika Amaratunga, Michael McMillian, 2012 .

Inter-laboratory Evaluation of Genomic Signatures for Predicting Carcinogenicity in the Rat Predictive Safety Testing Consortium, Carcinogenicity Working Group

Jiri Aubrecht, Peter Kasper, Jeremy Gollub, 2008 .

Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.

Ling Lin, M. McDonnell, J. Lenhard, 2010, Toxicological sciences : an official journal of the Society of Toxicology.

Ontogeny of Kainate‐Induced Gene Expression in Rat Hippocampus

M. McMillian, J. Douglass, K. Pennypacker, 1994, Journal of neurochemistry.

Lack of desensitization of neurokinin A due to partial agonist property of this peptide at parotid substance P receptors

B. Talamo, M. McMillian, 1989, Brain Research.

Selective killing of cholinergic neurons by microglial activation in basal forebrain mixed neuronal/glial cultures.

G. Bing, Jau-Shyong Hong, B. Wilson, 1995, Biochemical and biophysical research communications.

Implications of prolonged expression of Fos-related antigens.

K. Pennypacker, M. McMillian, J. Hong, 1995, Trends in pharmacological sciences.

Glia-dependent neurotoxicity and neuroprotection in mesencephalic cultures

I. Pérez-Otaño, M. McMillian, D. Bronstein, 1995, Brain Research.

Constitutive expression of AP-1 transcription factors in the rat adrenal. Effects of nicotine.

K. Pennypacker, M. McMillian, J. Douglass, 1992, The Journal of biological chemistry.

Dopamine Stimulates [3H]Phorbol 12,13‐Dibutyrate Binding in Cultured Striatal Cells

M. McMillian, K. Pennypacker, X. -. He, 1992, Journal of neurochemistry.

Basal expression of 35 kDa fos-related antigen in olfactory bulb.

K. Pennypacker, M. McMillian, D. Lennard, 1995, Brain research. Molecular brain research.

Elevated basal AP-1 DNA binding activity in developing rat brain.

K. Pennypacker, M. McMillian, J. Hong, 1993, Brain research. Molecular brain research.

Preferential activation of [3H]phorbol-12,13-dibutyrate binding by AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid) in neonatal striatal cell cultures

K. Pennypacker, M. McMillian, J. Hong, 1992, Brain Research.

Long‐Term Activation of Protein Kinase C by Angiotensin II in Cultured Bovine Adrenal Medullary Cells

M. Stachowiak, M. McMillian, R. Tuominen, 1991, Journal of neurochemistry.

Endogenous apolipoprotein E suppresses LPS‐stimulated microglial nitric oxide production

D. Laskowitz, E. Bennett, M. McMillian, 1998, Neuroreport.

Long-Term Expression of Proenkephalin and Prodynorphin in the Rat Brain after Systemic Administration of Kainic Acid — an in Situ Hybridization Study

G. Bing, Jau-Shyong Hong, B. Wilson, 1996 .

Acute repeated nicotine injections increase enkephalin and decrease AP-1 DNA binding activity in rat adrenal medulla.

K. Pennypacker, M. McMillian, P. Hudson, 1995, Brain Research. Molecular Brain Research.

On Methods for Gene Function Scoring as a Means of Facilitating the Interpretation of Microarray Results

Nandini Raghavan, Dhammika Amaratunga, Javier Cabrera, 2006, J. Comput. Biol..

ABC gene-ranking for prediction of drug-induced cholestasis in rats

N. Raghavan, D. Amaratunga, M. McMillian, 2016, Toxicology reports.

Release of (and lessons learned from mining) a pioneering large toxicogenomics database.

Dhammika Amaratunga, Komal S Sandhu, Vamsi Veeramachaneni, 2015, Pharmacogenomics.

Role of Protein Kinase C in Microglia‐induced Neurotoxicity in Mesencephalic Cultures

M. McMillian, P. Vainio, R. Tuominen, 1997, Journal of neuropathology and experimental neurology.

Evaluation of felbamate and other antiepileptic drug toxicity potential based on hepatic protein covalent binding and gene expression.

Mark D. Johnson, P. Lord, M. McMillian, 2007, Chemical research in toxicology.