I. Budunova

发表

Cell culture assays for chemicals with tumor-promoting or tumor-inhibiting activity based on the modulation of intercellular communication

G. Williams, I. Budunova, Irina Budunova, 1994, Cell Biology and Toxicology.

Connexin expression in epidermal cell lines from SENCAR mouse skin tumors

T. Slaga, S. Carbajal, I. Budunova, 1996, Molecular carcinogenesis.

Overexpression of connexin26 in the basal keratinocytes reduces sensitivity to tumor promoter TPA

I. Budunova, Xiao Wang, A. Ramirez, 2009, Experimental dermatology.

Androgen Receptor Drives Cellular Senescence

O. Volpert, I. Budunova, Y. Mirochnik, 2012, PloS one.

Sexual dimorphism in atrophic effects of topical glucocorticoids is driven by differential regulation of atrophogene REDD1 in male and female skin

J. Dudley, S. Agarwal, B. Readhead, 2020, Oncotarget.

Functional roles of Akt signaling in mouse skin tumorigenesis

T. Slaga, F. Larcher, J. Jorcano, 2002, Oncogene.

Roles Played by Stress-Induced Pathways in Driving Ethnic Heterogeneity for Inflammatory Skin Diseases

Matthew T. Patrick, L. Tsoi, J. Gudjonsson, 2022, Frontiers in Immunology.

Rapamycin Modulates Glucocorticoid Receptor Function, Blocks Atrophogene REDD1, and Protects Skin from Steroid Atrophy.

J. Dudley, S. Agarwal, L. Platanias, 2018, The Journal of investigative dermatology.

REDD1 functions at the crossroads between the therapeutic and adverse effects of topical glucocorticoids

J. Dudley, R. Lavker, Kit-San Yuen, 2014, EMBO molecular medicine.

Increased expression of p50-NF-kappaB and constitutive activation of NF-kappaB transcription factors during mouse skin carcinogenesis.

T. Slaga, J. Jorcano, I. Budunova, 1999, Oncogene.

Increased expression of p50-NF-κB and constitutive activation of NF-κB transcription factors during mouse skin carcinogenesis

T. Slaga, J. Jorcano, I. Budunova, 1999, Oncogene.

The tumor suppressor effect of the glucocorticoid receptor in skin is mediated via its effect on follicular epithelial stem cells

R. Lavker, I. Budunova, L. Zhu, 2007, Oncogene.

Effect of diverse tumor promoters on the expression of gap‐junctional proteins connexin (Cx) 26, Cx31.1, and Cx43 in SENCAR mouse epidermis

T. Slaga, S. Carbajal, I. Budunova, 1996, Molecular carcinogenesis.

Anti-Proliferative Effects of Compound A and Its Effect in Combination with Cisplatin in Cholangiocarcinoma Cells

G. Haegeman, P. Yenchitsomanus, I. Budunova, 2020, Asian Pacific journal of cancer prevention : APJCP.

Transcriptomic network interactions in the human skin treated with topical glucocorticoid clobetasol propionate.

J. Dudley, B. Readhead, A. Klopot, 2019, The Journal of investigative dermatology.

Targeting transcription factor NFκB: comparative analysis of proteasome and IKK inhibitors

Alexander A. Shishkin, O. Guryanova, I. Budunova, 2009, Cell cycle.

Effect of tumor promoting stimuli on gap junction permeability and connexin 43 expression in ARL 18 rat liver cell line

Gary M Williams, D. Spray, I. Budunova, 1993, Archives of Toxicology.

Altered glucocorticoid receptor expression and function during mouse skin carcinogenesis

T. Slaga, S. Carbajal, I. Budunova, 1997, Molecular carcinogenesis.

The mouse skin carcinogenesis model.

T. Slaga, I. Gimenez-Conti, I. Budunova, 1996, The journal of investigative dermatology. Symposium proceedings.

The carcinogen benzo(e)pyrene is metabolized by DM15 cells without an uncoupling effect on their gap junctions

S. Fuchs, G. Belitsky, I. Budunova, 1993, Cell Biology and Toxicology.

REDD1 (regulated in development and DNA damage 1) prevents dermal adipocyte differentiation and is required for hair cycle-dependent dermal adipose expansion.

A. Klopot, G. Baida, I. Budunova, 2020, The Journal of investigative dermatology.

N-bromotaurine surrogates for loss of antiproliferative response and enhances cisplatin efficacy in cancer cells with impaired glucocorticoid receptor.

V. Zoumpourlis, V. Gorgoulis, S. Vlahopoulos, 2016, Translational research : the journal of laboratory and clinical medicine.

Nutritional Sensor REDD1 in Cancer and Inflammation: Friend or Foe?

K. Kirsanov, E. Lesovaya, G. Belitsky, 2022, International journal of molecular sciences.

Combination of a selective activator of the glucocorticoid receptor Compound A with a proteasome inhibitor as a novel strategy for chemotherapy of hematologic malignancies

L. Gordon, S. Rosen, K. Kirsanov, 2013, Cell cycle.

Antitumor effect of non-steroid glucocorticoid receptor ligand CpdA on leukemia cell lines CEM and K562

K. Kirsanov, E. Lesovaya, M. Yakubovskaya, 2011, Biochemistry (Moscow).

Important role of kallikrein 6 for the development of keratinocyte proliferative resistance to topical glucocorticoids

J. Dudley, R. Lavker, G. Baida, 2016, Oncotarget.

PI3K inhibitors protect against glucocorticoid-induced skin atrophy

J. Dudley, S. Agarwal, B. Readhead, 2019, EBioMedicine.

Discovery of Compound A – a selective activator of the glucocorticoid receptor with anti-inflammatory and anti-cancer activity

G. Haegeman, P. Swart, A. Swart, 2015, Oncotarget.

Transcriptome analysis reveals intrinsic pro-inflammatory signaling in healthy African American skin.

A. Kel, L. Tsoi, A. Klopot, 2021, The Journal of investigative dermatology.

Disruption of eyelid and cornea development by targeted overexpression of the glucocorticoid receptor.

T. Slaga, J. Jorcano, A. Page, 2003, The International journal of developmental biology.

Abstract 3929: Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells: A novel therapeutic modality

Ximing J. Yang, I. Budunova, A. Ugolkov, 2012 .

Differential targeting of androgen and glucocorticoid receptors induces ER stress and apoptosis in prostate cancer cells

Ximing J. Yang, A. Karseladze, I. Budunova, 2012, Cell cycle.

Novel steroid receptor phyto-modulator compound a inhibits growth and survival of prostate cancer cells.

R. Chatterton, I. Budunova, S. Joshi, 2008, Cancer research.

Asymmetric expression of connexins between luminal epithelial- and myoepithelial- cells is essential for contractile function of the mammary gland.

M. Bissell, J. Inman, J. Mott, 2015, Developmental biology.

Selective Activator of the Glucocorticoid Receptor Compound A Dissociates Therapeutic and Atrophogenic Effects of Glucocorticoid Receptor Signaling in Skin

G. Haegeman, A. Klopot, G. Baida, 2015, Journal of cancer prevention.

Epithelial cells in the hair follicle bulge do not contribute to epidermal regeneration after glucocorticoid-induced cutaneous atrophy.

R. Lavker, I. Budunova, A. Yemelyanov, 2007, The Journal of investigative dermatology.

Increased telomerase activity in mouse skin premalignant progression.

T. Slaga, A. Bednarek, I. Budunova, 1995, Cancer research.

Constitutive Activation of NF-kappaB in Prostate Carcinoma Cells Through a Positive Feedback Loop: Implication of Inducible IKK-Related Kinase (IKKi)

I. Budunova, 2006 .

Regulated in Development and DNA Damage Responses 1 Prevents Dermal Adipocyte Differentiation and Is Required for Hair Cycle e Dependent Dermal Adipose Expansion

A. Klopot, G. Baida, I. Budunova, 2020 .

Androgen receptor targets NFκB and TSP1 to suppress prostate tumor growth in vivo

Emelyn H. Shroff, O. Volpert, Zhou Wang, 2007, International journal of cancer.

Early Stress-Response Gene REDD1 Controls Oxazolone-Induced Allergic Contact Dermatitis

S. Mirzoeva, A. Klopot, I. Budunova, 2021, The Journal of Immunology.

Analysis of two inbred strains of mice derived from the SENCAR stock with different susceptibility to skin tumor progression.

T. Slaga, M. Stern, C. Conti, 1998, Carcinogenesis.

Award Number: DAMD17-03-1-0522 TITLE: Constitutive Activation of NF-Κb in Prostate Carcinoma Cells through a Positive Feedback Loop: Implication of Inducible IKK-Related Kinase (Ikki)

I. Budunova, 2005 .

Skin carcinogenesis: characteristics, mechanisms, and prevention.

T. Slaga, J. DiGiovanni, I. Budunova, 1995, Progress in clinical and biological research.

The long winding road to the safer glucocorticoid receptor (GR) targeting therapies

K. Kirsanov, E. Lesovaya, M. Yakubovskaya, 2022, Oncotarget.

The expression of gap junctional proteins during different stages of mouse skin carcinogenesis.

T. Slaga, S. Carbajal, I. Budunova, 1995, Carcinogenesis.

DNA repair synthesis in N-methyl-N'-nitroso-quanidine-treated human and mouse liver cell cultures

G. Belitsky, I. Budunova, 1980 .

Effects of IKK inhibitor PS1145 on NF-kappaB function, proliferation, apoptosis and invasion activity in prostate carcinoma cells.

L. Dang, A. Karseladze, I. Budunova, 2006, Oncogene.

The role of IKK in constitutive activation of NF-kappaB transcription factor in prostate carcinoma cells.

T. Slaga, A. Karseladze, I. Budunova, 2002, Journal of cell science.

Tumor suppressor activity of glucocorticoid receptor in the prostate

Ximing J. Yang, A. Karseladze, I. Budunova, 2007, Oncogene.

Endogenous Glucocorticoid Deficiency in Psoriasis Promotes Inflammation and Abnormal Differentiation.

James T. Elder, J. Voorhees, L. Tsoi, 2017, The Journal of investigative dermatology.

Selenium compounds inhibit IκB kinase (IKK) and nuclear factor-κB (NF-κB) in prostate cancer cells

T. Slaga, I. Budunova, L. Lyakh, 2002 .

Selenium compounds inhibit I kappa B kinase (IKK) and nuclear factor-kappa B (NF-kappa B) in prostate cancer cells.

T. Slaga, J. Lü, I. Budunova, 2002, Molecular cancer therapeutics.

Role of IKKs and Transcription Factor NF-kB in Prostate Tumorigenesis

I. Budunova, 2006 .

Deletion of the glucocorticoid receptor chaperone FKBP51 prevents glucocorticoid-induced skin atrophy

J. Dudley, W. Shou, B. Readhead, 2018, Oncotarget.

The mechanisms of tumor suppressor effect of glucocorticoid receptor in skin

I. Budunova, A. Yemelyanov, D. Chebotaev, 2007, Molecular carcinogenesis.

A Novel Approach to Safer Glucocorticoid Receptor–Targeted Anti-lymphoma Therapy via REDD1 (Regulated in Development and DNA Damage 1) Inhibition

L. Gordon, J. Dudley, O. Morozova, 2020, Molecular Cancer Therapeutics.

Altered skin development and impaired proliferative and inflammatory responses in transgenic mice overexpressing the glucocorticoid receptor

T. Slaga, J. Jorcano, A. Page, 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

850 Potential role of skin in SARS-CoV-2 infection

L. Tsoi, B. Shi, A. Klopot, 2022, Journal of Investigative Dermatology.

An upward shift of intracellular pH rather than the final absolute pH value is critical for controlling gap junction permeability in tumor promoter‐treated cells

L. Mittelman, I. Budunova, L. Margolis, 1991, FEBS letters.

Resistance of transformed mouse keratinocytes to growth inhibition by glucocorticoids

T. Slaga, S. Carbajal, I. Budunova, 1997, Molecular carcinogenesis.

Changes in protein expression during multistage mouse skin carcinogenesis

T. Slaga, M. Stern, C. Conti, 1997, Molecular carcinogenesis.

Glucocorticoid receptor functions as a potent suppressor of mouse skin carcinogenesis

T. Slaga, J. Jorcano, I. Budunova, 2003, Oncogene.

Changes in protein expression during multistage mouse skin carcinogenesis

T. Slaga, M. Stern, J. Rundhaug, 1997, Molecular carcinogenesis.

Transcriptome analysis reveals intrinsic pro-inflammatory signaling in healthy African American skin.

A. Kel, L. Tsoi, A. Klopot, 2021, The Journal of investigative dermatology.

REDD1 (regulated in development and DNA damage 1) prevents dermal adipocyte differentiation and is required for hair cycle-dependent dermal adipose expansion

A. Klopot, G. Baida, I. Budunova, 2020 .

Effect of benzo(a)pyrene on monolayer cultures of normal and malignant mouse liver cells

I. Budunova, R. M. Vainberg, 1977, Bulletin of Experimental Biology and Medicine.