M. Schaap

发表

Finding transcriptomics biomarkers for in vivo identification of (non-)genotoxic carcinogens using wild-type and Xpa/p53 mutant mouse models.

T. Breit, M. van Iterson, M. Jonker, 2009, Carcinogenesis.

Delayed expression of apoptotic and cell-cycle control genes in carcinogen-exposed bladders of mice lacking p53.S389 phosphorylation.

J. Pennings, T. Breit, M. Jonker, 2007, Carcinogenesis.

Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models

A. Boorsma, H. Loveren, M. Luijten, 2014, Archives of Toxicology.

Detection of genotoxic and non-genotoxic carcinogens in Xpc(-/-)p53(+/-) mice.

A. Verhoef, R. Kuiper, H. van Steeg, 2013, Toxicology and applied pharmacology.

Proliferating primary hepatocytes from the pUR288 lacZ plasmid mouse are valuable tools for genotoxicity assessment in vitro

P. White, E. Zwart, H. Steeg, 2012, Environmental and molecular mutagenesis.

The insulin receptor substrate‐1 Gly972Arg polymorphism is not associated with Type 2 diabetes mellitus in two population‐based studies

E. Feskens, R. V. van Dam, J. Seidell, 2004, Diabetic medicine : a journal of the British Diabetic Association.

Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: Toxicokinetics is essential for in vivo–in vitro comparisons

J. Kleinjans, R. Godschalk, H. van Steeg, 2012, Archives of Toxicology.

Common variants in the ATP‐sensitive K+ channel genes KCNJ11 (Kir6.2) and ABCC8 (SUR1) in relation to glucose intolerance: population‐based studies and meta‐analyses 1

E. Feskens, R. V. van Dam, J. Seidell, 2005, Diabetic medicine : a journal of the British Diabetic Association.

Adipose gene expression patterns of weight gain suggest counteracting steroid hormone synthesis.

J. Pennings, J. Keijer, E. V. van Schothorst, 2005, Obesity research.

Detection of the mechanism of immunotoxicity of cyclosporine A in murine in vitro and in vivo models

A. Boorsma, H. Loveren, M. Luijten, 2014, Archives of Toxicology.

Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes

T. Breit, B. van de Water, M. Jonker, 2012, Archives of Toxicology.

Overlapping gene expression profiles of model compounds provide opportunities for immunotoxicity screening.

Martijs J Jonker, Jeroen L A Pennings, Timo M Breit, 2008, Toxicology and applied pharmacology.

Toxicogenomics directory of chemically exposed human hepatocytes

R. Stierum, G. Myatt, J. Rahnenführer, 2014, Archives of Toxicology.

In vivo murine hepatic microRNA and mRNA expression signatures predicting the (non-)genotoxic carcinogenic potential of chemicals

T. Breit, W. Ijcken, M. Jonker, 2014, Archives of Toxicology.

Dissecting modes of action of non-genotoxic carcinogens in primary mouse hepatocytes

T. Breit, M. Jonker, E. Zwart, 2012, Archives of Toxicology.

Mice expressing a mammary gland-specific R270H mutation in the p53 tumor suppressor gene mimic human breast cancer development.

T. Jacks, D. Tuveson, J. Jonkers, 2005, Cancer research.

Dominant-negative but not gain-of-function effects of a p53.R270H mutation in mouse epithelium tissue after DNA damage.

T. Jacks, J. Jonkers, L. Attardi, 2007, Cancer research.

Benzo[a]pyrene-induced transcriptomic responses in primary hepatocytes and in vivo liver: Toxicokinetics is essential for in vivo–in vitro comparisons

J. Kleinjans, R. Godschalk, H. Steeg, 2012, Archives of Toxicology.

transcription-coupled repair status in the mouse lung independently of the Ozone induces clear cellular and molecular responses

J. Pennings, I. Kooter, T. Breit, 2015 .

Ozone induces clear cellular and molecular responses in the mouse lung independently of the transcription-coupled repair status.

J. Pennings, I. Kooter, T. Breit, 2007, Journal of applied physiology.

Dual-Use Quickscan: A Web-Based Tool to Assess the Dual-Use Potential of Life Science Research

S. Rutjes, M. Schaap, M. V. van Passel, 2021, Frontiers in Bioengineering and Biotechnology.

A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens

T. Breit, M. Jonker, E. Zwart, 2015, Archives of Toxicology.

lacZ mouse embryonic fibroblasts detect both clastogens and mutagens.

E. Zwart, H. van Steeg, A. de Vries, 2009, Mutation research.

DNA-repair-deficient Rad54/Rad54B mice are more sensitive to clastogens than wild-type mice.

H. van Steeg, A. de Vries, J. van Benthem, 2008, Toxicology letters.

Comparison of clastogen-induced gene expression profiles in wild-type and DNA repair-deficient Rad54/Rad54B cells

J. Pennings, H. van Steeg, J. van Benthem, 2010, BMC Genomics.

Toxicogenomics directory of chemically exposed human hepatocytes

R. Stierum, G. Myatt, J. Rahnenführer, 2014, Archives of Toxicology.

A novel toxicogenomics-based approach to categorize (non-)genotoxic carcinogens

T. Breit, M. Jonker, E. Zwart, 2014, Archives of Toxicology.