P. Moulin

发表

Identification of Dlk1-Dio3 imprinted gene cluster noncoding RNAs as novel candidate biomarkers for liver tumor promotion.

A. Zell, P. Couttet, D. Schübeler, 2013, Toxicological sciences : an official journal of the Society of Toxicology.

Assessment of diffusion‐weighted MR imaging in liver fibrosis

B. V. Van Beers, I. Leclercq, F. Peeters, 2007, Journal of magnetic resonance imaging : JMRI.

Extensive Profiling of the Expression of the Indoleamine 2,3-Dioxygenase 1 Protein in Normal and Tumoral Human Tissues

J. Renauld, C. Sempoux, E. Marbaix, 2014, Cancer Immunology Research.

Aristolochic acid nephropathy and the peritoneum: Functional, structural, and molecular studies.

V. Arlt, D. Phillips, O. Devuyst, 2003, Kidney international.

Transitional cell carcinoma involving the prostate: a clinicopathological retrospective study of 76 cases.

J. Jamart, P. Moulin, P. V. Van Cangh, 2003, The Journal of urology.

The PPARgamma agonist pioglitazone inhibits early neoplastic occurrence in the rat liver.

C. Sempoux, I. Leclercq, I. Borbath, 2007, European journal of cancer.

mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

M. Hall, M. Boerries, H. Busch, 2014, Proceedings of the National Academy of Sciences.

Human Endometrial Epithelial Cells (EEC) Constitutively Express More Intercellular Adhesion Molecule (ICAM)‐1 than Endometrial Stromal Cells (ESC) in Culture

P. Moulin, J. Donnez, A. van Langendonckt, 2005, American journal of reproductive immunology.

Expression of Intercellular Adhesion Molecule-1 and Vascular Cell Adhesion Molecule-1 in Human Endometrial Stromal and Epithelial Cells Is Regulated by Interferon-Gamma but Not Iron

P. Moulin, J. Donnez, A. van Langendonckt, 2007, Gynecologic and Obstetric Investigation.

Menstrual breakdown of human endometrium can be mimicked in vitro and is selectively and reversibly blocked by inhibitors of matrix metalloproteinases.

P. Courtoy, E. Marbaix, P. Moulin, 1996, Proceedings of the National Academy of Sciences of the United States of America.

Controlled Mycobacterium tuberculosis infection in mice under treatment with anti-IL-17A or IL-17F antibodies, in contrast to TNFα neutralization

B. Ryffel, M. Le Bert, F. D. Di Padova, 2016, Scientific Reports.

Human Type 2 Diabetes Morphological Evidence for Abnormal-Cell Function

C. Sempoux, D. Dubois, Y. Guiot, 2001 .

Impact of Sur1 gene inactivation on the morphology of mouse pancreatic endocrine tissue

C. Sempoux, Y. Guiot, P. Moulin, 2009, Cell and Tissue Research.

Glucose-induced cytosolic pH changes in beta-cells and insulin secretion are not causally related: studies in islets lacking the Na+/H+ exchangeR NHE1.

P. Moulin, J. Henquin, J. Jonas, 2007, The Journal of biological chemistry.

Chronic uremia induces permeability changes, increased nitric oxide synthase expression, and structural modifications in the peritoneum.

O. Devuyst, T. Miyata, N. Lameire, 2001, Journal of the American Society of Nephrology : JASN.

Cardiomyocyte-Restricted Overexpression of Endothelial Nitric Oxide Synthase (NOS3) Attenuates &bgr;-Adrenergic Stimulation and Reinforces Vagal Inhibition of Cardiac Contraction

J. Balligand, O. Feron, C. Dessy, 2004, Circulation.

Human type 2 diabetes: morphological evidence for abnormal beta-cell function.

C. Sempoux, D. Dubois, Y. Guiot, 2001, Diabetes.

No decrease of the beta-cell mass in type 2 diabetic patients.

C. Sempoux, Y. Guiot, P. Moulin, 2001, Diabetes.

No decrease of the B cell mass in type 2 diabetic patients.

C. Sempoux, Y. Guiot, P. Moulin, 2000 .

Antibody blockade of IL‐17 family cytokines in immunity to acute murine oral mucosal candidiasis

S. Gaffen, F. Kolbinger, E. Traggiai, 2016, Journal of leukocyte biology.

Mice that lack endothelial nitric oxide synthase are protected against functional and structural modifications induced by acute peritonitis.

J. Balligand, O. Feron, O. Devuyst, 2003, Journal of the American Society of Nephrology : JASN.

Experimental diabetes induces functional and structural changes in the peritoneum.

O. Feron, O. Devuyst, N. Lameire, 2002, Kidney international.

Differential expression of dipeptidyl peptidase IV in human versus cynomolgus monkey skin eccrine sweat glands

Serafino Pantano, P. Couttet, O. Grenet, 2013, Journal of Molecular Histology.

Retro-orbital blood acquisition facilitates circulating microRNA measurement in zebrafish with paracetamol hepatotoxicity.

J. Dear, B. K. Park, C. Goldring, 2014, Zebrafish.

Investigation of Correlation Among Safety Biomarkers in Serum, Histopathological Examination, and Toxicogenomics

F. Pognan, M. Wiesmann, J. Markovits, 2011, International journal of toxicology.

The use of rat lens explant cultures to study the mechanism of drug-induced cataractogenesis.

F. Pognan, N. Shangari, S. Chibout, 2012, Toxicological sciences : an official journal of the Society of Toxicology.

Peripheral Sympathetic System and Neuropeptide Y Vascular Origin of Vildagliptin-induced Skin Effects in Cynomolgus Monkeys : Pathomechanistic Role of

Wei Zhou, V. Kaushik, Nick, 2014 .

Suppression of the Nrf2-Dependent Antioxidant Response by Glucocorticoids and 11β-HSD1-Mediated Glucocorticoid Activation in Hepatic Cells

A. Odermatt, D. Kratschmar, A. Lister, 2012, PloS one.

The focal form of persistent hyperinsulinemic hypoglycemia of infancy: morphological and molecular studies show structural and functional differences with insulinoma.

C. Junien, C. Sempoux, K. Dahan, 2003, Diabetes.

Cardiomyocyte-restricted overexpression of endothelial nitric oxide synthase (NOS3) potentiates postsynaptic vagal inhibition of cardiac contraction in vivo and in vitro

J. Balligand, O. Feron, C. Dessy, 2004 .

Reduced Activity of Sphingosine-1-Phosphate Lyase Induces Podocyte-related Glomerular Proteinuria, Skin Irritation, and Platelet Activation

S. Côté, F. Pognan, P. Moulin, 2015, Toxicologic pathology.

A Multicentre, Double-Blind, Placebo-Controlled, Parallel-Group Study to Evaluate the Efficacy, Safety, and Tolerability of the S1P Receptor Agonist KRP203 in Patients with Moderately Active Refractory Ulcerative Colitis

G. Rogler, G. Van Assche, P. Lakatos, 2020, Inflammatory Intestinal Diseases.

Aquaporin-1 plays an essential role in water permeability and ultrafiltration during peritoneal dialysis.

A. Verkman, J. Verbavatz, O. Devuyst, 2006, Kidney international.

Editor’s Highlight: Comparative Renal Safety Assessment of the Hepatitis B Drugs, Adefovir, Tenofovir, Telbivudine and Entecavir in Rats

F. Pognan, N. Beckmann, V. Dubost, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Urinary clusterin, cystatin C, β2-microglobulin and total protein as markers to detect drug-induced kidney injury

Serafino Pantano, F. Staedtler, O. Grenet, 2010, Nature Biotechnology.

Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.

P. Couttet, D. Theil, J. Thomson, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

Epigenomics – Impact for Drug Safety Sciences

P. Couttet, D. J. Heard, O. Grenet, 2012 .

Heart Structure-Specific Transcriptomic Atlas Reveals Conserved microRNA-mRNA Interactions

P. Couttet, E. Oakeley, Ming-Sin Cheung, 2013, PloS one.

Resistance mechanisms to TP53-MDM2 inhibition identified by in vivo piggyBac transposon mutagenesis screen in an Arf−/− mouse model

Eric Y. Durand, J. Lehár, W. Sellers, 2017, Proceedings of the National Academy of Sciences.

The Utility of Gene Expression Profiling from Tissue Samples to Support Drug Safety Assessments.

Pierre Moulin, D. Stiehl, S. Chibout, 2017, ILAR journal.

Differential expression of dipeptidyl peptidase IV in human versus cynomolgus monkey skin eccrine sweat glands

Serafino Pantano, P. Couttet, O. Grenet, 2013, Journal of Molecular Histology.

Unusual Metastatic Features in a Patient with Concomitant Malignant Orbital Melanoma and Prostate Carcinoma

J. Machiels, J. Baurain, P. Moulin, 2004, Journal of Neuro-Oncology.

Identification and subcellular localization of the Na+/H+ exchanger and a novel related protein in the endocrine pancreas and adrenal medulla.

O. Devuyst, Y. Guiot, P. Moulin, 2007, Journal of molecular endocrinology.

Natural killer cell cytokine production, not cytotoxicity, contributes to resistance against blood-stage Plasmodium chabaudi AS infection.

P. Moulin, M. Stevenson, K. Mohan, 1997, Journal of immunology.

Vascular proliferation and enhanced expression of endothelial nitric oxide synthase in human peritoneum exposed to long-term peritoneal dialysis.

O. Devuyst, T. Miyata, P. Moulin, 2000, Journal of the American Society of Nephrology : JASN.

Altered polarity and expression of H+-ATPase without ultrastructural changes in kidneys of Dent's disease patients.

P. Courtoy, P. Verroust, O. Devuyst, 2003, Kidney international.

Investigative safety science as a competitive advantage for Pharma

David J Heard, Michael Merz, Pierre Moulin, 2012, Expert opinion on drug metabolism & toxicology.

Nitric oxide synthase isoforms play distinct roles during acute peritonitis

J. Balligand, O. Devuyst, J. Ni, 2009, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.

Regulation of aquaporin-1 and nitric oxide synthase isoforms in a rat model of acute peritonitis.

J. Balligand, J. Verbavatz, O. Devuyst, 1999, Journal of the American Society of Nephrology : JASN.

35th Annual meeting of the European Association for the Study of Diabetes. Brussels, Belgium, 28 September-2 October, 1999. Abstracts.

Thomas J. Smith, B. M. Rasmussen, V. C. Phan, 1999, Diabetologia.

Longitudinal noninvasive magnetic resonance imaging of brain microhemorrhages in BACE inhibitor–treated APP transgenic mice

M. Staufenbiel, D. Theil, R. Kreutzer, 2016, Neurobiology of Aging.

Xenobiotic CAR Activators Induce Dlk1-Dio3 Locus Noncoding RNA Expression in Mouse Liver

A. Zell, H. Ellinger-Ziegelbauer, M. Schwarz, 2017, Toxicological sciences : an official journal of the Society of Toxicology.

Inhibition of early preneoplastic events in the rat liver by the somatostatin analog lanreotide

C. Sempoux, I. Leclercq, I. Borbath, 2007, Cancer science.

The Application, Challenges, and Advancement Toward Regulatory Acceptance of Digital Toxicologic Pathology: Results of the 7th ESTP International Expert Workshop (September 20-21, 2019)

Robert Klopfleisch, Pierre Moulin, Peter Hall, 2020, Toxicologic pathology.

IMI—Bigpicture: A Central Repository for Digital Pathology

P. Moulin, Erio Barale-Thomas, K. Grünberg, 2021, Toxicologic pathology.

Novel Anti-CD40 Monoclonal Antibody CFZ533 in Patients with Primary Sjogren Syndrome: A Phase Iia Double-Blind, Placebo–Controlled Randomized Trial

D. Isenberg, M. Rotte, W. Ng, 2018, Oral surgery, oral medicine, oral pathology and oral radiology.

Vascular Origin of Vildagliptin-induced Skin Effects in Cynomolgus Monkeys

Serafino Pantano, N. Flavahan, V. Kaushik, 2014, Toxicologic pathology.

Epstein-Barr virus (EBV)-induced liver failure in the absence of extensive liver-cell necrosis: a case for cytokine-induced liver dysfunction?

P. Moulin, A. Geubel, M. Jungers, 2004, Journal of hepatology.

HistoNet: A Deep Learning-Based Model of Normal Histology

Oliver C. Turner, Holger Hoefling, Chandrassegar Saravanan, 2021, Toxicologic pathology.

mTORC1 maintains renal tubular homeostasis and is essential in response to ischemic stress

M. Boerries, H. Busch, F. Artunc, 2014, Proceedings of the National Academy of Sciences.

Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.

P. Couttet, D. Theil, H. Ellinger-Ziegelbauer, 2014, Toxicological sciences : an official journal of the Society of Toxicology.

A deep learning-based model of normal histology

Pierre Moulin, Imtiaz Hossain, Tobias Sing, 2019, bioRxiv.

Outsourcing Tissue Histopathology Investigations in Support of Clinical Trials for Novel Therapeutics: Considerations and Perspectives

Benjamin H. Lee, Xiaoyu Jiang, R. Hillenbrand, 2014 .