Ashutosh Kumar

发表

Self healing hydrogels composed of amyloid nano fibrils for cell culture and stem cell differentiation.

S. Sen, Dhiman Ghosh, N. N. Jha, 2015, Biomaterials.

Broadband Excitation by Method of Double Sweep

N. Khaneja, Ashutosh Kumar, 2016, 1611.08831.

Differential copper binding to alpha-synuclein and its disease-associated mutants affect the aggregation and amyloid formation.

Dhiman Ghosh, S. Maji, Subhadeep Das, 2017, Biochimica et biophysica acta. General subjects.

Azadirachtin inhibits amyloid formation, disaggregates pre-formed fibrils and protects pancreatic β-cells from human islet amyloid polypeptide/amylin-induced cytotoxicity.

R. Chakrabarti, Ashutosh Kumar, Soham Sarkar, 2019, The Biochemical journal.

Molecular dynamics simulations elucidate the mode of protein recognition by Skp1 and the F‐box domain in the SCF complex

Ashutosh Kumar, Sarath Chandra Dantu, Nitin Nathubhai Kachariya, 2016, Proteins.

Conformational flexibility of histone variant CENP-ACse4 is regulated by histone H4: A mechanism to stabilize soluble Cse4

G. Krishnamoorthy, Ashutosh Kumar, Shivangi Shukla, 2018, The Journal of Biological Chemistry.

Structural plasticity of CENP-A regulated by H4 influences cellular levels and kinetochore assembly

G. Krishnamoorthy, Ashutosh Kumar, S. Dantu, 2018, bioRxiv.

A novel method for the chaperone aided and efficient production of human proinsulin in the prokaryotic system.

Haniyeh Najafi, Ashutosh Kumar, R. Yousefi, 2022, Journal of biotechnology.

Penetratin inhibits α-synuclein fibrillation and improves locomotor functions in mice model of Parkinson’s disease

A. Gautam, D. Otzen, G. Raghava, 2022, bioRxiv.

α-Synuclein aggregation nucleates through liquid–liquid phase separation

R. Riek, G. Krishnamoorthy, Satyaprakash Pandey, 2020, Nature Chemistry.

Perturbation in Long-Range Contacts Modulates the Kinetics of Amyloid Formation in α-Synuclein Familial Mutants.

Ashutosh Kumar, Priyatosh Ranjan, 2017, ACS chemical neuroscience.

Glycosaminoglycans have variable effects on α-synuclein aggregation and differentially affect the activities of the resulting amyloid fibrils

Dhiman Ghosh, Anoop Arunagiri, N. N. Jha, 2018, The Journal of Biological Chemistry.

Modulating α-Synuclein Liquid-Liquid Phase Separation.

R. Riek, Dhiman Ghosh, S. Maji, 2021, Biochemistry.

Amyloid formation of growth hormone in presence of zinc: Relevance to its storage in secretory granules

Saikat Ghosh, Anoop Arunagiri, N. N. Jha, 2016, Scientific Reports.

Disulfide bond regulates somatostatin-14 amyloid formation 1 Elucidating the role of disulfide bond on amyloid formation and fibril reversibility of somatostatin-14: Relevance to its storage and secretion*

Ranjith, Saikat Ghosh, Srivastav Ranganathan, 2014 .

Distinct mode of membrane interaction and disintegration by diverse class of antimicrobial peptides.

A. Maity, Ashutosh Kumar, R. Chakrabarti, 2022, Biochimica et biophysica acta. Biomembranes.

Catching Nucleosome by Its Decorated Tails Determines Its Functional States

Ashutosh Kumar, Parveen Sehrawat, Rahul Shobhawat, 2022, Frontiers in genetics.

Multi-omics analysis and systems biology integration identifies the roles of IL-9 in keratinocyte metabolic reprogramming.

Sanjeeva Srivastava, K. Venkatesh, Ashutosh Kumar, 2021, The Journal of investigative dermatology.

Comparison of Kinetics, Toxicity, Oligomer Formation, and Membrane Binding Capacity of α-Synuclein Familial Mutations at the A53 Site, Including the Newly Discovered A53V Mutation.

S. Maji, A. Navalkar, Namrata Singh, 2018, Biochemistry.

Comparison of α-Synuclein Fibril Inhibition by Four Different Amyloid Inhibitors.

Dhiman Ghosh, N. N. Jha, S. Maji, 2017, ACS chemical neuroscience.

The Parkinson's disease-associated H50Q mutation accelerates α-Synuclein aggregation in vitro.

Saikat Ghosh, Dhiman Ghosh, Anoop Arunagiri, 2013, Biochemistry.

A Protofilament-Protofilament Interface in the Structure of Mouse α-Synuclein Fibrils.

D. Eliezer, Ashutosh Kumar, Yun-Tzu Huang, 2018, Biophysical journal.

Myricetin protects pancreatic β-cells from human islet amyloid polypeptide (hIAPP) induced cytotoxicity and restores islet function

Ashutosh Kumar, Shilpy Sharma, R. Dubey, 2020, Biological chemistry.

Intrinsic disorder in CENP-ACse4 tail and its chaperone facilitates synergistic association for kinetochore stabilization

Ashutosh Kumar, Shivangi Shukla, R. Hosur, 2022, bioRxiv.

Mapping of Methyl Epitopes of a Peptide‐Drug with Its Receptor by 2D STDD‐Methyl TROSY NMR Spectroscopy

Ashutosh Kumar, N. Vajpai, Anomitra Dey, 2022, Chembiochem : a European journal of chemical biology.

Cross-correlative 3D micro-structural investigation of human bone processed into bone allografts.

A. Singh, N. Chattopadhyay, C. Singh, 2016, Materials science & engineering. C, Materials for biological applications.

Unfolding of CPR3 Gets Initiated at the Active Site and Proceeds via Two Intermediates.

Ashutosh Kumar, R. Hosur, B. Ahmad, 2017, Biophysical journal.

Alanine check points in HNN and HN(C)N spectra.

Ashutosh Kumar, R. Hosur, A. Chatterjee, 2006, Journal of magnetic resonance.

Structural properties of pore-forming oligomers of alpha-synuclein.

R. Benz, H. Lashuel, S. Becker, 2009, Journal of the American Chemical Society.

Complexation of NAC-Derived Peptide Ligands with the C-Terminus of α-Synuclein Accelerates Its Aggregation.

Dhiman Ghosh, Srivastav Ranganathan, N. N. Jha, 2017, Biochemistry.

Human islet amyloid polypeptide (hIAPP) - a curse in type II diabetes mellitus: insights from structure and toxicity studies

Ashutosh Kumar, Shilpy Sharma, A. Bishoyi, 2020, Biological chemistry.

Developing a novel exenatide-based incretin mimic (αB-Ex): Expression, purification and structural-functional characterization.

Ashutosh Kumar, R. Yousefi, A. Niazi, 2022, Biochimica et biophysica acta. General subjects.

Centromere Chromatin Dynamics at a Glance

Ashutosh Kumar, Shivangi Shukla, 2022, Epigenomes.

Disordered regions tune order in chromatin organization and function.

Ashutosh Kumar, Shivangi Shukla, P. Agarwal, 2021, Biophysical chemistry.

Structure based aggregation studies reveal the presence of helix-rich intermediate during α-Synuclein aggregation

R. Riek, S. Sen, Dhiman Ghosh, 2015, Scientific Reports.

NMR of unfolded proteins

S. Srivastava, Ashutosh Kumar, R. Hosur, 2005 .

The newly discovered Parkinson's disease associated Finnish mutation (A53E) attenuates α-synuclein aggregation and membrane binding.

Dhiman Ghosh, S. Maji, R. Banerjee, 2014, Biochemistry.

Effect of disease-associated P123H and V70M mutations on β-synuclein fibrillation.

S. Maji, A. Navalkar, Ashutosh Kumar, 2020, ACS chemical neuroscience.

Curcumin modulates α-synuclein aggregation and toxicity.

Dhiman Ghosh, S. Maji, P. Singh, 2013, ACS chemical neuroscience.

Antimicrobial peptide ROAD–1 triggers phase change in local membrane environment to execute its activity

Ashutosh Kumar, S. Vasudevan, 2019, Journal of Molecular Modeling.

Resonance assignment of disordered protein with repetitive and overlapping sequence using combinatorial approach reveals initial structural propensities and local restrictions in the denatured state

Ashutosh Kumar, Nikita Malik, 2016, Journal of Biomolecular NMR.

Pre‐fibrillar α‐synuclein variants with impaired β‐structure increase neurotoxicity in Parkinson's disease models

H. Jäckle, S. Kügler, G. Braus, 2009, The EMBO journal.

WhmD promotes the assembly of Mycobacterium smegmatis FtsZ: A possible role of WhmD in bacterial cell division.

D. Panda, Ashutosh Kumar, Dipanwita Bhattacharya, 2016, International journal of biological macromolecules.

Mutation of Arg191 in FtsZ Impairs Cytokinetic Abscission of Bacillus subtilis Cells.

D. Panda, Ashutosh Kumar, S. Yadav, 2016, Biochemistry.

Liquid-liquid phase separation and liquid-to-solid transition mediate α-synuclein amyloid fibril containing hydrogel formation

R. Riek, G. Krishnamoorthy, Satyaprakash Pandey, 2019, bioRxiv.

The Involvement of His50 during Protein Disulfide Isomerase Binding Is Essential for Inhibiting α-Syn Fibril Formation.

Ashutosh Kumar, Priyatosh Ranjan, 2016, Biochemistry.

A novel strategy for production of liraglutide precursor peptide and development of a new long-acting incretin mimic

A. Moosavi-Movahedi, Ashutosh Kumar, R. Yousefi, 2022, PloS one.

Recombinant human islet amyloid polypeptide forms shorter fibrils and mediates β-cell apoptosis via generation of oxidative stress.

Ashutosh Kumar, Shilpy Sharma, N. S. Bhavesh, 2017, The Biochemical journal.

NMR characterization of the energy landscape of SUMO-1 in the native-state ensemble.

S. Srivastava, Ashutosh Kumar, R. Hosur, 2007, Journal of molecular biology.

Residue-level NMR view of the urea-driven equilibrium folding transition of SUMO-1 (1-97): native preferences do not increase monotonously.

S. Srivastava, Ashutosh Kumar, R. Hosur, 2006, Journal of molecular biology.

Structural comparison of mouse and human α-synuclein amyloid fibrils by solid-state NMR.

S. Becker, D. Riedel, K. Giller, 2012, Journal of molecular biology.

Solid-state NMR reveals structural differences between fibrils of wild-type and disease-related A53T mutant alpha-synuclein.

S. Becker, T. Jovin, D. Riedel, 2008, Journal of molecular biology.

Benzimidazole‐based fluorophores for the detection of amyloid fibrils with higher sensitivity than Thioflavin‐T

J. Johansson, S. Maji, A. Navalkar, 2020, Journal of neurochemistry.

SUMO1 hinders α‐Synuclein fibrillation by inducing structural compaction

R. Padinhateeri, Ashutosh Kumar, Rakesh Krishnan, 2023, Protein science : a publication of the Protein Society.

Backbone and side chain assignments of human cell cycle regulatory protein S-phase kinase-associated protein 1

Ashutosh Kumar, S. Dantu, N. Kachariya, 2016, Biomolecular NMR Assignments.

Monitoring size and oligomeric-state distribution of therapeutic mAbs by NMR and DLS: Trastuzumab as a case study.

A. Rathore, Ashutosh Kumar, Srishti Joshi, 2020, Journal of pharmaceutical and biomedical analysis.

Structural Properties of Pore-Forming Oligomers of r-Synuclein

R. Benz, H. Lashuel, S. Becker, 2009 .

Backbone and side chain assignments of human cell cycle regulatory protein S-phase kinase-associated protein 1

Ashutosh Kumar, S. Dantu, N. Kachariya, 2016, Biomolecular NMR Assignments.

Elucidating the Role of Disulfide Bond on Amyloid Formation and Fibril Reversibility of Somatostatin-14

Saikat Ghosh, Srivastav Ranganathan, Anoop Arunagiri, 2014, The Journal of Biological Chemistry.

Local structural preferences and dynamics restrictions in the urea-denatured state of SUMO-1: NMR characterization.

S. Srivastava, Ashutosh Kumar, R. Hosur, 2006, Biophysical journal.

Structural insight into the mechanism of action of antimicrobial peptide BMAP-28(1-18) and its analogue mutBMAP18.

Ashutosh Kumar, S. Vasudevan, N. Agadi, 2018, Journal of structural biology.

1H, 15N, 13C resonance assignment of folded and 8 M urea-denatured state of SUMO from Drosophila melanogaster

Ashutosh Kumar, R. Hosur, Shilpy Sharma, 2008, Biomolecular NMR assignments.

Amyloid Fibrils with Positive Charge Enhance Retroviral Transduction in Mammalian Cells.

Dhiman Ghosh, S. Maji, P. Tayalia, 2018, ACS biomaterials science & engineering.

Myricetin encapsulated chitosan nanoformulation for management of type 2 diabetes: Preparation, optimization, characterization and in vivo activity.

B. Mishra, Ashutosh Kumar, R. Hosur, 2023, Biomaterials advances.

Solid-State NMR Reveals Structural Differences between Fibrils of Wild-Type and Disease-Related A 53 T Mutant α-Synuclein

S. Becker, T. Jovin, D. Riedel, 2008 .

Self healing hydrogels composed of amyloid nano fibrils for cell culture and stem cell differentiation.

S. Sen, Dhiman Ghosh, N. N. Jha, 2015, Biomaterials.

Combined Liquid-State and Solid-State Nuclear Magnetic Resonance at Natural Abundance for Comparative Higher Order Structure Assessment in the Formulated-State of Biphasic Biopharmaceutics.

Ashutosh Kumar, Rudra N Purusottam, Pramod S Mali, 2023, Analytical chemistry.