J. Maloteaux

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Impact of genomics on drug discovery and clinical medicine.

C. Caldas, G. Emilien, O. Isacson, 2000, QJM : monthly journal of the Association of Physicians.

Acute up‐regulation of glutamate uptake mediated by mGluR5a in reactive astrocytes

J. Maloteaux, Sébastien Tilleux, E. Hermans, 2005, Journal of neurochemistry.

Overexpression of the myelin basic protein RNA in the cortex of a patient with Alzheimer's disease.

J. Maloteaux, J. Octave, A. Macq, 1989, Acta neurologica Belgica.

Dopamine receptors and schizophrenia: contribution of molecular genetics and clinical neuropsychology.

M. Owen, G. Emilien, J. Maloteaux, 1999, The international journal of neuropsychopharmacology.

Involvement of the sigma1 receptor in the modulation of dopaminergic transmission by amantadine

T. Su, J. Maloteaux, E. Hermans, 2004, The European journal of neuroscience.

Is the sigma 2 receptor in rat brain related to the K+ channel of class III antiarrhythmic drugs?

J. Maloteaux, A. Jeanjean, M. Mestre, 1993, European journal of pharmacology.

Benzodiazepine receptors in human brain: Characterization, subcellular localization and solubilization

P. Kollmann, C. Laterre, J. Maloteaux, 1988, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Interleukin-1β induces long-term increase of axonally transported opiate receptors and substance P

J. Maloteaux, A. Jeanjean, P. Laduron, 1995, Neuroscience.

Cultured astrocytes derived from corpus callosum or cortical grey matter show distinct glutamate handling properties

J. Maloteaux, E. Hermans, E. Kozlova, 2009, Journal of neurochemistry.

GABA induces down-regulation of the benzodiazepine-GABA receptor complex in the rat cultured neurons.

C. Laterre, J. Maloteaux, J. Octave, 1987, European journal of pharmacology.

Pharmacological management of diabetes: recent progress and future perspective in daily drug treatment.

G. Emilien, M. Ponchon, J. Maloteaux, 1999, Pharmacology & therapeutics.

Current therapeutic uses and potential of β-adrenoceptor agonists and antagonists

G. Emilien, G. Emilion, J. Maloteaux, 1998, European Journal of Clinical Pharmacology.

How epileptogenic are the recent antibiotics?

P. Hantson, J. Maloteaux, P. Mahieu, 1999, Acta clinica Belgica.

Hypersensitivity of dopamine transmission in the rat striatum after treatment with the NMDA receptor antagonist amantadine

G. Page, J. Maloteaux, E. Hermans, 2002, Brain Research.

Sigma receptor characterized with (+)-[3H]-3-(3-hydroxyphenyl)-N-(1-propyl)-piperidine on C6 glioma cells is a putative K+ channel

J. Maloteaux, A. Jeanjean, P. Laduron, 1991, European Neuropsychopharmacology.

Identification of different β amyloid cDNAs cloned from the brain of a patient with sporadic alzheimer's disease

F. Sauvage, J. Maloteaux, J. Octave, 1989, Neurochemistry International.

CSF and serum metabolic profile of patients with Huntington's chorea: A study by high resolution proton NMR spectroscopy and HPLC

J. Vion-Dury, S. Confort-Gouny, P. Cozzone, 1993, Neuroscience Letters.

Subcellular distribution of receptor sites in human brain: Differentiation between heavy and light structures of high and low density

D. Scherman, P. Baudhuin, J. Maloteaux, 1995, Brain Research.

In vitro evidence for impaired neuroprotective capacities of adult mesenchymal stem cells derived from a rat model of familial amyotrophic lateral sclerosis (hSOD1G93A)

J. Maloteaux, E. Hermans, C. Boucherie, 2008, Experimental Neurology.

Benzodiazepine receptors in normal human brain, in Parkinson's disease and in progressive supranuclear palsy

Y. Agid, F. Javoy‐Agid, J. Maloteaux, 1988, Brain Research.

Altered expression of regulators of G-protein signaling (RGS) mRNAs in the striatum of rats undergoing dopamine depletion.

J. Maloteaux, E. Hermans, M. Geurts, 2003, Biochemical pharmacology.

Selective destruction of nigrostriatal dopaminergic neurons does not alter [3H]-ryanodine binding in rat striatum.

J. Maloteaux, M. Geurts, F. Noël, 2000, Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas.

Drug and transmitter receptors in human brain. Characterization and localization of serotonin, dopamine and adrenergic receptors.

J. Maloteaux, 1986, Acta neurologica Belgica.

Distinct effects of amantadine and memantine on dopaminergic transmission in the rat striatum

J. Maloteaux, E. Hermans, M. Peeters, 2003, Neuroscience Letters.

Apomorphine pharmacokinetics in Parkinsonism after intranasal and subcutaneous application

J. Maloteaux, A. Jeanjean, N. Verbeke, 2010, European Journal of Drug Metabolism and Pharmacokinetics.

Enhanced striatal dopamine D(2) receptor-induced [35S]GTPgammaS binding after haloperidol treatment.

J. Maloteaux, E. Hermans, M. Geurts, 1999, European journal of pharmacology.

Haemophilias: advances towards genetic engineering replacement therapy.

G. Emilien, A. Goodeve, J. Maloteaux, 2000, Clinical and laboratory haematology.

Down-regulation of 3H-lofentanil binding to opiate receptors in different cultured neuronal cells

J. Maloteaux, P. Laduron, J. Octave, 2004, Naunyn-Schmiedeberg's Archives of Pharmacology.

REGULATION OF μ-OPIATE RECEPTORS IN CULTURED NEURONS

J. Maloteaux, P. Laduron, J. Octave, 1987 .

Interaction of the COOH-terminal domain of the neurotensin receptor with a G protein does not control the phospholipase C activation but is involved in the agonist-induced internalization.

J. Maloteaux, E. Hermans, J. Octave, 1996, Molecular Pharmacology.

Trapping of labelled ligands in intact cells: a pitfall in binding studies.

J. Maloteaux, P. Laduron, A. Gossuin, 1983, Biochemical pharmacology.

Absence of dopamine and muscarinic receptors on human lymphocytes.

J. Maloteaux, P. Laduron, C. Waterkein, 1982, Archives internationales de pharmacodynamie et de therapie.

Unilateral induction of progenitors in the spinal cord of hSOD1G93A transgenic rats correlates with an asymmetrical hind limb paralysis

S. Schiffmann, J. Maloteaux, E. Hermans, 2006, Neuroscience Letters.

Cloning of the Beta Amyloid Peptide Gene in Alzheimer’s Disease

M. Vitek, J. Brucher, C. Rasool, 1988 .

Activation of VIP/PACAP type 2 receptor by the peptide histidine isoleucine in astrocytes influences GLAST‐mediated glutamate uptake

J. Maloteaux, E. Hermans, S. Goursaud, 2008, Journal of neurochemistry.

Distinct expression and regulation of the glutamate transporter isoforms GLT-1a and GLT-1b in cultured astrocytes from a rat model of amyotrophic lateral sclerosis (hSOD1G93A)

J. Maloteaux, E. Hermans, S. Goursaud, 2009, Neurochemistry International.

Absence of mutation in the beta-amyloid cDNAs cloned from the brains of three patients with sporadic Alzheimer's disease.

R. Bartus, M. Vitek, F. D. de Sauvage, 1988, Brain research.

Differentiation between ligand trapping into intact cells and binding on muscarinic receptors.

J. Maloteaux, A. Trouet, P. Laduron, 1984, Biochimica et biophysica acta.

Pharmacological characterisation of (E)-N-(3-iodoprop-2-enyl)-2β-carbomethoxy-3β-(4′-methylphenyl)nortropane (PE2I) binding to the rat neuronal dopamine transporter expressed in COS cells

G. Page, J. Maloteaux, E. Hermans, 2002, Neurochemistry International.

NMDA glutamatergic receptors, labelled with [3H]MK-801, in brain samples from drug-free depressed suicides

C. Katona, J. Maloteaux, R. Horton, 1993, Brain Research.

J. Maloteaux, E. Hermans, M. Najimi, 2002, FEBS letters.

Modulation of the neuronal dopamine transporter activity by the metabotropic glutamate receptor mGluR5 in rat striatal synaptosomes through phosphorylation mediated processes

G. Page, J. Maloteaux, E. Hermans, 2001, Journal of neurochemistry.

Benzodiazepine receptors on cultured neurons: Binding with different [3H]ligands on homogenized and intact cells

J. Maloteaux, A. Trouet, A. Gossuin, 1986, Neurochemistry International.

Opposite modulation of regulators of G protein signalling-2 (RGS2) and RGS4 expression by dopamine receptors in the rat striatum

J. Maloteaux, E. Hermans, M. Geurts, 2002, Neuroscience Letters.

Cloning of Different Amyloid Peptide Precursors from Brains of Patients with Alzheimer’s Disease

F. Sauvage, J. Maloteaux, J. Octave, 1989 .

Desensitization of neurotensin-induced phosphoinositide hydrolysis in transfected CHO cells.

J. Maloteaux, E. Hermans, 1996, Biochemical pharmacology.

CONSTRUCTION OF LAMBDA GT 11 cDNA LIBRARIES FROM POST-MORTEM HUMAN BRAINS

F. Sauvage, J. Maloteaux, J. Octave, 1987 .

Modification of neuronal cell adhesion affects the genetic expression of the A4 amyloid peptide precursor

F. Sauvage, J. Maloteaux, J. Octave, 1989, Brain Research.

Interaction of fluorescein derivatives with glibenclamide binding sites in rat brain

O. Feron, J. Maloteaux, J. Octave, 1995, Neuroscience Letters.

Sulfonylurea binding sites in normal human brain and in Parkinson's disease, progressive supranuclear palsy and Huntington's disease

Y. Agid, F. Javoy‐Agid, J. Maloteaux, 1994, Brain Research.

The dose-response relationship in phase I clinical trials and beyond: use, meaning, and assessment.

G. Emilien, W. V. van Meurs, J. Maloteaux, 2000, Pharmacology & therapeutics.

Lithium compared to valproic acid and carbamazepine in the treatment of mania: a statistical meta-analysis

G. Emilien, J. Maloteaux, A. Seghers, 1996, European Neuropsychopharmacology.

Different Subcellular Localization of Muscarinic and Serotonin (S2) Receptors in Human, Dog, and Rat Brain

J. Maloteaux, A. Trouet, P. Laduron, 1986, Journal of neurochemistry.

Short‐term disappearance of muscarinic cell surface receptors in carbachol‐induced desensitization

P. Pauwels, J. Maloteaux, P. Laduron, 1983, FEBS letters.

Mechanisms of regulation of neurotensin receptors.

J. Maloteaux, E. Hermans, 1998, Pharmacology & therapeutics.

Prospects for pharmacological intervention in Alzheimer disease.

K. Beyreuther, G. Emilien, C. Masters, 2000, Archives of neurology.

IL-1β-like Freund's adjuvant enhances axonal transport of opiate receptors in sensory neurons

J. Maloteaux, A. Jeanjean, P. Laduron, 1994, Neuroscience Letters.

Pharmacological management of epilepsy. Mechanism of action, pharmacokinetic drug interactions, and new drug discovery possibilities.

G. Emilien, J. Maloteaux, 1998, International journal of clinical pharmacology and therapeutics.

Agonist-induced muscarinic cholinergic receptor internalization, recycling and degradation in cultured neuronal cells. Cellular mechanisms and role in desensitization.

J. Maloteaux, E. Hermans, Emmanuel Hermans, 1994, Biochemical pharmacology.

Phospholipase C activation by neurotensin and neuromedin N in Chinese hamster ovary cells expressing the rat neurotensin receptor.

J. Maloteaux, E. Hermans, J. Octave, 1992, Brain research. Molecular brain research.

Alzheimer disease: mouse models pave the way for therapeutic opportunities.

K. Beyreuther, G. Emilien, C. Masters, 2000, Archives of neurology.

Distinct regions of C‐terminus of the high affinity neurotensin receptor mediate the functional coupling with pertussis toxin sensitive and insensitive G‐proteins

J. Maloteaux, E. Hermans, M. Najimi, 2002, FEBS letters.

Down-regulation of neurotensin receptors after ligand-induced internalization in rat primary cultured neurons

J. Maloteaux, E. Hermans, M. Geurts, 1997, Neurochemistry International.

Receptor mediated internalization of neurotensin in transfected Chinese hamster ovary cells.

J. Maloteaux, E. Hermans, J. Octave, 1994, Biochemical pharmacology.

Postnatal ontogeny of the rat brain neurotensin receptor mRNA

J. Maloteaux, E. Hermans, A. Jeanjean, 1993, Neuroscience Letters.

Rapid agonist-induced decrease of neurotensin receptors from the cell surface in rat cultured neurons.

J. Maloteaux, P. Laduron, J. Octave, 1991, Biochemical pharmacology.

Dopamine receptors--physiological understanding to therapeutic intervention potential.

S. Cragg, G. Emilien, J. Maloteaux, 1999, Pharmacology & therapeutics.

Interaction of the substance P receptor antagonist RP 67580 with the rat brain NK1 receptor expressed in transfected CHO cells.

J. Maloteaux, E. Hermans, L. Pradier, 1993, European journal of pharmacology.

Chimerization of astroglial population in the lumbar spinal cord after mesenchymal stem cell transplantation prolongs survival in a rat model of amyotrophic lateral sclerosis

P. Lavand'homme, J. Maloteaux, E. Hermans, 2009, Journal of neuroscience research.

3H-LOFENTANIL BINDING TO OPIATE RECEPTORS IN HUMAN CEREBELLUM

J. Maloteaux, G. Lustro, 1987 .

Neuroleptic binding to sigma receptors: Possible involvement in neuroleptic-induced acute dystonia

J. Maloteaux, A. Jeanjean, E. Laterre, 1997, Biological Psychiatry.

Biochemical and physiological evidences for antiserotonergic properties of naftidrofuryl.

J. Haiech, J. Maloteaux, P. Berta, 1986, Arzneimittel-Forschung.

Molecular and functional characterisation of glutamate transporters in rat cortical astrocytes exposed to a defined combination of growth factors during in vitro differentiation

J. Maloteaux, E. Hermans, Céline Vermeiren, 2005, Neurochemistry International.

In vitro differentiated neural stem cells express functional glial glutamate transporters

J. Maloteaux, E. Hermans, Céline Vermeiren, 2004, Neuroscience Letters.

Induction of glial glutamate transporters in adult mesenchymal stem cells

J. Maloteaux, E. Hermans, Céline Vermeiren, 2004, Journal of neurochemistry.

Loss of metabotropic glutamate receptor‐mediated regulation of glutamate transport in chemically activated astrocytes in a rat model of amyotrophic lateral sclerosis

Jean-Marie Maloteaux, Emmanuel Hermans, J. Maloteaux, 2006, Journal of neurochemistry.

Cloning of the cDNA from normal brain and brain of patients with Alzheimer's disease in the expression vector lambda GT 11

F. Sauvage, J. Maloteaux, J. Octave, 1988, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Lithium neurotoxicity at low therapeutic doses Hypotheses for causes and mechanism of action following a retrospective analysis of published case reports.

G. Emilien, J. Maloteaux, 1996, Acta neurologica Belgica.

Dopamine D3agonists

G. Emilien, Cécile Durlach, J. Maloteaux, 2001 .

Pharmacological blockade of dopamine D2 receptors by aripiprazole is not associated with striatal sensitization

A. Calas, J. Maloteaux, E. Hermans, 2010, Naunyn-Schmiedeberg's Archives of Pharmacology.

[3H]MK-801 binding to NMDA glutamatergic receptors in Parkinson's disease and progressive supranuclear palsy

Y. Agid, J. Maloteaux, F. Javoy, 1991, Brain Research.

The VPAC2 agonist peptide histidine isoleucine (PHI) up‐regulates glutamate transport in the corpus callosum of a rat model of amyotrophic lateral sclerosis (hSOD1G93A) by inhibiting caspase‐3 mediated inactivation of GLT‐1a

J. Maloteaux, E. Hermans, S. Goursaud, 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Pertussis toxin-sensitive modulation of glutamate transport by endothelin-1 type A receptors in glioma cells.

J. Maloteaux, E. Hermans, M. Najimi, 2005, Biochimica et biophysica acta.

Regional and subcellular localization in human brain of [3H]paroxetine binding, a marker of serotonin uptake sites

Marc Laruelle, M. Laruelle, J. Maloteaux, 1988, Biological Psychiatry.

Rapid desensitization of agonist-induced calcium mobilization in transfected PC12 cells expressing the rat neurotensin receptor.

J. Maloteaux, E. Hermans, P. Gailly, 1994, Biochemical and biophysical research communications.

Assessment of striatal D1 and D2 dopamine receptor-G protein coupling by agonist-induced [35S]GTP gamma S binding.

J. Maloteaux, E. Hermans, M. Geurts, 1999, Life sciences.

Circadian system and sleep anomaly in depression

G. Emilien, J. Maloteaux, 1999, Irish Journal of Psychological Medicine.

Characterization and regional distribution of serotonin S2-receptors in human brain

J. Maloteaux, P. Laduron, A. Schotte, 1983, Brain Research.

Dopamine D-3 agonists

G. Emilien, Cécile Durlach, J. Maloteaux, 2001 .

Functional dihydropyridine binding site associated with slow calcium channel in rat cultured neurones

J. Maloteaux, J. Octave, E. Laterre, 1988, Neuroscience Letters.

Paradoxical motor syndrome following a switch from atypical neuroleptics to aripiprazole.

E. Constant, J. Maloteaux, E. Hermans, 2007, The American journal of psychiatry.

Enhanced expression of the high affinity glutamate transporter GLT-1 in C6 glioma cells delays tumour progression in rat

J. Maloteaux, E. Hermans, N. Vanhoutte, 2009, Experimental Neurology.

Chronic treatment with certain antipsychotic drugs preserves upregulation of regulator of G-protein signalling 2 mRNA in rat striatum as opposed to c-fos mRNA

P. Pauwels, J. Maloteaux, M. Geurts, 2001, Neuroscience Letters.

Fractionation of human brain by differential and isopycnic equilibration techniques.

P. Baudhuin, J. Maloteaux, A. Jeanjean, 1997, Brain research. Brain research protocols.

Quantitative assessment of quinolinic acid-induced striatal toxicity in rats using radioligand binding assays.

J. Brotchi, M. Levivier, D. Togasaki, 1994, Neurological research.

Dopamine receptor-modulated [ 35 S ]GTPγS binding in striatum of 6-hydroxydopamine-lesioned rats

J. Maloteaux, E. Hermans, J. Cumps, 1999, Brain Research.

Life after sequencing.

G. Emilien, J. Maloteaux, D. Aveaux, 2001, Trends in Biotechnology.

Anticonvulsant activities of N-benzyloxycarbonylglycine after parenteral administration.

J. Poupaert, J. Maloteaux, D. Lambert, 1994, Neuroreport.

Agonist and antagonist modulation of [35S]‐GTPγS binding in transfected CHO cells expressing the neurotensin receptor

J. Maloteaux, E. Hermans, M. Geurts, 1997, British journal of pharmacology.

Solubilization of serotonin S2-receptors from human brain.

J. Maloteaux, P. Laduron, A. Schotte, 1984, European journal of pharmacology.

Targretin Improves Cognitive and Biological Markers in a Patient with Alzheimer's Disease.

R. Lhommel, C. Sindic, A. Ivanoiu, 2015, Journal of Alzheimer's disease : JAD.

Increased dopamine uptake in striatal synaptosomes after treatment of rats with amantadine.

G. Page, J. Maloteaux, E. Hermans, 2000, European journal of pharmacology.

Brain glucose utilization in band heterotopia: synaptic activity of "double cortex".

A. Bol, C. Grandin, A. D. De Volder, 1994, Pediatric neurology.

Regional and Cortical Laminar Distributions of Serotonin S2, Benzodiazepine, Muscarinic, and Dopamine D2 Receptors in Human Brain

J. Maloteaux, P. Laduron, J M Maloteaux, 1984, Journal of neurochemistry.

Distribution of monoaminergic, cholinergic, and GABAergic markers in the human cerebral cortex

Y. Agid, M. Ruberg, B. Scatton, 1989, Neuroscience.

Increasing the density of the D2L receptor and manipulating the receptor environment are required to evidence the partial agonist properties of aripiprazole

J. Maloteaux, E. Hermans, B. Koener, 2012, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

Lithium compared to valproic acid and carbamazepine in the treatment of mania: a statistical meta-analysis

G. Emilien, J. Maloteaux, A. Seghers, 1996, European Neuropsychopharmacology.

Decrease of serotonin‐S2 receptors in temporal cortex of patients with Parkinson's disease and progressive supranuclear palsy

Y. Agid, F. Javoy‐Agid, J. Maloteaux, 1988, Movement disorders : official journal of the Movement Disorder Society.

Effects of riluzole on the evolution of focal cerebral ischemia: a magnetic resonance imaging study

J. Thiran, B. Maldague, R. Demeure, 1997, Magnetic Resonance Materials in Physics, Biology and Medicine.