N. Beeley

发表

GPCRs: an update on structural approaches to drug discovery

N. Beeley, C. Sage, 2003 .

Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity.

Brian M. Smith, F. Menzaghi, P. Dosa, 2008, Journal of medicinal chemistry.

Synthesis of C- and N-functionalised derivatives of 1,4,7-triazacyclononane-1,4,7-triyltriacetic acid (NOTA), 1,4,7,10-tetra-azacyclododecane-1,4,7,10-tetrayltetra-acetic acid (DOTA), and diethylenenetriaminepenta-acetic acid (DTPA): bifunctional complexing agents for the derivatisation of antibodie

J. P. Cox, M. Eaton, N. Beeley, 1990 .

Discovery and SAR of new benzazepines as potent and selective 5-HT(2C) receptor agonists for the treatment of obesity.

Brian M. Smith, F. Menzaghi, N. Beeley, 2005, Bioorganic & medicinal chemistry letters.

Synthesis of a kinetically stable yttrium-90 labelled macrocycle–antibody conjugate

J. P. Cox, M. Eaton, R. Kataky, 1989 .

Towards tumour imaging with indium-111 labelled macrocycle–antibody conjugates

M. Eaton, N. Beeley, B. Boyce, 1989 .

An in vivo model for screening peptidomimetic inhibitors of gelatinase A.

S. Chander, B. Mason, N. Beeley, 1995, Journal of pharmaceutical sciences.

Gelatinase inhibitors and tumour metastasis

S. Chander, B. Mason, I. Hart, 1995 .

Potent and selective inhibitors of gelatinase-a 1. hydroxamic acid derivatives

B. Mason, N. Beeley, J. O'Connell, 1994 .

Potent, selective inhibitors of human gelatinase and their potential in the treatment of tumour metastases

S. Chander, B. Mason, I. Hart, 1994 .

Synthesis of C- and N-Functionalised Derivatives of 1,4,7-Triazacyclononane-1,4,7-triyltriacetic Acid (NOTA), 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetrayltetraacetic Acid (DOTA), and Diethylenenetriaminepentaacetic Acid (DTPA): Bif

J. P. Cox, M. Eaton, N. Beeley, 1990 .

Cephalosporin Nitrogen Mustard Carbamate prodrugs for “ADEPT”.

N. Beeley, F. Willenbrock, A. J. Pratt, 1991 .

Discovery of 4-(dimethylamino)quinazolines as potent and selective antagonists for the melanin-concentrating hormone receptor 1.

S. Chaki, T. Funakoshi, N. Beeley, 2005, Bioorganic & medicinal chemistry letters.

Discovery of 1-[3-(4-bromo-2-methyl-2h-pyrazol-3-yl)-4-methoxyphenyl]-3-(2,4-difluorophenyl)urea (nelotanserin) and related 5-hydroxytryptamine2A inverse agonists for the treatment of insomnia.

Hongmei Li, T. Kilduff, P. Dosa, 2010, Journal of medicinal chemistry.

SYNTHESES OF PGF 2α AND CLOPROSTENOL

N. Beeley, J. Holohan, J. K. Sutherland, 1982 .

SYNTHESES OF PGF2α AND CLOPROSTENOL

N. Beeley, J. Holohan, J. K. Sutherland, 1981 .

A general synthesis of N-substituted isothiazol-3(2H)-ones

N. Beeley, L. Harwood, P. Hedger, 1994 .

A revolution in drug discovery

A. Berger, N. Beeley, N Beeley, 2000, BMJ : British Medical Journal.

Structural studies on the [Bu(t)-Cys18](19-37)-fragment of human beta-calcitonin-gene-related peptide.

N. Beeley, S. Tendler, C. Bose, 1991, The Biochemical journal.

Novel oxidative elimination in a norbornyl iodide

N. Beeley, J. K. Sutherland, 1977 .

Potent and selective inhibitors of gelatinase-A 2. carboxylic and phosphonic acid derivatives

B. Mason, N. Beeley, B. Boyce, 1994 .

Discovery and structure-activity relationship of (1R)-8-chloro-2,3,4,5-tetrahydro-1-methyl-1H-3-benzazepine (Lorcaserin), a selective serotonin 5-HT2C receptor agonist for the treatment of obesity.

Brian M. Smith, F. Menzaghi, P. Dosa, 2008, Journal of medicinal chemistry.

Can peptides be mimicked?

Beeley, N. Beeley, 2000, Drug discovery today.