R. Arduini

发表

Successful shape-Based virtual screening: The discovery of a potent inhibitor of the type I TGFβ receptor kinase (TβRI)

C. Chuaqui, Juswinder Singh, Miki N. Newman, 2003 .

N-terminally PEGylated human interferon-beta-1a with improved pharmacokinetic properties and in vivo efficacy in a melanoma angiogenesis model.

A. Whitty, D. Baker, D. Lindner, 2006, Bioconjugate chemistry.

Cutting edge: role of STAT1, STAT3, and STAT5 in IFN-alpha beta responses in T lymphocytes.

M. David, D. Baker, R. Arduini, 2005, Journal of immunology.

Lock and chop: A novel method for the generation of a PICK1 PDZ domain and piperidine‐based inhibitor co‐crystal structure

J. Hus, K. Guckian, L. Silvian, 2018, Protein science : a publication of the Protein Society.

A novel site-directed mutant of myoglobin with an unusually high O2 affinity and low autooxidation rate.

Michael L. Quillin, J. Olson, T. Carver, 1994, The Journal of biological chemistry.

Xenogeneic bone marrow transplantation: I. Cloning, expression, and species specificity of porcine IL‐3 and granulocyte‐macrophage colony‐stimulating factor

M. Denaro, R. Hawley, R. Arduini, 1997 .

High-resolution crystal structures of distal histidine mutants of sperm whale myoglobin.

Michael L. Quillin, J. Olson, G. Phillips, 1994, Journal of molecular biology.

The Use of Virtual Screening in ALK5 Kinase Inhibitor Discovery and Validation of Orally Active ALK5 Kinase Inhibitors in Oncology

C. Chuaqui, Juswinder Singh, Miki N. Newman, 2008 .

Cutting Edge: Role of STAT1, STAT3, and STAT5 in IFN-αβ Responses in T Lymphocytes

M. David, D. Baker, R. Arduini, 2005, The Journal of Immunology.

Characterization of a soluble ternary complex formed between human interferon‐β‐1a and its receptor chains

Wei Cheng, D. Baker, R. Arduini, 1999, Protein science : a publication of the Protein Society.

SM16, an Orally Active TGF-&bgr; Type I Receptor Inhibitor Prevents Myofibroblast Induction and Vascular Fibrosis in the Rat Carotid Injury Model

C. Chuaqui, Juswinder Singh, Miki N. Newman, 2008, Arteriosclerosis, thrombosis, and vascular biology.

Enhanced potency of human Sonic hedgehog by hydrophobic modification.

A. Whitty, P. Weinreb, D. Baker, 2001, Biochemistry.

Expression, purification, and characterization of rat interferon-beta, and preparation of an N-terminally PEGylated form with improved pharmacokinetic parameters.

B. Domon, D. Baker, R. Arduini, 2004, Protein expression and purification.

Discovery of structural diverse reversible BTK inhibitors utilized to develop a novel in vivo CD69 and CD86 PK/PD mouse model.

George H Vandeveer, N. Powell, L. Silvian, 2022, Bioorganic & medicinal chemistry letters.

Regulation of STAT protein synthesis by c-Cbl

D. Bowtell, M. David, D. Baker, 2001, Oncogene.

Potent PDZ-Domain PICK1 Inhibitors that Modulate Amyloid Beta-Mediated Synaptic Dysfunction

R. Huganir, K. Rhodes, K. Guckian, 2018, Scientific Reports.

Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases

L. Silvian, D. Baker, V. Hong, 2010, Protein science : a publication of the Protein Society.

Environmental Technologies in the European Chemical Industry

Fabrizio Cesaroni, Roberta Arduini, F. Cesaroni, 2001 .

Successful shape-based virtual screening: the discovery of a potent inhibitor of the type I TGFbeta receptor kinase (TbetaRI).

Scott Bowes, Serene Josiah, Juswinder Singh, 2003, Bioorganic & medicinal chemistry letters.

Crystal structure of myoglobin form a synthetic gene

S. Sligar, G. Phillips, R. Arduini, 1990, Proteins.

Development and Diffusion of Environmental Technologies

F. Cesaroni, R. Arduini, 2004 .