Jun O. Liu

发表

Pentacyclic triterpenes. Part 3: Synthesis and biological evaluation of oleanolic acid derivatives as novel inhibitors of glycogen phosphorylase.

Luyong Zhang, Jun Chen, Jun O. Liu, 2006, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological evaluation of 2-(phenoxyaryl)-3-urea derivatives as novel P2Y1 receptor antagonists.

Hong Liu, Huaiyu Yang, Jingjing Peng, 2018, European journal of medicinal chemistry.

Conjugation of Uridine with Oleanolic Acid Derivatives as Potential Antitumor Agents

Zhenfeng Chen, Jun O. Liu, Ke-Guang Cheng, 2016, Chemical biology & drug design.

Synthesis and cytotoxic evaluation of several oleanolic acid–uracil/thymine conjugates

Zhenfeng Chen, Jun O. Liu, Hengshan Wang, 2016 .

Synthesis of acyl oleanolic acid-uracil conjugates and their anti-tumor activity

Zhenfeng Chen, Jun O. Liu, Ke-Guang Cheng, 2016, Chemistry Central Journal.

Synthesis and cytotoxicity evaluation of oleanolic acid derivatives.

Jun O. Liu, Hongbin Sun, Xiaoan Wen, 2013, Bioorganic & medicinal chemistry letters.

Effect of olive pomace extracts on hyperlipidaemia

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2011, Natural product research.

Discovery of Novel Potent Muscarinic M3 Receptor Antagonists with Proper Plasma Stability by Structural Recombination of Marketed M3 Antagonists

Jun O. Liu, Hongbin Sun, Xiaoan Wen, 2017, ChemMedChem.

Tethered derivatives of D-glucose and pentacyclic triterpenes for homo/heterobivalent inhibition of glycogen phosphorylase

Jun O. Liu, Hongbin Sun, L. Somsák, 2010 .

Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase.

Hualiang Jiang, Xiao-min Luo, Hong Liu, 2012, European journal of medicinal chemistry.

Novel furoxan NO-donor pemetrexed derivatives: design, synthesis, and preliminary biological evaluation

Can Zhang, Huiping Zhou, Jun O. Liu, 2009, Medicinal Chemistry Research.

Maslinic acid reduces blood glucose in KK-Ay mice.

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2007, Biological & pharmaceutical bulletin.

Terpenoids. III: Synthesis and biological evaluation of 23-hydroxybetulinic acid derivatives as novel inhibitors of glycogen phosphorylase.

Luyong Zhang, W. Ye, Jun O. Liu, 2009, Bioorganic & medicinal chemistry letters.

New Pentacyclic Triterpenes from Gypsophila oldhamiana and Their Biological Evaluation as Glycogen Phosphorylase Inhibitors

Jun O. Liu, L. Kong, Jianguang Luo, 2008, Chemistry & biodiversity.

Synthesis of oleanolic acid dimers linked at C-28 and evaluation of anti-tumor activity.

Zhenfeng Chen, Jun O. Liu, Ke-Guang Cheng, 2015, European journal of medicinal chemistry.

Effects of oleanolic acid and maslinic acid on hyperlipidemia

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2007 .

Synthesis and Evaluation of Novel Oleanolic Acid Derivatives as Potential Antidiabetic Agents

Luyong Zhang, Jun O. Liu, X. Jia, 2014, Chemical biology & drug design.

Benzamide derivatives as dual-action hypoglycemic agents that inhibit glycogen phosphorylase and activate glucokinase.

Hualiang Jiang, Honglin Li, Hong Liu, 2009, Bioorganic & medicinal chemistry.

Structural optimization and biological evaluation of 1,5-disubstituted pyrazole-3-carboxamines as potent inhibitors of human 5-lipoxygenase

Hualiang Jiang, Hong Liu, M. Zheng, 2016, Acta pharmaceutica Sinica. B.

Asiatic acid preserves beta cell mass and mitigates hyperglycemia in streptozocin‐induced diabetic rats

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2010, Diabetes/metabolism research and reviews.

Synthesis and biological evaluation of ticagrelor derivatives as novel antiplatelet agents.

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2012, Bioorganic & medicinal chemistry letters.

Pentacyclic triterpenes. Part 5: synthesis and SAR study of corosolic acid derivatives as inhibitors of glycogen phosphorylases.

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2007, Bioorganic & medicinal chemistry letters.

Pentacyclic triterpenes. Part 1: the first examples of naturally occurring pentacyclic triterpenes as a new class of inhibitors of glycogen phosphorylases.

Luyong Zhang, Jun O. Liu, Guan-zhong Wu, 2005, Bioorganic & medicinal chemistry letters.

Design, synthesis, and biological evaluation of (2E)-(2-oxo-1, 2-dihydro-3H-indol-3-ylidene)acetate derivatives as anti-proliferative agents through ROS-induced cell apoptosis.

Jun O. Liu, Hongbin Sun, Haoliang Yuan, 2016, European journal of medicinal chemistry.

Discovery of highly potent DPP-4 inhibitors by hybrid compound design based on linagliptin and alogliptin.

Jun O. Liu, Hongbin Sun, L. Kong, 2014, European journal of medicinal chemistry.

Synthesis and HMG-CoA reductase inhibition of 2-cyclopropyl-4-thiophenyl-quinoline mevalonolactones.

Jun O. Liu, Weicheng Zhou, Shikui Zhao, 2009, Bioorganic & medicinal chemistry.

Synthesis of Nucleoside Conjugates as Potential Inhibitors of Glycogen Phosphorylase

Jun O. Liu, Hongbin Sun, Juan Xie, 2010 .

Efficient synthesis of morolic acid and related triterpenes starting from betulin

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2009 .

Pentacyclic triterpenes. Part 2: Synthesis and biological evaluation of maslinic acid derivatives as glycogen phosphorylase inhibitors.

Luyong Zhang, Jun O. Liu, Xiao-ming Wu, 2006, Bioorganic & medicinal chemistry letters.

Synthesis and anticancer evaluation of benzyloxyurea derivatives.

Jun O. Liu, Chao Liu, Wenxue Sun, 2014, Chemical & pharmaceutical bulletin.

Synthesis of glucoconjugates of oleanolic acid as inhibitors of glycogen phosphorylase.

Honglin Li, Xiaofeng Liu, Jun O. Liu, 2009, Carbohydrate research.

Naturally occurring pentacyclic triterpenes as inhibitors of glycogen phosphorylase: synthesis, structure-activity relationships, and X-ray crystallographic studies.

S. Zographos, N. Oikonomakos, D. Leonidas, 2008, Journal of medicinal chemistry.

Synthesis and Biological Evaluation of Asiatic Acid Derivatives as Inhibitors of Glycogen Phosphorylases

Luyong Zhang, Jun Chen, Jun O. Liu, 2009, Chemistry & biodiversity.

Synthesis and Biological Evaluation of Arjunolic Acid, Bayogenin, Hederagonic Acid and 4-Epi-hederagonic Acid as Glycogen Phosphorylase Inhibitors

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2010 .

Efficient access to isomeric 2,3-dihydroxy lupanes: first synthesis of alphitolic acid

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2009 .

Effects of Oleanolic Acid and Maslinic Acid on Glucose and Lipid Metabolism: Implications for the Beneficial Effects of Olive Oil on Health

R. Rajendram, Luyong Zhang, Jun O. Liu, 2010 .

Efficient synthesis and biological evaluation of epiceanothic acid and related compounds.

Luyong Zhang, Keduo Qian, K. Lee, 2011, Bioorganic & medicinal chemistry letters.

Synthesis of 3-deoxypentacyclic triterpene derivatives as inhibitors of glycogen phosphorylase.

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2009, Journal of natural products.

Practical Synthesis of α‐Amyrin, β‐Amyrin, and Lupeol: The Potential Natural Inhibitors of Human Oxidosqualene Cyclase

Jun O. Liu, Hongbin Sun, Xiaoan Wen, 2017, Archiv der Pharmazie.

Hypolipidemic effect of oleanolic acid is mediated by the miR‐98‐5p/PGC‐1β axis in high‐fat diet‐induced hyperlipidemic mice

Siyu Chen, Jun O. Liu, Wenxiang Zhang, 2017, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

Synthesis and evaluation of in vitro anticancer activity of novel solasodine derivatives

Jun O. Liu, Hongbin Sun, Feiran Zhang, 2010 .

N-benzylpiperidinol derivatives as novel USP7 inhibitors: Structure-activity relationships and X-ray crystallographic studies.

Jun O. Liu, Hongbin Sun, Hui Chen, 2020, European journal of medicinal chemistry.

Design and synthesis of novel photoaffinity probes for study of the target proteins of oleanolic acid.

Jun O. Liu, Hongbin Sun, Yingxia Zhang, 2012, Bioorganic & medicinal chemistry letters.

Synthesis and Biological Evaluation of Novel Pentacyclic Triterpene Derivatives as Potential PPARγ Agonists

Jun O. Liu, Hongbin Sun, Hequan Yao, 2012 .

Synthesis of Oleanolic Acid Dimers as Inhibitors of Glycogen Phosphorylase

Jun O. Liu, Hongbin Sun, Juan Xie, 2010, Chemistry & biodiversity.

Pentacyclic Triterpenes. Part 3. Synthesis and Biological Evaluation of Oleanolic Acid Derivatives as Novel Inhibitors of Glycogen Phosphorylase.

Luyong Zhang, Jun Chen, Jun O. Liu, 2006 .

Pentacyclic Triterpenes. Part 1. The First Examples of Naturally Occurring Pentacyclic Triterpenes as a New Class of Inhibitors of Glycogen Phosphorylases.

Luyong Zhang, Jun O. Liu, Guan-zhong Wu, 2006 .

Combination Therapy with Oleanolic Acid and Metformin as a Synergistic Treatment for Diabetes

Jun O. Liu, Hongbin Sun, Yu-peng Chen, 2015, Journal of diabetes research.

Practical synthesis of bredemolic acid, a natural inhibitor of glycogen phosphorylase.

Jun O. Liu, Hongbin Sun, Juan Xie, 2008, Journal of natural products.

Water‐soluble poly(ethylene glycol) prodrug of pemetrexed: Synthesis, characterization, and preliminary cytotoxicity

Can Zhang, Jun O. Liu, Peng Zhang, 2009 .

The STING antagonist H‐151 ameliorates psoriasis via suppression of STING/NF‐κB‐mediated inflammation

Jun O. Liu, Hongbin Sun, Xiaoan Wen, 2021, British journal of pharmacology.

Exploration of the molecular architecture of the orthosteric binding site in the α4β2 nicotinic acetylcholine receptor with analogs of 3-(dimethylamino)butyl dimethylcarbamate (DMABC) and 1-(pyridin-3-yl)-1,4-diazepane.

Jun O. Liu, B. Frølund, J. V. van Muijlwijk-Koezen, 2015, European journal of medicinal chemistry.

Discovering benzamide derivatives as glycogen phosphorylase inhibitors and their binding site at the enzyme.

Hualiang Jiang, Honglin Li, Hong Liu, 2007, Bioorganic & medicinal chemistry.

Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies.

Hualiang Jiang, Honglin Li, Hong Liu, 2011, European journal of medicinal chemistry.

Transcriptional regulation of lipid biosynthesis, related target validation and drug discovery

Jun O. Liu, Hongbin Sun, Chao Lin, 2015 .

Discovery of pentacyclic triterpene 3β-ester derivatives as a new class of cholesterol ester transfer protein inhibitors.

Jun O. Liu, Hongbin Sun, Xinyi He, 2017, European journal of medicinal chemistry.

Synthesis and Biological Evaluation of Arjunolic Acid, Bayogenin, Hederagonic Acid and 4- Epi -hederagonic Acid as Glycogen Phosphorylase Inhibitors: Synthesis and Biological Evaluation of Arjunolic Acid, Bayogenin, Hederagonic Acid and 4- Epi -hederagonic Acid as Glycogen Phosphorylase Inhibitors

Luyong Zhang, Jun O. Liu, Hongbin Sun, 2011 .

Synthesis and Biological Evaluation of Novel Pyrazolo[4,3‐b]oleanane Derivatives as Inhibitors of Glycogen Phosphorylase

Luyong Zhang, Jun Chen, Jun O. Liu, 2008, Chemistry & biodiversity.

New Pentacyclic Triterpenes from Gypsophila oldhamiana and Their Biological Evaluation as Glycogen Phosphorylase Inhibitors

Jun O. Liu, L. Kong, Jian-guang Luo, 2008, Chemistry & biodiversity.