S. Mountford

发表

Substituted 1-methyl-4-phenylpyrrolidin-2-ones - Fragment-based design of N-methylpyrrolidone-derived bromodomain inhibitors.

R. Johnstone, I. Jennings, P. Thompson, 2020, European journal of medicinal chemistry.

Heterodimeric analogues of the potent Y1R antagonist 1229U91, lacking one of the pharmacophoric C-terminal structures, retain potent Y1R affinity and show improved selectivity over Y4R.

N. Holliday, S. Briddon, P. Thompson, 2020, Journal of medicinal chemistry.

Identification and development of specific inhibitors for insulin‐regulated aminopeptidase as a new class of cognitive enhancers

M. Parker, J. Holien, P. Thompson, 2011, British journal of pharmacology.

Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation

C. Gachet, I. Jennings, P. Thompson, 2020, Science Translational Medicine.

Synthesis and elaboration of N-methylpyrrolidone as an acetamide fragment substitute in bromodomain inhibition.

R. Johnstone, I. Jennings, P. Thompson, 2019, Bioorganic & medicinal chemistry.

Morpholinone mediated oxazolone‐free C‐terminus amide coupling permitting a convergent strategy for peptide synthesis

S. Mountford, L. Harwood, R. Yan, 2009, Journal of peptide science : an official publication of the European Peptide Society.

Identification of a Cyanine-Dye Labeled Peptidic Ligand for Y1R and Y4R, Based upon the Neuropeptide Y C-Terminal Analogue, BVD-15.

Lei Zhang, H. Herzog, N. Holliday, 2016, Bioconjugate chemistry.

Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922).

David M. Shackleford, I. Jennings, P. Thompson, 2016, European journal of medicinal chemistry.

Class II but Not Second Class-Prospects for the Development of Class II PI3K Inhibitors.

I. Jennings, P. Thompson, S. Mountford, 2015, ACS medicinal chemistry letters.

Synthetic routes to the Neuropeptide Y Y1 receptor antagonist 1229U91 and related analogues for SAR studies and cell-based imaging.

Lei Zhang, H. Herzog, N. Holliday, 2014, Organic & biomolecular chemistry.

Development of single and mixed isoform selectivity PI3Kδ inhibitors by targeting Asn836 of PI3Kδ.

Michelle S. Miller, I. Jennings, P. Thompson, 2016, Bioorganic & medicinal chemistry letters.

Synthesis and biological evaluation of a novel photo-activated histone deacetylase inhibitor.

A. Dear, H. B. Liu, S. Mountford, 2020, Bioorganic & medicinal chemistry letters.

Beta amino acid‐modified and fluorescently labelled kisspeptin analogues with potent KISS1R activity

S. Moriya, P. Thompson, D. Chalmers, 2016, Journal of peptide science : an official publication of the European Peptide Society.

Synthesis of N-heterocyclic ligands for use in affinity and mixed mode chromatography

Milton T. W. Hearn, Eva M. Campi, M. Hearn, 2011 .

Synthesis, structure-activity relationships and brain uptake of a novel series of benzopyran inhibitors of insulin-regulated aminopeptidase.

Michael W Parker, Jessica K Holien, M. Parker, 2014, Journal of medicinal chemistry.

(S)-(−)-Fluorenylethylchloroformate (FLEC); preparation using asymmetric transfer hydrogenation and application to the analysis and resolution of amines

D. Manallack, P. Thompson, D. Chalmers, 2019, Tetrahedron.

S→N type Smiles rearrangement of the aminoethanethiol moiety attached to heterocyclic compounds

M. Hearn, E. Campi, S. Mountford, 2010 .

Optically Pure, Structural, and Fluorescent Analogues of a Dimeric Y4 Receptor Agonist Derived by an Olefin Metathesis Approach.

N. Holliday, P. Thompson, S. Mountford, 2016, Journal of medicinal chemistry.

Design, synthesis and evaluation of pyridine-based chromatographic adsorbents for antibody purification.

M. Hearn, S. Mountford, A. Robinson, 2014, Journal of chromatography. A.

The first total synthesis and solution structure of a polypeptin, PE2, a cyclic lipopeptide with broad spectrum antibiotic activity.

R. Nation, T. Velkov, Jian Li, 2017, Organic & biomolecular chemistry.

N‐Heterocyclic‐based adsorbents for antibody purification—effect of ligand structure

A. Bhagwat, E. Campi, S. Mountford, 2014, Journal of molecular recognition : JMR.

Application of a sulfoxonium ylide electrophile to generate cathepsin X-selective activity-based probes.

M. Hoang, N. Bunnett, P. Thompson, 2020, ACS chemical biology.

Propargyloxyproline Regio- and Stereoisomers for Click-Conjugation of Peptides: Synthesis and Application in Linear and Cyclic Peptides

M. Parker, J. Wielens, Lei Zhang, 2015 .

Design, Development, In Vitro and Preliminary In Vivo Evaluation of a Novel Photo-Angioplasty Device: Lumi-Solve

A. Dear, D. Kaye, J. Forsythe, 2021, Cardiovascular Engineering and Technology.

Synthesis of “Difficult” Fluorescence Quenched Substrates of Granzyme C

P. Bird, P. Thompson, R. Pike, 2010, International Journal of Peptide Research and Therapeutics.

The first total synthesis and solution structure of a polypeptin, PE2, a cyclic lipopeptide with broad spectrum antibiotic activity.

R. Nation, T. Velkov, Jian Li, 2017, Organic & biomolecular chemistry.

Synthesis of BVD15 Peptide Analogues as Models for Radioligands in Tumour Imaging

Lei Zhang, I. Lee, H. Herzog, 2013, International Journal of Peptide Research and Therapeutics.