Yong Tang

发表

Development of methyl isoxazoleazepines as inhibitors of BET.

R. Cummings, P. Sandy, Y. Leblanc, 2015, Bioorganic & medicinal chemistry letters.

GNE-371, a Potent and Selective Chemical Probe for the Second Bromodomains of Human Transcription-Initiation-Factor TFIID Subunit 1 and Transcription-Initiation-Factor TFIID Subunit 1-like.

H. Jayaram, F. A. Romero, R. Cummings, 2018, Journal of medicinal chemistry.

Inhibition of bromodomain-containing protein 9 for the prevention of epigenetically-defined drug resistance.

D. Stokoe, P. Sandy, Steffan Vartanian, 2017, Bioorganic & medicinal chemistry letters.

Diving into the Water: Inducible Binding Conformations for BRD4, TAF1(2), BRD9, and CECR2 Bromodomains.

Andrew C Good, Vickie Tsui, Jian Wang, 2016, Journal of medicinal chemistry.

A structure-based design of new C2- and C13-substituted taxanes: tubulin binding affinities and extended quantitative structure-activity relationships using comparative binding energy (COMBINE) analysis.

F. Gago, A. Morreale, J. Klett, 2013, Organic & biomolecular chemistry.

GNE-064: A Potent, Selective, and Orally Bioavailable Chemical Probe for the Bromodomains of SMARCA2 and SMARCA4 and the Fifth Bromodomain of PBRM1.

A. Good, P. Sandy, Y. Leblanc, 2022, Journal of medicinal chemistry.

GNE-886: A Potent and Selective Inhibitor of the Cat Eye Syndrome Chromosome Region Candidate 2 Bromodomain (CECR2).

P. Sandy, H. Jayaram, R. Sims, 2017, ACS medicinal chemistry letters.

Modification of C-seco taxoids through ring tethering and substituent replacement leading to effective agents against tumor drug resistance mediated by βIII-Tubulin and P-glycoprotein (P-gp) overexpressions.

D. Lucena‐Agell, I. Barasoain, Yong Tang, 2017, European journal of medicinal chemistry.

Solamargine Inhibits the Development of Hypopharyngeal Squamous Cell Carcinoma by Decreasing LncRNA HOXA11-As Expression

J. Hou, Dai Yuan, Wu Song, 2022, Frontiers in Pharmacology.

Discovery of Benzotriazolo[4,3-d][1,4]diazepines as Orally Active Inhibitors of BET Bromodomains.

P. Sandy, Y. Leblanc, H. Jayaram, 2016, ACS medicinal chemistry letters.

A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.

M. Oppikofer, A. Cochran, E. M. Flynn, 2015, Structure.

Water molecules in protein–ligand interfaces. Evaluation of software tools and SAR comparison

Yong Tang, Eva Nittinger, Paul Gibbons, 2019, Journal of Computer-Aided Molecular Design.

A Subset of Human Bromodomains Recognizes Butyryllysine and Crotonyllysine Histone Peptide Modifications.

M. Oppikofer, Oscar W. Huang, S. Bellon, 2015, Structure.