Han-Li Huang

发表

4-Indolyl-N-hydroxyphenylacrylamides as potent HDAC class I and IIB inhibitors in vitro and in vivo.

S. Pan, Samir Mehndiratta, Ruei-Shian Wang, 2017, European journal of medicinal chemistry.

Phenyl Benzenesulfonylhydrazides Exhibit Selective Indoleamine 2,3-Dioxygenase Inhibition with Potent in Vivo Pharmacodynamic Activity and Antitumor Efficacy.

Yi-Hui Peng, Y. Chao, Su-Ying Wu, 2016, Journal of medicinal chemistry.

EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

P. Wei, Ya‐Wen Cheng, S. Pan, 2021, Cell & bioscience.

1,4-Naphthoquinones as inhibitors of Itch, a HECT domain-E3 ligase, and tumor growth suppressors in multiple myeloma.

Y. Yen, S. Pan, Han-Li Huang, 2017, European journal of medicinal chemistry.

An oral quinoline derivative, MPT0B392, causes leukemic cells mitotic arrest and overcomes drug resistant cancer cells

Chia-Ron Yang, C. Teng, Han-Li Huang, 2017, Oncotarget.

1-Aroylindoline-hydroxamic acids as anticancer agents, inhibitors of HSP90 and HDAC.

S. Pan, Han-Li Huang, Chih-Jou Su, 2018, European journal of medicinal chemistry.

1‐Arylsulfonyl‐5‐(N‐hydroxyacrylamide)indolines Histone Deacetylase Inhibitors Are Potent Cytokine Release Suppressors

Chia-Ron Yang, C. Teng, T. Yeh, 2013, Chembiochem : a European journal of chemical biology.

Non-epigenetic function of HDAC8 in regulating breast cancer stem cells by maintaining Notch1 protein stability

S. Kulp, C. Chen, C. Teng, 2015, Oncotarget.

Synthesis and biological evaluation of 1-arylsulfonyl-5-(N-hydroxyacrylamide)indoles as potent histone deacetylase inhibitors with antitumor activity in vivo.

C. Chen, C. Teng, S. Pan, 2012, Journal of medicinal chemistry.

2-(Phenylsulfonyl)quinoline N-hydroxyacrylamides as potent anticancer agents inhibiting histone deacetylase.

Chia-Ron Yang, Samir Mehndiratta, Han-Li Huang, 2016, European journal of medicinal chemistry.

Identification of a dual FLT3 and MNK2 inhibitor for acute myeloid leukemia treatment using a structure-based virtual screening approach.

J. Hsieh, S. Pan, Han-Li Huang, 2022, Bioorganic chemistry.

Investigation of Selected Flavonoid Derivatives as Potent FLT3 Inhibitors for the Potential Treatment of Acute Myeloid Leukemia.

S. Pan, Han-Li Huang, Yi-Wen Wu, 2021, Journal of natural products.

Lanatoside C, a cardiac glycoside, acts through protein kinase Cδ to cause apoptosis of human hepatocellular carcinoma cells

Yu-Wei Chang, C. Teng, S. Pan, 2017, Scientific Reports.

ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5.

Zhenghua Luo, Tae Jin Lee, Yong Peng, 2016, Cancer cell.

Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury

S. Pan, Han-Li Huang, K. Hsu, 2020, BMC Pharmacology and Toxicology.

Biological Evaluation of Selected Flavonoids as Inhibitors of MNKs Targeting Acute Myeloid Leukemia.

S. Pan, Han-Li Huang, Yi-Wen Wu, 2020, Journal of natural products.

Novel oral histone deacetylase inhibitor, MPT0E028, displays potent growth-inhibitory activity against human B-cell lymphoma in vitro and in vivo

C. Teng, S. Pan, Chieh-Yu Peng, 2014, Oncotarget.

Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer.

C. Shapiro, M. Wicha, S. Kulp, 2016, Carcinogenesis.

A Novel Selective JAK2 Inhibitor Identified Using Pharmacological Interactions

J. Hsieh, S. Pan, Han-Li Huang, 2018, Front. Pharmacol..

LTP-1, a novel antimitotic agent and Stat3 inhibitor, inhibits human pancreatic carcinomas in vitro and in vivo

C. Teng, S. Pan, Han-Li Huang, 2016, Scientific Reports.

TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis

Ya‐Wen Cheng, S. Pan, Tsui-Chin Huang, 2019, Theranostics.

Isoindoline scaffold-based dual inhibitors of HDAC6 and HSP90 suppressing the growth of lung cancer in vitro and in vivo.

S. Pan, Han-Li Huang, J. Liou, 2020, European journal of medicinal chemistry.

TW-01, a piperazinedione-derived compound, inhibits Ras-mediated cell proliferation and angioplasty-induced vascular restenosis.

C. Teng, S. Pan, Chieh-Yu Peng, 2016, Toxicology and applied pharmacology.

EGFL6 promotes colorectal cancer cell growth and mobility and the anti‐cancer property of anti-EGFL6 antibody

Ya‐Wen Cheng, S. Pan, Han-Li Huang, 2020, Cell & Bioscience.

Function of Integrin-Linked Kinase in Modulating the Stemness of IL-6–Abundant Breast Cancer Cells by Regulating γ-Secretase–Mediated Notch1 Activation in Caveolae12

C. Shapiro, M. Wicha, S. Kulp, 2015, Neoplasia.

Investigating the potential effects of selective histone deacetylase 6 inhibitor ACY1215 on infarct size in rats with cardiac ischemia-reperfusion injury

S. Pan, Han-Li Huang, K. Hsu, 2020, BMC Pharmacology and Toxicology.

Potential Effects of CXCL9 and CCL20 on Cardiac Fibrosis in Patients with Myocardial Infarction and Isoproterenol-Treated Rats

Shui-Tein Chen, S. Pan, Han-Li Huang, 2019, Journal of clinical medicine.

MPT0G066, a novel anti-mitotic drug, induces JNK-independent mitotic arrest, JNK-mediated apoptosis, and potentiates antineoplastic effect of cisplatin in ovarian cancer

C. Teng, S. Pan, Han-Li Huang, 2016, Scientific Reports.

ERK Activation Globally Downregulates miRNAs through Phosphorylating Exportin-5.

C. Croce, F. Lovat, M. Fassan, 2016, Cancer cell.

Anticancer Study of a Novel Pan-HDAC Inhibitor MPT0G236 in Colorectal Cancer Cells

Chia-Ron Yang, S. Pan, Han-Li Huang, 2023, International journal of molecular sciences.

Integrin-linked kinase as a novel molecular switch of the IL-6-NF-κB signaling loop in breast cancer.

C. Shapiro, M. Wicha, S. Kulp, 2016, Carcinogenesis.