I. Dubé

发表

The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB–binding protein

C. Disteche, F. Behm, D. Horsman, 1996, Nature Genetics.

Gene Marking and the Biology of Hematopoietic Cell Transfer in Human Clinical Trials

A. Stewart, R. Hawley, I. Dubé, 1999 .

Recent progress in gene transfer into hematopoietic stem cells.

A. Stewart, C. Lutzko, I. Dubé, 1999, Critical reviews in oncology/hematology.

Retrovirus-mediated gene transfer into human hematopoietic stem cells

A. Stewart, C. Lutzko, I. Dubé, 1998, Journal of Molecular Medicine.

Acquisition of additional primary chromosome abnormalities in the course of karyotype evolution in a case of FAB-M2 acute leukemia.

I. Dubé, P. Pinkerton, D. Battaglia, 1989, Cancer genetics and cytogenetics.

Autocrine and paracrine growth control by granulocyte-monocyte colony-stimulating factor of acute lymphoblastic leukemia cells.

Paulo N. Correa, M. Freedman, I. Dubé, 1993, Blood.

Autocrine and paracrine growth control by granulocyte-monocyte colony-stimulating factor of acute lymphoblastic leukemia cells

Paulo N. Correa, M. Freedman, I. Dubé, 1993 .

BCL3 rearrangements and t(14;19) in chronic lymphocytic leukemia and other B‐cell malignancies: A molecular and cytogenetic study

J. Rowley, H. Ohno, B. Hecht, 1997, Genes, chromosomes & cancer.

Genetically corrected autologous stem cells engraft, but host immune responses limit their utility in canine alpha-L-iduronidase deficiency.

C. Lutzko, D. Kohn, I. Dubé, 1999, Blood.

Deregulation of NPM and PLZF in a variant t(5;17) case of acute promyelocytic leukemia

J. Licht, R. Wells, S. Kamel‐Reid, 1999, Oncogene.

Acute lymphoblastic leukemia with T(4;11) translocation after osteogenic sarcoma

I. Dubé, J. Kapelushnik, P. Wilson, 1991, Cancer.

Diagnosis of acute promyelocytic leukaemia by RT‐PCR: detection of PML‐RARA and RARA‐PML fusion transcripts

T. Lister, A. Hagemeijer, T. Fioretos, 1992, British journal of haematology.

Dysregulated expression of mitotic regulators is associated with B-cell lymphomagenesis in HOX11-transgenic mice

M. Lim, M. R. Hough, P. Jolicoeur, 2006, Oncogene.

Induction of tolerance to immunogenic tumor antigens associated with lymphomagenesis in HOX11 transgenic mice.

M. R. Hough, I. Dubé, M. Reis, 2000, Proceedings of the National Academy of Sciences of the United States of America.

A phase I study of adenovirus mediated gene transfer of interleukin 2 cDNA into metastatic breast cancer or melanoma.

F. Graham, A. Stewart, N. Lassam, 1997, Human gene therapy.

Background and update to a phase I trial of stem cell gene marking in multiple myeloma

H. Prince, I. Dubé, A. Stewart, 1996 .

A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14)

S. Kamel‐Reid, J. Minowada, M. Lu, 1991 .

Phenotypic heterogeneity in three cases of lymphoid malignancy with chromosomal translocations in 14q11.

I. Dubé, M. Greenberg, 1986, Cytogenetics and cell genetics.

Gene expression profiling in the inductive human hematopoietic microenvironment.

M. R. Hough, Edwin Chen, I. Dubé, 2004, Biochemical and biophysical research communications.

Human hematopoietic progenitors engraft in fetal canine recipients and expand with neonatal injection of fibroblasts expressing human hematopoietic cytokines.

M. R. Hough, C. Lutzko, I. Dubé, 2002, Experimental hematology.

Engraftment of gene-marked hematopoietic progenitors in myeloma patients after transplant of autologous long-term marrow cultures.

B. Peck, A. Stewart, J. Tisdale, 1999, Human gene therapy.

In vitro and in vivo effects of deferoxamine in neonatal acute leukemia

Z. Estrov, E. Gelfand, M. Freedman, 1987 .

Residual juvenile chronic myelogenous leukemia cells detected in peripheral blood during clinical remission.

Z. Estrov, M. Freedman, I. Dubé, 1987, Blood.

A phase I study of autologous bone marrow transplantation with stem cell gene marking in multiple myeloma.

S. Kamel‐Reid, A. Stewart, A. Keating, 1995, Human gene therapy.

In vivo adenoviral-mediated gene transfer of interleukin-2 in cutaneous plasmacytoma.

F. Graham, A. Stewart, J. Gauldie, 1998, Blood.

Preclinical assessment of human hematopoietic progenitor cell transduction in long-term marrow cultures.

S. Kamel‐Reid, A. Stewart, C. Lutzko, 1996, Human gene therapy.

Adoptive transfer of genetically modified hematopoietic stem cells

I. Dubé, A. Stewart, 1996 .

Molecular and serological examination of the relationship of human herpesvirus 8 to multiple myeloma: orf 26 sequences in bone marrow stroma are not restricted to myeloma patients and other regions of the genome are not detected.

A. Stewart, J. Tisdale, C. Dunbar, 1998, Blood.

"Jumping" translocations involving band 3q13.3 in a case of acute monocytic leukemia.

I. Dubé, P. Pinkerton, J. Senn, 1991, Cancer genetics and cytogenetics.

Trisomy 14q in myelodysplastic syndromes.

I. Dubé, P. Pinkerton, J. Senn, 1990, Cancer genetics and cytogenetics.

Neutrophilic myelofibrosis presenting as philadelphia chromosome negative BCR non‐rearranged chronic myeloid leukemia

A. Keating, I. Dubé, K. Carstairs, 1990, American journal of hematology.

Isochromosome 7q as the sole abnormality in an unusual case of T-cell lineage malignancy.

I. Dubé, K. Carstairs, D. Bailey, 1990, Hematologic pathology.

Gene Rearrangement Studies in the Assessment of Lymphoid Neoplasias.

I. Dubé, M. Reis, 1991, Leukemia & lymphoma.

A novel method for the direct quantification of gene transfer into cells using PCR in situ

C. Catzavelos, A. Stewart, I. Dubé, 1998, Gene Therapy.

Cytogenetic analysis of single hemopoietic colonies

I. Dubé, 1980 .

Gene therapy for canine alpha-L-iduronidase deficiency: in utero adoptive transfer of genetically corrected hematopoietic progenitors results in engraftment but not amelioration of disease.

C. Lutzko, I. Dubé, A. Abrams-Ogg, 1999, Human gene therapy.

Deletion of the long arm of chromosome 5 in essential thrombocythemia.

I. Dubé, P. Pinkerton, G. Sher, 1992, Cancer genetics and cytogenetics.

Translocation (14;19) in acute biphenotypic leukemia.

T. McKeithan, I. Dubé, K. Carstairs, 1991, Cancer genetics and cytogenetics.

In vitro and in vivo effects of deferoxamine in neonatal acute leukemia.

X. H. Wang, Z. Estrov, E. Gelfand, 1987, Blood.

In utero injection of alpha-L-iduronidase-carrying retrovirus in canine mucopolysaccharidosis type I: infection of multiple tissues and neonatal gene expression.

M. R. Hough, C. Lutzko, Kin Chan, 2002, Human gene therapy.

Regional cancer cytogenetics: a report on 1,143 diagnostic cases.

I. Dubé, K. Carstairs, D. Bailey, 1997, Cancer genetics and cytogenetics.

A model for spontaneous B-lineage lymphomas in IgHmu-HOX11 transgenic mice.

M. R. Hough, S. Kamel‐Reid, I. Dardick, 1998, Proceedings of the National Academy of Sciences of the United States of America.

Loss of Ubr1 promotes aneuploidy and accelerates B-cell lymphomagenesis in TLX1/HOX11-transgenic mice

M. Lim, M. R. Hough, I. Dubé, 2006, Oncogene.

The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP96 and class I homeoprotein HOXA9

Keisuke Toyama, Reinhard Becher, Christine Morris, 1996, Nature Genetics.

Dysregulation of HOX11 by chromosome translocations in T-cell acute lymphoblastic leukemia: a paradigm for homeobox gene involvement in human cancer.

S. Kamel‐Reid, B. Lichty, I. Dubé, 1995, Leukemia & lymphoma.

Characterization and developmental expression of Tlx-1, the murine homolog of HOX11

S. Kamel‐Reid, K. Raju, I. Dubé, 1993, Mechanisms of Development.

A novel human homeobox gene lies at the chromosome 10 breakpoint in lymphoid neoplasias with chromosomal translocation t(10;14).

S. Raimondi, S. Kamel‐Reid, A. Carroll, 1991, Blood.

Molecular characterization of the t(10;14) translocation breakpoints in T‐cell acute lymphoblastic leukemia: Further evidence for illegitimate physiological recombination

S. Raimondi, M. Minden, A. Carroll, 1990, Genes, chromosomes & cancer.

p53 gene mutations in sequential oral epithelial dysplasias and squamous cell carcinomas

G. Bradley, R. Jordan, J. Regezi, 2000, The Journal of pathology.

Detection of residual acute lymphoblastic leukemia cells in cultures of bone marrow obtained during remission.

Z. Estrov, M. Freedman, I. Dubé, 1986, The New England journal of medicine.

Retroviral-mediated transfer and expression of the multidrug resistance protein 1 gene (MRP1) protect human hematopoietic cells from antineoplastic drugs.

C. K. Chan, A. Stewart, I. Dubé, 1999, Journal of hematotherapy & stem cell research.

Cytogenetic studies of haemopoietic colonies from patients with an initial diagnosis of acute lymphoblastic leukaemia

C. Eaves, I. Dubé, D. Kalousek, 1988, British journal of haematology.

Gene transfer into hematopoietic stem cells

C. Lutzko, I. Dubé, P. Chu, 1996 .

Constitutive expression and role in growth regulation of interleukin-1 and multiple cytokine receptors in a biphenotypic leukemic cell line.

M. Freedman, M. Letarte, I. Dubé, 1991, Blood.

Humoral immune response limits gene therapy in canine MPS I [letter]

C. Lutzko, H. Kiem, I. Dubé, 1996 .

Humoral immune response limits gene therapy in canine MPS I.

C. Lutzko, H. Kiem, I. Dubé, 1996, Blood.

Occupational history and involvement of chromosomes 5 and 7 in acute nonlymphocytic leukemia.

S. Narod, I. Dubé, Ian D. Dubé, 1989, Cancer genetics and cytogenetics.

Involvement of multiple signaling pathways in follicular lymphoma transformation: p38-mitogen-activated protein kinase as a target for therapy

Zhaosheng Lin, Kojo S J Elenitoba-Johnson, R. T. Abbott, 2003, Proceedings of the National Academy of Sciences of the United States of America.

Symposium highlights: Future prospects for gene therapy

D. Allan, I. Dubé, 1996 .

A reordering of human chromosome 19 long-arm DNA markers and identification of markers flanking the myotonic dystrophy locus.

Y. Nakamura, Y. Nakamura, A. Hunter, 1989, Genomics.

Location of breakpoints within the major breakpoint cluster region (bcr) in 33 patients with bcr rearrangement‐positive chronic myeloid leukemia (CML) with complex or absent Philadelphia chromosomes

T. McKeithan, I. Dubé, J. Dixon, 1989, Genes, chromosomes & cancer.

Characterization and molecular analysis of nondisjunction in 18 cases of trisomy 21 and leukemia

P. Jacobs, A. Zipursky, T. Hassold, 1992, Genes, chromosomes & cancer.

Adoptive transfer of genetically modified human hematopoietic stem cells into preimmune canine fetuses.

A. Stewart, C. Lutzko, I. Dubé, 1999, Experimental hematology.

Essential thrombocythemia with the Philadelphia chromosome and BCR-ABL gene rearrangement. An entity distinct from chronic myeloid leukemia and Philadelphia chromosome-negative essential thrombocythemia.

D. LeBrun, I. Dubé, P. Pinkerton, 1991, Cancer genetics and cytogenetics.

Breakpoints Involved in Deletions of the Long Arm of Chromosome 5 in Myelodysplasia and Acute Non-Lymphoblastic Leukemia do not Correlate with the Morphological Diagnosis.

I. Dubé, P. Pinkerton, S. Al-Jaouni, 1990, Leukemia & lymphoma.

Chromosome Abnormalities in Chronic Myeloid Leukaemia

I. Dubé, P. Pinkerton, R. Carter, 1990 .

Gene therapy: here to stay.

I. Dubé, D. Cournoyer, 1995, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

Unusual findings in two patients with acquired deletions of the long arm of chromosome 5 (5q-).

M. Lishner, I. Dubé, D. Amato, 2008, Clinical and laboratory haematology.

Chromosome abnormalities in chronic myeloid leukaemia. A model for acquired chromosome changes in haematological malignancy.

I. Dubé, P. Pinkerton, R. Carter, 1990, Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine.

Fractionation of Gene Modified Hematopoietic Autografts into Multiple Weekly Infusions Does Not Improve Engraftment in Unconditioned Canine Recipients.

C. Lutzko, I. Dubé, A. Abrams-Ogg, 1999, Hematology.

Engraftment of human chronic lymphocytic leukemia cells in SCID mice: in vivo and in vitro studies.

S. Kamel‐Reid, B. Lichty, I. Dubé, 1996, Leukemia.

A new variant translocation in acute promyelocytic leukaemia: molecular characterization and clinical correlation.

S. Kamel‐Reid, A. Zipursky, I. Dubé, 1996, Leukemia.

Clinical and pathological findings in dogs following supralethal total body irradiation with and without infusion of autologous long-term marrow culture cells.

J. Dick, S. Kamel‐Reid, V. Valli, 1993, Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.

Secondary acute non-lymphocytic leukemia with monosomy 7 arising 9 years after acute lymphoblastic leukemia in childhood.

I. Dubé, H. Solh, A. Poon, 1991, Cancer genetics and cytogenetics.