Anna Cappa

发表

Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors.

A. Mai, S. Minucci, C. Mercurio, 2010, Journal of medicinal chemistry.

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 2: Structure-Based Drug Design and Structure-Activity Relationship.

S. Minucci, C. Mercurio, L. Moretti, 2017, Journal of medicinal chemistry.

Discovery of Reversible Inhibitors of KDM1A Efficacious in Acute Myeloid Leukemia Models.

S. Minucci, C. Mercurio, C. So, 2020, ACS medicinal chemistry letters.

Tranylcypromine‐Based LSD1 Inhibitors: Structure‐Activity Relationships, Antiproliferative Effects in Leukemia, and Gene Target Modulation

A. Mai, S. Minucci, C. Mercurio, 2020, ChemMedChem.

A Simple Method for the Selective Deprotection of p-Methoxybenzyl Ethers by Cerium(III) Chloride Heptahydrate and Sodium Iodide.

Anna Cappa, E. Marcantoni, E. Torregiani, 1999, The Journal of organic chemistry.

Fast and highly efficient one-pot synthesis of 9-deazaxanthines

F. Leonetti, Anna Cappa, A. Carotti, 2003 .

Synthesis, biological activity and mechanistic insights of 1-substituted cyclopropylamine derivatives: a novel class of irreversible inhibitors of histone demethylase KDM1A.

A. Mai, S. Minucci, M. Tortorici, 2014, European journal of medicinal chemistry.

Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration.

S. Minucci, C. Mercurio, L. Moretti, 2017, Journal of medicinal chemistry.

Novel potent inhibitors of the histone demethylase KDM1A (LSD1), orally active in a murine promyelocitic leukemia model.

S. Minucci, C. Mercurio, M. Villa, 2017, Future medicinal chemistry.

Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent.

A. Mai, S. Minucci, C. Mercurio, 2016, Journal of medicinal chemistry.

Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo.

S. Minucci, P. Pelicci, R. Amici, 2014, Journal of medicinal chemistry.

Homo- and hetero-bivalent edrophonium-like ammonium salts as highly potent, dual binding site AChE inhibitors.

F. Leonetti, Anna Cappa, O. Nicolotti, 2008, Bioorganic & medicinal chemistry.

Synthesis of potential dual binding site acetylcholinesterase inhibitors through an efficient solid phase approach based on the Mitsunobu reaction

F. Leonetti, C. Maccallini, Anna Cappa, 2004 .