S. Gagliardi

发表

Synthesis and biological evaluation of N-hydroxyphenylacrylamides and N-hydroxypyridin-2-ylacrylamides as novel histone deacetylase inhibitors.

A. Mai, S. Minucci, C. Mercurio, 2010, Journal of medicinal chemistry.

Synthesis and biological characterization of spiro[2H-(1,3)-benzoxazine-2,4'-piperidine] based histone deacetylase inhibitors.

S. Minucci, C. Mercurio, M. Varasi, 2013, European journal of medicinal chemistry.

Efficient continuous flow synthesis of hydroxamic acids and suberoylanilide hydroxamic acid preparation.

Daniele Vigo, Marisa Martinelli, Daniele Passarella, 2009, The Journal of organic chemistry.

Synthesis of (+)-dumetorine and congeners by using flow chemistry technologies.

D. Passarella, S. Gagliardi, Anna Rencurosi, 2011, Chemistry.

Efficient Continuous Flow Synthesis of Hydroxamic Acids and Suberoylanilide Hydroxamic Acid (VII) Preparation.

D. Passarella, D. Vigo, S. Gagliardi, 2009 .

Synthesis and biological evaluation of novel dimiracetam derivatives useful for the treatment of neuropathic pain.

C. Ghelardini, C. Parini, S. Gagliardi, 2008, Bioorganic & medicinal chemistry.

Chiral Resolution and Pharmacological Characterization of the Enantiomers of the Hsp90 Inhibitor 2‐Amino‐7‐[4‐fluoro‐2‐(3‐pyridyl)phenyl]‐4‐methyl‐7,8‐dihydro‐6H‐quinazolin‐5‐one Oxime

S. Minucci, C. Mercurio, R. Amici, 2014, ChemMedChem.

Novel bone antiresorptive agents that selectively inhibit the osteoclast V-H+-ATPase.

C. Parini, S. Gagliardi, M. Gowen, 2001, Farmaco.

Selective inhibition of osteoclast vacuolar H(+)-ATPase.

S. Gagliardi, C. Farina, 2002, Current pharmaceutical design.

A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress

G. Aldini, G. Vistoli, E. Gilardoni, 2018, The Journal of clinical investigation.

5-(5,6-Dichloro-2-indolyl)-2-methoxy-2,4-pentadienamides: novel and selective inhibitors of the vacuolar H+-ATPase of osteoclasts with bone antiresorptive activity.

P. Nambi, C. Parini, S. Gagliardi, 1998, Journal of medicinal chemistry.

Synthesis, biological characterization and molecular modeling insights of spirochromanes as potent HDAC inhibitors.

S. Minucci, C. Mercurio, L. Moretti, 2016, European journal of medicinal chemistry.

Synthesis and Biological Characterization of Amidopropenyl Hydroxamates as HDAC Inhibitors

A. Mai, S. Minucci, C. Mercurio, 2010, ChemMedChem.

AN UNUSUALLY FACILE PREPARATION OF 21-ALKOXYDERIVATIVES OF BAFILOMYCIN A1

S. Gagliardi, P. Gatti, C. Farina, 1997 .

Replacement of the quinoline system in 2-phenyl-4-quinolinecarboxamide NK-3 receptor antagonists.

H. Sarau, S. Gagliardi, M. Artico, 1999, Farmaco.

A novel series of metabotropic glutamate receptor 5 negative allosteric modulators based on a 4,5,6,7-tetrahydropyrazolo[1,5-a]pyridine core.

D. Charvin, S. Gagliardi, E. Le Poul, 2013, Bioorganic & medicinal chemistry letters.

Spiro[chromane‐2,4′‐piperidine]‐Based Histone Deacetylase Inhibitors with Improved in vivo Activity

S. Minucci, C. Mercurio, M. Varasi, 2012, ChemMedChem.

Synthesis of photoactivable inhibitors of osteoclast vacuolar ATPase.

S. Dallavalle, C. Parini, S. Gagliardi, 2003, Bioorganic & medicinal chemistry.

Selective inhibitors of vacuolar H+-ATPase of osteoclasts with bone antiresorptive activity

S. Gagliardi, C. Farina, 1999 .

The discovery of biaryl carboxamides as novel small molecule agonists of the motilin receptor.

Michael A. Briggs, G. Macdonald, G. Sanger, 2008, Bioorganic & medicinal chemistry letters.

Reaction of Grignard reagents with carbonyl compounds under continuous flow conditions

Daniele Vigo, Marisa Martinelli, Daniele Passarella, 2010 .

Microwave-assisted solvent-free synthesis of a quinoline-3,4-dicarboximide library on inorganic solid supports

Nickolas Regalia, S. Gagliardi, U. Piarulli, 2004 .

Discovery of a novel antitumor benzolactone enamide class that selectively inhibits mammalian vacuolar-type (H+)-atpases.

J. Kim, M. Boyd, E. J. Bowman, 2001, The Journal of pharmacology and experimental therapeutics.

Cinnamic anilides as new mitochondrial permeability transition pore inhibitors endowed with ischemia-reperfusion injury protective effect in vivo.

S. Minucci, P. Pelicci, R. Amici, 2014, Journal of medicinal chemistry.

Inhibition of Plasmodium falciparum pH regulation by small molecule indole derivatives results in rapid parasite death.

Donelly A van Schalkwyk, Carlo Farina, K. Saliba, 2010, Biochemical pharmacology.

Chemistry and Structure—Activity Relationships of Bafilomycin A1, a Potent and Selective Inhibitor of the Vacuolar H+‐ATPase

S. Gagliardi, C. Farina, M. Rees, 2000 .

Chemistry and Structure Activity Relationships of Bafilomycin A 1, A Potent and Selective Inhibitor of the Vacuolar H+-ATPase

S. Gagliardi, M. Rees, C. Farinaa, 1999, Current Medicinal Chemistry.

(2Z,4E)-5-(5,6-dichloro-2-indolyl)-2-methoxy-N-(1,2,2,6,6- pentamethylpiperidin-4-yl)-2,4-pentadienamide, a novel, potent and selective inhibitor of the osteoclast V-ATPase.

C. Parini, S. Gagliardi, D. Zembryki, 1998, Bioorganic & medicinal chemistry letters.

Synthesis and structure-activity relationships of bafilomycin A1 derivatives as inhibitors of vacuolar H+-ATPase.

S. Gagliardi, P. Gatti, C. Farina, 1998, Journal of medicinal chemistry.

Stepwise modulation of neurokinin-3 and neurokinin-2 receptor affinity and selectivity in quinoline tachykinin receptor antagonists.

F E Blaney, H. Sarau, F. Blaney, 2001, Journal of medicinal chemistry.

Identification of small molecule agonists of the motilin receptor.

Alan Wise, G. Macdonald, A. Muir, 2008, Bioorganic & medicinal chemistry letters.

Synthesis and antihypertensive activity of pyran oxygen and amide nitrogen replacement analogues of the potassium channel activator cromakalim.

S. Gagliardi, G. Stemp, J. M. Evans, 1991, Journal of medicinal chemistry.

Chemistry and structure activity relationships of bafilomycin A1, a potent and selective inhibitor of the vacuolar H+-ATPase.

S. Gagliardi, C. Farina, M. Rees, 1999, Current Medicinal Chemistry.

Spiro[chromane‐2,4′‐piperidine]‐Based Histone Deacetylase Inhibitors with Improved in vivo Activity

S. Minucci, C. Mercurio, M. Varasi, 2012, ChemMedChem.