S. Terracciano

发表

Synthesis and biological activity of cyclotetrapeptide analogues of the natural HDAC inhibitor FR235222.

G. Bifulco, R. Riccio, P. Gallinari, 2010, Bioorganic & medicinal chemistry.

Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E₂ synthase-1 enzyme (mPGES-1).

G. Bifulco, O. Werz, R. Riccio, 2014, European journal of medicinal chemistry.

Structural Insights for the Optimization of Dihydropyrimidin-2(1H)-one Based mPGES-1 Inhibitors.

G. Bifulco, O. Werz, R. Riccio, 2015, ACS medicinal chemistry letters.

Structure‐Based Design of Microsomal Prostaglandin E2 Synthase‐1 (mPGES‐1) Inhibitors using a Virtual Fragment Growing Optimization Scheme

G. Bifulco, E. Novellino, O. Werz, 2016, ChemMedChem.

Glucopyranosylbianthrones from the Algerian Asphodelus tenuifolius: Structural Insights and Biological Evaluation on Melanoma Cancer Cells.

G. Bifulco, S. Terracciano, I. Bruno, 2018, Journal of natural products.

Molecular modeling studies toward the structural optimization of new cyclopeptide-based HDAC inhibitors modeled on the natural product FR235222.

G. Bifulco, R. Riccio, S. Terracciano, 2008, Bioorganic & medicinal chemistry.

Dimeric and trimeric triazole based molecules as a new class of Hsp90 molecular chaperone inhibitors.

G. Bifulco, R. Riccio, S. Terracciano, 2013, European journal of medicinal chemistry.

Design, Synthesis, and Biological Activity of Hydroxamic Tertiary Amines as Histone Deacetylase Inhibitors

G. Bifulco, R. Riccio, S. Terracciano, 2012, ChemMedChem.

A Combinatorial Virtual Screening Approach Driving the Synthesis of 2,4‐Thiazolidinedione‐Based Molecules as New Dual mPGES‐1/5‐LO Inhibitors

G. Bifulco, O. Werz, S. Terracciano, 2020, ChemMedChem.

Targeting the Hsp90 C-terminal domain by the chemically accessible dihydropyrimidinone scaffold.

G. Bifulco, R. Riccio, S. Terracciano, 2015, Chemical communications.

New dihydropyrimidin-2(1H)-one based Hsp90 C-terminal inhibitors

G. Bifulco, R. Riccio, C. Saturnino, 2016 .

Discovery and synthesis of the first selective BAG domain modulator of BAG3 as an attractive candidate for the development of a new class of chemotherapeutics.

G. Bifulco, R. Riccio, M. Turco, 2018, Chemical communications.

Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain

G. Bifulco, R. Riccio, S. Terracciano, 2018, Scientific Reports.

Targeting mPGES-1 by a Combinatorial Approach: Identification of the Aminobenzothiazole Scaffold to Suppress PGE2 Levels.

G. Bifulco, O. Werz, A. Koeberle, 2020, ACS medicinal chemistry letters.

Synthesis of new mono and bis amides projected as potential histone deacetylase (HDAC) inhibitors

G. Bifulco, R. Riccio, S. Terracciano, 2010 .

Identification of the 2-Benzoxazol-2-yl-phenol Scaffold as New Hit for JMJD3 Inhibition.

U. Oppermann, C. Johansson, M. Sala, 2019, ACS medicinal chemistry letters.

Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation

Maria T. Potenza, G. Bifulco, O. Werz, 2022, Molecules.

Conformationally locked calixarene-based histone deacetylase inhibitors.

G. Bifulco, C. Gaeta, P. Neri, 2010, Organic letters.

Structural Refinement of 2,4-Thiazolidinedione Derivatives as New Anticancer Agents Able to Modulate the BAG3 Protein

G. Bifulco, S. Terracciano, I. Bruno, 2022, Molecules.

Identification of 2,4,5-trisubstituted-2,4-dihydro-3H-1,2,4-triazol-3-one-based small molecules as selective BRD9 binders.

G. Bifulco, S. Terracciano, I. Bruno, 2022, European journal of medicinal chemistry.

Protein Preparation Automatic Protocol for High-Throughput Inverse Virtual Screening: Accelerating the Target Identification by Computational Methods

Simona De Vita, Gianluigi Lauro, Dafne Ruggiero, 2019, J. Chem. Inf. Model..

Cyclic Peptoids as Mycotoxin Mimics: An Exploration of Their Structural and Biological Properties.

C. Tedesco, G. Della Sala, C. Costabile, 2017, The Journal of organic chemistry.

Hsp90 Activity Modulation by Plant Secondary Metabolites

S. Terracciano, N. de Tommasi, A. Braca, 2015, Planta Medica.

Hsp 90 Activity Modulation by Plant Secondary Metabolites

S. Terracciano, A. Braca, N. Tommasi, 2015 .

Discovery of new molecular entities able to strongly interfere with Hsp90 C-terminal domain

G. Bifulco, R. Riccio, S. Terracciano, 2018, Scientific Reports.

Total synthesis, NMR solution structure, and binding model of the potent histone deacetylase inhibitor FR235222.

G. Bifulco, L. Gomez‐Paloma, S. Terracciano, 2006, Angewandte Chemie.

9H-Purine Scaffold Reveals Induced-Fit Pocket Plasticity of the BRD9 Bromodomain

G. Bifulco, P. Filippakopoulos, S. Picaud, 2015, Journal of medicinal chemistry.

Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1.

A. Tosco, S. Terracciano, I. Bruno, 2008, European journal of cancer.

Discovery of noscapine derivatives as potential β-tubulin inhibitors.

G. Bifulco, P. Salehi, S. Terracciano, 2020, Bioorganic & medicinal chemistry letters.

Synthesis, solution structure, and bioactivity of six new simplified analogues of the natural cyclodepsipeptide jaspamide.

Stefania Terracciano, Giuseppe Bifulco, Elvira Avallone, 2005, Bioorganic & medicinal chemistry.

Identification of novel microsomal prostaglandin E2 synthase-1 (mPGES-1) lead inhibitors from Fragment Virtual Screening.

G. Bifulco, E. Novellino, O. Werz, 2017, European journal of medicinal chemistry.

Structural basis for the design and synthesis of selective HDAC inhibitors.

G. Bifulco, R. Riccio, S. Terracciano, 2013, Bioorganic & medicinal chemistry.

Identification of the key structural elements of a dihydropyrimidinone core driving toward more potent Hsp90 C-terminal inhibitors.

G. Bifulco, R. Riccio, C. Saturnino, 2016, Chemical communications.

Identification by Inverse Virtual Screening of magnolol-based scaffold as new tankyrase-2 inhibitors.

G. Bifulco, R. Riccio, S. Terracciano, 2018, Bioorganic & medicinal chemistry.

Identification of Lead Compounds as Inhibitors of STAT3: Design, Synthesis and Bioactivity

P. Longo, C. Saturnino, M. Sinicropi, 2015, Molecular informatics.

Identification of 2-Aminoacyl-1,3,4-thiadiazoles as Prostaglandin E2 and Leukotriene Biosynthesis Inhibitors

G. Bifulco, O. Werz, S. Terracciano, 2022, ACS medicinal chemistry letters.

From Natural Compounds to Bioactive Molecules through NMR and In Silico Methodologies

S. Terracciano, I. Bruno, Simona De Vita, 2020 .

Discovery of new potent molecular entities able to inhibit mPGES-1.

G. Bifulco, O. Werz, A. Koeberle, 2018, European journal of medicinal chemistry.

Introducing structure-based three-dimensional pharmacophore models for accelerating the discovery of selective BRD9 binders.

G. Bifulco, S. Terracciano, I. Bruno, 2021, Bioorganic chemistry.

Chemistry and biology of anti-inflammatory marine natural products: molecules interfering with cyclooxygenase, NF-kappaB and other unidentified targets.

L. Gomez‐Paloma, R. Riccio, M. Monti, 2006, Current medicinal chemistry.

Design and Synthesis of Cyclopeptide Analogues of the Potent Histone Deacetylase Inhibitor FR235222

L. Gomez‐Paloma, S. Khochbin, S. Terracciano, 2007, ChemMedChem.

Identification of 2-(thiophen-2-yl)acetic Acid-Based Lead Compound for mPGES-1 Inhibition

G. Bifulco, O. Werz, S. Terracciano, 2021, Frontiers in Chemistry.

Synthetic and pharmacological studies on new simplified analogues of the potent actin-targeting Jaspamide.

G. Bifulco, Charles D Smith, V. Sepe, 2008, Bioorganic & medicinal chemistry.

Synthesis, conformational analysis, and cytotoxicity of new analogues of the natural cyclodepsipeptide jaspamide.

G. Bifulco, L. Gomez‐Paloma, R. Riccio, 2004, Journal of natural products.

Can Small Chemical Modifications of Natural Pan-inhibitors Modulate the Biological Selectivity? The Case of Curcumin Prenylated Derivatives Acting as HDAC or mPGES-1 Inhibitors.

G. Bifulco, O. Werz, A. Koeberle, 2015, Journal of natural products.

2-Substituted 1,5-benzothiazepine-based HDAC inhibitors exert anticancer activities on human solid and acute myeloid leukemia cell lines.

G. Bifulco, A. Nebbioso, S. Terracciano, 2023, Bioorganic & medicinal chemistry.

A multidisciplinary functional proteomics-aided strategy as a tool for the profiling of a novel cytotoxic thiadiazolopyrimidone.

S. Terracciano, I. Bruno, A. Petrella, 2023, Bioorganic chemistry.

Chemistry and Biology of Anti-Inflammatory Marine Natural Products. Phospholipase A2 Inhibitors

L. Gomez‐Paloma, R. Riccio, M. Monti, 2005 .

Exploration of the dihydropyrimidine scaffold for the development of new potential anti-inflammatory agents blocking prostaglandin E₂ synthase-1 enzyme (mPGES-1).

G. Bifulco, O. Werz, R. Riccio, 2014, European journal of medicinal chemistry.

Structure‐Based Design of Microsomal Prostaglandin E2 Synthase‐1 (mPGES‐1) Inhibitors using a Virtual Fragment Growing Optimization Scheme

G. Bifulco, E. Novellino, O. Werz, 2016, ChemMedChem.